| Investigating the Influence of ANTXR2 Gene Mutations on Protective Antigen Binding for Heightened Anthrax Resistance. | Investigating the Influence of ANTXR2 Gene Mutations on Protective Antigen Binding for Heightened Anthrax Resistance.
Archana CA, Sekar YS, Suresh KP, Subramaniam S, Sagar N, Rani S, Anandakumar J, Pandey RK, Barman NN, Patil SS., Free PMC Article | 05/28/2024 |
| Sex Hormone-regulated CMG2 Is Involved in Breast and Prostate Cancer Progression. | Sex Hormone-regulated CMG2 Is Involved in Breast and Prostate Cancer Progression.
Fang Z, Killick C, Halfpenny C, Frewer N, Frewer KA, Ruge F, Jiang WG, Ye L., Free PMC Article | 11/5/2022 |
| The Capillary Morphogenesis Gene 2 Triggers the Intracellular Hallmarks of Collagen VI-Related Muscular Dystrophy. | The Capillary Morphogenesis Gene 2 Triggers the Intracellular Hallmarks of Collagen VI-Related Muscular Dystrophy.
Castroflorio E, Pérez Berná AJ, López-Márquez A, Badosa C, Loza-Alvarez P, Roldán M, Jiménez-Mallebrera C., Free PMC Article | 08/6/2022 |
| Anthrax toxin receptor 2 is a potential therapeutic target for non-small cell lung carcinoma with MET exon 14 skipping mutations. | Anthrax toxin receptor 2 is a potential therapeutic target for non-small cell lung carcinoma with MET exon 14 skipping mutations.
Yamaguchi M, Hirai S, Idogawa M, Uchida H, Sakuma Y. | 07/30/2022 |
| Novel variation in ANTXR2 gene causing hyaline fibromatosis syndrome: A report from India. | Novel variation in ANTXR2 gene causing hyaline fibromatosis syndrome: A report from India.
Chaudhry C, Kaur P, Srivastava P, Panigrahi I, Kaur A. | 12/25/2021 |
| Multiple stages of evolutionary change in anthrax toxin receptor expression in humans. | Multiple stages of evolutionary change in anthrax toxin receptor expression in humans.
Choate LA, Barshad G, McMahon PW, Said I, Rice EJ, Munn PR, Lewis JJ, Danko CG., Free PMC Article | 12/18/2021 |
| Genetic deletion of CMG2 exacerbates systemic-to-pulmonary shunt-induced pulmonary arterial hypertension. | Genetic deletion of CMG2 exacerbates systemic-to-pulmonary shunt-induced pulmonary arterial hypertension.
Meng L, Yuan W, Chi H, Han R, Zhang Y, Pan X, Meng J, Liu Y, Song J, Zhong J, Liu X. | 07/24/2021 |
| Enhanced Collagen Deposition in the Duodenum of Patients with Hyaline Fibromatosis Syndrome and Protein Losing Enteropathy. | Enhanced Collagen Deposition in the Duodenum of Patients with Hyaline Fibromatosis Syndrome and Protein Losing Enteropathy.
van Rijn JM, Werner L, Aydemir Y, Spronck JMA, Pode-Shakked B, van Hoesel M, Shimshoni E, Polak-Charcon S, Talmi L, Eren M, Weiss B, H J Houwen R, Barshack I, Somech R, Nieuwenhuis EES, Sagi I, Raas-Rothschild A, Middendorp S, Shouval DS., Free PMC Article | 04/3/2021 |
| A Canstatin-Derived Peptide Provides Insight into the Role of Capillary Morphogenesis Gene 2 in Angiogenic Regulation and Matrix Uptake. | A Canstatin-Derived Peptide Provides Insight into the Role of Capillary Morphogenesis Gene 2 in Angiogenic Regulation and Matrix Uptake.
Finnell JG, Tsang TM, Cryan L, Garrard S, Lee SL, Ackroyd PC, Rogers MS, Christensen KA. | 02/13/2021 |
| Protective effect of anthrax toxin receptor 2 polymorphism rs4333130 against the risk of ankylosing spondylitis. | Protective effect of anthrax toxin receptor 2 polymorphism rs4333130 against the risk of ankylosing spondylitis.
Xu H, Qu Y., Free PMC Article | 08/13/2020 |
| Elevation of ANTXR2 promotes endometriotic cell adhesion, proliferation, and angiogenesis. Furthermore, hypoxia is the driving force for ANTXR2 upregulation via altering histone modification of ANTXR2. | Targeting Anthrax Toxin Receptor 2 Ameliorates Endometriosis Progression.
Lin SC, Lee HC, Hsu CT, Huang YH, Li WN, Hsu PL, Wu MH, Tsai SJ., Free PMC Article | 12/14/2019 |
| CMG2 is an indicator of poor prognosis of glioma patients and also a stimulator of cell cycle progression in cultured glioma cells. | Capillary morphogenesis protein 2 is a novel prognostic biomarker and plays oncogenic roles in glioma.
Tan J, Liu M, Zhang JY, Yao YL, Wang YX, Lin Y, Song K, Tan J, Wu JR, Cui YH, Wang Y, Bian XW. | 11/2/2019 |
| Study provides evidence to reinforce the previous hypothesis that missense mutations in exons 1-12 in ANTXR2 and mutations leading to a premature stop codon lead to the severe form of the disease, while missense pathogenic variants in exons 13-17 lead to the mild form of hyaline fibromatosis syndrome. [review] | Hyaline fibromatosis syndrome: Clinical update and phenotype-genotype correlations.
Casas-Alba D, Martínez-Monseny A, Pino-Ramírez RM, Alsina L, Castejón E, Navarro-Vilarrubí S, Pérez-Dueñas B, Serrano M, Palau F, García-Alix A. | 10/12/2019 |
| CMG2 promoted the invasion of glioma cells | Promotive effects of capillary morphogenetic protein 2 on glioma cell invasion and the molecular mechanism.
Xu Y, He Y, Xu W, Lu T, Liang W, Jin W. | 08/31/2019 |
| CMG2 promotes GC progression by maintaining GCSLCs and can serve as a new prognostic indicator and a target for human GC therapy. | Capillary morphogenesis gene 2 maintains gastric cancer stem-like cell phenotype by activating a Wnt/β-catenin pathway.
Ji C, Yang L, Yi W, Xiang D, Wang Y, Zhou Z, Qian F, Ren Y, Cui W, Zhang X, Zhang P, Wang JM, Cui Y, Bian X., Free PMC Article | 03/2/2019 |
| Results from hyaline fibromatosis syndrome (HFS) patients with consanguineous background identified a novel homozygous frameshift deletion c.969del (p.Ile323Metfs*14), a previously reported mutation c.134 T > C (p.Leu45Pro) and a recurrent homozygous frameshift mutation c.1073dup (p.Ala359Cysfs*13). These findings improves the understanding of a recurrent mutation in HFS. | The genetic basis of hyaline fibromatosis syndrome in patients from a consanguineous background: a case series.
Youssefian L, Vahidnezhad H, Touati A, Ziaee V, Saeidian AH, Pajouhanfar S, Zeinali S, Uitto J., Free PMC Article | 03/2/2019 |
| this study shows no association between ANTXR2 polymorphisms and ankylosing spondylitis susceptibility in a Chinese Han population, but meta-analysis showed that rs4389526 in the ANTXR2 gene was weakly associated with AS susceptibility in both Caucasian and Chinese Han patients. | Case-Control Study and Meta-Analysis Show a Weak Association between ANTXR2 Polymorphisms and Ankylosing Spondylitis in Chinese Han.
Hu J, Du L, Su W, Liu S, Deng J, Cao Q, Yuan G, Kijlstra A, Yang P., Free PMC Article | 01/12/2019 |
| A decreased CMG2 expression is a negative prognostic factor for soft tissue sarcoma patients. | CMG2 Expression Is an Independent Prognostic Factor for Soft Tissue Sarcoma Patients.
Greither T, Wedler A, Rot S, Keßler J, Kehlen A, Holzhausen HJ, Bache M, Würl P, Taubert H, Kappler M., Free PMC Article | 07/28/2018 |
| Results identified Gly116Val mutation in ANTXR2 associated with hyaline fibromatosis syndrome. | Diagnosis implications of the whole genome sequencing in a large Lebanese family with hyaline fibromatosis syndrome.
Haidar Z, Temanni R, Chouery E, Jithesh P, Liu W, Al-Ali R, Wang E, Marincola FM, Jalkh N, Haddad S, Haidar W, Chouchane L, Mégarbané A., Free PMC Article | 09/23/2017 |
| Stability of domain 4 of the anthrax toxin protective antigen and the effect of the VWA domain of CMG2 on stability | Stability of domain 4 of the anthrax toxin protective antigen and the effect of the VWA domain of CMG2 on stability.
Mamillapalli S, Miyagi M, Bann JG., Free PMC Article | 07/15/2017 |
| expression does not affect cytotoxicity to anthrax toxin | ANTXR-1 and -2 independent modulation of a cytotoxicity mediated by anthrax toxin in human cells.
Fujikura D, Toyomane K, Kamiya K, Mutoh M, Mifune E, Ohnuma M, Higashi H., Free PMC Article | 06/24/2017 |
| study examines 4 cases with clinical features of hyaline fibromatosis syndrome; identified a previously unreported splice junction mutation (c.946-2A-->G in intron 11) and a recurrent founder mutation ( c.1074delT) | Hyaline Fibromatosis Syndrome: A Novel Mutation and Recurrent Founder Mutation in the CMG2/ANTXR2 Gene.
Youssefian L, Vahidnezhad H, Aghighi Y, Ziaee V, Zeinali S, Abiri M, Uitto J. | 03/4/2017 |
| This study reports a novel association between ANTXR2 and ankylosing spondylitis in the Han Chinese. | A complex role of anthrax toxin receptor 2 polymorphisms and capillary morphogenesis protein 2 in ankylosing spondylitis pathogenesis.
Zhang Z, Yu K, Dai D, Yuan F, Liang F, Liu N, Xi Y, Sun YY. | 02/25/2017 |
| Case Report: systemic hyalinosis with a heterozygous mutation in CMG2. | Systemic Hyalinosis With Heterozygous CMG2 Mutations: A Case Report and Review of Literature.
Rahvar M, Teng J, Kim J. | 01/28/2017 |
| The association between ANTXR2 rs4333130 and ankylosing spondylitis was independent of HLA-B27 status. Clinical disease severity scores (BASDAI and BASFI) and pain score were higher in ANTXR2 rs4333130 CT genotype. | Determination of IL1 R2, ANTXR2, CARD9, and SNAPC4 single nucleotide polymorphisms in Iranian patients with ankylosing spondylitis.
Momenzadeh P, Mahmoudi M, Beigy M, Garshasbi M, Vodjdanian M, Farazmand A, Jamshidi AR. | 01/14/2017 |