| Experimental validation and pan-cancer analysis identified COL10A1 as a novel oncogene and potential therapeutic target in prostate cancer. | Experimental validation and pan-cancer analysis identified COL10A1 as a novel oncogene and potential therapeutic target in prostate cancer.
Xu S, Liu D, Qin Z, Liang Z, Xie H, Yi B, Wang K, Lin G, Liu R, Yang K, Xu Y, Zhang H., Free PMC Article | 01/29/2024 |
| COL10A1 promotes tumorigenesis by modulating CD276 in pancreatic adenocarcinoma. | COL10A1 promotes tumorigenesis by modulating CD276 in pancreatic adenocarcinoma.
Xu Q, Zheng J, Su Z, Chen B, Gu S., Free PMC Article | 11/21/2023 |
| COL10A1 is a potential immunotherapy biomarker associated with immune infiltration and deficient mismatch repair in colon cancer. | COL10A1 is a potential immunotherapy biomarker associated with immune infiltration and deficient mismatch repair in colon cancer.
Cai S, Sun Z, Yan Y, Li W, Wu Q. | 09/23/2023 |
| Natural history and genetic spectrum of the Turkish metaphyseal dysplasia cohort, including rare types caused by biallelic COL10A1, COL2A1, and LBR variants. | Natural history and genetic spectrum of the Turkish metaphyseal dysplasia cohort, including rare types caused by biallelic COL10A1, COL2A1, and LBR variants.
Tüysüz B, Kasap B, Sarıtaş M, Alkaya DU, Bozlak S, Kıykım A, Durmaz A, Yıldırım T, Akpınar E, Apak H, Vural M. | 01/14/2023 |
| Bioinformatics-Based Analysis: Noncoding RNA-Mediated COL10A1 Is Associated with Poor Prognosis and Immune Cell Infiltration in Pancreatic Cancer. | Bioinformatics-Based Analysis: Noncoding RNA-Mediated COL10A1 Is Associated with Poor Prognosis and Immune Cell Infiltration in Pancreatic Cancer.
Liu Q, Zhao H, Guo Y, Zhang K, Shang F, Liu T., Free PMC Article | 10/1/2022 |
| High COL10A1 expression potentially contributes to poor outcomes in gastric cancer with the help of LEF1 and Wnt2. | High COL10A1 expression potentially contributes to poor outcomes in gastric cancer with the help of LEF1 and Wnt2.
Zhang M, Jin M, Gao Z, Yu W, Zhang W., Free PMC Article | 09/24/2022 |
| VSNL1 Promotes Cell Proliferation, Migration, and Invasion in Colorectal Cancer by Binding with COL10A1. | VSNL1 Promotes Cell Proliferation, Migration, and Invasion in Colorectal Cancer by Binding with COL10A1.
He C, Liu W, Xiong Y, Wang Y, Pan L, Luo L, Tu Y, Song R, Chen W. | 04/9/2022 |
| Identification of a novel COL10A1: c.1952 G>T variant in a family with Schmid metaphyseal chondrodysplasia and development of a noninvasive prenatal testing method. | Identification of a novel COL10A1: c.1952 G>T variant in a family with Schmid metaphyseal chondrodysplasia and development of a noninvasive prenatal testing method.
Ye Y, Li W, Wang G, Zhan L, Lin J, Li T, Zhang J., Free PMC Article | 03/26/2022 |
| COL10A1 is a novel factor in the development of choroidal neovascularization. | COL10A1 is a novel factor in the development of choroidal neovascularization.
Lv D, Chen D, Wang Z, Cui Z, Ma JH, Ji S, Chen J, Tang S. | 03/12/2022 |
| Differentiation of Hypertrophic Chondrocytes from Human iPSCs for the In Vitro Modeling of Chondrodysplasias. | Differentiation of Hypertrophic Chondrocytes from Human iPSCs for the In Vitro Modeling of Chondrodysplasias.
Pretemer Y, Kawai S, Nagata S, Nishio M, Watanabe M, Tamaki S, Alev C, Yamanaka Y, Xue JY, Wang Z, Fukiage K, Tsukanaka M, Futami T, Ikegawa S, Toguchida J., Free PMC Article | 12/11/2021 |
| Analysis of Collagen type X alpha 1 (COL10A1) expression and prognostic significance in gastric cancer based on bioinformatics. | Analysis of Collagen type X alpha 1 (COL10A1) expression and prognostic significance in gastric cancer based on bioinformatics.
Chen S, Wei Y, Liu H, Gong Y, Zhou Y, Yang H, Tang L., Free PMC Article | 11/22/2021 |
| Genome-Scale Analysis Identifies Novel Transcript-Variants in Esophageal Adenocarcinoma. | Genome-Scale Analysis Identifies Novel Transcript-Variants in Esophageal Adenocarcinoma.
Purkayastha BPD, Chan ER, Ravillah D, Ravi L, Gupta R, Canto MI, Wang JS, Shaheen NJ, Willis JE, Chak A, Varadan V, Guda K., Free PMC Article | 09/11/2021 |
| MiR-218 affects hypertrophic differentiation of human mesenchymal stromal cells during chondrogenesis via targeting RUNX2, MEF2C, and COL10A1. | MiR-218 affects hypertrophic differentiation of human mesenchymal stromal cells during chondrogenesis via targeting RUNX2, MEF2C, and COL10A1.
Melnik S, Gabler J, Dreher SI, Hecht N, Hofmann N, Großner T, Richter W., Free PMC Article | 08/7/2021 |
| Collagen Type X Alpha 1 (COL10A1) Contributes to Cell Proliferation, Migration, and Invasion by Targeting Prolyl 4-Hydroxylase Beta Polypeptide (P4HB) in Breast Cancer. | Collagen Type X Alpha 1 (COL10A1) Contributes to Cell Proliferation, Migration, and Invasion by Targeting Prolyl 4-Hydroxylase Beta Polypeptide (P4HB) in Breast Cancer.
Yang W, Wu X, Zhou F., Free PMC Article | 06/5/2021 |
| Bioinformatics analysis of prognostic significance of COL10A1 in breast cancer. | Bioinformatics analysis of prognostic significance of COL10A1 in breast cancer.
Zhang M, Chen H, Wang M, Bai F, Wu K., Free PMC Article | 03/20/2021 |
| Effect of miR-26a-5p on gastric cancer cell proliferation, migration and invasion by targeting COL10A1. | Effect of miR-26a-5p on gastric cancer cell proliferation, migration and invasion by targeting COL10A1.
Li HH, Wang JD, Wang W, Wang HF, Lv JQ. | 02/13/2021 |
| RNAseq-Based Prioritization Revealed COL6A5, COL8A1, COL10A1 and MIR146A as Common and Differential Susceptibility Biomarkers for Psoriasis and Psoriatic Arthritis: Confirmation from Genotyping Analysis of 1417 Italian Subjects. | RNAseq-Based Prioritization Revealed COL6A5, COL8A1, COL10A1 and MIR146A as Common and Differential Susceptibility Biomarkers for Psoriasis and Psoriatic Arthritis: Confirmation from Genotyping Analysis of 1417 Italian Subjects.
Caputo V, Strafella C, Termine A, Campione E, Bianchi L, Novelli G, Giardina E, Cascella R., Free PMC Article | 02/13/2021 |
| Two novel mutations were identified in the present study, which will facilitate diagnosis of Schmid-type metaphyseal chondrodysplasia and further expand the spectrum of the COL10A1 mutations associated with MCDS patients | Identification of two novel COL10A1 heterozygous mutations in two Chinese pedigrees with Schmid-type metaphyseal chondrodysplasia.
Kong L, Shi L, Wang W, Zuo R, Wang M, Kang Q., Free PMC Article | 02/15/2020 |
| MiR-384 down-regulated COL10A1 expression in the non-small cell lung cancer cells. | MiR-384 induces apoptosis and autophagy of non-small cell lung cancer cells through the negative regulation of Collagen α-1(X) chain gene.
Guo Q, Zheng M, Xu Y, Wang N, Zhao W., Free PMC Article | 02/1/2020 |
| three polymorphisms located in COL6A5, COL8A1, and COL10A1 were investigated as potential susceptibility biomarkers for atopic eczema. | Atopic Eczema: Genetic Analysis of COL6A5, COL8A1, and COL10A1 in Mediterranean Populations.
Strafella C, Caputo V, Minozzi G, Milano F, Arcangeli M, Sobhy N, Abdelmaksood R, Hashad D, Vakirlis E, Novelli G, Cascella R, Giardina E., Free PMC Article | 01/4/2020 |
| Schmid type metaphyseal chondrodysplasia (SMCD) is a rare skeletal dysplasia, characterized by short stature, short limbs, bowing of the legs, and radiographic features of metaphyseal irregularities with fraying and splaying, more severe at the knee. It is caused by mutations of the COL10A1 gene. | Schmid Type Metaphyseal Chondrodysplasia with a Novel COL10A1 Mutation.
Goyal M, Gupta A, Choudhary A, Bhandari A. | 12/7/2019 |
| This first report of individuals with a homozygous variant in COL10A1 defines a new type of autosomal recessive skeletal dysplasia. The observations in COL10A1 variant carriers suggest a phenotypic overlap between the mildest forms of metaphyseal chondrodysplasia, Schmid type (MCDS) and idiopathic short stature | Autosomal recessive chondrodysplasia with severe short stature caused by a biallelic COL10A1 variant.
Ain NU, Makitie O, Naz S. | 09/21/2019 |
| the disease mechanism involves the misfolding of the mutant protein causing increased endoplasmic reticulum (ER) stress and an unfolded protein response (UPR). However, in an iliac crest biopsy, the COL10A1 p.Y632X mutation was found to produce instability of the mutant mRNA such that little mutant protein may be produced. | Carbamazepine reduces disease severity in a mouse model of metaphyseal chondrodysplasia type Schmid caused by a premature stop codon (Y632X) in the Col10a1 gene.
Forouhan M, Sonntag S, Boot-Handford RP., Free PMC Article | 05/11/2019 |
| biomarkers suitable for the assessment of chronological ageing were identified, and extrapolated to the context of photo-damaged skin. In particular, KANK4, ACAN, Col XI alpha1, and PSG1, were expressed at an increased level in both chronologically-aged and photo-damaged skin. | Genome-wide profiling of adult human papillary and reticular fibroblasts identifies ACAN, Col XI α1, and PSG1 as general biomarkers of dermis ageing, and KANK4 as an exemplary effector of papillary fibroblast ageing, related to contractility.
Haydont V, Neiveyans V, Zucchi H, Fortunel NO, Asselineau D. | 04/27/2019 |
| Plasma samples from lung cancer patients and healthy heavy-smokers controls were tested for levels of COL11A1 and COL10A1 (n = 57 each) and SPARC (n = 90 each). Higher plasma levels of COL10A1 were detected in patients (p </= 0.001), a difference that was driven specifically by females (p < 0.001). No difference in COL11A1 levels between patients and controls was found | Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer.
Andriani F, Landoni E, Mensah M, Facchinetti F, Miceli R, Tagliabue E, Giussani M, Callari M, De Cecco L, Colombo MP, Roz L, Pastorino U, Sozzi G., Free PMC Article | 11/10/2018 |