| An alcohol dehydrogenase 7 gene polymorphism associates with both acute and chronic pain in sickle cell disease. | An alcohol dehydrogenase 7 gene polymorphism associates with both acute and chronic pain in sickle cell disease.
Kashyap Y, He Y, Sadhu N, Yao Y, Wilkie DJ, Molokie RE, Wang ZJ., | 10/4/2023 |
| Association of ADH7 Gene Polymorphism with Schizophrenia in the Han Population of Northern China: a Case-Control Study. | Association of ADH7 Gene Polymorphism with Schizophrenia in the Han Population of Northern China: a Case-Control Study.
Zeng K, Li Y, Gao M, Liu YP, Xu FL, Xia X, Yao J, Wang BJ. | 07/31/2021 |
| These results provide evidence that PAX6 might drive corneal epithelial differentiation by direct or indirect control of retinoic acid signaling processes through ADH7 and ALDH1A1. | Expression of retinoic acid signaling components ADH7 and ALDH1A1 is reduced in aniridia limbal epithelial cells and a siRNA primary cell based aniridia model.
Latta L, Nordström K, Stachon T, Langenbucher A, Fries FN, Szentmáry N, Seitz B, Käsmann-Kellner B. | 04/20/2019 |
| The results of the study do not support our hypothesis that ADH1B and ADH7 genotypes affect blood ethanol, and acetaldehyde concentration. | Effect of alcohol dehydrogenase-1B and -7 polymorphisms on blood ethanol and acetaldehyde concentrations in healthy subjects with a history of moderate alcohol consumption.
Pastorino R, Iuliano L, Vecchioni A, Arzani D, Milic M, Annunziata F, Zerbinati C, Capoluongo E, Bonassi S, McKay JD, Boccia S. | 10/6/2018 |
| These results suggest that variants near ADH7 may play a role in protection from alcohol dependence in this Mexican American cohort. | Protective variant associated with alcohol dependence in a Mexican American cohort.
Norden-Krichmar TM, Gizer IR, Wilhelmsen KC, Schork NJ, Ehlers CL., Free PMC Article | 04/11/2015 |
| ADH1B-ADH1C-ADH7 cluster SNPs confer susceptibility to esophageal squamous cell carcinoma | Replication study of ESCC susceptibility genetic polymorphisms locating in the ADH1B-ADH1C-ADH7 cluster identified by GWAS.
Wang J, Wei J, Xu X, Pan W, Ge Y, Zhou C, Liu C, Gao J, Yang M, Mao W., Free PMC Article | 01/17/2015 |
| Transcriptional regulatory elements of ADH7 were identified that effect gene expression. | Single-nucleotide polymorphisms interact to affect ADH7 transcription.
Jairam S, Edenberg HJ., Free PMC Article | 12/20/2014 |
| common ADH1-7 variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans. | Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism.
Zuo L, Wang K, Zhang XY, Pan X, Wang G, Tan Y, Zhong C, Krystal JH, State M, Zhang H, Luo X., Free PMC Article | 08/31/2013 |
| The rs1573496 (ADH7) polymorphism was not associated with colorectal cancer risk overall in Western-European populations. However, the relationship between alcohol and colorectal cancer risk might be modulated by the rs1573496 (ADH7) polymorphism. | Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphisms, alcohol intake and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study.
Ferrari P, McKay JD, Jenab M, Brennan P, Canzian F, Vogel U, Tjønneland A, Overvad K, Tolstrup JS, Boutron-Ruault MC, Clavel-Chapelon F, Morois S, Kaaks R, Boeing H, Bergmann M, Trichopoulou A, Katsoulis M, Trichopoulos D, Krogh V, Panico S, Sacerdote C, Palli D, Tumino R, Peeters PH, van Gils CH, Bueno-de-Mesquita B, Vrieling A, Lund E, Hjartåker A, Agudo A, Suarez LR, Arriola L, Chirlaque MD, Ardanaz E, Sánchez MJ, Manjer J, Lindkvist B, Hallmans G, Palmqvist R, Allen N, Key T, Khaw KT, Slimani N, Rinaldi S, Romieu I, Boffetta P, Romaguera D, Norat T, Riboli E. | 05/11/2013 |
| The current results support the ADH7 A92G SNP as a marker for the risk of SCCHN in non-Hispanic white populations. | A single nucleotide polymorphism in the alcohol dehydrogenase 7 gene (alanine to glycine substitution at amino acid 92) is associated with the risk of squamous cell carcinoma of the head and neck.
Wei S, Liu Z, Zhao H, Niu J, Wang LE, El-Naggar AK, Sturgis EM, Wei Q, Wei S, Liu Z, Zhao H, Niu J, Wang LE, El-Naggar AK, Sturgis EM, Wei Q., Free PMC Articles: PMC2891145, PMC2891145 | 07/26/2010 |
| An association between age at onset of regular alcohol use and a SNP just upstream of ADH7 (rs2654849, p = .003) was observed. | Associations between ADH gene variants and alcohol phenotypes in Dutch adults.
van Beek JH, Willemsen G, de Moor MH, Hottenga JJ, Boomsma DI. | 06/14/2010 |
| ADH7 gene polymorphisms are associated with upper aerodigestive tract cancers. | Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a Japanese population.
Oze I, Matsuo K, Suzuki T, Kawase T, Watanabe M, Hiraki A, Ito H, Hosono S, Ozawa T, Hatooka S, Yatabe Y, Hasegawa Y, Shinoda M, Kiura K, Tajima K, Tanimoto M, Tanaka H, Oze I, Matsuo K, Suzuki T, Kawase T, Watanabe M, Hiraki A, Ito H, Hosono S, Ozawa T, Hatooka S, Yatabe Y, Hasegawa Y, Shinoda M, Kiura K, Tajima K, Tanimoto M, Tanaka H. | 02/1/2010 |
| Alleles of ADH7 SNPs were associated with the early stages of alcohol metabolism, with additional effects in the ADH1A, ADH1B and ADH4 regions. | ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.
Birley AJ, James MR, Dickson PA, Montgomery GW, Heath AC, Martin NG, Whitfield JB, Birley AJ, James MR, Dickson PA, Montgomery GW, Heath AC, Martin NG, Whitfield JB., Free PMC Articles: PMC2664151, PMC2664151 | 01/21/2010 |
| Changes in the activity of class IV ADH in the sera of patients with gastric cancer seems to be caused by release of the isoenzyme from cancer cells. | Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with gastric cancer.
Jelski W, Chrostek L, Zalewski B, Szmitkowski M. | 01/21/2010 |
| Single Nucleotide Polymorphism in ADH7 gene is associated with upper aerodigestive cancer. | Multiple ADH genes are associated with upper aerodigestive cancers.
Hashibe M, McKay JD, Curado MP, Oliveira JC, Koifman S, Koifman R, Zaridze D, Shangina O, Wünsch-Filho V, Eluf-Neto J, Levi JE, Matos E, Lagiou P, Lagiou A, Benhamou S, Bouchardy C, Szeszenia-Dabrowska N, Menezes A, Dall'Agnol MM, Merletti F, Richiardi L, Fernandez L, Lence J, Talamini R, Barzan L, Mates D, Mates IN, Kjaerheim K, Macfarlane GJ, Macfarlane TV, Simonato L, Canova C, Holcátová I, Agudo A, Castellsagué X, Lowry R, Janout V, Kollarova H, Conway DI, McKinney PA, Znaor A, Fabianova E, Bencko V, Lissowska J, Chabrier A, Hung RJ, Gaborieau V, Boffetta P, Brennan P, Hashibe M, McKay JD, Curado MP, Oliveira JC, Koifman S, Koifman R, Zaridze D, Shangina O, Wünsch-Filho V, Eluf-Neto J, Levi JE, Matos E, Lagiou P, Lagiou A, Benhamou S, Bouchardy C, Szeszenia-Dabrowska N, Menezes A, Dall'Agnol MM, Merletti F, Richiardi L, Fernandez L, Lence J, Talamini R, Barzan L, Mates D, Mates IN, Kjaerheim K, Macfarlane GJ, Macfarlane TV, Simonato L, Canova C, Holcátová I, Agudo A, Castellsagué X, Lowry R, Janout V, Kollarova H, Conway DI, McKinney PA, Znaor A, Fabianova E, Bencko V, Lissowska J, Chabrier A, Hung RJ, Gaborieau V, Boffetta P, Brennan P. | 01/21/2010 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | See all PubMed (3) articlesThe association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population.
Husemoen LL, Jørgensen T, Borch-Johnsen K, Hansen T, Pedersen O, Linneberg A. Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a Japanese population.
Oze I, Matsuo K, Suzuki T, Kawase T, Watanabe M, Hiraki A, Ito H, Hosono S, Ozawa T, Hatooka S, Yatabe Y, Hasegawa Y, Shinoda M, Kiura K, Tajima K, Tanimoto M, Tanaka H, Oze I, Matsuo K, Suzuki T, Kawase T, Watanabe M, Hiraki A, Ito H, Hosono S, Ozawa T, Hatooka S, Yatabe Y, Hasegawa Y, Shinoda M, Kiura K, Tajima K, Tanimoto M, Tanaka H. Multiple ADH genes are associated with upper aerodigestive cancers.
Hashibe M, McKay JD, Curado MP, Oliveira JC, Koifman S, Koifman R, Zaridze D, Shangina O, Wünsch-Filho V, Eluf-Neto J, Levi JE, Matos E, Lagiou P, Lagiou A, Benhamou S, Bouchardy C, Szeszenia-Dabrowska N, Menezes A, Dall'Agnol MM, Merletti F, Richiardi L, Fernandez L, Lence J, Talamini R, Barzan L, Mates D, Mates IN, Kjaerheim K, Macfarlane GJ, Macfarlane TV, Simonato L, Canova C, Holcátová I, Agudo A, Castellsagué X, Lowry R, Janout V, Kollarova H, Conway DI, McKinney PA, Znaor A, Fabianova E, Bencko V, Lissowska J, Chabrier A, Hung RJ, Gaborieau V, Boffetta P, Brennan P, Hashibe M, McKay JD, Curado MP, Oliveira JC, Koifman S, Koifman R, Zaridze D, Shangina O, Wünsch-Filho V, Eluf-Neto J, Levi JE, Matos E, Lagiou P, Lagiou A, Benhamou S, Bouchardy C, Szeszenia-Dabrowska N, Menezes A, Dall'Agnol MM, Merletti F, Richiardi L, Fernandez L, Lence J, Talamini R, Barzan L, Mates D, Mates IN, Kjaerheim K, Macfarlane GJ, Macfarlane TV, Simonato L, Canova C, Holcátová I, Agudo A, Castellsagué X, Lowry R, Janout V, Kollarova H, Conway DI, McKinney PA, Znaor A, Fabianova E, Bencko V, Lissowska J, Chabrier A, Hung RJ, Gaborieau V, Boffetta P, Brennan P. | 06/4/2008 |
| the ADH7 variation may contribute to the genetic component of variation in personality traits, with the risk for SD and personality traits being partially shared. | ADH7 variation modulates extraversion and conscientiousness in substance-dependent subjects.
Luo X, Kranzler HR, Zuo L, Zhang H, Wang S, Gelernter J, Luo X, Kranzler HR, Zuo L, Zhang H, Wang S, Gelernter J., Free PMC Articles: PMC3160628, PMC3160628 | 01/21/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | [Association analysis of gene polymorphism in alcohol metabolizing enzymes with risk for coronary atherosclerosis].
Marusin AV, Stepanov VA, Spiridonova MG, Khar'kov VA, Pel's IaR, Puzyrev VP. | 03/13/2008 |
| Observational study of genotype prevalence. (HuGE Navigator) | Identification of new single nucleotid polymorphisms (SNP) in alcohol dehydrogenase class IV ADH7 gene within a French population.
Abbas A, Lechevrel M, Sichel F. | 03/13/2008 |
| Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) | [Alcohol dehydrogenases ADH1B and ADH7 gene polymorphism in Russian population from the Siberian region].
Marusin AV, Stepanov VA, Spiridonova MG, Puzyrev VP. | 03/13/2008 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (12) articlesInvestigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.
Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A. A single nucleotide polymorphism in the alcohol dehydrogenase 7 gene (alanine to glycine substitution at amino acid 92) is associated with the risk of squamous cell carcinoma of the head and neck.
Wei S, Liu Z, Zhao H, Niu J, Wang LE, El-Naggar AK, Sturgis EM, Wei Q, Wei S, Liu Z, Zhao H, Niu J, Wang LE, El-Naggar AK, Sturgis EM, Wei Q. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.
Ross CJ, Katzov-Eckert H, Dubé MP, Brooks B, Rassekh SR, Barhdadi A, Feroz-Zada Y, Visscher H, Brown AM, Rieder MJ, Rogers PC, Phillips MS, Carleton BC, Hayden MR, CPNDS Consortium. Genetical genomic determinants of alcohol consumption in rats and humans.
Tabakoff B, Saba L, Printz M, Flodman P, Hodgkinson C, Goldman D, Koob G, Richardson HN, Kechris K, Bell RL, Hübner N, Heinig M, Pravenec M, Mangion J, Legault L, Dongier M, Conigrave KM, Whitfield JB, Saunders J, Grant B, Hoffman PL, WHO/ISBRA Study on State and Trait Markers of Alcoholism. A non-synonymous variant in ADH1B is strongly associated with prenatal alcohol use in a European sample of pregnant women.
Zuccolo L, Fitz-Simon N, Gray R, Ring SM, Sayal K, Smith GD, Lewis SJ. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.
Saito A, Kawamoto M, Kamatani N. ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.
Birley AJ, James MR, Dickson PA, Montgomery GW, Heath AC, Martin NG, Whitfield JB, Birley AJ, James MR, Dickson PA, Montgomery GW, Heath AC, Martin NG, Whitfield JB. Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.
Kuo PH, Kalsi G, Prescott CA, Hodgkinson CA, Goldman D, van den Oord EJ, Alexander J, Jiang C, Sullivan PF, Patterson DG, Walsh D, Kendler KS, Riley BP. ADH7 variation modulates extraversion and conscientiousness in substance-dependent subjects.
Luo X, Kranzler HR, Zuo L, Zhang H, Wang S, Gelernter J, Luo X, Kranzler HR, Zuo L, Zhang H, Wang S, Gelernter J. Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans.
Luo X, Kranzler HR, Zuo L, Wang S, Schork NJ, Gelernter J. Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence.
Luo X, Kranzler HR, Zuo L, Wang S, Schork NJ, Gelernter J. Frequencies of single nucleotide polymorphism in alcohol dehydrogenase7 gene in patients with multiple system atrophy and controls.
Kim HS, Lee MS. | 03/13/2008 |
| A recombinational hotspot within intron 7 of the ADH7 gene were seen using 25 SNPs; haplotypes associated with inter-individual variation in the early stages of alcohol metabolism were identified. | Association of the gastric alcohol dehydrogenase gene ADH7 with variation in alcohol metabolism.
Birley AJ, James MR, Dickson PA, Montgomery GW, Heath AC, Whitfield JB, Martin NG. | 01/21/2010 |