| Sarcolemma wounding activates dynamin-dependent endocytosis in striated muscle. | Sarcolemma wounding activates dynamin-dependent endocytosis in striated muscle.
McDade JR, Naylor MT, Michele DE., Free PMC Article | 06/19/2021 |
| Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR-132/MeCP2 pathway. | Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR-132/MeCP2 pathway.
Xie AJ, Hou TY, Xiong W, Huang HZ, Zheng J, Li K, Man HY, Hu YZ, Han ZT, Zhang HH, Wei N, Wang JZ, Liu D, Lu Y, Zhu LQ., Free PMC Article | 09/19/2020 |
| The present work with dyn1-KO mice further confirms that Ca(2+)-dependent transmitter release is mainly via subquantal mode, suggesting that subquantal release could be also important in other types of cells | Dynamin 1 Restrains Vesicular Release to a Subquantal Mode In Mammalian Adrenal Chromaffin Cells.
Wu Q, Zhang Q, Liu B, Li Y, Wu X, Kuo S, Zheng L, Wang C, Zhu F, Zhou Z., Free PMC Article | 10/19/2019 |
| Cellular fluorescein hyperfluorescence is dynamin-dependent. | Cellular fluorescein hyperfluorescence is dynamin-dependent and increased by Tetronic 1107 treatment.
Khan TF, Price BL, Morgan PB, Maldonado-Codina C, Dobson CB. | 03/30/2019 |
| dynamin is a molecular motor which would be involved in GLUT4 translocation by facilitating exocytosis | A multiscale study of the role of dynamin in the regulation of glucose uptake.
Trouillon R, Letizia MC, Menzies KJ, Mouchiroud L, Auwerx J, Schoonjans K, Gijs MAM. | 06/23/2018 |
| reveal functional differences between Dnm1a and Dnm1b isoforms in the presence of a challenge, i.e. toxic Dnm1(Ftfl), while reinforcing its effect explicitly in this model of severe pediatric epilepsy | Dynamin 1 isoform roles in a mouse model of severe childhood epileptic encephalopathy.
Asinof S, Mahaffey C, Beyer B, Frankel WN, Boumil R., Free PMC Article | 03/3/2018 |
| in the mature epididymis, predominantly localized in clear cells of the distal segments | Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis.
Zhou W, De Iuliis GN, Turner AP, Reid AT, Anderson AL, McCluskey A, McLaughlin EA, Nixon B. | 12/2/2017 |
| Dynamin may facilitate Fas-mediated apoptotic death in the brain, and Hsp70 may protect by preventing this trafficking. | 70-kDa Heat Shock Protein Downregulates Dynamin in Experimental Stroke: A New Therapeutic Target?
Kim JY, Kim N, Zheng Z, Lee JE, Yenari MA., Free PMC Article | 05/20/2017 |
| These results suggested that dynamin 1 was susceptible to the aging process, and that a reduction in dynamin 1 may result in hippocampaldependent memory deficits by disrupting endocytosis and the release of neurotransmitters. | Reduction of dynamin 1 in the hippocampus of aged mice is associated with the decline in hippocampal‑dependent memory.
Yoo DY, Jung HY, Kim JW, Yim HS, Kim DW, Nam H, Suh JG, Choi JH, Won MH, Yoon YS, Hwang IK. | 04/8/2017 |
| Tissue-specific dynamin-1 deletion at the calyx of Held decreases short-term depression through a mechanism distinct from vesicle resupply. | Tissue-specific dynamin-1 deletion at the calyx of Held decreases short-term depression through a mechanism distinct from vesicle resupply.
Mahapatra S, Fan F, Lou X., Free PMC Article | 12/24/2016 |
| findings support a role for HTT on dynamin 1 function and ER homoeostasis. Proteolysis-induced alteration of this function may be relevant to disease. | Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation.
El-Daher MT, Hangen E, Bruyère J, Poizat G, Al-Ramahi I, Pardo R, Bourg N, Souquere S, Mayet C, Pierron G, Lévêque-Fort S, Botas J, Humbert S, Saudou F., Free PMC Article | 11/28/2015 |
| the identification of the oligomerization cycle of dynamin is an attractive potential therapeutic target to treat chronic kidney diseases . | Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.
Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S., Free PMC Article | 09/5/2015 |
| In the developing neurons, there is a dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis. | A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.
Wu Y, O'Toole ET, Girard M, Ritter B, Messa M, Liu X, McPherson PS, Ferguson SM, De Camilli P., Free PMC Article | 05/16/2015 |
| Using an inducible knockout mouse model to generate dynamin 1- and 2-deficient primary osteoclast precursors and myoblasts, it was shown that fusion of both cell types requires dynamin. | Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts.
Shin NY, Choi H, Neff L, Wu Y, Saito H, Ferguson SM, De Camilli P, Baron R., Free PMC Article | 02/28/2015 |
| Dynamin 1 is required for memory formation. | Dynamin 1 is required for memory formation.
Fà M, Staniszewski A, Saeed F, Francis YI, Arancio O., Free PMC Article | 01/3/2015 |
| As low-level expression of the dynamin 3 gene in these cells could not be excluded, we have now engineered dynamin 1, 2 and 3 triple KO (TKO) fibroblasts. | Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors.
Park RJ, Shen H, Liu L, Liu X, Ferguson SM, De Camilli P., Free PMC Article | 06/21/2014 |
| Results further implicate dynamin-1 in vesicular protein transport processes relevant to synaptic and post-Golgi pathways and indicate a possible role in photoreceptor stability | Protein partners of dynamin-1 in the retina.
Grossman GH, Ebke LA, Beight CD, Jang GF, Crabb JW, Hagstrom SA., Free PMC Article | 04/26/2014 |
| Data indicate that coxsackievirus and adenovirus receptor (CAR) internalization was lipid microdomain-, actin-, and dynamin-dependent, and subsequently followed by CAR degradation in lysosomes. | Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting.
Salinas S, Zussy C, Loustalot F, Henaff D, Menendez G, Morton PE, Parsons M, Schiavo G, Kremer EJ., Free PMC Article | 04/12/2014 |
| A missense mutation of dynamin 1 inhibits endocytosis via clathrin-mediated endocytosis. | Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.
Neef J, Jung S, Wong AB, Reuter K, Pangrsic T, Chakrabarti R, Kügler S, Lenz C, Nouvian R, Boumil RM, Frankel WN, Wichmann C, Moser T., Free PMC Article | 03/15/2014 |
| Data indicate that dynamin, clathrin, adaptor protein complex-2 (AP2), and amphiphysin contribute to the depolarization-evoked entry in endocytosis. | Molecular components required for resting and stimulated endocytosis of botulinum neurotoxins by glutamatergic and peptidergic neurons.
Meng J, Wang J, Lawrence GW, Dolly JO. | 12/21/2013 |
| Data show that dynamin 1 and dynamin 2 GTPases localize to the developing acrosome of maturing germ cells. | Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa.
Reid AT, Lord T, Stanger SJ, Roman SD, McCluskey A, Robinson PJ, Aitken RJ, Nixon B., Free PMC Article | 01/26/2013 |
| S857 phosphorylation of dynamin 1 is modulated by neuronal activity in nerve terminals. | Activity-dependent phosphorylation of dynamin 1 at serine 857.
Xie W, Adayev T, Zhu H, Wegiel J, Wieraszko A, Hwang YW. | 01/12/2013 |
| Analysis of cysteine string protein alpha (CSPalpha)-dynamin 1 interactions reveals unexpectedly that CSPalpha regulates the polymerization of dynamin 1 in mouse hippocampal cell cultures. | Identification of CSPα clients reveals a role in dynamin 1 regulation.
Zhang YQ, Henderson MX, Colangelo CM, Ginsberg SD, Bruce C, Wu T, Chandra SS., Free PMC Article | 06/23/2012 |
| These findings reveal a mechanism aimed at preventing synaptic transmission failure due to vesicle depletion when recycling vesicle traffic is backed up by a defect in dynamin-dependent endocytosis. | Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses.
Lou X, Fan F, Messa M, Raimondi A, Wu Y, Looger LL, Ferguson SM, De Camilli P., Free PMC Article | 04/14/2012 |
| Caveolin-1 regulation of dynamin-dependent, raft-mediated endocytosis of cholera toxin-B subunit occurs independently of caveolae | Caveolin-1 regulation of dynamin-dependent, raft-mediated endocytosis of cholera toxin-B sub-unit occurs independently of caveolae.
Lajoie P, Kojic LD, Nim S, Li L, Dennis JW, Nabi IR., Free PMC Article | 12/24/2011 |