| Alzheimer's disease/dementia-associated brain pathology in aging DPP6-KO mice. | Alzheimer's disease/dementia-associated brain pathology in aging DPP6-KO mice.
Lin L, Petralia RS, Holtzclaw L, Wang YX, Abebe D, Hoffman DA., Free PMC Article | 11/5/2022 |
| expression pattern of DPP6 suggests that it may be involved in mandible and tooth development. | Expression of DPP6 in Meckel's cartilage and tooth germs during mouse facial development.
Du J, Fan Z, Ma X, Wu Y, Liu S, Gao Y, Shen Y, Fan M, Wang S. | 09/13/2014 |
| Dipeptidyl-peptidase 6 has an unexpected but important role in cell adhesion and motility, impacting the hippocampal synaptic development and function. | DPP6 regulation of dendritic morphogenesis impacts hippocampal synaptic development.
Lin L, Sun W, Throesch B, Kung F, Decoster JT, Berner CJ, Cheney RE, Rudy B, Hoffman DA., Free PMC Article | 03/1/2014 |
| WT PrP(C), in a DPP6-dependent manner, modulated Kv4.2 channel properties, causing an increase in peak amplitude | The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6.
Mercer RC, Ma L, Watts JC, Strome R, Wohlgemuth S, Yang J, Cashman NR, Coulthart MB, Schmitt-Ulms G, Jhamandas JH, Westaway D., Free PMC Article | 02/22/2014 |
| Findings of this study indicate that an altered response of Kv4/DPP6 to long-term neuroleptic administration is involved in neuroleptic-induced TD. | DPP6 as a candidate gene for neuroleptic-induced tardive dyskinesia.
Tanaka S, Syu A, Ishiguro H, Inada T, Horiuchi Y, Ishikawa M, Koga M, Noguchi E, Ozaki N, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T. | 10/26/2013 |
| DPP6 co-expression with TASK-3 results in the formation of a protein complex that enhances resting membrane potassium conductance. | A new TASK for Dipeptidyl Peptidase-like Protein 6.
Nadin BM, Pfaffinger PJ., Free PMC Article | 10/26/2013 |
| the present study described epigenetic silencing of Dpp6 expression by DNA methylation and established that its ectopic expression can act as negative signal during RA induced neuronal differentiation of P19 cells. | Epigenetic regulation of Dpp6 expression by Dnmt3b and its novel role in the inhibition of RA induced neuronal differentiation of P19 cells.
Sheikh MA, Malik YS, Yu H, Lai M, Wang X, Zhu X., Free PMC Article | 08/10/2013 |
| In the presence of DPP6 or DPP10, cell surface Kv4.2 protein expression is selectively increased. | Augmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilization.
Foeger NC, Norris AJ, Wren LM, Nerbonne JM., Free PMC Article | 06/16/2012 |
| The expression pattern of Dpp6 suggests that Dpp6 may be involved in embryonic craniofacial development. | Expression of Dpp6 in mouse embryonic craniofacial development.
Du J, Fan Z, Ma X, Gao Y, Wu Y, Liu S, Shen Y, Fan M, Wang S. | 02/18/2012 |
| The DPP6-E is selectively expressed in a few neuronal populations in brain including cerebellar granule neurons, hippocampal pyramidal cells and neurons in intermediary layers of the superior colliculus. | A novel DPP6 isoform (DPP6-E) can account for differences between neuronal and reconstituted A-type K(+) channels.
Maffie J, Blenkinsop T, Rudy B., Free PMC Article | 03/11/2011 |
| DPP6 is necessary and sufficient to explain the larger unitary conductance of neuronal Kv4 channels underlying the neuronal subthreshold-operating A-type potassium (K+) current. | The dipeptidyl-peptidase-like protein DPP6 determines the unitary conductance of neuronal Kv4.2 channels.
Kaulin YA, De Santiago-Castillo JA, Rocha CA, Nadal MS, Rudy B, Covarrubias M., Free PMC Article | 01/21/2010 |