| MiRNA-470-5p suppresses epithelial-mesenchymal transition of embryonic palatal shelf epithelial cells by targeting Fgfr1 during palatogenesis. | MiRNA-470-5p suppresses epithelial-mesenchymal transition of embryonic palatal shelf epithelial cells by targeting Fgfr1 during palatogenesis.
Zhou J, Zhang M, Zhang M, Tan M, Ji Y, Shu S, Liang Y., Free PMC Article | 10/24/2023 |
| Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice. | Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice.
Maniou E, Farah F, Marshall AR, Crane-Smith Z, Krstevski A, Stathopoulou A, Greene NDE, Copp AJ, Galea GL., Free PMC Article | 10/11/2023 |
| Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death. | Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death.
Wernlé KK, Sonnenfelt MA, Leek CC, Ganji E, Sullivan AL, Offutt C, Shuff J, Ornitz DM, Killian ML., | 09/7/2023 |
| Fgfr1 deficiency in osteocytes leads to increased bone mass by enhancing Wnt/beta-catenin signaling. | Fgfr1 deficiency in osteocytes leads to increased bone mass by enhancing Wnt/β-catenin signaling.
Tang Y, Yang P, Jin M, Huang S, Chen H, Chen L, Yang J, Su N. | 07/23/2023 |
| FGF21-FGFR1 controls mitochondrial homeostasis in cardiomyocytes by modulating the degradation of OPA1. | FGF21-FGFR1 controls mitochondrial homeostasis in cardiomyocytes by modulating the degradation of OPA1.
Yan B, Mei Z, Tang Y, Song H, Wu H, Jing Q, Zhang X, Yan C, Han Y., Free PMC Article | 05/13/2023 |
| Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1. | Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1.
Coetzee AS, Carter EP, Rodríguez-Fernández L, Heward J, Wang Q, Karim SA, Boughetane L, Milton C, Uyulur F, Morton JP, Kocher HM, Grose RP., Free PMC Article | 02/14/2023 |
| Paracrine interactions through FGFR1 and FGFR2 receptors regulate the development of preimplantation mouse chimaeric embryo. | Paracrine interactions through FGFR1 and FGFR2 receptors regulate the development of preimplantation mouse chimaeric embryo.
Krawczyk K, Wilczak K, Szczepańska K, Maleszewski M, Suwińska A., Free PMC Article | 01/28/2023 |
| Convergent biological pathways underlying the Kallmann syndrome-linked genes Hs6st1 and Fgfr1. | Convergent biological pathways underlying the Kallmann syndrome-linked genes Hs6st1 and Fgfr1.
Moon S, Zhao YT., Free PMC Article | 12/24/2022 |
| TNFAIP3 mediates FGFR1 activation-induced breast cancer angiogenesis by promoting VEGFA expression and secretion. | TNFAIP3 mediates FGFR1 activation-induced breast cancer angiogenesis by promoting VEGFA expression and secretion.
Gao M, Li X, Yang M, Feng W, Lin Y, He T. | 10/22/2022 |
| FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesis. | FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesis.
Zhu X, Qiu C, Wang Y, Jiang Y, Chen Y, Fan L, Ren R, Wang Y, Chen Y, Feng Y, Zhou X, Zhu Y, Ge Z, Lai D, Qin L, Simons M, Yu L., Free PMC Article | 07/2/2022 |
| Immunohistochemical Expression Pattern of FGFR1, FGFR2, RIP5, and HIP2 in Developing and Postnatal Kidneys of Dab1(-/-) (yotari) Mice. | Immunohistochemical Expression Pattern of FGFR1, FGFR2, RIP5, and HIP2 in Developing and Postnatal Kidneys of Dab1(-/-) (yotari) Mice.
Kelam N, Racetin A, Katsuyama Y, Vukojević K, Kostić S., Free PMC Article | 03/19/2022 |
| MiR-21-3p Inhibits Adipose Browning by Targeting FGFR1 and Aggravates Atrial Fibrosis in Diabetes. | MiR-21-3p Inhibits Adipose Browning by Targeting FGFR1 and Aggravates Atrial Fibrosis in Diabetes.
Pan JA, Lin H, Yu JY, Zhang HL, Zhang JF, Wang CQ, Gu J., Free PMC Article | 02/5/2022 |
| FGF20-FGFR1 signaling through MAPK and PI3K controls sensory progenitor differentiation in the organ of Corti. | FGF20-FGFR1 signaling through MAPK and PI3K controls sensory progenitor differentiation in the organ of Corti.
Su Y, Yang LM, Ornitz DM., Free PMC Article | 01/22/2022 |
| PPARalpha agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1. | PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
Xu Y, Denning KL, Lu Y., Free PMC Article | 11/22/2021 |
| Oligodendrocyte-Specific Deletion of FGFR1 Reduces Cerebellar Inflammation and Neurodegeneration in MOG35-55-Induced EAE. | Oligodendrocyte-Specific Deletion of FGFR1 Reduces Cerebellar Inflammation and Neurodegeneration in MOG(35-55)-Induced EAE.
Rajendran R, Rajendran V, Giraldo-Velasquez M, Megalofonou FF, Gurski F, Stadelmann C, Karnati S, Berghoff M., Free PMC Article | 10/30/2021 |
| Conditional Fgfr1 Deletion in GnRH Neurons Leads to Minor Disruptions in the Reproductive Axis of Male and Female Mice. | Conditional Fgfr1 Deletion in GnRH Neurons Leads to Minor Disruptions in the Reproductive Axis of Male and Female Mice.
Dela Cruz C, Horton CA, Sanders KN, Andersen ND, Tsai PS., Free PMC Article | 06/5/2021 |
| Endothelial FGFR1 (Fibroblast Growth Factor Receptor 1) Deficiency Contributes Differential Fibrogenic Effects in Kidney and Heart of Diabetic Mice. | Endothelial FGFR1 (Fibroblast Growth Factor Receptor 1) Deficiency Contributes Differential Fibrogenic Effects in Kidney and Heart of Diabetic Mice.
Li J, Liu H, Srivastava SP, Hu Q, Gao R, Li S, Kitada M, Wu G, Koya D, Kanasaki K. | 05/8/2021 |
| Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes. | Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes.
Meyer M, Ben-Yehuda Greenwald M, Rauschendorfer T, Sänger C, Jukic M, Iizuka H, Kubo F, Chen L, Ornitz DM, Werner S., Free PMC Article | 04/24/2021 |
| Expression of fibroblast growth factor receptor1, -2c, and -3c transcripts in mouse molars after tooth eruption. | Expression of fibroblast growth factor receptor1, -2c, and -3c transcripts in mouse molars after tooth eruption.
Kano T, Morita T, Sumida K, Yumoto H, Baba O. | 04/17/2021 |
| FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 Mice. | FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 Mice.
Ferone G, Song JY, Krijgsman O, van der Vliet J, Cozijnsen M, Semenova EA, Adams DJ, Peeper D, Berns A., Free PMC Article | 03/27/2021 |
| LRTM1 promotes the differentiation of myoblast cells by negatively regulating the FGFR1 signaling pathway. | LRTM1 promotes the differentiation of myoblast cells by negatively regulating the FGFR1 signaling pathway.
Li HK, Zhou Y, Ding J, Xiong L, Shi YX, He YJ, Yang D, Deng ZL, Nie M, Fei Gao Y. | 03/13/2021 |
| DC-SCRIPT affects mammary organoids branching morphogenesis by modulating the FGFR1-pERK signaling axis. | DC-SCRIPT affects mammary organoids branching morphogenesis by modulating the FGFR1-pERK signaling axis.
Tang C, van den Bijgaart RJE, Looman MWG, Triantis V, Nørskov Søndergaard J, Ansems M, Adema GJ. | 01/23/2021 |
| Osteocyte Death and Bone Overgrowth in Mice Lacking Fibroblast Growth Factor Receptors 1 and 2 in Mature Osteoblasts and Osteocytes. | Osteocyte Death and Bone Overgrowth in Mice Lacking Fibroblast Growth Factor Receptors 1 and 2 in Mature Osteoblasts and Osteocytes.
McKenzie J, Smith C, Karuppaiah K, Langberg J, Silva MJ, Ornitz DM., Free PMC Article | 09/26/2020 |
| regulation of fibroblast growth factor receptor 1 trafficking and function by extracellular galectins | Differential regulation of fibroblast growth factor receptor 1 trafficking and function by extracellular galectins.
Kucińska M, Porębska N, Lampart A, Latko M, Knapik A, Zakrzewska M, Otlewski J, Opaliński Ł., Free PMC Article | 06/20/2020 |
| Authors have deleted the STK domain and mutated the critical Y177 residue and demonstrate that the transforming activity of these mutated genes is reduced compared to the BCR-FGFR1 parental kinase. In addition, we demonstrate that deletion of the FGFR1 tyrosine kinase domain abrogates transforming ability, which is not compensated for by BCR STK activity. | Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome.
Chong Y, Liu Y, Lu S, Cai B, Qin H, Chang CS, Ren M, Cowell JK, Hu T. | 05/23/2020 |