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    Fn1 fibronectin 1 [ Mus musculus (house mouse) ]

    Gene ID: 14268, updated on 21-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    LncRNA ADAMTS9-AS2 regulates periodontal ligament cell migration under mechanical compression via ADAMTS9/fibronectin.

    LncRNA ADAMTS9-AS2 regulates periodontal ligament cell migration under mechanical compression via ADAMTS9/fibronectin.
    Yu Q, Guo K, Yang Y, Liu H, Huang Y, Li W.

    02/15/2024
    Matrix stiffness controls megakaryocyte adhesion, fibronectin fibrillogenesis, and proplatelet formation through Itgbeta3.

    Matrix stiffness controls megakaryocyte adhesion, fibronectin fibrillogenesis, and proplatelet formation through Itgβ3.
    Guinard I, Nguyen T, Brassard-Jollive N, Weber J, Ruch L, Reininger L, Brouard N, Eckly A, Collin D, Lanza F, Léon C., Free PMC Article

    10/30/2023
    Unravelling the role of immune cells and FN1 in the recurrence and therapeutic process of skull base chordoma.

    Unravelling the role of immune cells and FN1 in the recurrence and therapeutic process of skull base chordoma.
    Huo X, Ma S, Wang C, Song L, Yao B, Zhu S, Li P, Wang L, Wu Z, Wang K., Free PMC Article

    10/4/2023
    Nucleation of fibronectin fibril assembly requires binding between heparin and the 13th type III module of fibronectin.

    Nucleation of fibronectin fibril assembly requires binding between heparin and the 13th type III module of fibronectin.
    Lovett BM, Hill KE, Randolph EM, Wang L, Schwarzbauer JE., Free PMC Article

    06/1/2023
    Fibronectin-LILRB4/gp49B interaction negatively regulates osteoclastogenesis through inhibition of RANKL-induced TRAF6/TAK1/NF-kB/MAPK signaling.

    Fibronectin-LILRB4/gp49B interaction negatively regulates osteoclastogenesis through inhibition of RANKL-induced TRAF6/TAK1/NF-kB/MAPK signaling.
    Su MT, Ono K, Kezuka D, Miyamoto S, Mori Y, Takai T.

    03/16/2023
    LILRB4/gp49B Co-Localizes with Integrin via Fibronectin at Focal Adhesion Sites on Mast Cells.

    LILRB4/gp49B Co-Localizes with Integrin via Fibronectin at Focal Adhesion Sites on Mast Cells.
    Miyamoto S, Chiba T, Itoi S, Su MT, Takai T.

    03/15/2023
    PDGFRbeta-positive cell-mediated post-stroke remodeling of fibronectin and laminin alpha2 for tissue repair and functional recovery.

    PDGFRβ-positive cell-mediated post-stroke remodeling of fibronectin and laminin α2 for tissue repair and functional recovery.
    Shibahara T, Nakamura K, Wakisaka Y, Shijo M, Yamanaka K, Takashima M, Takaki H, Hidaka M, Kitazono T, Ago T., Free PMC Article

    03/11/2023
    Infiltrating CD8+ T cells and M2 macrophages are retained in tumor matrix tracks enriched in low tension fibronectin fibers.

    Infiltrating CD8+ T cells and M2 macrophages are retained in tumor matrix tracks enriched in low tension fibronectin fibers.
    Fonta CM, Loustau T, Li C, Poilil Surendran S, Hansen U, Murdamoothoo D, Benn MC, Velazquez-Quesada I, Carapito R, Orend G, Vogel V.

    02/26/2023
    Plasma fibronectin can affect the cytokine profile and monocytes/macrophages function in addition to predicting the prognosis of advanced sepsis.

    Plasma fibronectin can affect the cytokine profile and monocytes/macrophages function in addition to predicting the prognosis of advanced sepsis.
    Yuan X, Wu Y, Lin J, Weng Q, Wu L, Yang S, Li X, Tan M, Lin Z, Lian X, Chen Y.

    03/5/2022
    Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome.

    Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome.
    Mao M, Popli T, Jeanne M, Hoff K, Sen S, Gould DB., Free PMC Article

    02/5/2022
    Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.

    Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
    Wu Y, Qi Y, Qiu Z, Chen W.

    01/8/2022
    Periostin and matrix stiffness combine to regulate myofibroblast differentiation and fibronectin synthesis during palatal healing.

    Periostin and matrix stiffness combine to regulate myofibroblast differentiation and fibronectin synthesis during palatal healing.
    Nikoloudaki G, Snider P, Simmons O, Conway SJ, Hamilton DW., Free PMC Article

    10/23/2021
    Fibronectin has multifunctional roles in posterior capsular opacification (PCO).

    Fibronectin has multifunctional roles in posterior capsular opacification (PCO).
    Shihan MH, Kanwar M, Wang Y, Jackson EE, Faranda AP, Duncan MK., Free PMC Article

    05/29/2021
    Adhesion to fibronectin via alpha5beta1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis.

    Adhesion to fibronectin via α5β1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis.
    Matsuura S, Thompson CR, Ng SK, Ward CM, Karagianni A, Mazzeo C, Malara A, Balduini A, Ravid K., Free PMC Article

    02/20/2021
    Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling.

    Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling.
    Roberts AL, Mavlyutov TA, Perlmutter TE, Curry SM, Harris SL, Chauhan AK, McDowell CM., Free PMC Article

    12/12/2020
    A scaffold for signaling of Tim-4-mediated efferocytosis is formed by fibronectin.

    A scaffold for signaling of Tim-4-mediated efferocytosis is formed by fibronectin.
    Lee J, Park B, Moon B, Park J, Moon H, Kim K, Lee SA, Kim D, Min C, Lee DH, Lee G, Park D., Free PMC Article

    09/5/2020
    These studies show that Fn1 plays an important role in the adaptation of podocytes to mechanical stress.

    Fibronectin is up-regulated in podocytes by mechanical stress.
    Kliewe F, Kaling S, Lötzsch H, Artelt N, Schindler M, Rogge H, Schröder S, Scharf C, Amann K, Daniel C, Lindenmeyer MT, Cohen CD, Endlich K, Endlich N.

    06/13/2020
    Phosphorylated fibronectin enhances cell attachment and upregulates mechanical cell functions.

    Phosphorylated fibronectin enhances cell attachment and upregulates mechanical cell functions.
    Yalak G, Shiu JY, Schoen I, Mitsi M, Vogel V., Free PMC Article

    02/22/2020
    Circulating tumor cells demonstrate enhanced migration in part through fibronectin regulation of integrin B1 and SLUG.

    Fibronectin Regulation of Integrin B1 and SLUG in Circulating Tumor Cells.
    Huaman J, Naidoo M, Zang X, Ogunwobi OO., Free PMC Article

    12/21/2019
    LRP1 is required for FN turnover in response to Hsp90 inhibition by novobiocin.

    LRP1 is required for novobiocin-mediated fibronectin turnover.
    Boel NM, Hunter MC, Edkins AL., Free PMC Article

    10/19/2019
    Endothelial alpha5beta1 integrins drive oxLDL-induced FN deposition and early atherogenic inflammation.

    Endothelial FN (Fibronectin) Deposition by α5β1 Integrins Drives Atherogenic Inflammation.
    Al-Yafeai Z, Yurdagul A Jr, Peretik JM, Alfaidi M, Murphy PA, Orr AW., Free PMC Article

    08/10/2019
    plasma FN exerts a critical role in safeguarding vascular organization and health, and that the two FN isoforms function in an overlapping as well as distinct manner to maintain postnatal vascular matrix integrity.

    Roles of fibronectin isoforms in neonatal vascular development and matrix integrity.
    Kumra H, Sabatier L, Hassan A, Sakai T, Mosher DF, Brinckmann J, Reinhardt DP., Free PMC Article

    05/11/2019
    Lack of Fibronectin Extra Domain A Alternative Splicing Exacerbates Endothelial Dysfunction in Diabetes.

    Lack of Fibronectin Extra Domain A Alternative Splicing Exacerbates Endothelial Dysfunction in Diabetes.
    Gortan Cappellari G, Barazzoni R, Cattin L, Muro AF, Zanetti M., Free PMC Article

    06/30/2018
    fibronectins from different sources contribute differentially to specific aspects of angiogenesis.

    Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion.
    Turner CJ, Badu-Nkansah K, Hynes RO., Free PMC Article

    06/23/2018
    Cdc42 bypasses the need for exogenous fibronectin by stimulating cellular fibronectin deposition under the newly formed lamellipodia.

    Cells lay their own tracks - optogenetic Cdc42 activation stimulates fibronectin deposition supporting directed migration.
    Zimmerman SP, Asokan SB, Kuhlman B, Bear JE., Free PMC Article

    06/9/2018
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