C-X-C Motif Chemokine Ligand 1 Promotes Colitis by Modulating the Gut Microbiota. | C-X-C Motif Chemokine Ligand 1 Promotes Colitis by Modulating the Gut Microbiota. Zhao H, Li W, Zhou X, Pan L, Feng Y, Gao P, Ji J, Zhang H, Zhao K, Wang C, Lu Z., Free PMC Article | 02/13/2024 |
Chemokine (C-X-C motif) ligand 1 maintains the immune surveillance function of natural killer cells via the PDK2/mTOR signaling pathway. | Chemokine (C-X-C motif) ligand 1 maintains the immune surveillance function of natural killer cells via the PDK2/mTOR signaling pathway. Zeng X, Dong X, Ma Y, Yao J. | 10/4/2023 |
Knockdown of CXCL1 improves ACLF by reducing neutrophil recruitment to attenuate ROS production and hepatocyte apoptosis. | Knockdown of CXCL1 improves ACLF by reducing neutrophil recruitment to attenuate ROS production and hepatocyte apoptosis. Tang S, Zhang J, Zhang L, Zhao Y, Xiao L, Zhang F, Li Q, Yang Y, Liu Q, Xu J, Li L., Free PMC Article | 09/20/2023 |
Dysregulation of CXCL1 Expression and Neutrophil Recruitment in Insulin Resistance and Diabetes-Related Periodontitis in Male Mice. | Dysregulation of CXCL1 Expression and Neutrophil Recruitment in Insulin Resistance and Diabetes-Related Periodontitis in Male Mice. Shinjo T, Onizuka S, Zaitsu Y, Ishikado A, Park K, Li Q, Yokomizo H, Zeze T, Sato K, St-Louis R, Fu J, I-Hsien W, Mizutani K, Hasturk H, Van Dyke TE, Nishimura F, King GL., | 06/23/2023 |
Transcriptomic Profiling Reveals Chemokine CXCL1 as a Mediator for Neutrophil Recruitment Associated With Blood-Retinal Barrier Alteration in Diabetic Retinopathy. | Transcriptomic Profiling Reveals Chemokine CXCL1 as a Mediator for Neutrophil Recruitment Associated With Blood-Retinal Barrier Alteration in Diabetic Retinopathy. Monickaraj F, Acosta G, Cabrera AP, Das A., | 06/12/2023 |
Murine Placental Erythroid Cells Are Mainly Represented by CD45[+] Immunosuppressive Erythroid Cells and Secrete CXCL1, CCL2, CCL3 and CCL4 Chemokines. | Murine Placental Erythroid Cells Are Mainly Represented by CD45(+) Immunosuppressive Erythroid Cells and Secrete CXCL1, CCL2, CCL3 and CCL4 Chemokines. Nazarov K, Perik-Zavodskii R, Perik-Zavodskaia O, Alrhmoun S, Volynets M, Shevchenko J, Sennikov S., Free PMC Article | 06/7/2023 |
Microglial IL-1RA ameliorates brain injury after ischemic stroke by inhibiting astrocytic CXCL1-mediated neutrophil recruitment and microvessel occlusion. | Microglial IL-1RA ameliorates brain injury after ischemic stroke by inhibiting astrocytic CXCL1-mediated neutrophil recruitment and microvessel occlusion. Huang X, Guo M, Zhang Y, Xie J, Huang R, Zuo Z, Saw PE, Cao M. | 05/12/2023 |
CXCL1/CXCR2 is involved in white matter injury in neonatal rats via the gut-brain axis. | CXCL1/CXCR2 is involved in white matter injury in neonatal rats via the gut-brain axis. Yang C, Feng Z, Deng H, Dai L, He L, Yin L, Zhao J., Free PMC Article | 12/3/2022 |
CXCL1-CXCR2 signalling mediates hypertensive retinopathy by inducing macrophage infiltration. | CXCL1-CXCR2 signalling mediates hypertensive retinopathy by inducing macrophage infiltration. Wang S, Bai J, Zhang YL, Lin QY, Han X, Qu WK, Zhang PF, Ge YS, Zhao Q, Li HH., Free PMC Article | 10/22/2022 |
C-X-C motif chemokine ligand 1 induced by Hedgehog signaling promotes mouse extrahepatic bile duct repair after acute injury. | C-X-C motif chemokine ligand 1 induced by Hedgehog signaling promotes mouse extrahepatic bile duct repair after acute injury. Mohamad Zaki NH, Shiota J, Calder AN, Keeley TM, Allen BL, Nakao K, Samuelson LC, Razumilava N., Free PMC Article | 10/15/2022 |
Fpr2/CXCL1/2 Controls Rapid Neutrophil Infiltration to Inhibit Streptococcus agalactiae Infection. | Fpr2/CXCL1/2 Controls Rapid Neutrophil Infiltration to Inhibit Streptococcus agalactiae Infection. Sun Z, Huang W, Zheng Y, Liu P, Yang W, Guo Z, Kong D, Lv Q, Zhou X, Du Z, Jiang H, Jiang Y., Free PMC Article | 02/19/2022 |
C-X-C motif chemokine ligand 1 and its receptor C-X-C motif chemokine receptor 2 in trigeminal ganglion contribute to nerve injury-induced orofacial mechanical allodynia. | C-X-C motif chemokine ligand 1 and its receptor C-X-C motif chemokine receptor 2 in trigeminal ganglion contribute to nerve injury-induced orofacial mechanical allodynia. Yang J, Liu F, Zhang YY, Lin J, Li YL, Zhou C, Li CJ, Shen JF. | 01/22/2022 |
MicroRNA-206 antagomiRenriched extracellular vesicles attenuate lung ischemiareperfusion injury through CXCL1 regulation in alveolar epithelial cells. | MicroRNA-206 antagomiR‒enriched extracellular vesicles attenuate lung ischemia‒reperfusion injury through CXCL1 regulation in alveolar epithelial cells. Cai J, Gehrau R, Tu Z, Leroy V, Su G, Shang J, Mas VR, Emtiazjoo A, Pelaez A, Atkinson C, Machuca T, Upchurch GR Jr, Sharma AK., Free PMC Article | 10/2/2021 |
GSDMD contributes to host defence against Staphylococcus aureus skin infection by suppressing the Cxcl1-Cxcr2 axis. | GSDMD contributes to host defence against Staphylococcus aureus skin infection by suppressing the Cxcl1-Cxcr2 axis. Liu ZZ, Yang YJ, Zhou FH, Ma K, Lin XQ, Yan SQ, Gao Y, Chen W., Free PMC Article | 09/11/2021 |
Homeobox B5 promotes metastasis and poor prognosis in Hepatocellular Carcinoma, via FGFR4 and CXCL1 upregulation. | Homeobox B5 promotes metastasis and poor prognosis in Hepatocellular Carcinoma, via FGFR4 and CXCL1 upregulation. He Q, Huang W, Liu D, Zhang T, Wang Y, Ji X, Xie M, Sun M, Tian D, Liu M, Xia L., Free PMC Article | 07/31/2021 |
Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions. | Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions. Sawant KV, Sepuru KM, Lowry E, Penaranda B, Frevert CW, Garofalo RP, Rajarathnam K., Free PMC Article | 05/8/2021 |
Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis. | Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis. Michael BD, Bricio-Moreno L, Sorensen EW, Miyabe Y, Lian J, Solomon T, Kurt-Jones EA, Luster AD., Free PMC Article | 05/8/2021 |
Schwann cell-derived CXCL1 contributes to human immunodeficiency virus type 1 gp120-induced neuropathic pain by modulating macrophage infiltration in mice. | Schwann cell-derived CXCL1 contributes to human immunodeficiency virus type 1 gp120-induced neuropathic pain by modulating macrophage infiltration in mice. Ntogwa M, Imai S, Hiraiwa R, Koyanagi M, Matsumoto M, Ogihara T, Nakagawa S, Omura T, Yonezawa A, Nakagawa T, Matsubara K. | 05/8/2021 |
Diesel Exhaust Particulates Induce Neutrophilic Lung Inflammation by Modulating Endoplasmic Reticulum Stress-Mediated CXCL1/KC Expression in Alveolar Macrophages. | Diesel Exhaust Particulates Induce Neutrophilic Lung Inflammation by Modulating Endoplasmic Reticulum Stress-Mediated CXCL1/KC Expression in Alveolar Macrophages. Kim DI, Song MK, Kim HI, Han KM, Lee K., Free PMC Article | 04/13/2021 |
Thiamine, riboflavin, and nicotinamide inhibit paclitaxel-induced allodynia by reducing TNF-alpha and CXCL-1 in dorsal root ganglia and thalamus and activating ATP-sensitive potassium channels. | Thiamine, riboflavin, and nicotinamide inhibit paclitaxel-induced allodynia by reducing TNF-α and CXCL-1 in dorsal root ganglia and thalamus and activating ATP-sensitive potassium channels. Braga AV, Costa SOAM, Rodrigues FF, Melo ISF, Morais MI, Coelho MM, Machado RR. | 11/21/2020 |
Mannan-binding lectin promotes keratinocyte to produce CXCL1 and enhances neutrophil infiltration at the early stages of psoriasis. | Mannan-binding lectin promotes keratinocyte to produce CXCL1 and enhances neutrophil infiltration at the early stages of psoriasis. Zeng J, Chen X, Lei K, Wang D, Lin L, Wang Y, Li Y, Liu Y, Zhang L, Zuo D, Sun L. | 10/24/2020 |
These effects were also reversed after silencing Cxcl1 in endothelial cells and its receptor chemokine (C-X-C motif) receptor 2 (Cxcr2) in astrocytes. | Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis. Liu XX, Yang L, Shao LX, He Y, Wu G, Bao YH, Lu NN, Gong DM, Lu YP, Cui TT, Sun NH, Chen DY, Shi WX, Fukunaga K, Chen HS, Chen Z, Han F, Lu YM., Free PMC Article | 07/18/2020 |
Results suggest that CXCL1 Chemokine (CXCL1) promotes neural stem cell proliferation through a mechanism involving the production of reactive oxygen species and the PI3K/Akt pathway. | CXCL1 promotes the proliferation of neural stem cells by stimulating the generation of reactive oxygen species in APP/PS1 mice. Shang Y, Tian L, Chen T, Liu X, Zhang J, Liu D, Wei J, Fang W, Chen Y, Shang D. | 07/4/2020 |
Our data suggest that L. major metalloproteases are involved in the direct cleavage and degradation of CXCL1, and a synthetic peptide spanning the CXCL1 cleavage site can be used to inhibit L. major metalloprotease activity | Leishmania major degrades murine CXCL1 - An immune evasion strategy. Yorek MS, Poudel B, Mazgaeen L, Pope RM, Wilson ME, Gurung P., Free PMC Article | 01/11/2020 |
Kupffer cells in the liver sense damage-associated molecular pattern molecules and release TNF-alpha to activate the NF-kappaB pathway in hepatocytes. | Kupffer cell-derived TNF-α promotes hepatocytes to produce CXCL1 and mobilize neutrophils in response to necrotic cells. Su L, Li N, Tang H, Lou Z, Chong X, Zhang C, Su J, Dong X., Free PMC Article | 11/30/2019 |