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    CTNND1 catenin delta 1 [ Homo sapiens (human) ]

    Gene ID: 1500, updated on 7-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Tag, you're it: G-ICAT identifies p120-cysteine glutathionylation triggering E-cadherin destabilization.

    Tag, you're it: G-ICAT identifies p120-cysteine glutathionylation triggering E-cadherin destabilization.
    Fridianto KT, Aye Y.

    01/3/2024
    The E3 ubiquitin ligase MIB1 suppresses breast cancer cell migration through regulating CTNND1 protein level.

    The E3 ubiquitin ligase MIB1 suppresses breast cancer cell migration through regulating CTNND1 protein level.
    Kanoh T, Lu J, Mizoguchi T, Itoh M.

    06/15/2023
    p120 regulates E-cadherin expression in nasal epithelial cells in chronic rhinosinusitis.

    p120 regulates E-cadherin expression in nasal epithelial cells in chronic rhinosinusitis.
    Li XL, Feng QM, Yang HN, Ruan JW, Kang YF, Yu ZE, Liu JX, Chen AN, Cui YH, Liu Z, Lu X.

    08/13/2022
    CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.

    CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.
    Yang M, Li S, Huang L, Zhao R, Dai E, Jiang X, He Y, Lu J, Peng L, Liu W, Zhang Z, Jiang D, Zhang Y, Jiang Z, Yang Y, Zhao P, Zhu X, Ding X, Yang Z., Free PMC Article

    07/30/2022
    Downregulated circular RNA hsa_circ_0005797 inhibits endometrial cancer by modulating microRNA-298/Catenin delta 1 signaling.

    Downregulated circular RNA hsa_circ_0005797 inhibits endometrial cancer by modulating microRNA-298/Catenin delta 1 signaling.
    Liu Y, Yuan H, He T., Free PMC Article

    07/16/2022
    Nuclear p120 catenin is a component of the perichromosomal layer and coordinates sister chromatid segregation during mitosis in lung cancer cells.

    Nuclear p120 catenin is a component of the perichromosomal layer and coordinates sister chromatid segregation during mitosis in lung cancer cells.
    Chow SE, Meir YJ, Li JM, Hsu PC, Yang CT., Free PMC Article

    06/11/2022
    Cytoplasmic P120ctn Promotes Gefitinib Resistance in Lung Cancer Cells by Activating PAK1 and ERK Pathway.

    Cytoplasmic P120ctn Promotes Gefitinib Resistance in Lung Cancer Cells by Activating PAK1 and ERK Pathway.
    Liu WW, Hu J, Wang R, Han Q, Liu Y, Wang S.

    03/12/2022
    p-120 Catenin is a Useful Diagnostic Biomarker for Distinguishing Plasmacytoid and Sarcomatoid Variants From Conventional Urothelial Carcinoma.

    p-120 Catenin is a Useful Diagnostic Biomarker for Distinguishing Plasmacytoid and Sarcomatoid Variants From Conventional Urothelial Carcinoma.
    Acosta AM, Barletta J, Sonpavde G, Schnitt S, Hirsch MS.

    11/13/2021
    PLEKHA7, an Apical Adherens Junction Protein, Suppresses Inflammatory Breast Cancer in the Context of High E-Cadherin and p120-Catenin Expression.

    PLEKHA7, an Apical Adherens Junction Protein, Suppresses Inflammatory Breast Cancer in the Context of High E-Cadherin and p120-Catenin Expression.
    Pence LJ, Kourtidis A, Feathers RW, Haddad MT, Sotiriou S, Decker PA, Nassar A, Ocal IT, Shah SS, Anastasiadis PZ., Free PMC Article

    09/11/2021
    Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated beta-catenin pathway and EMT in colorectal cancer.

    Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
    Liu D, Zhang H, Cui M, Chen C, Feng Y., Free PMC Article

    09/4/2021
    APC regulation of ESRP1 and p120-catenin isoforms in colorectal cancer cells.

    APC regulation of ESRP1 and p120-catenin isoforms in colorectal cancer cells.
    Faux MC, King LE, Kane SR, Love C, Sieber OM, Burgess AW., Free PMC Article

    08/14/2021
    Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome.

    Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome.
    Alharatani R, Ververi A, Beleza-Meireles A, Ji W, Mis E, Patterson QT, Griffin JN, Bhujel N, Chang CA, Dixit A, Konstantino M, Healy C, Hannan S, Neo N, Cash A, Li D, Bhoj E, Zackai EH, Cleaver R, Baralle D, McEntagart M, Newbury-Ecob R, Scott R, Hurst JA, Au PYB, Hosey MT, Khokha M, Marciano DK, Lakhani SA, Liu KJ., Free PMC Article

    08/14/2021
    delta-Catenin Participates in EGF/AKT/p21(Waf) Signaling and Induces Prostate Cancer Cell Proliferation and Invasion.

    δ-Catenin Participates in EGF/AKT/p21(Waf) Signaling and Induces Prostate Cancer Cell Proliferation and Invasion.
    Shen Y, Lee HJ, Zhou R, Kim H, Chen G, Cho YC, Kim K., Free PMC Article

    06/19/2021
    delta-Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting beta-catenin nuclear localization and activating its downstream target genes.

    δ-Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β-catenin nuclear localization and activating its downstream target genes.
    Ju L, Shan L, Yin B, Song Y., Free PMC Article

    04/24/2021
    Twist2 is NFkB-responsive when p120-catenin is inactivated and EGFR is overexpressed in esophageal keratinocytes.

    Twist2 is NFkB-responsive when p120-catenin is inactivated and EGFR is overexpressed in esophageal keratinocytes.
    Lehman HL, Kidacki M, Stairs DB., Free PMC Article

    03/28/2021
    The circular RNA circMAST1 promotes hepatocellular carcinoma cell proliferation and migration by sponging miR-1299 and regulating CTNND1 expression.

    The circular RNA circMAST1 promotes hepatocellular carcinoma cell proliferation and migration by sponging miR-1299 and regulating CTNND1 expression.
    Yu X, Sheng P, Sun J, Zhao X, Zhang J, Li Y, Zhang Y, Zhang W, Wang J, Liu K, Zhu D, Jiang H., Free PMC Article

    03/13/2021
    Invasive plasmacytoid urothelial carcinoma: A comparative study of E-cadherin and P120 catenin.

    Invasive plasmacytoid urothelial carcinoma: A comparative study of E-cadherin and P120 catenin.
    Sangoi AR, Chan E, Stohr BA, Kunju LP.

    02/20/2021
    Loss of p120ctn causes EGFR-targeted therapy resistance and failure.

    Loss of p120ctn causes EGFR-targeted therapy resistance and failure.
    Landmesser ME, Raup-Konsavage WM, Lehman HL, Stairs DB., Free PMC Article

    12/19/2020
    Intratumor delta-catenin heterogeneity driven by genomic rearrangement dictates growth factor dependent prostate cancer progression.

    Intratumor δ-catenin heterogeneity driven by genomic rearrangement dictates growth factor dependent prostate cancer progression.
    Li M, Nopparat J, Aguilar BJ, Chen YH, Zhang J, Du J, Ai X, Luo Y, Jiang Y, Boykin C, Lu Q., Free PMC Article

    12/5/2020
    MicroRNA-96-5p represses breast cancer proliferation and invasion through Wnt/beta-catenin signaling via targeting CTNND1.

    MicroRNA-96-5p represses breast cancer proliferation and invasion through Wnt/β-catenin signaling via targeting CTNND1.
    Gao XH, Zhang YL, Zhang ZY, Guo SS, Chen XB, Guo YZ., Free PMC Article

    11/21/2020
    E-cadherin and p120ctn protein expression are lost in hidradenitis suppurativa lesions.

    E-cadherin and p120ctn protein expression are lost in hidradenitis suppurativa lesions.
    Nelson AM, Cong Z, Gettle SL, Longenecker AL, Kidacki M, Kirby JS, Adams DR, Stairs DB, Danby FW.

    10/31/2020
    An LTR Retrotransposon-Derived Long Noncoding RNA lncMER52A Promotes Hepatocellular Carcinoma Progression by Binding p120-Catenin.

    An LTR Retrotransposon-Derived Long Noncoding RNA lncMER52A Promotes Hepatocellular Carcinoma Progression by Binding p120-Catenin.
    Wu Y, Zhao Y, Huan L, Zhao J, Zhou Y, Xu L, Hu Z, Liu Y, Chen Z, Wang L, Huang S, He X, Liang L.

    10/3/2020
    hsa_circ_0002577 might act as a sponge for miR-197, and CTNND1 was revealed to be a target gene of miR-197.

    Hsa_circ_0002577 promotes endometrial carcinoma progression via regulating miR-197/CTNND1 axis and activating Wnt/β-catenin pathway.
    Shen Q, He T, Yuan H., Free PMC Article

    06/13/2020
    The increase in invasive capacity induced by bevacizumab therapy was associated with upregulation of delta-catenin expression in invasive tumor cells. This finding suggests that delta-catenin is related to tumor invasion and migration.

    δ-Catenin Promotes Bevacizumab-Induced Glioma Invasion.
    Shimizu T, Ishida J, Kurozumi K, Ichikawa T, Otani Y, Oka T, Tomita Y, Hattori Y, Uneda A, Matsumoto Y, Date I.

    02/29/2020
    p120ctn in exosomes secreted from liver cancer cells suppresses Hepatocellular carcinoma cell proliferation and metastasis and expansion of liver cancer stem cells

    Exosome-transmitted p120-catenin suppresses hepatocellular carcinoma progression via STAT3 pathways.
    Cheng Z, Lei Z, Yang P, Si A, Xiang D, Tang X, Guo G, Zhou J, Hüser N.

    11/9/2019
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