| Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway. | Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway.
Hu L, Zheng C, Kong Y, Luo Z, Huang F, Zhu Z, Li Q, Liang M., Free PMC Article | 02/20/2024 |
| CTSG Suppresses Colorectal Cancer Progression through Negative Regulation of Akt/mTOR/Bcl2 Signaling Pathway. | CTSG Suppresses Colorectal Cancer Progression through Negative Regulation of Akt/mTOR/Bcl2 Signaling Pathway.
Chan S, Wang X, Wang Z, Du Y, Zuo X, Chen J, Sun R, Zhang Q, Lin L, Yang Y, Yu Z, Zhao H, Zhang H, Chen W., Free PMC Article | 05/15/2023 |
| Downregulation of interleukin 36gamma and its cleaver cathepsin G following treatment with narrow-band ultraviolet B phototherapy in psoriasis vulgaris. | Downregulation of interleukin 36γ and its cleaver cathepsin G following treatment with narrow-band ultraviolet B phototherapy in psoriasis vulgaris.
El-Kalioby M, El-Komy MHM, Said ER, Amer MA, Saadi DG, Nouredin Mohammed F, Rashed LA, El Desouky ED, AlOrbani AM. | 07/16/2022 |
| Cathepsin G-induced malignant progression of MCF-7 cells involves suppression of PAF signaling through induced expression of PAFAH1B2. | Cathepsin G-induced malignant progression of MCF-7 cells involves suppression of PAF signaling through induced expression of PAFAH1B2.
Tanigawa K, Kiriya M, Hayashi Y, Shinden Y, Kijima Y, Natsugoe S, Sumimoto T, Morimoto-Kamata R, Yui S, Hama K, Yokoyama K, Nakamura Y, Suzuki K, Nojiri H, Inoue K, Karasawa K. | 06/11/2022 |
| Gene body methylation facilitates the transcription of CTSG via antisense lncRNA AL136018.1 in dermatomyositic myoideum. | Gene body methylation facilitates the transcription of CTSG via antisense lncRNA AL136018.1 in dermatomyositic myoideum.
Liang Y, Peng Y. | 09/4/2021 |
| Cathepsin G-Induced Insulin-Like Growth Factor (IGF) Elevation in MCF-7 Medium Is Caused by Proteolysis of IGF Binding Protein (IGFBP)-2 but Not of IGF-1. | Cathepsin G-Induced Insulin-Like Growth Factor (IGF) Elevation in MCF-7 Medium Is Caused by Proteolysis of IGF Binding Protein (IGFBP)-2 but Not of IGF-1.
Morimoto-Kamata R, Tsuji D, Yui S. | 07/17/2021 |
| Role of DNA methylation on human CTSG in dermatomyositic myoideum. | Role of DNA methylation on human CTSG in dermatomyositic myoideum.
Peng Y, Sun X, Liang Y. | 07/10/2021 |
| Cathepsin G-Not Only Inflammation: The Immune Protease Can Regulate Normal Physiological Processes. | Cathepsin G-Not Only Inflammation: The Immune Protease Can Regulate Normal Physiological Processes.
Zamolodchikova TS, Tolpygo SM, Svirshchevskaya EV., Free PMC Article | 03/20/2021 |
| Local structural plasticity of the Staphylococcus aureus evasion protein EapH1 enables engagement with multiple neutrophil serine proteases. | Local structural plasticity of the Staphylococcus aureus evasion protein EapH1 enables engagement with multiple neutrophil serine proteases.
Herdendorf TJ, Stapels DAC, Rooijakkers SHM, Geisbrecht BV., Free PMC Article | 12/26/2020 |
| Results show that cathepsin G (CTSG) N125S (AG) genotype was significantly more frequent among osteomyelitis patients than controls. | The N125S polymorphism in the cathepsin G gene (rs45567233) is associated with susceptibility to osteomyelitis in a Spanish population.
Pérez-Is L, Ocaña MG, Montes AH, Carton JA, Álvarez V, Meana Á, Fierer J, Valle-Garay E, Asensi V., Free PMC Article | 03/21/2020 |
| High CTSG expression is associated with antidiastole of tuberculous pleural effusion. | Potential biomarkers for antidiastole of tuberculous and malignant pleural effusion by proteome analysis.
Shi J, Li P, Zhou L, Qi S, Wang B, Li D, Duan L, Chen WX, Xia J, Zou L, Yang S. | 01/11/2020 |
| Cathepsin G in human atherosclerotic lesions is largely derived from monocytes. Activated monocytes may contribute to atherogenesis by generating modified LDL particles with increased proteoglycan binding, to enhance LDL retention. | Human mast cell neutral proteases generate modified LDL particles with increased proteoglycan binding.
Maaninka K, Nguyen SD, Mäyränpää MI, Plihtari R, Rajamäki K, Lindsberg PJ, Kovanen PT, Öörni K. | 10/26/2019 |
| The results demonstrate that cathepsin G is directly engaged in caspase-4 activation by a bacterial ligand, which is responsible for cell death and IL-1alpha secretion in HGFs. | Caspase-4 activation by a bacterial surface protein is mediated by cathepsin G in human gingival fibroblasts.
Jun HK, Jung YJ, Ji S, An SJ, Choi BK., Free PMC Article | 08/24/2019 |
| Neutrophil extracellular traps promote endothelial cell activation and increased thrombogenicity through concerted action of IL-1alpha and cathepsin G and tissue factor production. | Neutrophil Extracellular Traps Induce Endothelial Cell Activation and Tissue Factor Production Through Interleukin-1α and Cathepsin G.
Folco EJ, Mawson TL, Vromman A, Bernardes-Souza B, Franck G, Persson O, Nakamura M, Newton G, Luscinskas FW, Libby P., Free PMC Article | 07/27/2019 |
| The lung extracellular matrix is vulnerable to pathological structural changes upon upregulation of serine proteases, including cathepsin G (CG) and proteinase 3 (PR3). | Lung tissue destruction by proteinase 3 and cathepsin G mediated elastin degradation is elevated in chronic obstructive pulmonary disease.
Gudmann NS, Manon-Jensen T, Sand JMB, Diefenbach C, Sun S, Danielsen A, Karsdal MA, Leeming DJ. | 02/23/2019 |
| CTSG was increased in peripheral blood mononuclear cells and muscle tissues of dermatomyositis (DM) patients, and CTSG activity was higher in the serum of DM patients | The role and mechanism of cathepsin G in dermatomyositis.
Gao S, Zhu H, Yang H, Zhang H, Li Q, Luo H. | 05/19/2018 |
| CatG can be used as a novel marker to distinguish different NK cell subsets and MARS116 is applicable to determine cell surface CatG activity by flow cytometry. | Cell surface cathepsin G activity differs between human natural killer cell subsets.
Penczek A, Sienczyk M, Wirtz CR, Burster T. | 12/9/2017 |
| Results provide evidence that cathepsin G (GC) activates IGF-1R by stimulating IGF-1 release from MCF-7 cells, and that IGF-1R activation is required for CG-induced cell aggregation. | Insulin-like growth factor-1 signaling is responsible for cathepsin G-induced aggregation of breast cancer MCF-7 cells.
Morimoto-Kamata R, Yui S., Free PMC Article | 09/30/2017 |
| Cleavage of the alarmins by Human mast cell chymase and human neutrophil cathepsin G suggests a function in regulating excessive inflammation. | Highly Selective Cleavage of Cytokines and Chemokines by the Human Mast Cell Chymase and Neutrophil Cathepsin G.
Fu Z, Thorpe M, Alemayehu R, Roy A, Kervinen J, de Garavilla L, Åbrink M, Hellman L. | 09/2/2017 |
| Data show that lactoferrin (LF) increases the catalytic activity of cathepsin G (CatG) at physiological concentration. | Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G.
Eipper S, Steiner R, Lesner A, Sienczyk M, Palesch D, Halatsch ME, Zaczynska E, Heim C, Hartmann MD, Zimecki M, Wirtz CR, Burster T., Free PMC Article | 08/6/2016 |
| CatG is an essential protease for regulating MHC I molecules | Cathepsin G-mediated proteolytic degradation of MHC class I molecules to facilitate immune detection of human glioblastoma cells.
Palesch D, Wagner J, Meid A, Molenda N, Sienczyk M, Burkhardt J, Münch J, Prokop L, Stevanovic S, Westhoff MA, Halatsch ME, Wirtz CR, Zimecki M, Burster T. | 07/30/2016 |
| Patients with certain polymorphisms in the CTSG gene had lower risk for chronic postsurgical pain compared with wild-types. | Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study.
Liu X, Tian Y, Meng Z, Chen Y, Ho IH, Choy KW, Lichtner P, Wong SH, Yu J, Gin T, Wu WK, Cheng CH, Chan MT. | 12/19/2015 |
| These in vivo data provide, for the first time, compelling evidence of the collateral involvement of cathepsin G, NE, and proteinase 3 in cigarette smoke-induced tissue damage and emphysema | Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and emphysema.
Guyot N, Wartelle J, Malleret L, Todorov AA, Devouassoux G, Pacheco Y, Jenne DE, Belaaouaj A. | 04/4/2015 |
| expression levels of ELANE and CTSG were determined by quantitative real-time PCR | Quantitative analysis of elastase and cathepsin G mRNA levels in peripheral blood CD14(+) cells from patients with rheumatoid arthritis.
Trzybulska D, Olewicz-Gawlik A, Graniczna K, Kisiel K, Moskal M, Cieślak D, Sikora J, Hrycaj P. | 02/21/2015 |
| Elastase and cathepsin G are elevated in the plasma of HD patients, originating from primed PMNLs. In these patients, chronic elevation of these enzymes contributes to cleavage of VE-cadherin and possible disruption of endothelial integrity. | Elastase and cathepsin G from primed leukocytes cleave vascular endothelial cadherin in hemodialysis patients.
Cohen-Mazor M, Mazor R, Kristal B, Sela S., Free PMC Article | 02/14/2015 |