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    Foxq1 forkhead box Q1 [ Mus musculus (house mouse) ]

    Gene ID: 15220, updated on 12-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    FOXQ1 inhibits the progression of osteoarthritis by regulating pyroptosis.

    FOXQ1 inhibits the progression of osteoarthritis by regulating pyroptosis.
    Luo Z, Zeng H, Yang K, Wang Y., Free PMC Article

    04/11/2024
    FOXQ1 inhibits breast cancer ferroptosis and progression via the circ_0000643/miR-153/SLC7A11 axis.

    FOXQ1 inhibits breast cancer ferroptosis and progression via the circ_0000643/miR-153/SLC7A11 axis.
    Huang X, Wu J, Wang Y, Xian Z, Li J, Qiu N, Li H.

    09/11/2023
    STUB1 directs FOXQ1-mediated transactivation of Ldha gene and facilitates lactate production in mouse Sertoli cells.

    STUB1 directs FOXQ1-mediated transactivation of Ldha gene and facilitates lactate production in mouse Sertoli cells.
    Yang Y, Ma Y, Li M, Zhu H, Shi P, An R.

    08/25/2023
    Identification of testicular Foxq1 as a critical modulator of lactate metabolism in mouse Sertoli cells.

    Identification of testicular Foxq1 as a critical modulator of lactate metabolism in mouse Sertoli cells.
    Liu Z, Yuan M, Meng X, Bie H, Yao S.

    10/23/2021
    FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/beta-catenin signaling by binding with ANXA2.

    FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2.
    Xiang L, Zheng J, Zhang M, Ai T, Cai B., Free PMC Article

    07/3/2021
    data reveal that FOXQ1 acts as a critical mediator of BRAF(V600E)-dependent regulation of MITF levels, thus providing a novel link between two major signal transduction pathways controlling MITF and differentiation in melanocytic cells.

    FOXQ1 controls the induced differentiation of melanocytic cells.
    Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Kolesnikova M, Roll MV, Jowdy P, Wolff DW, Polechetti A, Yun DH, Lipchick BC, Paul LM, Wrazen B, Moparthy K, Mudambi S, Morozevich GE, Georgieva SG, Wang J, Shafirstein G, Liu S, Kandel ES, Berman AE, Box NF, Paragh G, Nikiforov MA., Free PMC Article

    09/21/2019
    the Fox transcription factor binding motif was frequently observed within EWS-FLI1 peaks and Foxq1 was identified as the cooperative partner that interacts with the EWS portion of EWS-FLI1.

    EWS-FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma.
    Shimizu R, Tanaka M, Tsutsumi S, Aburatani H, Yamazaki Y, Homme M, Kitagawa Y, Nakamura T., Free PMC Article

    10/20/2018
    FOXQ1 is a novel factor involved in regulating hepatic gluconeogenesis, and the decreased FOXQ1 expression in liver may contribute to the development of type 2 diabetes.

    The hepatic FOXQ1 transcription factor regulates glucose metabolism in mice.
    Cui Y, Qiao A, Jiao T, Zhang H, Xue Y, Zou Y, Cui A, Fang F, Chang Y.

    09/2/2017
    R164C mutation in FOXQ1 H3 domain affects formation of the hair medulla in mice.

    R164C mutation in FOXQ1 H3 domain affects formation of the hair medulla.
    Wu B, Herbert Pratt C, Potter CS, Silva KA, Kennedy V, Sundberg JP., Free PMC Article

    09/28/2013
    This study has elucidated the functional impact of FoxQ1 on epithelial differentiation.

    The Forkhead factor FoxQ1 influences epithelial differentiation.
    Feuerborn A, Srivastava PK, Küffer S, Grandy WA, Sijmonsma TP, Gretz N, Brors B, Gröne HJ.

    01/29/2011
    Transcription factor foxq1 controls MUC5AC gene expression and granule content in mouse stomach surface mucous cells.

    Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells.
    Verzi MP, Khan AH, Ito S, Shivdasani RA., Free PMC Article

    01/21/2010
    Ultrastructural analysis suggests that the gastric acid secretion defect in Foxq1-deficient mice might be due to impairment in the fusion of cytoplasmic tubulovesicles to the apical membrane of secretory canaliculi.

    Impairment of gastric acid secretion and increase of embryonic lethality in Foxq1-deficient mice.
    Goering W, Adham IM, Pasche B, Manner J, Ochs M, Engel W, Zoll B.

    01/21/2010
    satin hair mutant gene Foxq1 is among multiple and functionally diverse regulatory targets for Hoxc13 during hair follicle differentiation

    Evidence that the satin hair mutant gene Foxq1 is among multiple and functionally diverse regulatory targets for Hoxc13 during hair follicle differentiation.
    Potter CS, Peterson RL, Barth JL, Pruett ND, Jacobs DF, Kern MJ, Argraves WS, Sundberg JP, Awgulewitsch A.

    01/21/2010
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