| CK1alpha deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3beta pathway and inhibiting Foxa2 expression through p53 pathwaydagger. | CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway†.
Zhang D, Lu C, Zhou Y, Luo X, Guo H, Zhang J, Gao Q, Liu H, Shang C, Cui S. | 02/20/2024 |
| Pioneer Factor Foxa2 Mediates Chromatin Conformation Changes for Activation of Bile Acid Targets of FXR. | Pioneer Factor Foxa2 Mediates Chromatin Conformation Changes for Activation of Bile Acid Targets of FXR.
Hao Y, Han L, Wu A, Bochkis IM., Free PMC Article | 01/26/2024 |
| FXR controls insulin content by regulating Foxa2-mediated insulin transcription. | FXR controls insulin content by regulating Foxa2-mediated insulin transcription.
Yan D, Lv M, Kong X, Feng L, Ying Y, Liu W, Wang X, Ma X. | 01/17/2024 |
| Foxa2 attenuates steatosis and inhibits the NF-kappaB/IKK signaling pathway in nonalcoholic fatty liver disease. | Foxa2 attenuates steatosis and inhibits the NF-κB/IKK signaling pathway in nonalcoholic fatty liver disease.
Yang L, Ma Q, Chen J, Kong X, Yu X, Wang W., Free PMC Article | 12/20/2023 |
| Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2. | Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2.
Xu Y, Zhu Y, Wu Z, Li S, Shao M, Tao Q, Xu Q, Chen Y, Shu Y, Chen M, Zhou Y, Shi Y., Free PMC Article | 10/26/2023 |
| Upregulation of FOXA2 in uterine luminal epithelium and vaginal basal epithelium of epiERalpha-/- (Esr1fl/flWnt7aCre/+) micedagger. | Upregulation of FOXA2 in uterine luminal epithelium and vaginal basal epithelium of epiERα-/- (Esr1fl/flWnt7aCre/+) mice†.
Hancock JM, Li Y, Martin TE, Andersen CL, Ye X., Free PMC Article | 03/17/2023 |
| FOXA2 prevents hyperbilirubinaemia in acute liver failure by maintaining apical MRP2 expression. | FOXA2 prevents hyperbilirubinaemia in acute liver failure by maintaining apical MRP2 expression.
Wang S, Feng R, Wang SS, Liu H, Shao C, Li Y, Link F, Munker S, Liebe R, Meyer C, Burgermeister E, Ebert M, Dooley S, Ding H, Weng H. | 02/16/2023 |
| Redistribution of lamina-associated domains reshapes binding of pioneer factor FOXA2 in development of nonalcoholic fatty liver disease. | Redistribution of lamina-associated domains reshapes binding of pioneer factor FOXA2 in development of nonalcoholic fatty liver disease.
Wei X, Murphy MA, Reddy NA, Hao Y, Eggertsen TG, Saucerman JJ, Bochkis IM., Free PMC Article | 01/21/2023 |
| FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine prostate cancer. | FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine prostate cancer.
Han M, Li F, Zhang Y, Dai P, He J, Li Y, Zhu Y, Zheng J, Huang H, Bai F, Gao D. | 12/3/2022 |
| The Pioneer Transcription Factor Foxa2 Modulates T Helper Differentiation to Reduce Mouse Allergic Airway Disease. | The Pioneer Transcription Factor Foxa2 Modulates T Helper Differentiation to Reduce Mouse Allergic Airway Disease.
Yánez DC, Lau CI, Papaioannou E, Chawda MM, Rowell J, Ross S, Furmanski A, Crompton T., Free PMC Article | 09/3/2022 |
| FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma. | FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma.
Orstad G, Fort G, Parnell TJ, Jones A, Stubben C, Lohman B, Gillis KL, Orellana W, Tariq R, Klingbeil O, Kaestner K, Vakoc CR, Spike BT, Snyder EL., Free PMC Article | 08/20/2022 |
| Targeted depletion of uterine glandular Foxa2 induces embryonic diapause in mice. | Targeted depletion of uterine glandular Foxa2 induces embryonic diapause in mice.
Matsuo M, Yuan J, Kim YS, Dewar A, Fujita H, Dey SK, Sun X., Free PMC Article | 08/13/2022 |
| FOXA2 suppresses endometrial carcinogenesis and epithelial-mesenchymal transition by regulating enhancer activity. | FOXA2 suppresses endometrial carcinogenesis and epithelial-mesenchymal transition by regulating enhancer activity.
Sahoo SS, Ramanand SG, Gao Y, Abbas A, Kumar A, Cuevas IC, Li HD, Aguilar M, Xing C, Mani RS, Castrillon DH., Free PMC Article | 06/18/2022 |
| Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes. | Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes.
Bell N, Bhagat S, Muruganandan S, Kim R, Ho K, Pierce R, Kozhemyakina E, Lassar AB, Gamer L, Rosen V, Ionescu AM., Free PMC Article | 05/28/2022 |
| Pioneer factor Foxa2 enables ligand-dependent activation of type II nuclear receptors FXR and LXRalpha. | Pioneer factor Foxa2 enables ligand-dependent activation of type II nuclear receptors FXR and LXRα.
Kain J, Wei X, Reddy NA, Price AJ, Woods C, Bochkis IM., Free PMC Article | 03/26/2022 |
| Fetal Brain Elicits Sexually Conflicting Transcriptional Response to the Ablation of Uterine Forkhead Box A2 (Foxa2) in Mice. | Fetal Brain Elicits Sexually Conflicting Transcriptional Response to the Ablation of Uterine Forkhead Box A2 (Foxa2) in Mice.
Dhakal P, Strawn M, Samal A, Behura SK., Free PMC Article | 10/30/2021 |
| The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection. | The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection.
Lau CI, Rowell J, Yanez DC, Solanki A, Ross S, Ono M, Crompton T., Free PMC Article | 10/16/2021 |
| Embryonic liver developmental trajectory revealed by single-cell RNA sequencing in the Foxa2(eGFP) mouse. | Embryonic liver developmental trajectory revealed by single-cell RNA sequencing in the Foxa2(eGFP) mouse.
Mu T, Xu L, Zhong Y, Liu X, Zhao Z, Huang C, Lan X, Lufei C, Zhou Y, Su Y, Xu L, Jiang M, Zhou H, Lin X, Wu L, Peng S, Liu S, Brix S, Dean M, Dunn NR, Zaret KS, Fu XY, Hou Y., Free PMC Article | 06/26/2021 |
| Overexpression of FOXA2 attenuates cigarette smoke-induced cellular senescence and lung inflammation through inhibition of the p38 and Erk1/2 MAPK pathways. | Overexpression of FOXA2 attenuates cigarette smoke-induced cellular senescence and lung inflammation through inhibition of the p38 and Erk1/2 MAPK pathways.
Tao Y, Sun Y, Wu B, Xu D, Yang J, Gu L, Du C. | 06/26/2021 |
| Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh. | Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh.
Gredler ML, Patterson SE, Seifert AW, Cohn MJ., Free PMC Article | 02/6/2021 |
| PPARbeta/delta Agonism Upregulates Forkhead Box A2 to Reduce Inflammation in C2C12 Myoblasts and in Skeletal Muscle. | PPARβ/δ Agonism Upregulates Forkhead Box A2 to Reduce Inflammation in C2C12 Myoblasts and in Skeletal Muscle.
Phua WWT, Tan WR, Yip YS, Hew ID, Wee JWK, Cheng HS, Leow MKS, Wahli W, Tan NS., Free PMC Article | 01/9/2021 |
| Sexually dimorphic effects of forkhead box a2 (FOXA2) and uterine glands on decidualization and fetoplacental development. | Sexually dimorphic effects of forkhead box a2 (FOXA2) and uterine glands on decidualization and fetoplacental development.
Dhakal P, Kelleher AM, Behura SK, Spencer TE., Free PMC Article | 11/21/2020 |
| Loss of FoxA2 accelerates neoplastic changes in the intrahepatic bile duct partly via the MAPK signaling pathway. | Loss of FoxA2 accelerates neoplastic changes in the intrahepatic bile duct partly via the MAPK signaling pathway.
Shen J, Zhou Y, Zhang X, Peng W, Peng C, Zhou Q, Li C, Wen T, Shi Y., Free PMC Article | 09/5/2020 |
| Study indicated that Foxa2 plays an important role in Th2-dominated airway inflammation against invading bacteria. Conditional deletion of Foxa2 in respiratory epithelial cells can reduce pulmonary's defense against bacterial invasion by inhibiting DEFB1expression. | Molecular characterization of pulmonary defenses against bacterial invasion in allergic asthma: The role of Foxa2 in regulation of β-defensin 1.
Wei C, Tang X, Wang F, Li Y, Sun L, Luo F., Free PMC Article | 03/28/2020 |
| low levels of epithelial SCGB1A1 in asthma are caused by reduced FOXA2 expression. | The Club Cell Marker SCGB1A1 Downstream of FOXA2 is Reduced in Asthma.
Zhu L, An L, Ran D, Lizarraga R, Bondy C, Zhou X, Harper RW, Liao SY, Chen Y., Free PMC Article | 02/22/2020 |