| PRMT1 promotes pancreatic cancer development and resistance to chemotherapy. | PRMT1 promotes pancreatic cancer development and resistance to chemotherapy.
Ku B, Eisenbarth D, Baek S, Jeong TK, Kang JG, Hwang D, Noh MG, Choi C, Choi S, Seol T, Kim H, Kim YH, Woo SM, Kong SY, Lim DS., Free PMC Article | 03/22/2024 |
| Protein arginine methyltransferase 1 is required for the maintenance of adult small intestinal and colonic epithelial cell homeostasis. | Protein arginine methyltransferase 1 is required for the maintenance of adult small intestinal and colonic epithelial cell homeostasis.
Peng Z, Bao L, Shi B, Shi YB., Free PMC Article | 01/9/2024 |
| PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma. | PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma.
Feng G, Chen C, Luo Y., Free PMC Article | 11/13/2023 |
| The arginine methyltransferase Prmt1 coordinates the germline arginine methylome essential for spermatogonial homeostasis and male fertility. | The arginine methyltransferase Prmt1 coordinates the germline arginine methylome essential for spermatogonial homeostasis and male fertility.
Azhar M, Xu C, Jiang X, Li W, Cao Y, Zhu X, Xing X, Wu L, Zou J, Meng L, Cheng Y, Han W, Bao J., Free PMC Article | 11/2/2023 |
| Inhibition of PRMT1 alleviates sepsis-induced acute kidney injury in mice by blocking the TGF-beta1 and IL-6 trans-signaling pathways. | Inhibition of PRMT1 alleviates sepsis-induced acute kidney injury in mice by blocking the TGF-β1 and IL-6 trans-signaling pathways.
Zhu Y, Wang L, Liu R, Ding X, Yin S, Chen Y, Zhu C, Wang Z, Li W., Free PMC Article | 10/5/2023 |
| PRMT1-mediated arginine methylation promotes postnatal calvaria bone formation through BMP-Smad signaling. | PRMT1-mediated arginine methylation promotes postnatal calvaria bone formation through BMP-Smad signaling.
Ye H, Cao L, Jackson-Weaver O, Zheng L, Gou Y. | 09/20/2023 |
| PRMT1 reverts the immune escape of necroptotic colon cancer through RIP3 methylation. | PRMT1 reverts the immune escape of necroptotic colon cancer through RIP3 methylation.
Zhang L, He Y, Jiang Y, Wu Q, Liu Y, Xie Q, Zou Y, Wu J, Zhang C, Zhou Z, Bian XW, Jin G., Free PMC Article | 08/10/2023 |
| Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice. | Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice.
Litzler LC, Zahn A, Dionne KL, Sprumont A, Ferreira SR, Slattery MRF, Methot SP, Patenaude AM, Hébert S, Kabir N, Subramani PG, Jung S, Richard S, Kleinman CL, Di Noia JM., Free PMC Article | 06/22/2023 |
| PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity. | PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity.
Liu J, Bu X, Chu C, Dai X, Asara JM, Sicinski P, Freeman GJ, Wei W., Free PMC Article | 05/19/2023 |
| Protein arginine methyltransferase PRMT1 promotes adipogenesis by modulating transcription factors C/EBPbeta and PPARgamma. | Protein arginine methyltransferase PRMT1 promotes adipogenesis by modulating transcription factors C/EBPβ and PPARγ.
Zhu Q, Wang D, Liang F, Tong X, Liang Z, Wang X, Chen Y, Mo D., Free PMC Article | 10/15/2022 |
| Inhibition of protein arginine methyltransferase 1 alleviates liver fibrosis by attenuating the activation of hepatic stellate cells in mice. | Inhibition of protein arginine methyltransferase 1 alleviates liver fibrosis by attenuating the activation of hepatic stellate cells in mice.
Yan FZ, Qian H, Liu F, Ding CH, Liu SQ, Xiao MC, Chen SJ, Zhang X, Luo C, Xie WF. | 08/20/2022 |
| Klf4 methylated by Prmt1 restrains the commitment of primitive endoderm. | Klf4 methylated by Prmt1 restrains the commitment of primitive endoderm.
Zuo ZY, Yang GH, Wang HY, Liu SY, Zhang YJ, Cai Y, Chen F, Dai H, Xiao Y, Cheng MB, Huang Y, Zhang Y., Free PMC Article | 05/7/2022 |
| Inducible Prmt1 ablation in adult vascular smooth muscle leads to contractile dysfunction and aortic dissection. | Inducible Prmt1 ablation in adult vascular smooth muscle leads to contractile dysfunction and aortic dissection.
Pyun JH, Ahn BY, Vuong TA, Kim SW, Jo Y, Jeon J, Baek SH, Kim J, Park S, Bae GU, Choi JH, Kim JR, Ryu D, Lee SJ, Kang JS., Free PMC Article | 04/9/2022 |
| The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation. | The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation.
Yan Z, Wu H, Liu H, Zhao G, Zhang H, Zhuang W, Liu F, Zheng Y, Liu B, Zhang L, Gao C. | 02/19/2022 |
| Coordinated regulation of the ribosome and proteasome by PRMT1 in the maintenance of neural stemness in cancer cells and neural stem cells. | Coordinated regulation of the ribosome and proteasome by PRMT1 in the maintenance of neural stemness in cancer cells and neural stem cells.
Chen L, Zhang M, Fang L, Yang X, Cao N, Xu L, Shi L, Cao Y., Free PMC Article | 12/18/2021 |
| Depletion of Prmt1 in Adipocytes Impairs Glucose Homeostasis in Diet-Induced Obesity. | Depletion of Prmt1 in Adipocytes Impairs Glucose Homeostasis in Diet-Induced Obesity.
Choi S, Choi D, Lee YK, Ahn SH, Seong JK, Chi SW, Oh TJ, Choi SH, Koo SH. | 09/25/2021 |
| Protein Arginine Methyltransferase 1 Is Essential for the Meiosis of Male Germ Cells. | Protein Arginine Methyltransferase 1 Is Essential for the Meiosis of Male Germ Cells.
Waseem S, Kumar S, Lee K, Yoon BH, Kim M, Kim H, Lee K., Free PMC Article | 09/11/2021 |
| Loss of PRMT1 in the central nervous system (CNS) induces reactive astrocytes and microglia during postnatal brain development. | Loss of PRMT1 in the central nervous system (CNS) induces reactive astrocytes and microglia during postnatal brain development.
Hashimoto M, Kumabe A, Kim JD, Murata K, Sekizar S, Williams A, Lu W, Ishida J, Nakagawa T, Endo M, Minami Y, Fukamizu A. | 06/19/2021 |
| PRMT1-p53 Pathway Controls Epicardial EMT and Invasion. | PRMT1-p53 Pathway Controls Epicardial EMT and Invasion.
Jackson-Weaver O, Ungvijanpunya N, Yuan Y, Qian J, Gou Y, Wu J, Shen H, Chen Y, Li M, Richard S, Chai Y, Sucov HM, Xu J., Free PMC Article | 05/22/2021 |
| TC-E 5003, a protein methyltransferase 1 inhibitor, activates the PKA-dependent thermogenic pathway in primary murine and human subcutaneous adipocytes. | TC-E 5003, a protein methyltransferase 1 inhibitor, activates the PKA-dependent thermogenic pathway in primary murine and human subcutaneous adipocytes.
Park MJ, Liao J, Kim DI. | 05/15/2021 |
| A critical role for hepatic protein arginine methyltransferase 1 isoform 2 in glycemic control. | A critical role for hepatic protein arginine methyltransferase 1 isoform 2 in glycemic control.
Ma Y, Liu S, Jun H, Wang J, Fan X, Li G, Yin L, Rui L, Weinman SA, Gong J, Wu J., Free PMC Article | 05/1/2021 |
| Protein arginine methyltransferase-1 stimulates dopaminergic neuronal cell death in a Parkinson's disease model. | Protein arginine methyltransferase-1 stimulates dopaminergic neuronal cell death in a Parkinson's disease model.
Nho JH, Park MJ, Park HJ, Lee JH, Choi JH, Oh SJ, Lee YJ, Yu YB, Kim HS, Kim DI, Choi WS. | 02/27/2021 |
| Hepatocyte PRMT1 protects from alcohol induced liver injury by modulating oxidative stress responses. | Hepatocyte PRMT1 protects from alcohol induced liver injury by modulating oxidative stress responses.
Zhao J, Adams A, Weinman SA, Tikhanovich I., Free PMC Article | 10/24/2020 |
| PRMT1 suppresses ATF4-mediated endoplasmic reticulum response in cardiomyocytes. | PRMT1 suppresses ATF4-mediated endoplasmic reticulum response in cardiomyocytes.
Jeong MH, Jeong HJ, Ahn BY, Pyun JH, Kwon I, Cho H, Kang JS., Free PMC Article | 09/5/2020 |
| PRMT1 plays an essential role in maintaining beta-cell identity by regulating chromatin accessibility. | PRMT1 Is Required for the Maintenance of Mature β-Cell Identity.
Kim H, Yoon BH, Oh CM, Lee J, Lee K, Song H, Kim E, Yi K, Kim MY, Kim H, Kim YK, Seo EH, Heo H, Kim HJ, Lee J, Suh JM, Koo SH, Seong JK, Kim S, Ju YS, Shong M, Kim M, Kim H. | 08/12/2020 |