| Neuronal activity drives IGF2 expression from pericytes to form long-term memory. | Neuronal activity drives IGF2 expression from pericytes to form long-term memory.
Pandey K, Bessières B, Sheng SL, Taranda J, Osten P, Sandovici I, Constancia M, Alberini CM., | 12/21/2023 |
| IGF2 is upregulated by its antisense RNA to potentiate pancreatic cancer progression. | IGF2 is upregulated by its antisense RNA to potentiate pancreatic cancer progression.
Tian Y, Han W, Fu L, Zhang J, Zhou X. | 12/6/2023 |
| IGF2 deficiency promotes liver aging through mitochondrial dysfunction and upregulated CEBPB signaling in D-galactose-induced aging mice. | IGF2 deficiency promotes liver aging through mitochondrial dysfunction and upregulated CEBPB signaling in D-galactose-induced aging mice.
Zhou X, Tan B, Gui W, Zhou C, Zhao H, Lin X, Li H., Free PMC Article | 12/1/2023 |
| TMED10 mediates the trafficking of insulin-like growth factor 2 along the secretory pathway for myoblast differentiation. | TMED10 mediates the trafficking of insulin-like growth factor 2 along the secretory pathway for myoblast differentiation.
Li T, Yang F, Heng Y, Zhou S, Wang G, Wang J, Wang J, Chen X, Yao ZP, Wu Z, Guo Y., Free PMC Article | 11/28/2023 |
| Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition. | Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition.
Hao KL, Zhai QC, Gu Y, Chen YQ, Wang YN, Liu R, Yan SP, Wang Y, Shi YF, Lei W, Shen ZY, Xu Y, Hu SJ., | 09/12/2023 |
| Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma. | Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma.
Abril-Fornaguera J, Torrens L, Andreu-Oller C, Carrillo-Reixach J, Rialdi A, Balaseviciute U, Pinyol R, Montironi C, Haber PK, Del Río-Álvarez Á, Domingo-Sàbat M, Royo L, Akers NK, Willoughby CE, Peix J, Torres-Martin M, Puigvehi M, Cairo S, Childs M, Maibach R, Alaggio R, Czauderna P, Morland B, Losic B, Mazzaferro V, Guccione E, Sia D, Armengol C, Llovet JM., Free PMC Article | 08/11/2023 |
| Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene. | Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene.
Lopez-Tello J, Yong HEJ, Sandovici I, Dowsett GKC, Christoforou ER, Salazar-Petres E, Boyland R, Napso T, Yeo GSH, Lam BYH, Constancia M, Sferruzzi-Perri AN. | 07/17/2023 |
| Overexpression of IGF2 affects mouse weight and glycolipid metabolism and IGF2 is positively related to macrosomia. | Overexpression of IGF2 affects mouse weight and glycolipid metabolism and IGF2 is positively related to macrosomia.
Zhang Q, Qin S, Huai J, Yang H, Wei Y., Free PMC Article | 05/15/2023 |
| Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1-42 in Alzheimer's disease. | Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1-42 in Alzheimer's disease.
Fertan E, Gendron WH, Wong AA, Hanson GM, Brown RE, Weaver ICG., Free PMC Article | 02/11/2023 |
| IGF2 interacts with the imprinted gene Cdkn1c to promote terminal differentiation of neural stem cells. | IGF2 interacts with the imprinted gene Cdkn1c to promote terminal differentiation of neural stem cells.
Lozano-Ureña A, Lázaro-Carot L, Jiménez-Villalba E, Montalbán-Loro R, Mateos-White I, Duart-Abadía P, Martínez-Gurrea I, Nakayama KI, Fariñas I, Kirstein M, Gil-Sanz C, Ferrón SR., Free PMC Article | 02/10/2023 |
| Genetic ablation of the preptin-coding portion of Igf2 impairs pancreatic function in female mice. | Genetic ablation of the preptin-coding portion of Igf2 impairs pancreatic function in female mice.
Buckels EJ, Hsu HL, Buchanan CM, Matthews BG, Lee KL. | 12/17/2022 |
| Dysregulated H19/Igf2 expression disrupts cardiac-placental axis during development of Silver-Russell syndrome-like mouse models. | Dysregulated H19/Igf2 expression disrupts cardiac-placental axis during development of Silver-Russell syndrome-like mouse models.
Chang S, Fulmer D, Hur SK, Thorvaldsen JL, Li L, Lan Y, Rhon-Calderon EA, Leu NA, Chen X, Epstein JA, Bartolomei MS., Free PMC Article | 12/10/2022 |
| Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma. | Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma.
Kumar D, Das M, Oberg A, Sahoo D, Wu P, Sauceda C, Jih L, Ellies LG, Langiewicz MT, Sen S, Webster NJG., Free PMC Article | 08/6/2022 |
| Hepatic IGF2/H19 Epigenetic Alteration Induced Glucose Intolerance in Gestational Diabetes Mellitus Offspring via FoxO1 Mediation. | Hepatic IGF2/H19 Epigenetic Alteration Induced Glucose Intolerance in Gestational Diabetes Mellitus Offspring via FoxO1 Mediation.
Jiang Y, Zhu H, Chen Z, Yu YC, Guo XH, Chen Y, Yang MM, Chen BW, Sagnelli M, Xu D, Zhao BH, Luo Q., Free PMC Article | 04/23/2022 |
| Sequential activation of uterine epithelial IGF1R by stromal IGF1 and embryonic IGF2 directs normal uterine preparation for embryo implantation. | Sequential activation of uterine epithelial IGF1R by stromal IGF1 and embryonic IGF2 directs normal uterine preparation for embryo implantation.
Zhou C, Lv M, Wang P, Guo C, Ni Z, Bao H, Tang Y, Cai H, Lu J, Deng W, Yang X, Xia G, Wang H, Wang C, Kong S., Free PMC Article | 03/12/2022 |
| The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth. | The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth.
Sandovici I, Georgopoulou A, Pérez-García V, Hufnagel A, López-Tello J, Lam BYH, Schiefer SN, Gaudreau C, Santos F, Hoelle K, Yeo GSH, Burling K, Reiterer M, Fowden AL, Burton GJ, Branco CM, Sferruzzi-Perri AN, Constância M., Free PMC Article | 02/12/2022 |
| Paternal Exercise Improves the Metabolic Health of Offspring via Epigenetic Modulation of the Germline. | Paternal Exercise Improves the Metabolic Health of Offspring via Epigenetic Modulation of the Germline.
Costa-Júnior JM, Ferreira SM, Kurauti MA, Bernstein DL, Ruano EG, Kameswaran V, Schug J, Freitas-Dias R, Zoppi CC, Boschero AC, Oliveira CAM, Santos GJ, Carneiro EM, Kaestner KH., Free PMC Article | 02/5/2022 |
| Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes. | Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes.
Liao J, Zeng TB, Pierce N, Tran DA, Singh P, Mann JR, Szabó PE., Free PMC Article | 01/22/2022 |
| Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation. | Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation.
Wu HY, Cheng Y, Jin LY, Zhou Y, Pang HY, Zhu H, Yan CC, Yan YS, Yu JE, Sheng JZ, Huang HF. | 12/4/2021 |
| Per1/Per2-Igf2 axis-mediated circadian regulation of myogenic differentiation. | Per1/Per2-Igf2 axis-mediated circadian regulation of myogenic differentiation.
Katoku-Kikyo N, Paatela E, Houtz DL, Lee B, Munson D, Wang X, Hussein M, Bhatia J, Lim S, Yuan C, Asakura Y, Asakura A, Kikyo N., Free PMC Article | 10/9/2021 |
| Biochemical evaluation of intracerebroventricular rhNAGLU-IGF2 enzyme replacement therapy in neonatal mice with Sanfilippo B syndrome. | Biochemical evaluation of intracerebroventricular rhNAGLU-IGF2 enzyme replacement therapy in neonatal mice with Sanfilippo B syndrome.
Kan SH, Elsharkawi I, Le SQ, Prill H, Mangini L, Cooper JD, Lawrence R, Sands MS, Crawford BE, Dickson PI., Free PMC Article | 09/11/2021 |
| The ER Chaperones BiP and Grp94 Regulate the Formation of Insulin-Like Growth Factor 2 (IGF2) Oligomers. | The ER Chaperones BiP and Grp94 Regulate the Formation of Insulin-Like Growth Factor 2 (IGF2) Oligomers.
Jin Y, Kotler JLM, Wang S, Huang B, Halpin JC, Street TO., Free PMC Article | 08/28/2021 |
| Paternal systemic inflammation induces offspring programming of growth and liver regeneration in association with Igf2 upregulation. | Paternal systemic inflammation induces offspring programming of growth and liver regeneration in association with Igf2 upregulation.
Zhang Z, Zhao Y, Zhang Y, Zhao R, He B. | 07/3/2021 |
| Sex-differences in echocardiographic assessment of aortic valve in young adult LDLr(-/-)/ApoB(100/100)/IGF-II(+/-) mice. | Sex-differences in echocardiographic assessment of aortic valve in young adult LDLr(-/-)/ApoB(100/100)/IGF-II(+/-) mice.
Annabi MS, Clisson M, Fleury MA, Voisine M, Hervault M, Shen M, Boilard AJ, Marette A, Ong G, Côté N, Clavel MA. | 05/8/2021 |
| The developmental and experience-dependent expression of IGF-2 in mice visual cortex. | The developmental and experience-dependent expression of IGF-2 in mice visual cortex.
Luo Y, Liu Z, Luo S, Wang X, Tao L. | 04/24/2021 |