| Molecular Mechanisms of IL18 in Disease. | Molecular Mechanisms of IL18 in Disease.
Yamanishi K, Hata M, Gamachi N, Watanabe Y, Yamanishi C, Okamura H, Matsunaga H., Free PMC Article | 01/9/2024 |
| Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer. | Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer.
Suzuki T, Boonyaleka K, Okano T, Iida T, Yoshida M, Fukano H, Hoshino Y, Iwakura Y, Ablordey AS, Ashida H., Free PMC Article | 11/3/2023 |
| IL-18 serves as a main effector of CAF-derived METTL3 against immunosuppression of NSCLC via driving NF-kappaB pathway. | IL-18 serves as a main effector of CAF-derived METTL3 against immunosuppression of NSCLC via driving NF-κB pathway.
Xu L, Li K, Li J, Xu F, Liang S, Kong Y, Chen B., Free PMC Article | 10/28/2023 |
| CSF-1R+ Macrophages Control the Gut Microbiome-Enhanced Liver Invariant NKT Function through IL-18. | CSF-1R+ Macrophages Control the Gut Microbiome-Enhanced Liver Invariant NKT Function through IL-18.
Ma C, McCallen J, McVey JC, Trehan R, Bauer K, Zhang Q, Ruf B, Wang S, Lai CW, Trinchieri G, Berzofsky JA, Korangy F, Greten TF., | 09/21/2023 |
| NLRP3 inflammasome-driven IL-1beta and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy. | NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy.
Fujimura K, Karasawa T, Komada T, Yamada N, Mizushina Y, Baatarjav C, Matsumura T, Otsu K, Takeda N, Mizukami H, Kario K, Takahashi M. | 06/15/2023 |
| Interleukin-18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. | Interleukin-18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis.
Knorr J, Kaufmann B, Inzaugarat ME, Holtmann TM, Geisler L, Hundertmark J, Kohlhepp MS, Boosheri LM, Chilin-Fuentes DR, Birmingham A, Fisch KM, Schilling JD, Loosen SH, Trautwein C, Roderburg C, Demir M, Tacke F, Hoffman HM, Feldstein AE, Wree A., Free PMC Article | 05/18/2023 |
| Wnt3a/YTHDF1 Regulated Oxaliplatin-Induced Neuropathic Pain Via TNF-alpha/IL-18 Expression in the Spinal Cord. | Wnt3a/YTHDF1 Regulated Oxaliplatin-Induced Neuropathic Pain Via TNF-α/IL-18 Expression in the Spinal Cord.
Bai X, Huang Y, Huang W, Zhang Y, Zhang K, Li Y, Ouyang H. | 04/10/2023 |
| IL-18-mediated neutrophil recruitment promotes acute lung injury in inflammation-mediated chronic pancreatitis. | IL-18-mediated neutrophil recruitment promotes acute lung injury in inflammation-mediated chronic pancreatitis.
Kandikattu HK, Upparahalli Venkateshaiah S, Kumar S, Yadavalli CS, Mishra A. | 03/7/2023 |
| Klebsiella pneumoniae Induces Inflammatory Bowel Disease Through Caspase-11-Mediated IL18 in the Gut Epithelial Cells. | Klebsiella pneumoniae Induces Inflammatory Bowel Disease Through Caspase-11-Mediated IL18 in the Gut Epithelial Cells.
Zhang Q, Su X, Zhang C, Chen W, Wang Y, Yang X, Liu D, Zhang Y, Yang R., Free PMC Article | 02/23/2023 |
| IL-18 maintains the homeostasis of mucosal immune system via inflammasome-independent but microbiota-dependent manner. | IL-18 maintains the homeostasis of mucosal immune system via inflammasome-independent but microbiota-dependent manner.
Zheng X, Liu L, Meng G, Zhu S, Zhou R, Jiang W. | 01/28/2023 |
| HMGB1 Promotes In Vitro and In Vivo Skeletal Muscle Atrophy through an IL-18-Dependent Mechanism. | HMGB1 Promotes In Vitro and In Vivo Skeletal Muscle Atrophy through an IL-18-Dependent Mechanism.
Ho TL, Tang CH, Chang SL, Tsai CH, Chen HT, Su CM., Free PMC Article | 12/31/2022 |
| Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulation. | Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulation.
Zhang X, Luo S, Wang M, Cao Q, Zhang Z, Huang Q, Li J, Deng Z, Liu T, Liu CL, Meppen M, Vromman A, Flavell RA, Hotamışlıgil GS, Liu J, Libby P, Liu Z, Shi GP., Free PMC Article | 12/31/2022 |
| Excessive IL-10 and IL-18 trigger hemophagocytic lymphohistiocytosis-like hyperinflammation and enhanced myelopoiesis. | Excessive IL-10 and IL-18 trigger hemophagocytic lymphohistiocytosis-like hyperinflammation and enhanced myelopoiesis.
Tang Y, Xu Q, Luo H, Yan X, Wang G, Hu L, Jin J, Witte DP, Marsh RA, Huang L, Huang G, Zhou J., Free PMC Article | 11/12/2022 |
| IL-18/IL-18R Signaling Is Dispensable for ILC Development But Constrains the Growth of ILCP/ILCs. | IL-18/IL-18R Signaling Is Dispensable for ILC Development But Constrains the Growth of ILCP/ILCs.
Xie M, Zhang M, Dai M, Yue S, Li Z, Qiu J, Lu C, Xu W., Free PMC Article | 08/6/2022 |
| Role of IL-18-transformed CD274-expressing eosinophils in promoting airway obstruction in experimental asthma. | Role of IL-18-transformed CD274-expressing eosinophils in promoting airway obstruction in experimental asthma.
Mishra A, Majid D, Kandikattu HK, Yadavalli CS, Upparahalli Venkateshaiah S., Free PMC Article | 07/23/2022 |
| IL18 signaling causes islet beta cell development and insulin secretion via different receptors on acinar and beta cells. | IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells.
Zhang X, Luo S, Wang M, Huang Q, Fang W, Li J, Liu T, Zhang Y, Deng Z, Liu CL, Guan S, Ayala JE, Flavell RA, Kulkarni RN, Libby P, Guo J, Liu Z, Shi GP., Free PMC Article | 07/2/2022 |
| The Proinflammatory Cytokines IL-18, IL-21, and IFN-gamma Differentially Regulate Liver Inflammation and Anti-Mitochondrial Antibody Level in a Murine Model of Primary Biliary Cholangitis. | The Proinflammatory Cytokines IL-18, IL-21, and IFN-γ Differentially Regulate Liver Inflammation and Anti-Mitochondrial Antibody Level in a Murine Model of Primary Biliary Cholangitis.
Xu YF, Yao Y, Ma M, Yang SH, Jiang P, Wang J, Tsuneyama K, Wang C, Liu X, Li L, Lian ZX., Free PMC Article | 04/16/2022 |
| Long Non-Coding RNA NEAT1 Knockdown Alleviates Rheumatoid Arthritis by Reducing IL-18 through p300/CBP Repression. | Long Non-Coding RNA NEAT1 Knockdown Alleviates Rheumatoid Arthritis by Reducing IL-18 through p300/CBP Repression.
Guo T, Xing Y, Chen Z, Zhu H, Yang L, Xiao Y, Xu J. | 03/26/2022 |
| Interleukin-1beta secretion induced by mucosa-associated gut commensal bacteria promotes intestinal barrier repair. | Interleukin-1β secretion induced by mucosa-associated gut commensal bacteria promotes intestinal barrier repair.
Wu WH, Kim M, Chang LC, Assie A, Saldana-Morales FB, Zegarra-Ruiz DF, Norwood K, Samuel BS, Diehl GE., Free PMC Article | 02/26/2022 |
| Lactobacillus casei ATCC 393 and it's metabolites alleviate dextran sulphate sodium-induced ulcerative colitis in mice through the NLRP3-(Caspase-1)/IL-1beta pathway. | Lactobacillus casei ATCC 393 and it's metabolites alleviate dextran sulphate sodium-induced ulcerative colitis in mice through the NLRP3-(Caspase-1)/IL-1β pathway.
Dou X, Qiao L, Chang J, Yan S, Song X, Chen Y, Xu Q, Xu C. | 02/12/2022 |
| Exploring Molecular Mechanisms Involved in the Development of the Depression-Like Phenotype in Interleukin-18-Deficient Mice. | Exploring Molecular Mechanisms Involved in the Development of the Depression-Like Phenotype in Interleukin-18-Deficient Mice.
Yamanishi K, Miyauchi M, Mukai K, Hashimoto T, Uwa N, Seino H, Li W, Gamachi N, Hata M, Kuwahara-Otani S, Maeda S, Watanabe Y, Yamanishi H, Yagi H, Okamura H, Matsunaga H., Free PMC Article | 01/29/2022 |
| IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice. | IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice.
Thomas JM, Ling YH, Huuskes B, Jelinic M, Sharma P, Saini N, Ferens DM, Diep H, Krishnan SM, Kemp-Harper BK, O'Connor PM, Latz E, Arumugam TV, Guzik TJ, Hickey MJ, Mansell A, Sobey CG, Vinh A, Drummond GR. | 01/22/2022 |
| Interleukin-18: A Novel Participant in the Occurrence, Development, and Drug Therapy of Obliterative Bronchiolitis Postlung Transplantation. | Interleukin-18: A Novel Participant in the Occurrence, Development, and Drug Therapy of Obliterative Bronchiolitis Postlung Transplantation.
Shu P, Zhang W, Zhang Y, Zhao Y, Li Y, Zhang X., Free PMC Article | 01/8/2022 |
| MAP3K2 augments Th1 cell differentiation via IL-18 to promote T cell-mediated colitis. | MAP3K2 augments Th1 cell differentiation via IL-18 to promote T cell-mediated colitis.
Wu N, Chen D, Sun H, Tan J, Zhang Y, Zhang T, Han Y, Liu H, Ouyang X, Yang XD, Niu X, Zhong J, Wang Z, Su B. | 01/1/2022 |
| Protective role of IL-18 in host defenses against group B Streptococcus. | Protective role of IL-18 in host defenses against group B Streptococcus.
Mancuso G, Midiri A, Beninati C, Zummo S, Biondo C. | 12/25/2021 |