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    Il9 interleukin 9 [ Mus musculus (house mouse) ]

    Gene ID: 16198, updated on 4-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    p40 homodimers bridge ischemic tissue inflammation and heterologous alloimmunity in mice via IL-15 transpresentation.

    p40 homodimers bridge ischemic tissue inflammation and heterologous alloimmunity in mice via IL-15 transpresentation.
    Tsuda H, Keslar KS, Baldwin WM 3rd, Heeger PS, Valujskikh A, Fairchild RL., Free PMC Article

    03/19/2024
    Interleukin-9 production by type 2 innate lymphoid cells induces Paneth cell metaplasia and small intestinal remodeling.

    Interleukin-9 production by type 2 innate lymphoid cells induces Paneth cell metaplasia and small intestinal remodeling.
    Yuan C, Rayasam A, Moe A, Hayward M, Wells C, Szabo A, Mackenzie A, Salzman N, Drobyski WR., Free PMC Article

    12/5/2023
    DUSP8 induces TGF-beta-stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-alpha.

    DUSP8 induces TGF-β-stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-α.
    Chuang HC, Hsueh CH, Hsu PM, Tsai CY, Shih YC, Chiu HY, Chen YM, Yu WK, Chen MH, Tan TH., Free PMC Article

    11/3/2023
    IL-9 promotes methicillin-resistant Staphylococcus aureus pneumonia by regulating the polarization and phagocytosis of macrophages.

    IL-9 promotes methicillin-resistant Staphylococcus aureus pneumonia by regulating the polarization and phagocytosis of macrophages.
    Xu W, Tian K, Hu S, Chen M, Zhang M., Free PMC Article

    11/1/2023
    IL9 Polarizes Macrophages to M1 and Induces the Infiltration of Antitumor Immune Cells via MIP-1 and CXCR3 Chemokines.

    IL9 Polarizes Macrophages to M1 and Induces the Infiltration of Antitumor Immune Cells via MIP-1 and CXCR3 Chemokines.
    Do-Thi VA, Park SM, Park SM, Jeong HJ, Cho G, An HJ, Kim YS, Lee H, Lee JO., Free PMC Article

    08/10/2023
    Mechanistic insight of interleukin-9 induced osteoclastogenesis.

    Mechanistic insight of interleukin-9 induced osteoclastogenesis.
    Chakraborty S, Schneider J, Mitra DK, Kubatzky KF.

    06/16/2023
    JAKing up IL-9 expression in TH9 cells.

    JAKing up IL-9 expression in T(H)9 cells.
    Muñoz-Paleta O, Licona-Limón P.

    06/5/2023
    ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of Il9 during Allergic Lung Inflammation.

    ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of Il9 during Allergic Lung Inflammation.
    Kharwadkar R, Ulrich BJ, Chu M, Koh B, Hufford MM, Fu Y, Birdsey GM, Porse BT, Randi AM, Kaplan MH., Free PMC Article

    03/11/2023
    IL-4 receptor alpha signaling alters oral food challenge and immunotherapy outcomes in mice.

    IL-4 receptor alpha signaling alters oral food challenge and immunotherapy outcomes in mice.
    Ganesan V, Sharma A, Tomar S, Schuler CF 4th, Hogan SP.

    01/28/2023
    IL-9 stimulates an anti-tumor immune response and facilitates immune checkpoint blockade in the CMT167 mouse model.

    IL-9 stimulates an anti-tumor immune response and facilitates immune checkpoint blockade in the CMT167 mouse model.
    Feng Y, Yan S, Lam SK, Ko FCF, Chen C, Khan M, Ho JC.

    01/11/2023
    IL-9 plays a protective role on host defense against the infection of Cryptococcus neoformans.

    IL-9 plays a protective role on host defense against the infection of Cryptococcus neoformans.
    Xu J, Liu H, Liu F, Luo Y, Yang R, Kong Q, Sang H.

    11/19/2022
    IL-9/STAT3/fatty acid oxidation-mediated lipid peroxidation contributes to Tc9 cell longevity and enhanced antitumor activity.

    IL-9/STAT3/fatty acid oxidation-mediated lipid peroxidation contributes to Tc9 cell longevity and enhanced antitumor activity.
    Xiao L, Ma X, Ye L, Su P, Xiong W, Bi E, Wang Q, Xian M, Yang M, Qian J, Yi Q., Free PMC Article

    04/9/2022
    Kidney VISTA prevents IFN-gamma/IL-9 axis-mediated tubulointerstitial fibrosis after acute glomerular injury.

    Kidney VISTA prevents IFN-γ/IL-9 axis-mediated tubulointerstitial fibrosis after acute glomerular injury.
    Kim MG, Yun D, Kang CL, Hong M, Hwang J, Moon KC, Jeong CW, Kwak C, Kim DK, Oh KH, Joo KW, Kim YS, Lee DS, Han SS., Free PMC Article

    02/19/2022
    Interleukin-9 deficiency affects lipopolysaccharide-induced macrophage-related oxidative stress and myocardial cell apoptosis via the Nrf2 pathway both in vivo and in vitro.

    Interleukin-9 deficiency affects lipopolysaccharide-induced macrophage-related oxidative stress and myocardial cell apoptosis via the Nrf2 pathway both in vivo and in vitro.
    Liang Z, Pan F, Yang Z, Wang M, Hu C, Shi L, Ji Q, Liu L.

    01/8/2022
    Interleukin-9 in Immunopathology of Trypanosoma cruzi Experimental Infection.

    Interleukin-9 in Immunopathology of Trypanosoma cruzi Experimental Infection.
    Silva NSL, Orikaza CM, de Santana FR, Dos Santos LA, Salu BR, Oliva MLV, Sinigaglia RC, Mortara RA., Free PMC Article

    12/11/2021
    T-bet and STAT6 Coordinately Suppress the Development of IL-9-Mediated Atopic Dermatitis-Like Skin Inflammation in Mice.

    T-bet and STAT6 Coordinately Suppress the Development of IL-9-Mediated Atopic Dermatitis-Like Skin Inflammation in Mice.
    Makita S, Takatori H, Matsuki A, Kawashima H, Iwata A, Tanaka S, Nakagomi D, Oya Y, Matsumura R, Tamachi T, Suto A, Suzuki K, Hirose K, Nakajima H.

    11/22/2021
    IL-9 contributes to the host immune response against Helicobacter pylori and helps limit infection in a Mouse Model.

    IL-9 contributes to the host immune response against Helicobacter pylori and helps limit infection in a Mouse Model.
    He Y, Ning J, Li B, Guo H, Hao N, Wu C.

    10/23/2021
    IL-9: a novel pro-podocyte survival cytokine in FSGS.

    IL-9: a novel pro-podocyte survival cytokine in FSGS.
    Lin Q, Menon MC, He JC.

    08/14/2021
    IL-4-BATF signaling directly modulates IL-9 producing mucosal mast cell (MMC9) function in experimental food allergy.

    IL-4-BATF signaling directly modulates IL-9 producing mucosal mast cell (MMC9) function in experimental food allergy.
    Tomar S, Ganesan V, Sharma A, Zeng C, Waggoner L, Smith A, Kim CH, Licona-Limón P, Reinhardt RL, Flavell RA, Wang YH, Hogan SP., Free PMC Article

    07/31/2021
    Interleukin-9 Aggravates Isoproterenol-Induced Heart Failure by Activating Signal Transducer and Activator of Transcription 3 Signalling.

    Interleukin-9 Aggravates Isoproterenol-Induced Heart Failure by Activating Signal Transducer and Activator of Transcription 3 Signalling.
    Yang Y, Xu C, Tang S, Xia Z.

    05/22/2021
    Inhibitory effect of activin A on IL-9 production by mouse NK cells through Smad3 signaling.

    Inhibitory effect of activin A on IL-9 production by mouse NK cells through Smad3 signaling.
    Ma C, Qi Y, Liu H, Wu C, Cui X, Liu Z.

    04/13/2021
    Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity.

    Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity.
    Almeida RR, Vieira RS, Castoldi A, Terra FF, Melo ACL, Canesso MCC, Lemos L, Cipelli M, Rana N, Hiyane MI, Pearce EL, Martins FDS, Faria AMC, Câmara NOS., Free PMC Article

    02/27/2021
    IL-33 induced airways inflammation is partially dependent on IL-9.

    IL-33 induced airways inflammation is partially dependent on IL-9.
    Du X, Li C, Wang W, Huang Q, Wang J, Tong Z, Huang K, Chen Y, Yuan H, Lv Z, Corrigan CJ, Wang W, Ying S.

    01/9/2021
    IL-9 exerts biological function on antigen-experienced murine T cells and exacerbates colitis induced by adoptive transfer.

    IL-9 exerts biological function on antigen-experienced murine T cells and exacerbates colitis induced by adoptive transfer.
    de Heusch M, Steenwinckel V, Cochez PM, Louahed J, Warnier G, Lemaire MM, Renauld JC, Dumoutier L.

    12/12/2020
    Interleukin-9 Inhibits Lung Metastasis of Melanoma through Stimulating Anti-Tumor M1 Macrophages.

    Interleukin-9 Inhibits Lung Metastasis of Melanoma through Stimulating Anti-Tumor M1 Macrophages.
    Park SM, Do-Thi VA, Lee JO, Lee H, Kim YS., Free PMC Article

    11/21/2020
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