U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Itgb2 integrin beta 2 [ Mus musculus (house mouse) ]

    Gene ID: 16414, updated on 5-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    B-cell receptor associated protein 31 deficiency decreases the expression of adhesion molecule CD11b/CD18 and PSGL-1 in neutrophils to ameliorate acute lung injury.

    B-cell receptor associated protein 31 deficiency decreases the expression of adhesion molecule CD11b/CD18 and PSGL-1 in neutrophils to ameliorate acute lung injury.
    Li GX, Jiang XH, Zang JN, Zhu BZ, Jia CC, Niu KW, Liu X, Jiang R, Wang B., Free PMC Article

    11/15/2023
    Distinct bidirectional regulation of LFA1 and alpha4beta7 by Rap1 and integrin adaptors in T cells under shear flow.

    Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow.
    Kamioka Y, Ueda Y, Kondo N, Tokuhiro K, Ikeda Y, Bergmeier W, Kinashi T., Free PMC Article

    10/12/2023
    LFA-1 knockout inhibited the tumor growth and is correlated with treg cells.

    LFA-1 knockout inhibited the tumor growth and is correlated with treg cells.
    Niu T, Li Z, Huang Y, Ye Y, Liu Y, Ye Z, Jiang L, He X, Wang L, Li J., Free PMC Article

    09/28/2023
    LFA-1/ICAM-1 Adhesion Pathway Mediates the Homeostatic Migration of Lymphocytes from Peripheral Tissues into Lymph Nodes through Lymphatic Vessels.

    LFA-1/ICAM-1 Adhesion Pathway Mediates the Homeostatic Migration of Lymphocytes from Peripheral Tissues into Lymph Nodes through Lymphatic Vessels.
    Guo J, Xu Z, Gunderson RC, Xu B, Michie SA., Free PMC Article

    08/28/2023
    Endothelial CCRL2 induced by disturbed flow promotes atherosclerosis via chemerin-dependent beta2 integrin activation in monocytes.

    Endothelial CCRL2 induced by disturbed flow promotes atherosclerosis via chemerin-dependent β2 integrin activation in monocytes.
    Tang C, Chen G, Wu F, Cao Y, Yang F, You T, Liu C, Li M, Hu S, Ren L, Lu Q, Deng W, Xu Y, Wang G, Jo H, Zhang Y, Wu Y, Zabel BA, Zhu L.,

    08/9/2023
    Cutting Edge: Optimal Formation of Hepatic Tissue-Resident Memory CD4 T Cells Requires T-bet Regulation of CD18.

    Cutting Edge: Optimal Formation of Hepatic Tissue-Resident Memory CD4 T Cells Requires T-bet Regulation of CD18.
    Depew CE, Nguyen AT, Franke MC, Calderon J, Sciammas R, McSorley SJ.,

    07/6/2023
    Regulation of CD18 stability by SIGIRR-modulated ubiquitination: new insights into the relationship between innate immune response and acute lung injury.

    Regulation of CD18 stability by SIGIRR-modulated ubiquitination: new insights into the relationship between innate immune response and acute lung injury.
    Tian F, Lei J, Ni Y, Zhong D, Xie N, Ma J, Wang H, Si S, Wu Y, Jiang T.

    05/18/2023
    The Role of LFA-1 for the Differentiation and Function of Regulatory T Cells-Lessons Learned from Different Transgenic Mouse Models.

    The Role of LFA-1 for the Differentiation and Function of Regulatory T Cells-Lessons Learned from Different Transgenic Mouse Models.
    Klaus T, Wilson A, Fichter M, Bros M, Bopp T, Grabbe S., Free PMC Article

    04/14/2023
    CD18 controls the development and activation of monocyte-to-macrophage axis during chronic schistosomiasis.

    CD18 controls the development and activation of monocyte-to-macrophage axis during chronic schistosomiasis.
    Souza COS, Elias-Oliveira J, Pastore MR, Fontanari C, Rodrigues VF, Rodriguez V, Gardinassi LG, Faccioli LH., Free PMC Article

    10/29/2022
    LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model.

    LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model.
    Gao N, Wang C, Yu Y, Xie L, Xing Y, Zhang Y, Wang Y, Wu J, Cai Y., Free PMC Article

    10/29/2022
    The role of beta2 integrin in dendritic cell migration during infection.

    The role of β(2) integrin in dendritic cell migration during infection.
    Altorki T, Muller W, Brass A, Cruickshank S., Free PMC Article

    12/11/2021
    Bactericidal/Permeability-Increasing Protein Preeminently Mediates Clearance of Pseudomonas aeruginosa In Vivo via CD18-Dependent Phagocytosis.

    Bactericidal/Permeability-Increasing Protein Preeminently Mediates Clearance of Pseudomonas aeruginosa In Vivo via CD18-Dependent Phagocytosis.
    Theprungsirikul J, Skopelja-Gardner S, Burns AS, Wierzbicki RM, Rigby WFC., Free PMC Article

    10/23/2021
    Role of LFA-1 integrin in the control of a lymphocytic choriomeningitis virus (LCMV) infection.

    Role of LFA-1 integrin in the control of a lymphocytic choriomeningitis virus (LCMV) infection.
    Perro M, Iannacone M, von Andrian UH, Peixoto A., Free PMC Article

    09/18/2021
    Platelet and Erythrocyte Extravasation across Inflamed Corneal Venules Depend on CD18, Neutrophils, and Mast Cell Degranulation.

    Platelet and Erythrocyte Extravasation across Inflamed Corneal Venules Depend on CD18, Neutrophils, and Mast Cell Degranulation.
    De La Cruz A, Hargrave A, Magadi S, Courson JA, Landry PT, Zhang W, Lam FW, Bray MA, Smith CW, Burns AR, Rumbaut RE., Free PMC Article

    08/21/2021
    LFA-1 signals to promote actin polymerization and upstream migration in T cells.

    LFA-1 signals to promote actin polymerization and upstream migration in T cells.
    Roy NH, Kim SHJ, Buffone A Jr, Blumenthal D, Huang B, Agarwal S, Schwartzberg PL, Hammer DA, Burkhardt JK., Free PMC Article

    07/3/2021
    Frontline Science: The expression of integrin alphaD beta2 (CD11d/CD18) on neutrophils orchestrates the defense mechanism against endotoxemia and sepsis.

    Frontline Science: The expression of integrin α(D) β(2) (CD11d/CD18) on neutrophils orchestrates the defense mechanism against endotoxemia and sepsis.
    Bailey WP, Cui K, Ardell CL, Keever KR, Singh S, Rodriguez-Gil DJ, Ozment TR, Williams DL, Yakubenko VP., Free PMC Article

    05/8/2021
    A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye.

    A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye.
    Hsueh PY, Ju Y, Vega A, Edman MC, MacKay JA, Hamm-Alvarez SF., Free PMC Article

    02/13/2021
    The proline-rich tyrosine kinase Pyk2 modulates integrin-mediated neutrophil adhesion and reactive oxygen species generation.

    The proline-rich tyrosine kinase Pyk2 modulates integrin-mediated neutrophil adhesion and reactive oxygen species generation.
    Canino J, Guidetti GF, Galgano L, Vismara M, Minetti G, Torti M, Canobbio I.

    12/12/2020
    Type I Collagen Signaling Regulates Opposing Fibrotic Pathways through alpha2beta1 Integrin.

    Type I Collagen Signaling Regulates Opposing Fibrotic Pathways through α(2)β(1) Integrin.
    Agarwal M, Goheen M, Jia S, Ling S, White ES, Kim KK., Free PMC Article

    12/12/2020
    LFA-1 Controls Th1 and Th17 Motility Behavior in the Inflamed Central Nervous System.

    LFA-1 Controls Th1 and Th17 Motility Behavior in the Inflamed Central Nervous System.
    Dusi S, Angiari S, Pietronigro EC, Lopez N, Angelini G, Zenaro E, Della Bianca V, Tosadori G, Paris F, Amoruso A, Carlucci T, Constantin G, Rossi B., Free PMC Article

    11/21/2020
    Frontline Science: Kindlin-3 is essential for patrolling and phagocytosis functions of nonclassical monocytes during metastatic cancer surveillance.

    Frontline Science: Kindlin-3 is essential for patrolling and phagocytosis functions of nonclassical monocytes during metastatic cancer surveillance.
    Marcovecchio PM, Zhu YP, Hanna RN, Dinh HQ, Tacke R, Wu R, McArdle S, Reynolds S, Araujo DJ, Ley K, Hedrick CC., Free PMC Article

    11/21/2020
    Differential nanoscale organisation of LFA-1 modulates T-cell migration.

    Differential nanoscale organisation of LFA-1 modulates T-cell migration.
    Shannon MJ, Pineau J, Griffié J, Aaron J, Peel T, Williamson DJ, Zamoyska R, Cope AP, Cornish GH, Owen DM., Free PMC Article

    09/26/2020
    Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity.

    Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity.
    Camponeschi A, Gerasimcik N, Wang Y, Fredriksson T, Chen D, Farroni C, Thorarinsdottir K, Sjökvist Ottsjö L, Aranburu A, Cardell S, Carsetti R, Gjertsson I, Mårtensson IL, Grimsholm O., Free PMC Article

    09/26/2020
    A beta2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation.

    A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation.
    Guenther C, Faisal I, Uotila LM, Asens ML, Harjunpää H, Savinko T, Öhman T, Yao S, Moser M, Morris SW, Tojkander S, Fagerholm SC., Free PMC Article

    08/22/2020
    CD18 inhibits progression of kidney cancer by down-regulating Treg cell levels.

    CD18 inhibits progression of kidney cancer by down-regulating Treg cell levels.
    Fu JH, Zhou CC, Mu HQ, Nan CJ, Li S, Lu DQ.

    08/15/2020
    firstprevious page of 8 nextlast