Galectin-3 and Autophagy in Renal Acute Tubular Necrosis. | Galectin-3 and Autophagy in Renal Acute Tubular Necrosis. Al-Salam S, Jagadeesh GS, Sudhadevi M, Yasin J., Free PMC Article | 04/17/2024 |
Novel pathogenic role for galectin-3 in early disease stages of arrhythmogenic cardiomyopathy. | Novel pathogenic role for galectin-3 in early disease stages of arrhythmogenic cardiomyopathy. Cason M, Celeghin R, Marinas MB, Beffagna G, Della Barbera M, Rizzo S, Remme CA, Bezzina CR, Tiso N, Bauce B, Thiene G, Basso C, Pilichou K. | 03/21/2024 |
Injured sensory neurons-derived galectin-3 contributes to neuropathic pain via programming microglia in the spinal dorsal horn. | Injured sensory neurons-derived galectin-3 contributes to neuropathic pain via programming microglia in the spinal dorsal horn. Shan L, Xu K, Ji L, Zeng Q, Liu Y, Wu Y, Chen Y, Li Y, Hu Q, Wu J, Xu Y, Luo Y, Li C, Wu C, Jiang C, Wang Z. | 03/4/2024 |
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. | Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. Yu C, Lad EM, Mathew R, Shiraki N, Littleton S, Chen Y, Hou J, Schlepckow K, Degan S, Chew L, Amason J, Kalnitsky J, Bowes Rickman C, Proia AD, Colonna M, Haass C, Saban DR., | 03/1/2024 |
Galectin-3 Cooperates with CD47 to Suppress Phagocytosis and T-cell Immunity in Gastric Cancer Peritoneal Metastases. | Galectin-3 Cooperates with CD47 to Suppress Phagocytosis and T-cell Immunity in Gastric Cancer Peritoneal Metastases. Fan Y, Song S, Li Y, Dhar SS, Jin J, Yoshimura K, Yao X, Wang R, Scott AW, Pizzi MP, Wu J, Ma L, Calin GA, Hanash S, Wang L, Curran M, Ajani JA., | 02/13/2024 |
Transcriptional upregulation of galectin-3 in multiple sclerosis. | Transcriptional upregulation of galectin-3 in multiple sclerosis. Mangano K, Petralia MC, Bella R, Pennisi M, Muñoz-Valle JF, Hernández-Bello J, Nicoletti F, Fagone P., Free PMC Article | 11/27/2023 |
Galectin-3 contributes to acute cardiac dysfunction and toxicity by increasing oxidative stress and fibrosis in doxorubicin-treated mice. | Galectin-3 contributes to acute cardiac dysfunction and toxicity by increasing oxidative stress and fibrosis in doxorubicin-treated mice. Seropian IM, Fontana Estevez FS, Villaverde A, Cacciagiú L, Bustos R, Touceda V, Penas F, Selser C, Morales C, Miksztowicz V, González GE. | 11/3/2023 |
Galectin-3 Mediates Vascular Dysfunction in Obesity by Regulating NADPH Oxidase 1. | Galectin-3 Mediates Vascular Dysfunction in Obesity by Regulating NADPH Oxidase 1. Padgett CA, Bátori RK, Speese AC, Rosewater CL, Bush WB, Derella CC, Haigh SB, Sellers HG, Corley ZL, West MA, Mintz JD, Ange BB, Harris RA, Brands MW, Fulton DJR, Stepp DW., | 10/28/2023 |
Co-expression of galectin-3 and vimentin in triple negative breast cancer cells promotes tumor progression, metastasis and survival. | Co-expression of galectin-3 and vimentin in triple negative breast cancer cells promotes tumor progression, metastasis and survival. Jeethy Ram T, Lekshmi A, Darvin P, Rajappan P, Jagathnath Krishna KM, Anoop TM, Augustine P, Mathew AP, Cherian K, Bhargavan RV, Somanathan T, Radhakrishna Pillai M, Santhosh Kumar TR, Sujathan K. | 08/19/2023 |
Galectin-3 activates spinal microglia to induce inflammatory nociception in wild type but not in mice modelling Alzheimer's disease. | Galectin-3 activates spinal microglia to induce inflammatory nociception in wild type but not in mice modelling Alzheimer's disease. Sideris-Lampretsas G, Oggero S, Zeboudj L, Silva R, Bajpai A, Dharmalingam G, Collier DA, Malcangio M., Free PMC Article | 06/28/2023 |
Elevated Galectin-3 Is Associated with Aging, Multiple Sclerosis, and Oxidized Phosphatidylcholine-Induced Neurodegeneration. | Elevated Galectin-3 Is Associated with Aging, Multiple Sclerosis, and Oxidized Phosphatidylcholine-Induced Neurodegeneration. Xue S, Lozinski BM, Ghorbani S, Ta K, D'Mello C, Yong VW, Dong Y., Free PMC Article | 06/28/2023 |
Amyloid beta oligomer promotes microglial galectin-3 and astrocytic lipocalin-2 levels in the hippocampus of mice fed a high-fat diet. | Amyloid β oligomer promotes microglial galectin-3 and astrocytic lipocalin-2 levels in the hippocampus of mice fed a high-fat diet. Shin HJ, Kim KE, Jeong EA, An HS, Lee SJ, Lee J, Roh GS. | 06/15/2023 |
Galectin-3 Mediates NETosis and Acts as an Autoantigen in Systemic Lupus Erythematosus-Associated Diffuse Alveolar Haemorrhage. | Galectin-3 Mediates NETosis and Acts as an Autoantigen in Systemic Lupus Erythematosus-Associated Diffuse Alveolar Haemorrhage. Chen SY, Wang CT, Chen CY, Kuo PY, Wang CR, Shiau AL, Chang CH, Wu CL., Free PMC Article | 06/13/2023 |
Role of galectin-3 in cardiac dysfunction induced by subarachnoid hemorrhage. | Role of galectin-3 in cardiac dysfunction induced by subarachnoid hemorrhage. Huang XX, Zhang QQ, Pang XX, Lin HB, He WY, Yuan D, Guo WJ, Zhang HF, Li FX. | 05/22/2023 |
Diffuse Myocardial Fibrosis on Cardiac Magnetic Resonance Imaging Is Related to Galectin-3 and Predicts Outcome in Heart Failure. | Diffuse Myocardial Fibrosis on Cardiac Magnetic Resonance Imaging Is Related to Galectin-3 and Predicts Outcome in Heart Failure. Screever EM, Gorter TM, Willems TP, Aboumsallem JP, Suthahar N, Mahmoud B, van Veldhuisen DJ, de Boer RA, Meijers WC., Free PMC Article | 04/1/2023 |
Chronic high-fat diet induces galectin-3 and TLR4 to activate NLRP3 inflammasome in NASH. | Chronic high-fat diet induces galectin-3 and TLR4 to activate NLRP3 inflammasome in NASH. Li H, Cao Z, Wang L, Li J, Cheng X, Tang Y, Xing M, Yao P. | 01/21/2023 |
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies. | Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies. Peiró T, Alonso-Carpio M, Ribera P, Almudéver P, Roger I, Montero P, Marín S, Milara J, Cortijo J., Free PMC Article | 01/7/2023 |
Hippocampal Galectin-3 knockdown alleviates lipopolysaccharide-induced neurotoxicity and cognitive deficits by inhibiting TLR4/NF-small ka, CyrillicB signaling in aged mice. | Hippocampal Galectin-3 knockdown alleviates lipopolysaccharide-induced neurotoxicity and cognitive deficits by inhibiting TLR4/NF-кB signaling in aged mice. Chen F, Wu X, Yang J, Yu X, Liu B, Yan Z. | 12/3/2022 |
Inhibition of Galectin-3 attenuates silica particles-induced silicosis via regulating the GSK-3beta/beta-catenin signal pathway-mediated epithelial-mesenchymal transition. | Inhibition of Galectin-3 attenuates silica particles-induced silicosis via regulating the GSK-3β/β-catenin signal pathway-mediated epithelial-mesenchymal transition. Wang T, Ou L, Li X, Zhang P, Miao Q, Niu R, Chen Y. | 12/3/2022 |
Mutation of the galectin-3 glycan-binding domain (Lgals3-R200S) enhances cortical bone expansion in male mice and trabecular bone mass in female mice. | Mutation of the galectin-3 glycan-binding domain (Lgals3-R200S) enhances cortical bone expansion in male mice and trabecular bone mass in female mice. Maupin KA, Diegel CR, Stevens PD, Dick D, VAI Vivarium and Transgenic Core, Williams BO., Free PMC Article | 10/15/2022 |
Genetic targeting or pharmacological inhibition of galectin-3 dampens microglia reactivity and delays retinal degeneration. | Genetic targeting or pharmacological inhibition of galectin-3 dampens microglia reactivity and delays retinal degeneration. Tabel M, Wolf A, Szczepan M, Xu H, Jägle H, Moehle C, Chen M, Langmann T., Free PMC Article | 10/8/2022 |
Galectin-3 protects auditory function in female mice. | Galectin-3 protects auditory function in female mice. Zhang C, Adler HJ, Manohar S, Salvi R, Sun W, Ye M, Hu BH. | 10/8/2022 |
Genetic Deletion of Galectin-3 Exacerbates Age-Related Myocardial Hypertrophy and Fibrosis in Mice. | Genetic Deletion of Galectin-3 Exacerbates Age-Related Myocardial Hypertrophy and Fibrosis in Mice. Fontana Estevez FS, Betazza MC, Miksztowicz V, Seropian IM, Silva MG, Penas F, Touceda V, Selser C, Villaverde A, Goren N, Cianciulli TF, Medina V, Morales C, Gironacci M, González GE. | 08/20/2022 |
Galectin-3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling. | Galectin-3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling. Cheng WL, Chen YC, Li SJ, Lee TI, Lee TW, Higa S, Chung CC, Kao YH, Chen SA, Chen YJ. | 07/30/2022 |
Galectin-3 ablation does not affect infarct size or inflammatory cytokines after experimental stroke in 24-month-old female mice. | Galectin-3 ablation does not affect infarct size or inflammatory cytokines after experimental stroke in 24-month-old female mice. Manouchehrian O, Andersson E, Eriksson-Hallberg B, Deierborg T., Free PMC Article | 07/16/2022 |