| The lncRNA MEG3/miRNA-21/P38MAPK axis inhibits coxsackievirus 3 replication in acute viral myocarditis. | The lncRNA MEG3/miRNA-21/P38MAPK axis inhibits coxsackievirus 3 replication in acute viral myocarditis.
He F, Liu Z, Feng M, Xiao Z, Yi X, Wu J, Liu Z, Wang G, Li L, Yao H., Free PMC Article | 12/28/2023 |
| LncRNA MEG3 aggravates adipocyte inflammation and insulin resistance by targeting IGF2BP2 to activate TLR4/NF-kappaB signaling pathway. | LncRNA MEG3 aggravates adipocyte inflammation and insulin resistance by targeting IGF2BP2 to activate TLR4/NF-κB signaling pathway.
Lu Y, Qie D, Yang F, Wu J. | 07/26/2023 |
| Inhibition of MEG3 ameliorates cardiomyocyte apoptosis and autophagy by regulating the expression of miRNA-129-5p in a mouse model of heart failure. | Inhibition of MEG3 ameliorates cardiomyocyte apoptosis and autophagy by regulating the expression of miRNA-129-5p in a mouse model of heart failure.
Mi S, Huang F, Jiao M, Qian Z, Han M, Miao Z, Zhan H., Free PMC Article | 06/23/2023 |
| MEG3 alleviates ankylosing spondylitis by suppressing osteogenic differentiation of mesenchymal stem cells through regulating microRNA-125a-5p-mediated TNFAIP3. | MEG3 alleviates ankylosing spondylitis by suppressing osteogenic differentiation of mesenchymal stem cells through regulating microRNA-125a-5p-mediated TNFAIP3.
Liu C, Liang T, Zhang Z, Chen J, Xue J, Zhan X, Ren L. | 04/20/2023 |
| Long non-coding RNA MEG3 alleviates postoperative cognitive dysfunction by suppressing inflammatory response and oxidative stress via has-miR-106a-5p/SIRT3. | Long non-coding RNA MEG3 alleviates postoperative cognitive dysfunction by suppressing inflammatory response and oxidative stress via has-miR-106a-5p/SIRT3.
Ye L, Cheng X, Shi Y, Liu Z, Xiong Y, Huang Y. | 04/10/2023 |
| LncRNA MEG3 inhibits renal fibrinoid necrosis of diabetic nephropathy via the MEG3/miR-21/ORAI1 axis. | LncRNA MEG3 inhibits renal fibrinoid necrosis of diabetic nephropathy via the MEG3/miR-21/ORAI1 axis.
Xu BW, Rao Y, Wang L, Chen SM, Zou SB. | 03/30/2023 |
| The long noncoding RNA Meg3 mediates TLR4-induced inflammation in experimental obstructive nephropathy. | The long noncoding RNA Meg3 mediates TLR4-induced inflammation in experimental obstructive nephropathy.
Yiu WH, Lok SWY, Xue R, Chen J, Lai KN, Lan HY, Tang SCW., Free PMC Article | 03/4/2023 |
| Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful extinction of fear. | Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful extinction of fear.
Royer M, Pai B, Menon R, Bludau A, Gryksa K, Perry RB, Ulitsky I, Meister G, Neumann ID., Free PMC Article | 12/10/2022 |
| Knockdown of lncRNA MEG3 protects against sepsis-induced acute lung injury in mice through miR-93-5p-dependent inhibition of NFkappaB signaling pathway. | Knockdown of lncRNA MEG3 protects against sepsis-induced acute lung injury in mice through miR-93-5p-dependent inhibition of NF‑κB signaling pathway.
Gao H, Zhang X, Tang F, Chen L, Tian Z, Xiao D, Li X. | 12/3/2022 |
| LncRNA MEG3 induces endothelial differentiation of mouse derived adipose-derived stem cells by targeting MiR-145-5p/KLF4. | LncRNA MEG3 induces endothelial differentiation of mouse derived adipose-derived stem cells by targeting MiR-145-5p/KLF4.
Zhang H, Liu G, Mao X, Yang L, Wang B, Yuan X. | 09/24/2022 |
| lncRNA MEG3 restrained the M1 polarization of microglia in acute spinal cord injury through the HuR/A20/NF-kappaB axis. | lncRNA MEG3 restrained the M1 polarization of microglia in acute spinal cord injury through the HuR/A20/NF-κB axis.
Zhou HJ, Wang LQ, Zhan RY, Zheng XJ, Zheng JS., Free PMC Article | 09/3/2022 |
| Glucose-6-phosphate dehydrogenase and MEG3 controls hypoxia-induced expression of serum response factor (SRF) and SRF-dependent genes in pulmonary smooth muscle cell. | Glucose-6-phosphate dehydrogenase and MEG3 controls hypoxia-induced expression of serum response factor (SRF) and SRF-dependent genes in pulmonary smooth muscle cell.
Kitagawa A, Jacob C, Gupte SA., Free PMC Article | 05/14/2022 |
| Long non-coding RNA MEG3 promotes tumor necrosis factor-alpha induced oxidative stress and apoptosis in interstitial cells of cajal via targeting the microRNA-21 /I-kappa-B-kinase beta axis. | Long non-coding RNA MEG3 promotes tumor necrosis factor-alpha induced oxidative stress and apoptosis in interstitial cells of cajal via targeting the microRNA-21 /I-kappa-B-kinase beta axis.
Li J, Bai J, Tuerdi N, Liu K., Free PMC Article | 05/7/2022 |
| LncRNA MEG3 regulates autophagy and pyroptosis via FOXO1 in pancreatic beta-cells. | LncRNA MEG3 regulates autophagy and pyroptosis via FOXO1 in pancreatic β-cells.
Li X, Bai C, Wang H, Wan T, Li Y. | 04/2/2022 |
| LncRNA MEG3 suppresses PI3K/AKT/mTOR signalling pathway to enhance autophagy and inhibit inflammation in TNF-alpha-treated keratinocytes and psoriatic mice. | LncRNA MEG3 suppresses PI3K/AKT/mTOR signalling pathway to enhance autophagy and inhibit inflammation in TNF-α-treated keratinocytes and psoriatic mice.
Tang ZL, Zhang K, Lv SC, Xu GW, Zhang JF, Jia HY. | 02/19/2022 |
| Mechanism of M2 macrophage-derived extracellular vesicles carrying lncRNA MEG3 in inflammatory responses in ulcerative colitis. | Mechanism of M2 macrophage-derived extracellular vesicles carrying lncRNA MEG3 in inflammatory responses in ulcerative colitis.
Wang YX, Lin C, Cui LJ, Deng TZ, Li QM, Chen FY, Miao XP., Free PMC Article | 02/19/2022 |
| LncRNA MEG3 alleviates PFOS induced placental cell growth inhibition through its derived miR-770 targeting PTX3. | LncRNA MEG3 alleviates PFOS induced placental cell growth inhibition through its derived miR-770 targeting PTX3.
Li J, Quan X, Lei S, Chen G, Hong J, Huang Z, Wang Q, Song W, Yang X. | 01/8/2022 |
| LncRNA MEG3 inhibits the proliferation of neural stem cells after ischemic stroke via the miR-493-5P/MIF axis. | LncRNA MEG3 inhibits the proliferation of neural stem cells after ischemic stroke via the miR-493-5P/MIF axis.
Zhao F, Xing Y, Jiang P, Hu L, Deng S. | 11/22/2021 |
| c-MYC-induced long noncoding RNA MEG3 aggravates kidney ischemia-reperfusion injury through activating mitophagy by upregulation of RTKN to trigger the Wnt/beta-catenin pathway. | c-MYC-induced long noncoding RNA MEG3 aggravates kidney ischemia-reperfusion injury through activating mitophagy by upregulation of RTKN to trigger the Wnt/β-catenin pathway.
Liu D, Liu Y, Zheng X, Liu N., Free PMC Article | 09/18/2021 |
| Long non-coding RNA MEG3 mediates the miR-149-3p/FOXP3 axis by reducing p53 ubiquitination to exert a suppressive effect on regulatory T cell differentiation and immune escape in esophageal cancer. | Long non-coding RNA MEG3 mediates the miR-149-3p/FOXP3 axis by reducing p53 ubiquitination to exert a suppressive effect on regulatory T cell differentiation and immune escape in esophageal cancer.
Xu QR, Tang J, Liao HY, Yu BT, He XY, Zheng YZ, Liu S., Free PMC Article | 09/11/2021 |
| LncRNA MEG3 regulates microglial polarization through KLF4 to affect cerebral ischemia-reperfusion injury. | LncRNA MEG3 regulates microglial polarization through KLF4 to affect cerebral ischemia-reperfusion injury.
Li T, Luo Y, Zhang P, Guo S, Sun H, Yan D, Liu X, Yang B. | 08/14/2021 |
| Hypermethylation and reduced expression of Gtl2, Rian and Mirg at the Dlk1-Dio3 imprinted locus as a marker for poor developmental potential of mouse embryonic stem cells. | Hypermethylation and reduced expression of Gtl2, Rian and Mirg at the Dlk1-Dio3 imprinted locus as a marker for poor developmental potential of mouse embryonic stem cells.
Schacker M, Cheng YH, Eckersley-Maslin M, Snaith RM, Colledge WH., Free PMC Article | 08/14/2021 |
| Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity. | Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity.
Cheng X, Shihabudeen Haider Ali MS, Moran M, Viana MP, Schlichte SL, Zimmerman MC, Khalimonchuk O, Feinberg MW, Sun X., Free PMC Article | 08/7/2021 |
| Identification of differentially expressed mRNA and the Hub mRNAs modulated by lncRNA Meg3 as a competing endogenous RNA in brown adipose tissue of mice on a high-fat diet. | Identification of differentially expressed mRNA and the Hub mRNAs modulated by lncRNA Meg3 as a competing endogenous RNA in brown adipose tissue of mice on a high-fat diet.
Zhang Y, Fu Y, Zheng Y, Wen Z, Wang C., Free PMC Article | 07/17/2021 |
| MEG3 Alleviated LPS-Induced Intestinal Injury in Sepsis by Modulating miR-129-5p and Surfactant Protein D. | MEG3 Alleviated LPS-Induced Intestinal Injury in Sepsis by Modulating miR-129-5p and Surfactant Protein D.
Du X, Tian D, Wei J, Yan C, Hu P, Wu X, Yang W., Free PMC Article | 07/10/2021 |