| Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations. | Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations.
Grieco A, Boneta S, Gavira JA, Pey AL, Basu S, Orlans J, Sanctis D, Medina M, Martin-Garcia JM., Free PMC Article | 03/20/2024 |
| Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy. | Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy.
Aleo SJ, Del Dotto V, Romagnoli M, Fiorini C, Capirossi G, Peron C, Maresca A, Caporali L, Capristo M, Tropeano CV, Zanna C, Ross-Cisneros FN, Sadun AA, Pignataro MG, Giordano C, Fasano C, Cavaliere A, Porcelli AM, Tioli G, Musiani F, Catania A, Lamperti C, Marzoli SB, De Negri A, Cascavilla ML, Battista M, Barboni P, Carbonelli M, Amore G, La Morgia C, Smirnov D, Vasilescu C, Farzeen A, Blickhaeuser B, Prokisch H, Priglinger C, Livonius B, Catarino CB, Klopstock T, Tiranti V, Carelli V, Ghelli AM., Free PMC Article | 02/24/2024 |
| Impact of NQO1 dysregulation in CNS disorders. | Impact of NQO1 dysregulation in CNS disorders.
Yuhan L, Khaleghi Ghadiri M, Gorji A., Free PMC Article | 01/17/2024 |
| Structural dynamics at the active site of the cancer-associated flavoenzyme NQO1 probed by chemical modification with PMSF. | Structural dynamics at the active site of the cancer-associated flavoenzyme NQO1 probed by chemical modification with PMSF.
Grieco A, Ruiz-Fresneda MA, Gómez-Mulas A, Pacheco-García JL, Quereda-Moraleda I, Pey AL, Martin-Garcia JM. | 11/22/2023 |
| MiR-766-3p and miR-671-5p attenuate aristolochic acid-induced hepatotoxicity by directly targeting the key bioactivating enzyme NQO1. | MiR-766-3p and miR-671-5p attenuate aristolochic acid-induced hepatotoxicity by directly targeting the key bioactivating enzyme NQO1.
Liu Y, Guan H, Feng M, Du C, Zhang Q, Shou Y, Qi G, Yu D, Jin Y. | 08/25/2023 |
| NQO1 drives glioblastoma cell aggressiveness through EMT induction via the PI3K/Akt/mTOR/Snail pathway. | NQO1 drives glioblastoma cell aggressiveness through EMT induction via the PI3K/Akt/mTOR/Snail pathway.
Zheng L, Yang S, Xu R, Yang Y, Quan J, Lin Z, Quan C., Free PMC Article | 08/22/2023 |
| Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis. | Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis.
Yu J, Zhong B, Zhao L, Hou Y, Ai N, Lu JJ, Ge W, Chen X. | 08/16/2023 |
| NQO1/CPT1A promotes the progression of pancreatic adenocarcinoma via fatty acid oxidation. | NQO1/CPT1A promotes the progression of pancreatic adenocarcinoma via fatty acid oxidation.
Xu R, Liu Y, Ma L, Sun Y, Liu H, Yang Y, Jin T, Yang D., Free PMC Article | 06/26/2023 |
| NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-kappaB and TGF-beta/Smad signaling pathways in diabetic nephropathy. | NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Qiu D, Song S, Chen N, Bian Y, Yuan C, Zhang W, Duan H, Shi Y. | 06/22/2023 |
| An antisense RNA promotes breast cancer metastasis via upregulation of NQO1. | An antisense RNA promotes breast cancer metastasis via upregulation of NQO1.
| 06/1/2023 |
| The Role of NQO1 in Ovarian Cancer. | The Role of NQO1 in Ovarian Cancer.
Tossetta G, Fantone S, Goteri G, Giannubilo SR, Ciavattini A, Marzioni D., Free PMC Article | 05/19/2023 |
| Elucidation of Increased Cervical Cancer Risk Due to Polymorphisms in XRCC1 (R399Q and R194W), ERCC5 (D1104H), and NQO1 (P187S). | Elucidation of Increased Cervical Cancer Risk Due to Polymorphisms in XRCC1 (R399Q and R194W), ERCC5 (D1104H), and NQO1 (P187S).
Das AP, Saini S, Tyagi S, Chaudhary N, Agarwal SM. | 05/10/2023 |
| NAD(P)H Quinone Oxidoreductase-1 Expression Promotes Self-Renewal and Therapeutic Resistance in Non-Small Cell Lung Cancer. | NAD(P)H Quinone Oxidoreductase-1 Expression Promotes Self-Renewal and Therapeutic Resistance in Non-Small Cell Lung Cancer.
Madajewski B, Boatman MA, Martinez I, Carter JH, Bey EA., Free PMC Article | 04/14/2023 |
| Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme. | Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme.
Pacheco-García JL, Anoz-Carbonell E, Loginov DS, Kavan D, Salido E, Man P, Medina M, Pey AL. | 04/7/2023 |
| Association of NAD (P) H Quinine Oxidoreductase 1 rs1800566 Polymorphism with Bladder and Prostate Cancers - a Systematic Review and Meta-Analysis. | Association of NAD (P) H Quinine Oxidoreductase 1 rs1800566 Polymorphism with Bladder and Prostate Cancers - a Systematic Review and Meta-Analysis.
Abedinzadeh M, Moghimi M, Dastgheib SA, Maleki H, Salehi E, Zare M, Jarahzadeh HM, Neamatzadeh H. | 03/11/2023 |
| NQO1 regulates cell cycle progression at the G2/M phase. | NQO1 regulates cell cycle progression at the G2/M phase.
Oh ET, Kim HG, Kim CH, Lee J, Kim C, Lee JS, Cho Y, Park HJ., Free PMC Article | 02/17/2023 |
| Spatial Analysis of NQO1 in Non-Small Cell Lung Cancer Shows Its Expression Is Independent of NRF1 and NRF2 in the Tumor Microenvironment. | Spatial Analysis of NQO1 in Non-Small Cell Lung Cancer Shows Its Expression Is Independent of NRF1 and NRF2 in the Tumor Microenvironment.
Kaghazchi B, Um IH, Elshani M, Read OJ, Harrison DJ., Free PMC Article | 11/19/2022 |
| An Axis between the Long Non-Coding RNA HOXA11-AS and NQOs Enhances Metastatic Ability in Oral Squamous Cell Carcinoma. | An Axis between the Long Non-Coding RNA HOXA11-AS and NQOs Enhances Metastatic Ability in Oral Squamous Cell Carcinoma.
Nakashima C, Fujiwara-Tani R, Mori S, Kishi S, Ohmori H, Fujii K, Mori T, Miyagawa Y, Yamamoto K, Kirita T, Luo Y, Kuniyasu H., Free PMC Article | 10/15/2022 |
| Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations. | Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations.
Pacheco-Garcia JL, Anoz-Carbonell E, Loginov DS, Vankova P, Salido E, Man P, Medina M, Palomino-Morales R, Pey AL. | 10/8/2022 |
| Polymorphisms in NQO1 and MPO genes and risk for bladder cancer in Tunisian population. | Polymorphisms in NQO1 and MPO genes and risk for bladder cancer in Tunisian population.
Hemissi I, Ayed H, Naimi Z, Meddeb K, Ayadi M, Zouari S, Zaghbib S, Talbi E, Chebil M, Ouerhani S., Free PMC Article | 06/18/2022 |
| Association of NQO1 levels and its genetic polymorphism with susceptibility to methamphetamine dependence. | Association of NQO1 levels and its genetic polymorphism with susceptibility to methamphetamine dependence.
Liu H, Zhang W, Deng XD, Ma Y, Liu Y., Free PMC Article | 03/26/2022 |
| Iron-mediated epigenetic activation of NRF2 targets. | Iron-mediated epigenetic activation of NRF2 targets.
Horniblow RD, Pathak P, Balacco DL, Acharjee A, Lles E, Gkoutos G, Beggs AD, Tselepis C. | 03/12/2022 |
| Effect of a sulforaphane supplement on muscle soreness and damage induced by eccentric exercise in young adults: A pilot study. | Effect of a sulforaphane supplement on muscle soreness and damage induced by eccentric exercise in young adults: A pilot study.
Komine S, Miura I, Miyashita N, Oh S, Tokinoya K, Shoda J, Ohmori H., Free PMC Article | 03/12/2022 |
| Intracellular Enzyme-Responsive Profluorophore and Prodrug Nanoparticles for Tumor-Specific Imaging and Precise Chemotherapy. | Intracellular Enzyme-Responsive Profluorophore and Prodrug Nanoparticles for Tumor-Specific Imaging and Precise Chemotherapy.
Pei Q, Lu S, Zhou J, Jiang B, Li C, Xie Z, Jing X. | 03/12/2022 |
| Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells. | Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells.
Burke R, Chu C, Zhou GD, Putluri V, Putluri N, Stading RE, Couroucli X, Lingappan K, Moorthy B., Free PMC Article | 02/19/2022 |