| Local monomer levels and established filaments potentiate non-muscle myosin 2 assembly. | Local monomer levels and established filaments potentiate non-muscle myosin 2 assembly.
Quintanilla MA, Patel H, Wu H, Sochacki KA, Chandrasekar S, Akamatsu M, Rotty JD, Korobova F, Bear JE, Taraska JW, Oakes PW, Beach JR., | 02/15/2024 |
| Myosin heavy chain 2 (MYH2) expression in hypertrophic chondrocytes of soft callus provokes endochondral bone formation in fracture. | Myosin heavy chain 2 (MYH2) expression in hypertrophic chondrocytes of soft callus provokes endochondral bone formation in fracture.
Jo S, Lee SH, Jeon C, Jo HR, You YJ, Lee JK, Sung IH, Kim TH, Lee CH. | 11/29/2023 |
| myosin IIa is essential for B cell development, proliferation, and antibody responses. | Myosin IIa Promotes Antibody Responses by Regulating B Cell Activation, Acquisition of Antigen, and Proliferation.
Hoogeboom R, Natkanski EM, Nowosad CR, Malinova D, Menon RP, Casal A, Tolar P., Free PMC Article | 12/7/2019 |
| nonmuscle myosin 2A replacement with myosin 2C1 permits gastrulation but not placenta vascular development in mice | Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice.
Zhang Y, Liu C, Adelstein RS, Ma X., Free PMC Article | 05/18/2019 |
| Inhibition of myosin IIA decreases annexin 1 nuclear translocation in oxygen-glucose deprivation. | Following OGD/R, annexin 1 nuclear translocation and subsequent induction of apoptosis in neurons are assisted by myosin IIA in a TRPM7 kinase-dependent manner.
Zhao Y, Wang J, Jiang H, Yu Z, Li X, Shi J. | 03/19/2016 |
| Myh2 expression was significantly higher in ESCs-mechanical group than that in the same group of MSCs. | Comparing the effect of uniaxial cyclic mechanical stimulation and chemical factors on myogenin and Myh2 expression in mouse embryonic and bone marrow derived mesenchymal stem cells.
Tannaz NA, Ali SM, Nooshin H, Nasser A, Reza M, Amir A, Maryam J. | 11/22/2014 |
| Activated T cell trans-endothelial migration relies on myosin-IIA contractility for squeezing the cell nucleus through endothelial cell barriers. | Activated T cell trans-endothelial migration relies on myosin-IIA contractility for squeezing the cell nucleus through endothelial cell barriers.
Jacobelli J, Estin Matthews M, Chen S, Krummel MF., Free PMC Article | 06/21/2014 |
| Myosin IIa has a role in upregulating early osteogenesis | Substrate curvature sensing through Myosin IIa upregulates early osteogenesis.
Ozdemir T, Xu LC, Siedlecki C, Brown JL. | 06/14/2014 |
| Myosin heavy chain 2A transcripts decreased significantly in skeletal muscle tissue from overnight parenterally fed patients but did not change significantly in orally refed mice | Myosin heavy chain 2A and α-actin expression in human and murine skeletal muscles at feeding; particularly amino acids.
Iresjö BM, Lundholm K., Free PMC Article | 04/6/2013 |
| Increase of CYP1A1-mRNA was due to nonmuscle myosin II inhibition. | Correlation of dysfunction of nonmuscle myosin IIA with increased induction of Cyp1a1 in Hepa-1 cells.
Ebina M, Shibazaki M, Kudo K, Kasai S, Kikuchi H. | 05/7/2011 |
| Calcium-mediated dephosphorylation of dynamin I at Ser-774 leads to the recruitment of the molecular motor myosin II to actively dilate the fusion pore to facilitate release of peptide transmitters. | Dynamin and myosin regulate differential exocytosis from mouse adrenal chromaffin cells.
Chan SA, Doreian B, Smith C., Free PMC Article | 04/16/2011 |
| GADD34 negatively regulates cell migration in wound healing via expression of myosin IIA. | GADD34 suppresses wound healing by upregulating expression of myosin IIA.
Tanaka C, Ito S, Nishio N, Kodera Y, Sakurai H, Suzuki H, Nakao A, Isobe K. | 12/4/2010 |
| Regulation of Myosin-IIA function in T cells is thus a key mechanism to regulate surface contact area and crawling velocity within different environments | Myosin-IIA and ICAM-1 regulate the interchange between two distinct modes of T cell migration.
Jacobelli J, Bennett FC, Pandurangi P, Tooley AJ, Krummel MF. | 01/21/2010 |
| replacement with oe Mysin 2A with myosin IIB rescues brain from hydrocephalus and manttains integrity of the spinal canal. | Replacement of nonmuscle myosin II-B with II-A rescues brain but not cardiac defects in mice.
Bao J, Ma X, Liu C, Adelstein RS. | 01/21/2010 |
| Both myosin IIA and myosin IIB are localized in nerve terminals. | Nonmuscle myosins IIA and IIB are present in adult motor nerve terminals.
Vega-Riveroll LJ, Wylie SR, Loughna PT, Parson SH, Chantler PD. | 01/21/2010 |
| conventional myosin motor, myosin IIA, drives neurite retraction. | Myosin IIA drives neurite retraction.
Wylie SR, Chantler PD., Free PMC Article | 01/21/2010 |
| In myotonic fast muscles, hyperexcitability leads to a drastic reduction of MyHC IIB which is compensated by IIA. | Specific isomyosin proportions in hyperexcitable and physiologically denervated mouse muscle.
Agbulut O, Noirez P, Butler-Browne G, Jockusch H. | 01/21/2010 |
| Data suggest that changes in intracellular calcium may play a role in shifts in myosin heavy chain IIa (MyHC IIa) expression during muscle activation. | Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter.
Allen DL, Leinwand LA. | 01/21/2010 |
| Data suggest that non-muscle myosin 2A is important for bipolar shape formation and adhesion owing to its preferential interaction with membrane-associated actin, and the role myosin 2B in retraction prevents over-elongation of myoblasts. | Non-muscle myosins 2A and 2B drive changes in cell morphology that occur as myoblasts align and fuse.
Swailes NT, Colegrave M, Knight PJ, Peckham M. | 01/21/2010 |
| mice ablated for NMHC II-A fail to develop a normal patterned embryo with a polarized visceral endoderm; defects in cell adhesion and tissue organization are explained by loss of E-cadherin and beta-catenin localization to cell adhesion sites | Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice.
Conti MA, Even-Ram S, Liu C, Yamada KM, Adelstein RS. | 01/21/2010 |
| IRF-2 is involved in up-regulation of nonmuscle myosin heavy chain II-A gene expression in cell differentiation | IRF-2 is involved in up-regulation of nonmuscle myosin heavy chain II-A gene expression during phorbol ester-induced promyelocytic HL-60 differentiation.
Chung MC, Kawamoto S. | 01/21/2010 |