| beta-Endorphin influences sedative and ataxic effects of alcohol. | β-Endorphin influences sedative and ataxic effects of alcohol.
Stea SG, Grisel JE. | 03/5/2024 |
| POMC-specific knockdown of MeCP2 leads to adverse phenotypes in mice chronically exposed to high fat diet. | POMC-specific knockdown of MeCP2 leads to adverse phenotypes in mice chronically exposed to high fat diet.
Frayre P, Ponce-Rubio K, Frayre J, Medrano J, Na ES., | 02/5/2024 |
| Solar ultraviolet B radiation promotes alpha-MSH secretion to attenuate the function of ILC2s via the pituitary-lung axis. | Solar ultraviolet B radiation promotes α-MSH secretion to attenuate the function of ILC2s via the pituitary-lung axis.
Huang Y, Zhu L, Cheng S, Dai R, Huang C, Song Y, Peng B, Li X, Wen J, Gong Y, Hu Y, Qian L, Zhu L, Zhang F, Yu L, Yi C, Gu W, Ling Z, Ma L, Tang W, Peng L, Shi G, Zhang Y, Sun B., Free PMC Article | 09/18/2023 |
| Proopiomelanocortin projections to the nucleus accumbens modulate acquisition and maintenance of operant palatable pellet administration in mice. | Proopiomelanocortin projections to the nucleus accumbens modulate acquisition and maintenance of operant palatable pellet administration in mice.
Eliason NL, Sharpe AL., | 04/20/2023 |
| Increased intrinsic and synaptic excitability of hypothalamic POMC neurons underlies chronic stress-induced behavioral deficits. | Increased intrinsic and synaptic excitability of hypothalamic POMC neurons underlies chronic stress-induced behavioral deficits.
Fang X, Chen Y, Wang J, Zhang Z, Bai Y, Denney K, Gan L, Guo M, Weintraub NL, Lei Y, Lu XY., Free PMC Article | 04/12/2023 |
| Developmental thyroid hormone action on pro-opiomelanocortin-expressing cells programs hypothalamic BMPR1A depletion and brown fat activation. | Developmental thyroid hormone action on pro-opiomelanocortin-expressing cells programs hypothalamic BMPR1A depletion and brown fat activation.
Wu Z, Martinez ME, DeMambro V, Francois M, Hernandez A., Free PMC Article | 03/7/2023 |
| Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice. | Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice.
Coppola I, Brouwers B, Walker L, Alar C, Meulemans S, White A, Ramos-Molina B, Creemers JWM., Free PMC Article | 01/14/2023 |
| Time and metabolic state-dependent effects of GLP-1R agonists on NPY/AgRP and POMC neuronal activity in vivo. | Time and metabolic state-dependent effects of GLP-1R agonists on NPY/AgRP and POMC neuronal activity in vivo.
Dong Y, Carty J, Goldstein N, He Z, Hwang E, Chau D, Wallace B, Kabahizi A, Lieu L, Peng Y, Gao Y, Hu L, Betley JN, Williams KW., Free PMC Article | 03/26/2022 |
| Functional heterogeneity of POMC neurons relies on mTORC1 signaling. | Functional heterogeneity of POMC neurons relies on mTORC1 signaling.
Saucisse N, Mazier W, Simon V, Binder E, Catania C, Bellocchio L, Romanov RA, Léon S, Matias I, Zizzari P, Quarta C, Cannich A, Meece K, Gonzales D, Clark S, Becker JM, Yeo GSH, Fioramonti X, Merkle FT, Wardlaw SL, Harkany T, Massa F, Marsicano G, Cota D. | 02/19/2022 |
| Involvement of histone deacetylase 1/2 in adrenocorticotropic hormone synthesis and proliferation of corticotroph tumor AtT-20 cells. | Involvement of histone deacetylase 1/2 in adrenocorticotropic hormone synthesis and proliferation of corticotroph tumor AtT-20 cells.
Hagiwara R, Kageyama K, Niioka K, Takayasu S, Tasso M, Daimon M. | 12/4/2021 |
| Tanycytic networks mediate energy balance by feeding lactate to glucose-insensitive POMC neurons. | Tanycytic networks mediate energy balance by feeding lactate to glucose-insensitive POMC neurons.
Lhomme T, Clasadonte J, Imbernon M, Fernandois D, Sauve F, Caron E, da Silva Lima N, Heras V, Martinez-Corral I, Mueller-Fielitz H, Rasika S, Schwaninger M, Nogueiras R, Prevot V., Free PMC Article | 11/22/2021 |
| beta-Endorphin and sex differentially modulate the response to EtOH in a site-specific manner. | β-Endorphin and sex differentially modulate the response to EtOH in a site-specific manner.
Rhinehart EM, Waldron M, Kelly-Quigley H, Zellers M, Turco A, Grisel JE. | 09/4/2021 |
| Hypothalamic Pomc expression restricted to GABAergic neurons suppresses Npy overexpression and restores food intake in obese mice. | Hypothalamic Pomc expression restricted to GABAergic neurons suppresses Npy overexpression and restores food intake in obese mice.
Trotta M, Bello EP, Alsina R, Tavella MB, Ferrán JL, Rubinstein M, Bumaschny VF., Free PMC Article | 07/10/2021 |
| Differential Effects of Fkbp4 and Fkbp5 on Regulation of the Proopiomelanocortin Gene in Murine AtT-20 Corticotroph Cells. | Differential Effects of Fkbp4 and Fkbp5 on Regulation of the Proopiomelanocortin Gene in Murine AtT-20 Corticotroph Cells.
Kageyama K, Iwasaki Y, Watanuki Y, Niioka K, Daimon M., Free PMC Article | 06/26/2021 |
| The activation of G protein-coupled receptor 30 increases pro-opiomelanocortin gene expression through cAMP/PKA/NR4A pathway in mouse pituitary corticotroph AtT-20 cells. | The activation of G protein-coupled receptor 30 increases pro-opiomelanocortin gene expression through cAMP/PKA/NR4A pathway in mouse pituitary corticotroph AtT-20 cells.
Takayasu S, Usutani M, Makita K, Daimon M. | 05/1/2021 |
| Hypothalamic POMC deficiency increases circulating adiponectin despite obesity. | Hypothalamic POMC deficiency increases circulating adiponectin despite obesity.
Yu H, Chhabra KH, Thompson Z, Jones GL, Kiran S, Shangguan G, Low MJ., Free PMC Article | 04/17/2021 |
| Metabolomics Reveals the Alteration of Metabolic Pathway by Alpha-Melanocyte-Stimulating Hormone in B16F10 Melanoma Cells. | Metabolomics Reveals the Alteration of Metabolic Pathway by Alpha-Melanocyte-Stimulating Hormone in B16F10 Melanoma Cells.
Seo SH, Jo JK, Kim EJ, Park SE, Shin SY, Park KM, Son HS., Free PMC Article | 03/6/2021 |
| The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight. | The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight.
Hael CE, Rojo D, Orquera DP, Low MJ, Rubinstein M., Free PMC Article | 02/27/2021 |
| Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy. | Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy.
Deshpande D, Agarwal N, Fleming T, Gaveriaux-Ruff C, Klose CSN, Tappe-Theodor A, Kuner R, Nawroth P., Free PMC Article | 02/2/2021 |
| Expression of a hypomorphic Pomc allele alters leptin dynamics during late pregnancy. | Expression of a hypomorphic Pomc allele alters leptin dynamics during late pregnancy.
Yu H, Thompson Z, Kiran S, Jones GL, Mundada L, Surbhi, Rubinstein M, Low MJ., Free PMC Article | 10/24/2020 |
| Both ACTH concentration and the HDL receptor Scarb1 play important independent roles in osteoblast differentiation. | The high-density lipoprotein receptor Scarb1 is required for normal bone differentiation in vivo and in vitro.
Tourkova IL, Dobrowolski SF, Secunda C, Zaidi M, Papadimitriou-Olivgeri I, Papachristou DJ, Blair HC. | 07/4/2020 |
| studies led to the discovery of NKX2.1, a transcription factor that participates in the early morphogenesis of the developing hypothalamus, as a key player in establishing the early identity of melanocortin neurons by activating Pomc expression | The Homeodomain Transcription Factor NKX2.1 Is Essential for the Early Specification of Melanocortin Neuron Identity and Activates Pomc Expression in the Developing Hypothalamus.
Orquera DP, Tavella MB, de Souza FSJ, Nasif S, Low MJ, Rubinstein M., Free PMC Article | 06/13/2020 |
| SOCS3 deficiency in POMC neurons influences body weight regulation in the setting of diet and differentially affects blood pressure and energy balance in a sex-specific manner | Role of SOCS3 in POMC neurons in metabolic and cardiovascular regulation.
Wang Z, do Carmo JM, da Silva AA, Bailey KC, Aberdein N, Moak SP, Hall JE., Free PMC Article | 01/4/2020 |
| Data show that pro-opiomelanocortin (Pomc) tm1/tm1 mouse obesity is sexually dimorphic and exacerbated by an high-fat (HF) diet. | Chronic High-Fat Diet Exacerbates Sexually Dimorphic Pomctm1/tm1 Mouse Obesity.
Hubbard K, Shome A, Sun B, Pontré B, McGregor A, Mountjoy KG., Free PMC Article | 12/21/2019 |
| Proton-induced CRHR1 signaling regulates ACTH production in response to an acidic microenvironment. | Proton Sensitivity of Corticotropin-Releasing Hormone Receptor 1 Signaling to Proopiomelanocortin in Male Mice.
Kameda H, Yamamoto M, Tone Y, Tone M, Melmed S., Free PMC Article | 12/7/2019 |