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    EGR1 early growth response 1 [ Homo sapiens (human) ]

    Gene ID: 1958, updated on 5-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Blocking EGR1/TGF-beta1 and CD44s/STAT3 Crosstalk Inhibits Peritoneal Metastasis of Gastric Cancer.

    Blocking EGR1/TGF-β1 and CD44s/STAT3 Crosstalk Inhibits Peritoneal Metastasis of Gastric Cancer.
    Jin Y, Wang C, Zhang B, Sun Y, Ji J, Cai Q, Jiang J, Zhang Z, Zhao L, Yu B, Zhang J., Free PMC Article

    03/5/2024
    EGR1 Regulates SHANK3 Transcription at Different Stages of Brain Development.

    EGR1 Regulates SHANK3 Transcription at Different Stages of Brain Development.
    Juan CX, Mao Y, Han X, Qian HY, Chu KK.

    02/29/2024
    EGR1 transcriptionally regulates SVEP1 to promote proliferation and migration in human coronary artery smooth muscle cells.

    EGR1 transcriptionally regulates SVEP1 to promote proliferation and migration in human coronary artery smooth muscle cells.
    Tian Q, Chen JH, Ding Y, Wang XY, Qiu JY, Cao Q, Zhuang LL, Jin R, Zhou GP.

    02/29/2024
    EGR1 suppresses HCC growth and aerobic glycolysis by transcriptionally downregulating PFKL.

    EGR1 suppresses HCC growth and aerobic glycolysis by transcriptionally downregulating PFKL.
    Pan M, Luo M, Liu L, Chen Y, Cheng Z, Wang K, Huang L, Tang N, Qiu J, Huang A, Xia J., Free PMC Article

    02/8/2024
    Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.

    Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.
    Yang R, Wang X, Liu H, Chen J, Tan C, Chen H, Wang X., Free PMC Article

    01/30/2024
    Early growth response 1 promoted the invasion of glioblastoma multiforme by elevating HMGB1.

    Early growth response 1 promoted the invasion of glioblastoma multiforme by elevating HMGB1.
    DU K, Wu X, Ji X, Liang N, Li Z.

    01/30/2024
    Tumor-mesothelium HOXA11-PDGF BB/TGF beta1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer.

    Tumor-mesothelium HOXA11-PDGF BB/TGF β1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer.
    Wang C, Ji J, Jin Y, Sun Y, Cai Q, Jiang J, Guo L, Zhou C, Zhang J., Free PMC Article

    01/27/2024
    EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8.

    EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8.
    Zhao Y, Sui L, Wu P, Li L, Liu L, Ma B, Wang W, Chi H, Wang Z-D, Wei Z, Hou Z, Zhang K, Niu J, Jin N, Li C, Zhao J, Wang G, Liu Q., Free PMC Article

    01/4/2024
    EGR1-mediated metabolic reprogramming to oxidative phosphorylation contributes to ibrutinib resistance in B-cell lymphoma.

    EGR1-mediated metabolic reprogramming to oxidative phosphorylation contributes to ibrutinib resistance in B-cell lymphoma.
    Liu Y, Kimpara S, Hoang NM, Daenthanasanmak A, Li Y, Lu L, Ngo VN, Bates PD, Song L, Gao X, Bebel S, Chen M, Chen R, Zhang X, Selberg PE, Kenkre VP, Waldmann TA, Capitini CM, Rui L.,

    12/1/2023
    EGR1 Promotes Ovarian Hyperstimulation Syndrome Through Upregulation of SOX9 Expression.

    EGR1 Promotes Ovarian Hyperstimulation Syndrome Through Upregulation of SOX9 Expression.
    Wang H, Chen W, Huang Y, Sun Y, Liu Y, Zhu Y, Lu Z., Free PMC Article

    11/7/2023
    Direct early growth response-1 knockdown decreases melanoma viability independent of mitogen-activated extracellular signal-related kinase inhibition.

    Direct early growth response-1 knockdown decreases melanoma viability independent of mitogen-activated extracellular signal-related kinase inhibition.
    Miley DR, Andrews-Pfannkoch CM, Pulido JS, Erickson SA, Vile RG, Fautsch MP, Marmorstein AD, Dalvin LA.,

    11/1/2023
    EGR1/LINC00839/SOX5 axis modulates migration, invasion and Gemcitabine resistance of bladder cancer cells.

    EGR1/LINC00839/SOX5 axis modulates migration, invasion and Gemcitabine resistance of bladder cancer cells.
    Wang Z, Wei B, Ma S., Free PMC Article

    10/28/2023
    EGR1 Regulation of Vasculogenic Mimicry in the MDA-MB-231 Triple-Negative Breast Cancer Cell Line through the Upregulation of KLF4 Expression.

    EGR1 Regulation of Vasculogenic Mimicry in the MDA-MB-231 Triple-Negative Breast Cancer Cell Line through the Upregulation of KLF4 Expression.
    Jung E, Lee YH, Ou S, Kim TY, Shin SY., Free PMC Article

    09/29/2023
    Tenogenic differentiation of human tendon-derived stem cells induced by long non-coding RNA LINCMD1 via miR-342-3p/EGR1 axis.

    Tenogenic differentiation of human tendon-derived stem cells induced by long non-coding RNA LINCMD1 via miR-342-3p/EGR1 axis.
    Qu F, Shen X, Wang K, Sun C, Li P.

    08/23/2023
    Role of early growth response 1 in inflammation-associated lung diseases.

    Role of early growth response 1 in inflammation-associated lung diseases.
    Zou K, Zeng Z., Free PMC Article

    08/4/2023
    N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21[cip1/waf1]/CDK2-Cyclin E1 axis-mediated cell cycle transition.

    N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition.
    Liu R, Miao J, Jia Y, Kong G, Hong F, Li F, Zhai M, Zhang R, Liu J, Xu X, Wang T, Liu H, Hu J, Yang Y, He A., Free PMC Article

    05/19/2023
    EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation.

    EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation.
    Cesana M, Tufano G, Panariello F, Zampelli N, Ambrosio S, De Cegli R, Mutarelli M, Vaccaro L, Ziller MJ, Cacchiarelli D, Medina DL, Ballabio A., Free PMC Article

    03/10/2023
    EGR1/NOX4 pathway regulates oxidative stress and further facilitates fibrosis progression in keloids responses to TGF-beta1.

    EGR1/NOX4 pathway regulates oxidative stress and further facilitates fibrosis progression in keloids responses to TGF-β1.
    Qin H, Zhang L, Li M, Liu Y, Sun S, Nie W, Bai B, Li G, Zhang G.

    02/27/2023
    GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1.

    GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1.
    Marks BA, Pipia IM, Mukai C, Horibata S, Rice EJ, Danko CG, Coonrod SA., Free PMC Article

    02/25/2023
    CircCOL5A1 inhibits proliferation, migration, invasion, and extracellular matrix production of keloid fibroblasts by regulating the miR-877-5p/EGR1 axis.

    CircCOL5A1 inhibits proliferation, migration, invasion, and extracellular matrix production of keloid fibroblasts by regulating the miR-877-5p/EGR1 axis.
    Jiao H, Ji G, Luo B, Chen C.

    01/11/2023
    Integrated analysis of mRNA-seq and miRNA-seq reveals the potential roles of Egr1, Rxra and Max in kidney stone disease.

    Integrated analysis of mRNA-seq and miRNA-seq reveals the potential roles of Egr1, Rxra and Max in kidney stone disease.
    Huang L, Shi Y, Hu J, Ding J, Guo Z, Yu B.

    12/31/2022
    FOCAD/miR-491-5p, downregulated by EGR1, function as tumor suppressor by inhibiting the proliferation and migration of gastric cancer cells.

    FOCAD/miR-491-5p, downregulated by EGR1, function as tumor suppressor by inhibiting the proliferation and migration of gastric cancer cells.
    Sun R, Liu Z, Lv Y, Yang Y, Yang Y, Xiang Y, Jiang Q, Zhao C, Lv M, Zhang J, Zhang J, Ding C, Zhou D.

    12/3/2022
    Next Generation Sequencing for Potential Regulated Genes and Micro-RNAs of Early Growth Response-1 in the Esophageal Squamous Cell Carcinoma.

    Next Generation Sequencing for Potential Regulated Genes and Micro-RNAs of Early Growth Response-1 in the Esophageal Squamous Cell Carcinoma.
    Tseng YC, Shu CW, Chang HM, Lin YH, Tseng YH, Hsu HS, Goan YG, Tseng CJ., Free PMC Article

    11/26/2022
    Transcription Factor EGR1 Regulates the Expression of the Clock Gene PER2 under IL-4 Stimulation in Human Keratinocytes.

    Transcription Factor EGR1 Regulates the Expression of the Clock Gene PER2 under IL-4 Stimulation in Human Keratinocytes.
    Yeo H, Ahn SS, Jung E, Lim Y, Lee YH, Shin SY.

    10/15/2022
    FRZB is Regulated by the Transcription Factor EGR1 and Inhibits the Growth and Invasion of Triple-Negative Breast Cancer Cells by Regulating the JAK/STAT3 Pathway.

    FRZB is Regulated by the Transcription Factor EGR1 and Inhibits the Growth and Invasion of Triple-Negative Breast Cancer Cells by Regulating the JAK/STAT3 Pathway.
    Liu H, Mei Y, Ma X, Zhang X, Nie W.

    10/8/2022
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