| MDSC-derived S100A8/9 contributes to lupus pathogenesis by promoting TLR7-mediated activation of macrophages and dendritic cells. | MDSC-derived S100A8/9 contributes to lupus pathogenesis by promoting TLR7-mediated activation of macrophages and dendritic cells.
Yang Y, Zhang X, Jing L, Xiao Y, Gao Y, Hu Y, Jia S, Zhou G, Xiong H, Dong G., Free PMC Article | 03/14/2024 |
| Deficiency of S100A8/A9 attenuates pulmonary microvascular leakage in septic mice. | Deficiency of S100A8/A9 attenuates pulmonary microvascular leakage in septic mice.
Yu J, Zhao B, Pi Q, Zhou G, Cheng Z, Qu C, Wang X, Kong L, Luo S, Du D, Guo Y., Free PMC Article | 03/14/2024 |
| Forkhead box A1 induces angiogenesis through activation of the S100A8/p38 MAPK axis in cutaneous wound healing. | Forkhead box A1 induces angiogenesis through activation of the S100A8/p38 MAPK axis in cutaneous wound healing.
Zhou Z, Zou M, Chen H, Zhu F, Wang T, Huang X. | 12/15/2023 |
| S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis. | S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis.
von Wulffen M, Luehrmann V, Robeck S, Russo A, Fischer-Riepe L, van den Bosch M, van Lent P, Loser K, Gabrilovich DI, Hermann S, Roth J, Vogl T. | 10/26/2023 |
| A positive feedback cycle between the alarmin S100A8/A9 and NLRP3 inflammasome-GSDMD signalling reinforces the innate immune response in Candida albicans keratitis. | A positive feedback cycle between the alarmin S100A8/A9 and NLRP3 inflammasome-GSDMD signalling reinforces the innate immune response in Candida albicans keratitis.
Fang X, Lian H, Liu S, Dong J, Hua X, Li W, Liao C, Yuan X. | 09/6/2023 |
| Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever. | Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever.
Jorch SK, McNally A, Berger P, Wolf J, Kaiser K, Chetrusca Covash A, Robeck S, Pastau I, Fehler O, Jauch-Speer SL, Hermann S, Schäfers M, Van Gorp H, Kanneganti A, Dehoorne J, Haerynck F, Penco F, Gattorno M, Chae JJ, Kubes P, Lamkanfi M, Wullaert A, Sperandio M, Vogl T, Roth J, Austermann J. | 07/24/2023 |
| S100a8/a9 contributes to sepsis-induced cardiomyopathy by activating ERK1/2-Drp1-mediated mitochondrial fission and respiratory dysfunction. | S100a8/a9 contributes to sepsis-induced cardiomyopathy by activating ERK1/2-Drp1-mediated mitochondrial fission and respiratory dysfunction.
Wu F, Zhang YT, Teng F, Li HH, Guo SB. | 02/28/2023 |
| Intracellular calprotectin (S100A8/A9) facilitates DNA damage responses and promotes apoptosis in head and neck squamous cell carcinoma. | Intracellular calprotectin (S100A8/A9) facilitates DNA damage responses and promotes apoptosis in head and neck squamous cell carcinoma.
Argyris PP, Saavedra F, Malz C, Stone IA, Wei Y, Boyle WS, Johnstone KF, Khammanivong A, Herzberg MC., Free PMC Article | 02/4/2023 |
| Role of S100A8/A9 in Platelet-Neutrophil Complex Formation during Acute Inflammation. | Role of S100A8/A9 in Platelet-Neutrophil Complex Formation during Acute Inflammation.
Revenstorff J, Ludwig N, Hilger A, Mersmann S, Lehmann M, Grenzheuser JC, Kardell M, Bone J, Kötting NM, Marx NC, Roth J, Vogl T, Rossaint J., Free PMC Article | 12/31/2022 |
| Integrated Analysis Reveals S100a8/a9 Regulates Autophagy and Apoptosis through the MAPK and PI3K-AKT Signaling Pathway in the Early Stage of Myocardial Infarction. | Integrated Analysis Reveals S100a8/a9 Regulates Autophagy and Apoptosis through the MAPK and PI3K-AKT Signaling Pathway in the Early Stage of Myocardial Infarction.
Yi W, Zhu R, Hou X, Wu F, Feng R., Free PMC Article | 07/2/2022 |
| C/EBPdelta-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9. | C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9.
Jauch-Speer SL, Herrera-Rivero M, Ludwig N, Véras De Carvalho BC, Martens L, Wolf J, Imam Chasan A, Witten A, Markus B, Schieffer B, Vogl T, Rossaint J, Stoll M, Roth J, Fehler O., Free PMC Article | 05/28/2022 |
| DOK3 maintains intestinal homeostasis by suppressing JAK2/STAT3 signaling and S100a8/9 production in neutrophils. | DOK3 maintains intestinal homeostasis by suppressing JAK2/STAT3 signaling and S100a8/9 production in neutrophils.
Loh JT, Lee KG, Lee AP, Teo JKH, Lim HL, Kim SS, Tan AH, Lam KP., Free PMC Article | 02/5/2022 |
| Serum Calprotectin Is a Potential Marker in Patients with Asthma. | Serum Calprotectin Is a Potential Marker in Patients with Asthma.
Lee YG, Hong J, Lee PH, Lee J, Park SW, Kim D, Jang AS., Free PMC Article | 11/6/2021 |
| S100A8/A9 is not essential for the development of inflammation and joint pathology in interleukin-1 receptor antagonist knockout mice. | S100A8/A9 is not essential for the development of inflammation and joint pathology in interleukin-1 receptor antagonist knockout mice.
Di Ceglie I, van Lent PLEM, Geven EJW, Koenders MI, Blom AB, Vogl T, Roth J, van den Bosch MHJ., Free PMC Article | 09/11/2021 |
| S100A8 promotes epithelial-mesenchymal transition and metastasis under TGF-beta/USF2 axis in colorectal cancer. | S100A8 promotes epithelial-mesenchymal transition and metastasis under TGF-β/USF2 axis in colorectal cancer.
Li S, Zhang J, Qian S, Wu X, Sun L, Ling T, Jin Y, Li W, Sun L, Lai M, Xu F., Free PMC Article | 09/4/2021 |
| The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis. | The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis.
Blom AB, van den Bosch MH, Blaney Davidson EN, Roth J, Vogl T, van de Loo FA, Koenders M, van der Kraan PM, Geven EJ, van Lent PL., Free PMC Article | 08/14/2021 |
| Deletion of S100a8 and S100a9 Enhances Skin Hyperplasia and Promotes the Th17 Response in Imiquimod-Induced Psoriasis. | Deletion of S100a8 and S100a9 Enhances Skin Hyperplasia and Promotes the Th17 Response in Imiquimod-Induced Psoriasis.
Defrêne J, Berrazouane S, Esparza N, Pagé N, Côté MF, Gobeil S, Aoudjit F, Tessier PA. | 08/7/2021 |
| Immune Resolution Dilemma: Host Antimicrobial Factor S100A8/A9 Modulates Inflammatory Collateral Tissue Damage During Disseminated Fungal Peritonitis. | Immune Resolution Dilemma: Host Antimicrobial Factor S100A8/A9 Modulates Inflammatory Collateral Tissue Damage During Disseminated Fungal Peritonitis.
Shankar M, Uwamahoro N, Backman E, Holmberg S, Niemiec MJ, Roth J, Vogl T, Urban CF., Free PMC Article | 07/3/2021 |
| S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants. | S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants.
Willers M, Ulas T, Völlger L, Vogl T, Heinemann AS, Pirr S, Pagel J, Fehlhaber B, Halle O, Schöning J, Schreek S, Löber U, Essex M, Hombach P, Graspeuntner S, Basic M, Bleich A, Cloppenborg-Schmidt K, Künzel S, Jonigk D, Rupp J, Hansen G, Förster R, Baines JF, Härtel C, Schultze JL, Forslund SK, Roth J, Viemann D. | 04/17/2021 |
| Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis. | Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis.
Ha JS, Choi HR, Kim IS, Kim EA, Cho SW, Yang SJ., Free PMC Article | 04/17/2021 |
| S100a8 silencing attenuates inflammation, oxidative stress and apoptosis in BV2 cells induced by oxygenglucose deprivation and reoxygenation by upregulating GAB1 expression. | S100a8 silencing attenuates inflammation, oxidative stress and apoptosis in BV2 cells induced by oxygen‑glucose deprivation and reoxygenation by upregulating GAB1 expression.
Hu W, Lin C., Free PMC Article | 04/17/2021 |
| Proinflammatory S100A8 Induces PD-L1 Expression in Macrophages, Mediating Tumor Immune Escape. | Proinflammatory S100A8 Induces PD-L1 Expression in Macrophages, Mediating Tumor Immune Escape.
Li Z, Wang J, Zhang X, Liu P, Zhang X, Wang J, Zheng X, Wei L, Peng Q, Liu C, Yan Q, Shen S, Li X, Ma J. | 02/20/2021 |
| S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis. | S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis.
Scott NR, Swanson RV, Al-Hammadi N, Domingo-Gonzalez R, Rangel-Moreno J, Kriel BA, Bucsan AN, Das S, Ahmed M, Mehra S, Treerat P, Cruz-Lagunas A, Jimenez-Alvarez L, Muñoz-Torrico M, Bobadilla-Lozoya K, Vogl T, Walzl G, du Plessis N, Kaushal D, Scriba TJ, Zúñiga J, Khader SA., Free PMC Article | 02/6/2021 |
| Target-Specific Imaging of Cathepsin and S100A8/A9 Reflects Specific Features of Malignancy and Enables Estimation of Tumor Malignancy. | Target-Specific Imaging of Cathepsin and S100A8/A9 Reflects Specific Features of Malignancy and Enables Estimation of Tumor Malignancy.
Helfen A, Große Hokamp N, Geyer C, Heindel W, Bremer C, Vogl T, Höltke C, Masthoff M, Barczyk-Kahlert K, Roth J, Wildgruber M, Eisenblaetter M. | 01/23/2021 |
| NETosis Is Required for S100A8/A9-Induced Granulopoiesis After Myocardial Infarction. | NETosis Is Required for S100A8/A9-Induced Granulopoiesis After Myocardial Infarction.
Nagareddy PR, Sreejit G, Abo-Aly M, Jaggers RM, Chelvarajan L, Johnson J, Pernes G, Athmanathan B, Abdel-Latif A, Murphy AJ., Free PMC Article | 12/19/2020 |