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    Ccl5 C-C motif chemokine ligand 5 [ Mus musculus (house mouse) ]

    Gene ID: 20304, updated on 11-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Role of the CCL5 and Its Receptor, CCR5, in the Genesis of Aldosterone-Induced Hypertension, Vascular Dysfunction, and End-Organ Damage.

    Role of the CCL5 and Its Receptor, CCR5, in the Genesis of Aldosterone-Induced Hypertension, Vascular Dysfunction, and End-Organ Damage.
    Costa RM, Cerqueira DM, Bruder-Nascimento A, Alves JV, Awata WMC, Singh S, Kufner A, Prado DS, Johny E, Cifuentes-Pagano E, Hawse WF, Dutta P, Pagano PJ, Ho J, Bruder-Nascimento T.,

    03/25/2024
    CCL5 mediated astrocyte-T cell interaction disrupts blood-brain barrier in mice after hemorrhagic stroke.

    CCL5 mediated astrocyte-T cell interaction disrupts blood-brain barrier in mice after hemorrhagic stroke.
    Zhou S, Liu C, Wang J, Ye J, Lian Q, Gan L, Deng S, Xu T, Guo Y, Li W, Zhang Z, Yang GY, Tang Y.,

    02/22/2024
    CircMAPK1 promoted CD8 + T cell infiltration in LUAD by improving the IGF2BP1 dependent CCL5 upregulation.

    CircMAPK1 promoted CD8 + T cell infiltration in LUAD by improving the IGF2BP1 dependent CCL5 upregulation.
    Zhao F, Zhu G, He J, Xu X, Zhu W, Jiang W, He G.

    01/29/2024
    C-C Motif Chemokine Ligand 5 (CCL5) Promotes Irradiation-Evoked Osteoclastogenesis.

    C-C Motif Chemokine Ligand 5 (CCL5) Promotes Irradiation-Evoked Osteoclastogenesis.
    Wang J, Zhao F, Xu L, Wang J, Zhai J, Ren L, Zhu G., Free PMC Article

    11/29/2023
    Identification of C-C motif chemokine ligand 5 as a heat-dependent myokine.

    Identification of C-C motif chemokine ligand 5 as a heat-dependent myokine.
    Murata K, Ishiuchi-Sato Y, Nedachi T.

    06/30/2023
    Single cell transcriptomics of bone marrow derived macrophages reveals Ccl5 as a biomarker of direct IFNAR-independent responses to DNA sensing.

    Single cell transcriptomics of bone marrow derived macrophages reveals Ccl5 as a biomarker of direct IFNAR-independent responses to DNA sensing.
    McCarty E, Yu J, Ninh VK, Calcagno DM, Lee J, King KR., Free PMC Article

    06/13/2023
    HSV-1 infection-induced herpetic neuralgia involves a CCL5/CCR5-mediated inflammation mechanism.

    HSV-1 infection-induced herpetic neuralgia involves a CCL5/CCR5-mediated inflammation mechanism.
    Wu S, Yang S, Li R, Ba X, Jiang C, Xiong D, Xiao L, Sun W.

    05/24/2023
    Upregulation of CCL5/RANTES Gene Expression in the Diaphragm of Mice with Cholestatic Liver Disease.

    Upregulation of CCL5/RANTES Gene Expression in the Diaphragm of Mice with Cholestatic Liver Disease.
    Morales V, González A, Cabello-Verrugio C.

    04/26/2023
    CCL5/CCR5-mediated peripheral inflammation exacerbates blood-brain barrier disruption after intracerebral hemorrhage in mice.

    CCL5/CCR5-mediated peripheral inflammation exacerbates blood‒brain barrier disruption after intracerebral hemorrhage in mice.
    Lin J, Xu Y, Guo P, Chen YJ, Zhou J, Xia M, Tan B, Liu X, Feng H, Chen Y., Free PMC Article

    03/19/2023
    Convergent transcriptomic and genomic evidence supporting a dysregulation of CXCL16 and CCL5 in Alzheimer's disease.

    Convergent transcriptomic and genomic evidence supporting a dysregulation of CXCL16 and CCL5 in Alzheimer's disease.
    Li X, Zhang DF, Bi R, Tan LW, Chen X, Xu M, Yao YG., Free PMC Article

    02/11/2023
    Metabolic effects of CCL5 deficiency in lean and obese mice.

    Metabolic effects of CCL5 deficiency in lean and obese mice.
    Zhou H, Liao X, Zeng Q, Zhang H, Song J, Hu W, Sun X, Ding Y, Wang D, Xiao Y, Deng T., Free PMC Article

    02/4/2023
    C-C motif chemokine ligand 5 confines liver regeneration by down-regulating reparative macrophage-derived hepatocyte growth factor in a forkhead box O 3a-dependent manner.

    C-C motif chemokine ligand 5 confines liver regeneration by down-regulating reparative macrophage-derived hepatocyte growth factor in a forkhead box O 3a-dependent manner.
    Huang M, Jiao J, Cai H, Zhang Y, Xia Y, Lin J, Shang Z, Qian Y, Wang F, Wu H, Kong X, Gu J., Free PMC Article

    11/26/2022
    RGMa regulates CCL5 expression via the BMP receptor in experimental autoimmune encephalomyelitis mice and endothelial cells.

    RGMa regulates CCL5 expression via the BMP receptor in experimental autoimmune encephalomyelitis mice and endothelial cells.
    Tang S, Su B, Tao T, Yan W, Zhang R, Qin X, Feng J., Free PMC Article

    04/2/2022
    Role of myeloid-derived chemokine CCL5/RANTES at an early stage of atherosclerosis.

    Role of myeloid-derived chemokine CCL5/RANTES at an early stage of atherosclerosis.
    Jongstra-Bilen J, Tai K, Althagafi MG, Siu A, Scipione CA, Karim S, Polenz CK, Ikeda J, Hyduk SJ, Cybulsky MI.

    01/15/2022
    A translational study: Involvement of miR-21-5p in development and maintenance of neuropathic pain via immune-related targets CCL5 and YWHAE.

    A translational study: Involvement of miR-21-5p in development and maintenance of neuropathic pain via immune-related targets CCL5 and YWHAE.
    Karl-Schöller F, Kunz M, Kreß L, Held M, Egenolf N, Wiesner A, Dandekar T, Sommer C, Üçeyler N.

    01/1/2022
    Anti-tumor immunity in mismatch repair-deficient colorectal cancers requires type I IFN-driven CCL5 and CXCL10.

    Anti-tumor immunity in mismatch repair-deficient colorectal cancers requires type I IFN-driven CCL5 and CXCL10.
    Mowat C, Mosley SR, Namdar A, Schiller D, Baker K., Free PMC Article

    11/27/2021
    CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury.

    CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury.
    Ho MH, Yen CH, Hsieh TH, Kao TJ, Chiu JY, Chiang YH, Hoffer BJ, Chang WC, Chou SY., Free PMC Article

    10/30/2021
    C-C chemokine hepatocellular carcinoma motif ligand 5-deficiency promotes hepatocellular carcinoma progression by affecting B cell recruitment.

    C-C chemokine hepatocellular carcinoma motif ligand 5-deficiency promotes hepatocellular carcinoma progression by affecting B cell recruitment.
    Li X, Han QC, Yu C, Luo YC, Wang F, Sun XH, Gao YQ, Tan WF, Xia Q.

    10/2/2021
    Gene electrotransfer of proinflammatory chemokines CCL5 and CCL17 as a novel approach of modifying cytokine expression profile in the tumor microenvironment.

    Gene electrotransfer of proinflammatory chemokines CCL5 and CCL17 as a novel approach of modifying cytokine expression profile in the tumor microenvironment.
    Bozic T, Sersa G, Kranjc Brezar S, Cemazar M, Markelc B.

    09/18/2021
    CCL5 deficiency promotes liver repair by improving inflammation resolution and liver regeneration through M2 macrophage polarization.

    CCL5 deficiency promotes liver repair by improving inflammation resolution and liver regeneration through M2 macrophage polarization.
    Li M, Sun X, Zhao J, Xia L, Li J, Xu M, Wang B, Guo H, Yu C, Gao Y, Wu H, Kong X, Xia Q., Free PMC Article

    07/31/2021
    CCL5 mediates CD40-driven CD4+ T cell tumor infiltration and immunity.

    CCL5 mediates CD40-driven CD4+ T cell tumor infiltration and immunity.
    Huffman AP, Lin JH, Kim SI, Byrne KT, Vonderheide RH., Free PMC Article

    05/22/2021
    Chrysin Inhibits NF-kappaB-Dependent CCL5 Transcription by Targeting IkappaB Kinase in the Atopic Dermatitis-Like Inflammatory Microenvironment.

    Chrysin Inhibits NF-κB-Dependent CCL5 Transcription by Targeting IκB Kinase in the Atopic Dermatitis-Like Inflammatory Microenvironment.
    Yeo H, Lee YH, Koh D, Lim Y, Shin SY., Free PMC Article

    02/27/2021
    ALPK1 regulates streptozotocin-induced nephropathy through CCL2 and CCL5 expressions.

    ALPK1 regulates streptozotocin-induced nephropathy through CCL2 and CCL5 expressions.
    Lee CP, Nithiyanantham S, Hsu HT, Yeh KT, Kuo TM, Ko YC., Free PMC Article

    09/12/2020
    ACKR2 dampens CCL5 levels and the consequent recruitment of CCR5(+) T helper 1 (Th1).

    ACKR2 contributes to pulmonary dysfunction by shaping CCL5:CCR5-dependent recruitment of lymphocytes during influenza A infection in mice.
    Tavares LP, Garcia CC, Gonçalves APF, Kraemer LR, Melo EM, Oliveira FMS, Freitas CS, Lopes GAO, Reis DC, Cassali GD, Machado AM, Mantovani A, Locati M, Teixeira MM, Russo RC.

    07/18/2020
    RUNX3-mediated CCL5 repression is critical for modulating anti-tumor immunity.

    Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity.
    Seo W, Shimizu K, Kojo S, Okeke A, Kohwi-Shigematsu T, Fujii SI, Taniuchi I., Free PMC Article

    07/18/2020
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