| Histological and transcriptomic analysis of Fance-deficient PGCs reveal the possible mechanisms of their depletion. | Histological and transcriptomic analysis of Fance-deficient PGCs reveal the possible mechanisms of their depletion.
Suye S, Yin H, Zhou Z, Zheng C, Ren Z, Shi L, Fu C. | 06/15/2023 |
| Fanconi Anemia Complementation Group E, a DNA Repair-Related Gene, Is a Potential Marker of Poor Prognosis in Hepatocellular Carcinoma. | Fanconi Anemia Complementation Group E, a DNA Repair-Related Gene, Is a Potential Marker of Poor Prognosis in Hepatocellular Carcinoma.
Takahashi J, Masuda T, Kitagawa A, Tobo T, Nakano Y, Abe T, Ando Y, Kosai K, Kobayashi Y, Matsumoto Y, Yoshizumi T, Mori M, Mimori K. | 02/5/2022 |
| Comprehensive analysis of macrophage-related multigene signature in the tumor microenvironment of head and neck squamous cancer. | Comprehensive analysis of macrophage-related multigene signature in the tumor microenvironment of head and neck squamous cancer.
Lin B, Li H, Zhang T, Ye X, Yang H, Shen Y., Free PMC Article | 07/24/2021 |
| A novel alternative splicing event of the FANCE gene has been characterized. FANCEDelta4 cannot support the activation of the FANC-BRCA pathway and DNA repair. | Analysis of a FANCE Splice Isoform in Regard to DNA Repair.
Bouffard F, Plourde K, Bélanger S, Ouellette G, Labrie Y, Durocher F. | 12/26/2015 |
| a phenylalanine located at the highly conserved extreme C terminus, referred to as Phe-522, is a critical residue for mediating the monoubiquitination of the FANCD2-FANCI complex. | The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.
Polito D, Cukras S, Wang X, Spence P, Moreau L, D'Andrea AD, Kee Y., Free PMC Article | 06/28/2014 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | See all PubMed (2) articlesComprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.
Monsees GM, Kraft P, Chanock SJ, Hunter DJ, Han J. Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population.
Loizidou MA, Cariolou MA, Neuhausen SL, Newbold RF, Bashiardes E, Marcou Y, Michael T, Daniel M, Kakouri E, Papadopoulos P, Malas S, Hadjisavvas A, Kyriacou K. | 06/30/2010 |
| Observational study and meta-analysis of gene-disease association. (HuGE Navigator) | Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.
Palmieri RT, Wilson MA, Iversen ES, Clyde MA, Calingaert B, Moorman PG, Poole C, Anderson AR, Anderson S, Anton-Culver H, Beesley J, Hogdall E, Brewster W, Carney ME, Chen X, Chenevix-Trench G, Chang-Claude J, Cunningham JM, Dicioccio RA, Doherty JA, Easton DF, Edlund CK, Gayther SA, Gentry-Maharaj A, Goode EL, Goodman MT, Kjaer SK, Hogdall CK, Hopkins MP, Jenison EL, Blaakaer J, Lurie G, McGuire V, Menon U, Moysich KB, Ness RB, Pearce CL, Pharoah PD, Pike MC, Ramus SJ, Rossing MA, Song H, Terada KY, Vandenberg D, Vierkant RA, Wang-Gohrke S, Webb PM, Whittemore AS, Wu AH, Ziogas A, Berchuck A, Schildkraut JM, Ovarian Cancer Association Consortium, Australian Cancer Study (Ovarian Cancer Group), Australian Ovarian Cancer Study Group., Free PMC Article | 01/11/2009 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (4) articlesInvestigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.
Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A. Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.
McWilliams RR, Bamlet WR, de Andrade M, Rider DN, Couch FJ, Cunningham JM, Matsumoto ME, Rabe KG, Hammer TJ, Petersen GM. The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features.
Barroso E, Pita G, Arias JI, Menendez P, Zamora P, Blanco M, Benitez J, Ribas G. Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.
Vega A, Salas A, Milne RL, Carracedo B, Ribas G, Ruibal A, de León AC, González-Hernández A, Benítez J, Carracedo A. | 11/5/2008 |
| Chk1-mediated phosphorylation of FANCE is required for a function independent of FANCD2 monoubiquitination. | Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway.
Wang X, Kennedy RD, Ray K, Stuckert P, Ellenberger T, D'Andrea AD., Free PMC Article | 01/21/2010 |
| This Fanconi anemia protein promotes the nuclear accumulation of FANCC. | The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC.
Taniguchi T, D'Andrea AD. | 01/21/2010 |
| Disease-associated mutations disrupt the FANCE-FANCD2 interaction, providing structural insight into the molecular mechanisms of Fanconi Anaemia pathogenesis. | Insights into Fanconi Anaemia from the structure of human FANCE.
Nookala RK, Hussain S, Pellegrini L., Free PMC Article | 01/21/2010 |
| FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage. | FANCE: the link between Fanconi anaemia complex assembly and activity.
Pace P, Johnson M, Tan WM, Mosedale G, Sng C, Hoatlin M, de Winter J, Joenje H, Gergely F, Patel KJ., Free PMC Article | 01/21/2010 |
| FANCC, FANCE, and FANCD2 form a ternary complex in the Fanconi anemia DNA damage response pathway | FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway.
Gordon SM, Alon N, Buchwald M. | 01/21/2010 |
| nuclear accumulation of FANCE does not rely solely on its nuclear localization signal motifs, but also on FANCC | The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC.
Léveillé F, Ferrer M, Medhurst AL, Laghmani el H, Rooimans MA, Bier P, Steltenpool J, Titus TA, Postlethwait JH, Hoatlin ME, Joenje H, de Winter JP. | 01/21/2010 |