Role of gut-derived bacterial lipopolysaccharide and peripheral TLR4 in immobilization stress-induced itch aggravation in a mouse model of atopic dermatitis. | Role of gut-derived bacterial lipopolysaccharide and peripheral TLR4 in immobilization stress-induced itch aggravation in a mouse model of atopic dermatitis. Cho DE, Hong JP, Kim Y, Sim JY, Kim HS, Kim SR, Lee B, Cho HS, Cho IH, Shin S, Yeom M, Kwon SK, Lee IS, Park H, Kim K, Hahm DH., Free PMC Article | 03/20/2024 |
PE12 interaction with TLR4 promotes intracellular survival of Mycobacterium tuberculosis by suppressing inflammatory response. | PE12 interaction with TLR4 promotes intracellular survival of Mycobacterium tuberculosis by suppressing inflammatory response. Zhang J, Cui Y, Zang X, Feng T, Chen F, Wang H, Dang G, Liu S. | 03/15/2024 |
Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis. | Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis. Wang S, Han Y, Liu R, Hou M, Neumann D, Zhang J, Wang F, Li Y, Zhao X, Schianchi F, Dai C, Liu L, Nabben M, Glatz JFC, Wu X, Lu X, Li X, Luiken JJFP., Free PMC Article | 03/5/2024 |
LPS-TLR4 pathway exaggerates alcoholic hepatitis via provoking NETs formation. | LPS-TLR4 pathway exaggerates alcoholic hepatitis via provoking NETs formation. Liu Y, Chen S, Yu S, Wang J, Zhang X, Lv H, Aboubacar H, Gao N, Ran X, Sun Y, Cao G. | 02/21/2024 |
DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection. | DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection. Xu J, Liu LY, Zhi FJ, Song YJ, Zhang ZH, Li B, Zheng FY, Gao PC, Zhang SZ, Zhang YY, Zhang Y, Qiu Y, Jiang B, Li YQ, Peng C, Chu YF., Free PMC Article | 02/20/2024 |
MiR129-5p-loaded exosomes suppress seizure-associated neurodegeneration in status epilepticus model mice by inhibiting HMGB1/TLR4-mediated neuroinflammation. | MiR129-5p-loaded exosomes suppress seizure-associated neurodegeneration in status epilepticus model mice by inhibiting HMGB1/TLR4-mediated neuroinflammation. Liu T, Liu H, Xue S, Xiao L, Xu J, Tong S, Wei X., Free PMC Article | 02/15/2024 |
Tlr4 Deletion Modulates Cytokine and Extracellular Matrix Expression in Chronic Spinal Cord Injury, Leading to Improved Secondary Damage and Functional Recovery. | Tlr4 Deletion Modulates Cytokine and Extracellular Matrix Expression in Chronic Spinal Cord Injury, Leading to Improved Secondary Damage and Functional Recovery. Ryan F, Francos-Quijorna I, Hernández-Mir G, Aquino C, Schlapbach R, Bradbury EJ, David S., Free PMC Article | 02/14/2024 |
LPS/TLR4 Pathway Regulates IgA1 Secretion to Induce IgA Nephropathy. | LPS/TLR4 Pathway Regulates IgA1 Secretion to Induce IgA Nephropathy. He H, Shen M, Tang Y, Sun W, Xu X. | 02/5/2024 |
Hepatocytes-derived Prdx1 regulates macrophage phenotypes via TLR4 activation in acute liver injury. | Hepatocytes-derived Prdx1 regulates macrophage phenotypes via TLR4 activation in acute liver injury. Zhang Y, Zhang X, Zhang M, Zhang F, Chen T, Zha J, Shen Q, Wang D, Hou C. | 01/29/2024 |
Neutrophil extracellular traps aggravate intestinal epithelial necroptosis in ischaemia-reperfusion by regulating TLR4/RIPK3/FUNDC1-required mitophagy. | Neutrophil extracellular traps aggravate intestinal epithelial necroptosis in ischaemia-reperfusion by regulating TLR4/RIPK3/FUNDC1-required mitophagy. Chu C, Wang X, Chen F, Yang C, Shi L, Xu W, Wang K, Liu B, Wang C, Sun D, Li J, Ding W., Free PMC Article | 01/9/2024 |
The role of TLR4/MyD88/NF-kappaB in the protective effect of ulinastatin on the intestinal mucosal barrier in mice with sepsis. | The role of TLR4/MyD88/NF-κB in the protective effect of ulinastatin on the intestinal mucosal barrier in mice with sepsis. Wenying S, Jing H, Ying L, Hui D., Free PMC Article | 12/26/2023 |
The role of the Toll like receptor 4 signaling in sex-specific persistency of depression-like behavior in response to chronic stress. | The role of the Toll like receptor 4 signaling in sex-specific persistency of depression-like behavior in response to chronic stress. Yang EJ, Frolinger T, Iqbal U, Estill M, Shen L, Trageser KJ, Pasinetti GM. | 12/26/2023 |
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis. | Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis. Wu Y, Du S, Bimler LH, Mauk KE, Lortal L, Kichik N, Griffiths JS, Osicka R, Song L, Polsky K, Kasper L, Sebo P, Weatherhead J, Knight JM, Kheradmand F, Zheng H, Richardson JP, Hube B, Naglik JR, Corry DB., Free PMC Article | 12/5/2023 |
MCPIP1 alleviates depressive-like behaviors in mice by inhibiting the TLR4/TRAF6/NF-kappaB pathway to suppress neuroinflammation. | MCPIP1 alleviates depressive‑like behaviors in mice by inhibiting the TLR4/TRAF6/NF‑κB pathway to suppress neuroinflammation. An Q, Xia J, Pu F, Shi S., Free PMC Article | 11/30/2023 |
PSMC5 regulates microglial polarization and activation in LPS-induced cognitive deficits and motor impairments by interacting with TLR4. | PSMC5 regulates microglial polarization and activation in LPS-induced cognitive deficits and motor impairments by interacting with TLR4. Bi W, Bao K, Zhou X, Deng Y, Li X, Zhang J, Lan X, Zhao J, Lu D, Xu Y, Cen Y, Cao R, Xu M, Zhong W, Zhu L., Free PMC Article | 11/28/2023 |
Involvement of TLR4 in Acute Hepatitis Associated with Airway Infection of Murine gamma-Herpesvirus 68. | Involvement of TLR4 in Acute Hepatitis Associated with Airway Infection of Murine γ-Herpesvirus 68. Kanai K, Kageyama S, Yoshie O. | 11/13/2023 |
Activation of Toll-like receptor 4 by thyroid hormone triggers abnormal B-cell activation. | Activation of Toll-like receptor 4 by thyroid hormone triggers abnormal B-cell activation. Wang J, Li GQ, Liu S, Miao JJ, Sun Q, Gu WS, Mao XM., Free PMC Article | 10/10/2023 |
LncRNA ANRIL Promotes Autophagy Activation Through miR-16-5p/TLR4 Axis in Allergic Rhinitis. | LncRNA ANRIL Promotes Autophagy Activation Through miR-16-5p/TLR4 Axis in Allergic Rhinitis. Wang MQ, Zhu XH, Liu K, Tian XY, Liu YH. | 10/10/2023 |
Toll-like receptor 4 promotes the inflammatory response in septic acute kidney injury by promoting p38 mitogen-activated protein kinase phosphorylation. | Toll-like receptor 4 promotes the inflammatory response in septic acute kidney injury by promoting p38 mitogen-activated protein kinase phosphorylation. Yue L, Liu X, Wu C, Lai J, Wang J, Zhong H, Chen F., Free PMC Article | 10/6/2023 |
Escherichia coli adhesion portion FimH polarizes M2 macrophages to M1 macrophages in tumor microenvironment via toll-like receptor 4. | Escherichia coli adhesion portion FimH polarizes M2 macrophages to M1 macrophages in tumor microenvironment via toll-like receptor 4. Zhang W, Xu L, Zhang X, Xu J, Jin JO., Free PMC Article | 09/28/2023 |
Fecal microbiota transplantation alleviates experimental colitis through the Toll-like receptor 4 signaling pathway. | Fecal microbiota transplantation alleviates experimental colitis through the Toll-like receptor 4 signaling pathway. Wen X, Xie R, Wang HG, Zhang MN, He L, Zhang MH, Yang XZ., Free PMC Article | 09/27/2023 |
miR-15a-5p up-regulates TLR4 and induces the formation of hypertrophic scars and keloids. | miR-15a-5p up-regulates TLR4 and induces the formation of hypertrophic scars and keloids. Pang J, Zhu L, Lv Y, Xu L, Li N, Guo P, Feng Q. | 09/25/2023 |
Disruption of Histamine-H1R signaling exacerbates cardiac microthrombosis after periodontal disease via TLR4/NFkappaB-p65 pathway. | Disruption of Histamine-H(1)R signaling exacerbates cardiac microthrombosis after periodontal disease via TLR4/NFκB-p65 pathway. Yang X, Shi Z, Wang X, Yang Y, Sun D, Zhu B, Song F, Zhu X, Ding S, Zou Y, Xiao C, Yang X. | 09/23/2023 |
Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus. | Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus. Hsieh YT, Chen YC, Chou YC, Kuo PY, Yen YT, Tsai HW, Wang CR., Free PMC Article | 09/18/2023 |
The Protective Role of TLR4 in Intestinal Epithelial Cells through the Regulation of the Gut Microbiota in DSS-Induced Colitis in Mice. | The Protective Role of TLR4 in Intestinal Epithelial Cells through the Regulation of the Gut Microbiota in DSS-Induced Colitis in Mice. Shi YJ, Huang C, Gong PQ, Liu C, Hu ZQ, Wang H. | 09/13/2023 |