| Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda. | Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda.
Nyangiri OA, Mulindwa J, Namulondo J, Kitibwa A, Nassuuna J, Elliott A, Kimuda MP, Boobo A, Nerima B, Adriko M, Dunton NJ, Madhan GK, Kristiansen M, Casacuberta-Partal M, Noyes H, Matovu E, TrypanoGEN+ Research group of the H3Africa consortium., Free PMC Article | 12/21/2023 |
| l-ficolin-MASP arm of the complement system in schizophrenia. | l-ficolin-MASP arm of the complement system in schizophrenia.
Mayilyan KR, Krarup A, Soghoyan AF, Jensenius JC, Sim RB. | 03/8/2023 |
| Selected SNPs of FCN2 Associated with Chronic Tonsillitis in the Polish Adult Population. | Selected SNPs of FCN2 Associated with Chronic Tonsillitis in the Polish Adult Population.
Gaździcka J, Gołąbek K, Hudy D, Miśkiewicz-Orczyk K, Zięba N, Tynior W, Asman M, Misiołek M, Strzelczyk JK., Free PMC Article | 03/2/2023 |
| Association of the FCN2 Gene Promoter Region Polymorphisms with Very Low Birthweight in Preterm Neonates. | Association of the FCN2 Gene Promoter Region Polymorphisms with Very Low Birthweight in Preterm Neonates.
Szala-Poździej A, Świerzko AS, Gajek G, Kufelnicka-Babout M, Chojnacka K, Kobiela P, Jarych D, Sobczuk K, Mazela J, Domżalska-Popadiuk I, Kalinka J, Sekine H, Matsushita M, Cedzyński M., Free PMC Article | 01/7/2023 |
| Ficolin-2 Lectin Complement Pathway Mediates Capsule-Specific Innate Immunity Against Invasive Pneumococcal Disease. | Ficolin-2 Lectin Complement Pathway Mediates Capsule-Specific Innate Immunity Against Invasive Pneumococcal Disease.
Nahm MH, Yu J, Calix JJ, Ganaie F., Free PMC Article | 04/30/2022 |
| Ficolin-2 Plasma Level Assesses Liver Fibrosis in Non-Alcoholic Fatty Liver Disease. | Ficolin-2 Plasma Level Assesses Liver Fibrosis in Non-Alcoholic Fatty Liver Disease.
Giraudi PJ, Salvoza N, Bonazza D, Saitta C, Lombardo D, Casagranda B, de Manzini N, Pollicino T, Raimondo G, Tiribelli C, Palmisano S, Rosso N., Free PMC Article | 04/16/2022 |
| Ficolin-2 serum levels predict the occurrence of acute coronary syndrome in patients with severe carotid artery stenosis. | Ficolin-2 serum levels predict the occurrence of acute coronary syndrome in patients with severe carotid artery stenosis.
Carbone F, Valente A, Perego C, Bertolotto M, Pane B, Spinella G, Palombo D, De Simoni MG, Montecucco F, Fumagalli S. | 01/15/2022 |
| Novel FCN2 Variants and Haplotypes are Associated with Rheumatic Heart Disease. | Novel FCN2 Variants and Haplotypes are Associated with Rheumatic Heart Disease.
Badarukhiya JA, Tupperwar N, Nizamuddin S, Mulpur AK, Thangaraj K. | 10/23/2021 |
| Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults. | Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults.
Sokołowska A, Świerzko AS, Gajek G, Gołos A, Michalski M, Nowicki M, Szala-Poździej A, Wolska-Washer A, Brzezińska O, Wierzbowska A, Jamroziak K, Kowalski ML, Thiel S, Matsushita M, Jensenius JC, Cedzyński M., Free PMC Article | 01/16/2021 |
| Circulating Ficolin-2 and Ficolin-3 Form Heterocomplexes. | Circulating Ficolin-2 and Ficolin-3 Form Heterocomplexes.
Jarlhelt I, Pilely K, Clausen JB, Skjoedt MO, Bayarri-Olmos R, Garred P. | 10/24/2020 |
| Association of FCN2 polymorphisms and Ficolin-2 levels with dengue fever in Vietnamese patients. | Association of FCN2 polymorphisms and Ficolin-2 levels with dengue fever in Vietnamese patients.
Giang NT, Tong HV, Nghia TH, Hung HV, Anh DT, Nam LV, Mao CV, Giang NT, Thanh LD, Son HA, Velavan TP, Do Q, Toan NL. | 08/22/2020 |
| Insufficient serum L-ficolin is associated with disease progression in pulmonary Mycobacterium avium complex disease. | Insufficient serum L-ficolin is associated with disease presence and extent of pulmonary Mycobacterium avium complex disease.
Kobayashi T, Kuronuma K, Saito A, Ikeda K, Ariki S, Saitou A, Otsuka M, Chiba H, Takahashi S, Takahashi M, Takahashi H., Free PMC Article | 04/4/2020 |
| The FCN2 promoter polymorphisms may contribute to susceptibility to Pediatric-onset systemic lupus erythematosus (pSLE) in Egyptian children and adolescents. Moreover, the FCN2 GG genotype at position -986 and AA genotype at position -4 were associated with low serum ficolin-2 levels and may constitute risk factors for lupus nephritis in pSLE. | Association of ficolin-2 gene polymorphisms and susceptibility to systemic lupus erythematosus in Egyptian children and adolescents: a multicenter study.
Elkoumi MA, Emam AA, Allah MAN, Sherif AH, Abdelaal NM, Mosabah A, Zakaria MT, Soliman MM, Salah A, Sedky YM, Mashali MH, Elashkar SSA, Hafez SFM, Hashem MIA, Elshreif AM, Youssef M, Fahmy DS, Sallam MM, Nawara AM, Elgohary EA, Ahmed AA, Fahim MS, Fawzi MM, Abdou AM, Morsi SS, Abo-Alella DA, Malek MM, Anany HG, Sobeih AA, Elbasyouni HAA, El-Deeb FM. | 01/11/2020 |
| The skewed age distribution of the three serotypes suggests that older adults have reduced ficolin-2-mediated immunity and are more susceptible to these serotypes. | Ficolin-2 binds to serotype 35B pneumococcus as it does to serotypes 11A and 31, and these serotypes cause more infections in older adults than in children.
Geno KA, Spencer BL, Bae S, Nahm MH., Free PMC Article | 05/25/2019 |
| This illustrates that ficolin-2 expression in hepatocytes contributes to innate resistance to hepatotropic virus infection, but some viruses might utilize ficolin-2 to facilitate entry. | Expression of human ficolin-2 in hepatocytes confers resistance to infection by diverse hepatotropic viruses.
Jalal PJ, Urbanowicz RA, Horncastle E, Pathak M, Goddard C, Saeed A, Mason CP, Ball JK, Irving WL, McClure CP, King BJ, Tarr AW. | 04/27/2019 |
| this study shows that ficolin-2 gene rs7851696 polymorphism is associated with delayed graft function and acute rejection in klidney allograft recipients | Ficolin-2 Gene rs7851696 Polymorphism is Associated with Delayed Graft Function and Acute Rejection in Kidney Allograft Recipients.
Dabrowska-Zamojcin E, Czerewaty M, Malinowski D, Tarnowski M, Słuczanowska-Głabowska S, Domanski L, Safranow K, Pawlik A., Free PMC Article | 08/25/2018 |
| the minority (C) allele at -64 of the FCN2 gene was less frequent among juvenile idiopathic arthritis patients than among control subjects | Lectin pathway factors in patients suffering from juvenile idiopathic arthritis.
Kasperkiewicz K, Eppa Ł, Świerzko AS, Bartłomiejczyk MA, Żuber ZM, Siniewicz-Luzeńczyk K, Mężyk E, Matsushita M, Bąk-Romaniszyn L, Zeman K, Skurnik M, Cedzyński M. | 06/23/2018 |
| This is the first study evaluating the FCN2 gene polymorphisms in patients with rheumatic fever and rheumatic carditis finding a protective effect of -986 GG and -4 GG genotypes in the development of rheumatic fever and the -4 AG genotype for the development of carditis. | MBL2 and FCN2 gene polymorphisms in a cohort of Italian children with rheumatic fever: A case-control study.
Marzetti V, Di Battista C, Ferrante R, Carlucci L, Balsamo M, Stuppia L, Lapergola G, Antonucci I, Chiarelli F, Breda L. | 06/2/2018 |
| this study did not find any association of FCN2 (encoding ficolin-2 protein) promoter polymorphisms at positions -986, -602, and -4 with dental caries in Polish children. | The Lack of Association between FCN2 Gene Promoter Region Polymorphisms and Dental Caries in Polish Children.
Olszowski T, Milona M, Janiszewska-Olszowska J, Safranow K, Skonieczna-Żydecka K, Walczak A, Sikora M, Chlubek D, Madlani A, Adler G. | 01/20/2018 |
| Serum ficolin-2 concentrations in multiple tumor patients are significantly lower than those in healthy donors. | Ficolin-2 triggers antitumor effect by activating macrophages and CD8(+) T cells.
Ding Q, Shen Y, Li D, Yang J, Yu J, Yin Z, Zhang XL. | 11/26/2017 |
| this study shows that Ficolin-2 plasma level is associated with short- and long-term mortality in patients with necrotizing soft tissue infection in Denmark | The Lectin Complement Pathway in Patients with Necrotizing Soft Tissue Infection.
Hansen MB, Rasmussen LS, Pilely K, Hellemann D, Hein E, Madsen MB, Hyldegaard O, Garred P., Free PMC Article | 10/7/2017 |
| The results suggest that the Arctic populations of East Siberia are characterised by specificity of genetic make-up responsible for the activity of L-ficolin. | The prevalence of the variants of the L-ficolin gene (FCN2) in the arctic populations of East Siberia.
Smolnikova MV, Freidin MB, Tereshchenko SY. | 09/9/2017 |
| study provides evidence for an important role for the lectin pathway in the inflammatory response induced by cholesterol crystals (CC) and emphasize the role of ficolin-2 and MBL in the CC-mediated inflammation occurring during atherosclerotic plaque development | Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis.
Pilely K, Rosbjerg A, Genster N, Gal P, Pál G, Halvorsen B, Holm S, Aukrust P, Bakke SS, Sporsheim B, Nervik I, Niyonzima N, Bartels ED, Stahl GL, Mollnes TE, Espevik T, Garred P. | 08/5/2017 |
| FCN2 inhibits epithelial-mesenchymal transition-induced metastasis of hepatocellular carcinoma via TGF-beta1/Smad signaling. | FCN2 inhibits epithelial-mesenchymal transition-induced metastasis of hepatocellular carcinoma via TGF-β/Smad signaling.
Yang G, Liang Y, Zheng T, Song R, Wang J, Shi H, Sun B, Xie C, Li Y, Han J, Pan S, Lan Y, Liu X, Zhu M, Wang Y, Liu L. | 07/22/2017 |
| this study shows that FCN2 polymorphisms is not a major risk factor for community-acquired pneumonia in general, but that the +6424G>T SNP in the FCN2 gene predisposes to Coxiella burnetii pneumonia | Mannose-binding lectin and l-ficolin polymorphisms in patients with community-acquired pneumonia caused by intracellular pathogens.
van Kempen G, Meijvis S, Endeman H, Vlaminckx B, Meek B, de Jong B, Rijkers G, Bos WJ., Free PMC Article | 06/3/2017 |