| A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family. | A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family.
Xie X, Du J, Geng S, Yi B, Li Q, Zuo J., Free PMC Article | 03/13/2024 |
| A novel missense mutation (FGG c.1168G > T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype. | A novel missense mutation (FGG c.1168G > T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype.
Xu N, Zheng L, Dai Z, Zhu J, Xie P, Yang S, Chen F., Free PMC Article | 01/30/2024 |
| [Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene]. | [Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene].
Shao X, Ma J, Wang Z, Sun M, Huang Z, Jiang Z, Liu X, Li S, Liu Y. | 12/18/2023 |
| Two Novel Heterozygous Mutations (p.gammaPhe230Val and p.AalphaAsn839Thr) Cause Hereditary Hypodysfibrinogenemia in Two Chinese Independent Families. | Two Novel Heterozygous Mutations (p.γPhe230Val and p.AαAsn839Thr) Cause Hereditary Hypodysfibrinogenemia in Two Chinese Independent Families.
Ge S, Luo Y, Dong R, Guo X, Wang M, Chen Y. | 06/13/2023 |
| Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population. | Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population.
Zhang Z, Li H, Weng H, Zhou G, Chen H, Yang G, Zhang P, Zhang X, Ji Y, Ying K, Liu B, Xu Q, Tang Y, Zhu G, Liu Z, Xia S, Yang X, Dong L, Zhu L, Zeng M, Yuan Y, Yang Y, Zhang N, Xu X, Pang W, Zhang M, Zhang Y, Zhen K, Wang D, Lei J, Wu S, Shu S, Zhang Y, Zhang S, Gao Q, Huang Q, Deng C, Fu X, Chen G, Duan W, Wan J, Xie W, Zhang P, Wang S, Yang P, Zuo X, Zhai Z, Wang C, China pUlmonary Thromboembolism REgistry Study (CURES) investigators., Free PMC Article | 05/4/2023 |
| Plasma proteomics analysis of adolescent idiopathic scoliosis patients revealed by Quadrupole-Orbitrap mass spectrometry. | Plasma proteomics analysis of adolescent idiopathic scoliosis patients revealed by Quadrupole-Orbitrap mass spectrometry.
Wang Q, Wang C, Liu J, Sun J, Wang C, Zhang X. | 02/5/2022 |
| Sensitivity analysis of a reduced model of thrombosis under flow: Roles of Factor IX, Factor XI, and gamma'-Fibrin. | Sensitivity analysis of a reduced model of thrombosis under flow: Roles of Factor IX, Factor XI, and γ'-Fibrin.
Chen J, Diamond SL., Free PMC Article | 01/8/2022 |
| Changes and significance of plasma fibrinogen gamma-chain concentration in preeclampsia patients. | Changes and significance of plasma fibrinogen gamma-chain concentration in preeclampsia patients.
Zhu Y, Tan Y, Liang X, OuYang L, Wang Y, Tan L, Shen C, Xu W, Hu Z, Zhou H., Free PMC Article | 11/13/2021 |
| High fibrinogen gamma' levels in patient plasma increase clot formation at arterial and venous shear. | High fibrinogen γ' levels in patient plasma increase clot formation at arterial and venous shear.
Macrae FL, Swieringa F, Heemskerk JWM, Ariëns RAS., Free PMC Article | 11/6/2021 |
| Novel variant fibrinogen gammap.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment. | Novel variant fibrinogen γp.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment.
Yoda M, Kaido T, Kamijo T, Taira C, Higuchi Y, Arai S, Okumura N. | 09/4/2021 |
| Identification and characterization of novel mutations in Chinese patients with congenital fibrinogen disorders. | Identification and characterization of novel mutations in Chinese patients with congenital fibrinogen disorders.
Zhou P, Yu M, Peng Y, Ma P, Wan L. | 07/3/2021 |
| Recombinant gammaY278H Fibrinogen Showed Normal Secretion from CHO Cells, but a Corresponding Heterozygous Patient Showed Hypofibrinogenemia. | Recombinant γY278H Fibrinogen Showed Normal Secretion from CHO Cells, but a Corresponding Heterozygous Patient Showed Hypofibrinogenemia.
Kamijo T, Kaido T, Yoda M, Arai S, Yamauchi K, Okumura N., Free PMC Article | 07/3/2021 |
| Fibrinogen gamma gene rs2066865 and risk of cancer-related venous thromboembolism. | Fibrinogen gamma gene rs2066865 and risk of cancer-related venous thromboembolism.
Paulsen B, Skille H, Smith EN, Hveem K, Gabrielsen ME, Brækkan SK, Rosendaal FR, Frazer KA, Gran OV, Hansen JB., Free PMC Article | 05/8/2021 |
| Thermal shift assay to probe melting of thrombin, fibrinogen, fibrin monomer, and fibrin: Gly-Pro-Arg-Pro induces a fibrin monomer-like state in fibrinogen. | Thermal shift assay to probe melting of thrombin, fibrinogen, fibrin monomer, and fibrin: Gly-Pro-Arg-Pro induces a fibrin monomer-like state in fibrinogen.
Crossen J, Diamond SL., Free PMC Article | 04/24/2021 |
| Genetic Variants in the FGB and FGG Genes Mapping in the Beta and Gamma Nodules of the Fibrinogen Molecule in Congenital Quantitative Fibrinogen Disorders Associated with a Thrombotic Phenotype. | Genetic Variants in the FGB and FGG Genes Mapping in the Beta and Gamma Nodules of the Fibrinogen Molecule in Congenital Quantitative Fibrinogen Disorders Associated with a Thrombotic Phenotype.
Simurda T, Brunclikova M, Asselta R, Caccia S, Zolkova J, Kolkova Z, Loderer D, Skornova I, Hudecek J, Lasabova Z, Stasko J, Kubisz P., Free PMC Article | 04/17/2021 |
| A Mendelian randomization of gamma' and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke. | A Mendelian randomization of γ' and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke.
Maners J, Gill D, Pankratz N, Laffan MA, Wolberg AS, de Maat MPM, Ligthart S, Tang W, Ward-Caviness CK, Fornage M, Debette S, Dichgans M, McKnight B, Boerwinkle E, CHARGE Inflammation Working Group, INVENT Consortium, MEGASTROKE consortium of the International Stroke Genetics Consortium (ISGC), Smith NL, Morrison AC, Dehghan A, de Vries PS., Free PMC Article | 04/13/2021 |
| Mutations Causing Mild or No Structural Damage in Interfaces of Multimerization of the Fibrinogen gamma-Module More Likely Confer Negative Dominant Behaviors. | Mutations Causing Mild or No Structural Damage in Interfaces of Multimerization of the Fibrinogen γ-Module More Likely Confer Negative Dominant Behaviors.
Bellacchio E., Free PMC Article | 03/6/2021 |
| [A case of inherited afibrinogenemia caused by an IVS7-12A>G splice mutation of FGG gene]. | [A case of inherited afibrinogenemia caused by an IVS7-12A>G splice mutation of FGG gene].
Wang X, Yang X, Wang J, Shu K, Li F, Yang W, Ruan J, Wang S, Jiang M. | 01/9/2021 |
| Quantitative Serum Proteomic Study Reveals that Fibrinogen-Related Proteins May Participate in the Pathophysiological Process of Simple Febrile Convulsion. | Quantitative Serum Proteomic Study Reveals that Fibrinogen-Related Proteins May Participate in the Pathophysiological Process of Simple Febrile Convulsion.
Li C, Zhao X, Zhao Y, Liu X, Zhang J, Li S, Zhou Z, Yin Y, Ma W, Wang H. | 12/5/2020 |
| Preoperative Serum Fibrinogen is Associated With Acute Kidney Injury after Cardiac Valve Replacement Surgery. | Preoperative Serum Fibrinogen is Associated With Acute Kidney Injury after Cardiac Valve Replacement Surgery.
Yang JJ, Lei WH, Hu P, Wu BB, Chen JX, Ni YM, Lai EY, Han F, Chen JH, Yang Y., Free PMC Article | 11/28/2020 |
| This study examined the polymerization abilities of the recombinant fibrinogen gamma variants, gammaD318Y and gammaK321E. No polymerization was observed for gammaD318Y fibrinogen, similar to gammaDeltaN319D320. gammaK321E fibrinogen showed slightly reduced polymerization. | γD318Y fibrinogen shows no fibrin polymerization due to defective "A-a" and "B-b" interactions, whereas that of γK321E fibrinogen is nearly normal.
Kamijo T, Mukai S, Taira C, Higuchi Y, Okumura N. | 05/2/2020 |
| Three new mutations affecting splicing were detected in FGG gene: fibrinogen Poznan II, fibrinogen Zakopane and fibrinogen Belchatow. Like in other populations, hotspot mutations linked to dysfibrinogenemia were observed in most patients. | Genetic and clinical characterization of congenital fibrinogen disorders in Polish patients: Identification of three novel fibrinogen gamma chain mutations.
Wypasek E, Klukowska A, Zdziarska J, Zawilska K, Treliński J, Iwaniec T, Mital A, Pietrys D, Sydor W, Neerman-Arbez M, Undas A. | 05/2/2020 |
| We analyzed the association of a single nucleotide polymorphism (SNP) in rs2066865 in the fibrinogen gamma chain (FGG) gene, alteration in plasma fibrinogen concentration, and presence of microvascular flap thrombosis. | Polymorphism rs2066865 in the Fibrinogen Gamma Chain (FGG) Gene Increases Plasma Fibrinogen Concentration and Is Associated with an Increased Microvascular Thrombosis Rate.
Drizlionoka K, Zariņš J, Ozoliņa A, Ņikitina-Zaķe L, Mamaja B., Free PMC Article | 03/28/2020 |
| Fibrinogen Columbus II: A novel c.1075G>T mutation in the FGG gene causing hypodysfibrinogenemia and thrombosis in an adolescent male. | Fibrinogen Columbus II: A novel c.1075G>T mutation in the FGG gene causing hypodysfibrinogenemia and thrombosis in an adolescent male.
Kumar R, Dawson J, Varga E, Canini JT, Monda KL, Dunn AL. | 01/25/2020 |
| Fibrinogen FGA, FGB and FGG genes were sequenced in 17 patients by next-generation sequencing. Variants leading to fibrinogen deficiency were found in all patients. Eight novel variants were described. | Clinical and molecular characterization by next generation sequencing of Spanish patients affected by congenital deficiencies of fibrinogen.
Moret A, Zúñiga Á, Ibáñez M, Cid AR, Haya S, Ferrando F, Blanquer A, Cervera J, Bonanad S. | 01/11/2020 |