HMGB1/SET/HAT1 complex-mediated SASH1 repression drives glycolysis and metastasis in lung adenocarcinoma. | HMGB1/SET/HAT1 complex-mediated SASH1 repression drives glycolysis and metastasis in lung adenocarcinoma. Kou F, Wu L, Zheng Y, Yi Y, Ji Z, Huang Z, Guo S, Yang L. | 11/14/2023 |
SASH1 contributes to glial cell migration in the early development of the central nervous system. | SASH1 contributes to glial cell migration in the early development of the central nervous system. Zhou Z, Wang P, Wang Q, Dong Z, Chen X, Zhuo R, Wu R, Liu Y, Yang L, Liu M. | 11/10/2023 |
Two novel mutations in SASH1 identified in a familial and a sporadic generalized lentiginosis phenotype in Koreans. | Two novel mutations in SASH1 identified in a familial and a sporadic generalized lentiginosis phenotype in Koreans. Kim JY, Kwon IJ, Lee SE. | 10/30/2023 |
SASH1: A Novel Eph Receptor Partner and Insights into SAM-SAM Interactions. | SASH1: A Novel Eph Receptor Partner and Insights into SAM-SAM Interactions. Ding Y, Chen Q, Shan H, Liu J, Lv C, Wang Y, Yuan L, Chen Y, Wang Z, Yin Y, Xiao K, Li J, Liu W. | 09/15/2023 |
Human Endogenous Retrovirus-H-Derived miR-4454 Inhibits the Expression of DNAJB4 and SASH1 in Non-Muscle-Invasive Bladder Cancer. | Human Endogenous Retrovirus-H-Derived miR-4454 Inhibits the Expression of DNAJB4 and SASH1 in Non-Muscle-Invasive Bladder Cancer. Park EG, Lee DH, Kim WR, Lee YJ, Bae WH, Kim JM, Shin HJ, Ha H, Yi JM, Cho SG, Choi YH, Leem SH, Cha HJ, Kim SW, Kim HS., Free PMC Article | 08/9/2023 |
Genetic and phenotypic heterogeneity of multiple lentigines and precise diagnosis in four Chinese families with multiple lentigines. | Genetic and phenotypic heterogeneity of multiple lentigines and precise diagnosis in four Chinese families with multiple lentigines. Guo K, Liu JW, Zhang R, Wang R, Ma DL, Zhang X. | 06/9/2023 |
Five novel mutations in SASH1 contribute to lentiginous phenotypes in Japanese families. | Five novel mutations in SASH1 contribute to lentiginous phenotypes in Japanese families. Araki Y, Okamura K, Saito T, Matsumoto K, Natsuga K, Nishimoto J, Funasaka Y, Togawa Y, Suzuki T. | 01/1/2022 |
Two novel SASH1 mutations in Chinese families with dyschromatosis universalis hereditaria. | Two novel SASH1 mutations in Chinese families with dyschromatosis universalis hereditaria. Liu JW, Habulieti X, Wang RR, Ma DL, Zhang X., Free PMC Article | 12/11/2021 |
Paired like homeodomain 1 and SAM and SH3 domain-containing 1 in the progression and prognosis of head and neck squamous cell carcinoma. | Paired like homeodomain 1 and SAM and SH3 domain-containing 1 in the progression and prognosis of head and neck squamous cell carcinoma. Jin Y, Qin X. | 07/3/2021 |
Expression of SASH1 in Preeclampsia and Its Effects on Human Trophoblast. | Expression of SASH1 in Preeclampsia and Its Effects on Human Trophoblast. Liu S, Jiang S, Huang L, Yu Y., Free PMC Article | 05/8/2021 |
SASH1 is a prognostic indicator and potential therapeutic target in non-small cell lung cancer. | SASH1 is a prognostic indicator and potential therapeutic target in non-small cell lung cancer. Burgess JT, Bolderson E, Adams MN, Duijf PHG, Zhang SD, Gray SG, Wright G, Richard DJ, O'Byrne KJ., Free PMC Article | 03/6/2021 |
Involvement of SASH1 in the Maintenance of Stable Cell-Cell Adhesion. | Involvement of SASH1 in the Maintenance of Stable Cell-Cell Adhesion. Ilnitskaya AS, Zhitnyak IY, Gloushankova NA. | 01/9/2021 |
SASH1 suppresses triple-negative breast cancer cell invasion through YAP-ARHGAP42-actin axis. | SASH1 suppresses triple-negative breast cancer cell invasion through YAP-ARHGAP42-actin axis. Jiang K, Liu P, Xu H, Liang D, Fang K, Du S, Cheng W, Ye L, Liu T, Zhang X, Gong P, Shao S, Wang Y, Meng S. | 11/28/2020 |
Findings indicate that miR-130b was highly expressed, while SAM and SH3 domain containing 1 protein (SASH1) was the opposite in both the oesophageal squamous cell carcinoma (ESCC) tissues and cells. | MiR-130b promotes the progression of oesophageal squamous cell carcinoma by targeting SASH1. Zhu Y, Ma Y, Peng H, Gong L, Xiao M, Xiang L, He D, Cao K., Free PMC Article | 04/11/2020 |
These data further confirm that the SLY domain is critical for mediation of melanogenesis and suggest that Y551 may be a mutation hotspot for dyschromatosis universalis hereditaria. The p.M595T is the first heterozygous missense mutation reported in the SH3 domain. | Novel mutations in SASH1 associated with dyschromatosis universalis hereditaria. Zhong WL, Wang HJ, Lin ZM, Yang Y. | 02/8/2020 |
SASH1 is an inhibitor of CRKL-mediated SRC signaling. | The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer. Franke FC, Müller J, Abal M, Medina ED, Nitsche U, Weidmann H, Chardonnet S, Ninio E, Janssen KP., Free PMC Article | 05/4/2019 |
Our clinical findings suggest that downregulated SASH1 expression could be used as an independent biomarker for poor prognosis in gastric carcinoma. | Downregulated SASH1 expression indicates poor clinical prognosis in gastric cancer. Zhou N, Liu C, Wang X, Mao Q, Jin Q, Li P. | 03/9/2019 |
that SASH1 was a target gene of miR-17 | MicroRNA-17 promotes osteosarcoma cells proliferation and migration and inhibits apoptosis by regulating SASH1 expression. Wu D, Zhang H, Ji F, Ding W. | 02/9/2019 |
findings suggested that SASH1 can be useful as a new prognostic marker and therapeutic target in cervical cancer patients. | Downregulation of SASH1 correlates with poor prognosis in cervical cancer. Xie J, Zhang W, Zhang J, Lv QY, Luan YF. | 07/21/2018 |
Data show that SAM and SH3 domain containing 1 protein (SASH1) binds with mitogen-activated protein kinase kinase 2 (MAP2K2), and SASH1 mutations promote binding between SASH1 and MAP2K2. | p53 regulates ERK1/2/CREB cascade via a novel SASH1/MAP2K2 crosstalk to induce hyperpigmentation. Zhou D, Kuang Z, Zeng X, Wang K, Ma J, Luo H, Chen M, Li Y, Zeng J, Li S, Luan F, He Y, Dai H, Liu B, Li H, He L, Xing Q., Free PMC Article | 06/9/2018 |
SASH1 is prognostic in breast cancer and could have subtype-dependent effects on breast cancer progression. | SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer. Burgess JT, Bolderson E, Saunus JM, Zhang SD, Reid LE, McNicol AM, Lakhani SR, Cuff K, Richard K, Richard DJ, O'Byrne KJ., Free PMC Article | 03/3/2018 |
SASH1 may inhibit hepatocarcinoma cell invasion and metastasis through down-regulating the Shh-Gli1 and PI3K-AKT pathways | Involvement of PI3K/Akt pathway in the inhibition of hepatocarcinoma cell invasion and metastasis induced by SASH1 through downregulating Shh-Gli1 signaling. Sun C, Zhang Z, He P, Zhou Y, Xie X. | 11/25/2017 |
Case Report: SASH1 missense mutation in a Chinese Family with multiple lentigines. | A Novel De novo Mutation of the SASH1 Gene in a Chinese Family with Multiple Lentigines. Wang J, Zhang J, Li X, Wang Z, Lei D, Wang G, Li J, Zhang S, Li Z, Li M. | 11/11/2017 |
SASH1 acts through NOTCH1 and its inhibitor DLK1 in a three-dimensional model of lumenogenesis involving CEACAM1. | The adaptor SASH1 acts through NOTCH1 and its inhibitor DLK1 in a 3D model of lumenogenesis involving CEACAM1. Stubblefield K, Chean J, Nguyen T, Chen CJ, Shively JE., Free PMC Article | 10/14/2017 |
SASH1 is cleaved by caspase-3 following Ultraviolet C-induced apoptosis. | Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response. Burgess JT, Bolderson E, Adams MN, Baird AM, Zhang SD, Gately KA, Umezawa K, O'Byrne KJ, Richard DJ., Free PMC Article | 09/2/2017 |