| Blockade of BLyS inhibits B-cell responses and antibody production for the prevention of chronic transplant rejection. | Blockade of BLyS inhibits B-cell responses and antibody production for the prevention of chronic transplant rejection.
Liao T, Shi X, Han F, Wang Y, Zeng W, Liu R, Yan Z, Xia R, Huang Z, Xu J, Miao Y. | 03/18/2024 |
| An unappreciated cell survival-independent role for BAFF initiating chronic lymphocytic leukemia. | An unappreciated cell survival-independent role for BAFF initiating chronic lymphocytic leukemia.
Ullah MA, Garcillán B, Whitlock E, Figgett WA, Infantino S, Eslami M, Yang S, Rahman MA, Sheng YH, Weber N, Schneider P, Tam CS, Mackay F., Free PMC Article | 03/14/2024 |
| Transcriptome analysis of renal ischemia/reperfusion (I/R) injury in BAFF and BAFF-R deficient mice. | Transcriptome analysis of renal ischemia/reperfusion (I/R) injury in BAFF and BAFF-R deficient mice.
Möckel T, Boegel S, Schwarting A., Free PMC Article | 10/26/2023 |
| BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth. | BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth.
Doll JR, Moreno-Fernandez ME, Stankiewicz TE, Wayland JL, Wilburn A, Weinhaus B, Chougnet CA, Giordano D, Cappelletti M, Presicce P, Kallapur SG, Salomonis N, Tilburgs T, Divanovic S., Free PMC Article | 10/6/2023 |
| B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease. | B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease.
Giordano D, Kuley R, Draves KE, Elkon KB, Giltiay NV, Clark EA., Free PMC Article | 03/21/2023 |
| B Cell and T Cell Dissimilarities in BAFF-Deficient versus BR3-Deficient C57BL/6 Mice. | B Cell and T Cell Dissimilarities in BAFF-Deficient versus BR3-Deficient C57BL/6 Mice.
Stohl W, Yu N, Wu Y. | 12/3/2022 |
| BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment. | BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment.
Liu W, Stachura P, Xu HC, Váraljai R, Shinde P, Ganesh NU, Mack M, Van Lierop A, Huang A, Sundaram B, Lang KS, Picard D, Fischer U, Remke M, Homey B, Roesch A, Häussinger D, Lang PA, Borkhardt A, Pandyra AA., Free PMC Article | 02/19/2022 |
| Possible interplay between estrogen and the BAFF may modify thyroid activity in Graves' disease. | Possible interplay between estrogen and the BAFF may modify thyroid activity in Graves' disease.
Cheng CW, Fang WF, Tang KT, Lin JD., Free PMC Article | 01/22/2022 |
| DYRK1a mediates BAFF-induced noncanonical NF-kappaB activation to promote autoimmunity and B-cell leukemogenesis. | DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis.
Li Y, Xie X, Jie Z, Zhu L, Yang JY, Ko CJ, Gao T, Jain A, Jung SY, Baran N, Konopleva MY, Cheng X, Sun SC., Free PMC Article | 01/8/2022 |
| BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation. | BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation.
Jia W, Poe JC, Su H, Anand S, Matsushima GK, Rathmell JC, Maillard I, Radojcic V, Imai K, Reyes NJ, Cardona DM, Li Z, Suthers AN, Curry-Chisolm IM, DiCioccio RA, Saban DR, Chen BJ, Chao NJ, Sarantopoulos S., Free PMC Article | 12/11/2021 |
| B Cell-Activating Factor Antagonism Attenuates the Growth of Experimental Abdominal Aortic Aneurysm. | B Cell-Activating Factor Antagonism Attenuates the Growth of Experimental Abdominal Aortic Aneurysm.
Spinosa MD, Montgomery WG, Lempicki M, Srikakulapu P, Johnsrude MJ, McNamara CA, Upchurch GR Jr, Ailawadi G, Leitinger N, Meher AK., Free PMC Article | 12/11/2021 |
| B cell activating factor (BAFF) from neutrophils and dendritic cells is required for protective B cell responses against Salmonella typhimurium infection. | B cell activating factor (BAFF) from neutrophils and dendritic cells is required for protective B cell responses against Salmonella typhimurium infection.
Kuley R, Draves KE, Fuller DH, Giltiay NV, Clark EA, Giordano D., Free PMC Article | 12/4/2021 |
| Long-term exposure to monoclonal anti-TNF is associated with an increased risk of lymphoma in BAFF-transgenic mice. | Long-term exposure to monoclonal anti-TNF is associated with an increased risk of lymphoma in BAFF-transgenic mice.
Nocturne G, Ly B, Paoletti A, Pascaud J, Seror R, Nicco C, Mackay F, Vincent FB, Lazure T, Ferlicot S, Stimmer L, Pascal Q, Roulland S, Krzysiek R, Hacein-Bey S, Batteux F, Mariette X., Free PMC Article | 12/4/2021 |
| B-cells expressing NgR1 and NgR3 are localized to EAE-induced inflammatory infiltrates and are stimulated by BAFF. | B-cells expressing NgR1 and NgR3 are localized to EAE-induced inflammatory infiltrates and are stimulated by BAFF.
Bakhuraysah MM, Theotokis P, Lee JY, Alrehaili AA, Aui PM, Figgett WA, Azari MF, Abou-Afech JP, Mackay F, Siatskas C, Alderuccio F, Strittmatter SM, Grigoriadis N, Petratos S., Free PMC Article | 11/22/2021 |
| Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival. | Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival.
Müller-Winkler J, Mitter R, Rappe JCF, Vanes L, Schweighoffer E, Mohammadi H, Wack A, Tybulewicz VLJ., Free PMC Article | 09/11/2021 |
| A BAFF/APRIL axis regulates obesogenic diet-driven weight gain. | A BAFF/APRIL axis regulates obesogenic diet-driven weight gain.
Chan CC, Harley ITW, Pfluger PT, Trompette A, Stankiewicz TE, Allen JL, Moreno-Fernandez ME, Damen MSMA, Oates JR, Alarcon PC, Doll JR, Flick MJ, Flick LM, Sanchez-Gurmaches J, Mukherjee R, Karns R, Helmrath M, Inge TH, Weisberg SP, Pamp SJ, Relman DA, Seeley RJ, Tschöp MH, Karp CL, Divanovic S., Free PMC Article | 06/19/2021 |
| BAFF Blockade Attenuates Inflammatory Responses and Intestinal Barrier Dysfunction in a Murine Endotoxemia Model. | BAFF Blockade Attenuates Inflammatory Responses and Intestinal Barrier Dysfunction in a Murine Endotoxemia Model.
Quan R, Chen C, Yan W, Zhang Y, Zhao X, Fu Y., Free PMC Article | 06/5/2021 |
| BST-2/Tetherin is involved in BAFF-enhanced proliferation and survival via canonical NF-kappaB signaling in neoplastic B-lymphoid cells. | BST-2/Tetherin is involved in BAFF-enhanced proliferation and survival via canonical NF-κB signaling in neoplastic B-lymphoid cells.
Fu J, Shi H, Zhan T, Li H, Ye L, Xie L, Wang Z, Wang B, Zheng L. | 05/1/2021 |
| B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure. | B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure.
Nascimento M, Huot-Marchand S, Gombault A, Panek C, Bourinet M, Fanny M, Savigny F, Schneider P, Le Bert M, Ryffel B, Riteau N, Quesniaux VFJ, Couillin I., Free PMC Article | 04/24/2021 |
| B-Cell-Activating Factor Depletion Ameliorates Aging-Dependent Insulin Resistance via Enhancement of Thermogenesis in Adipose Tissues. | B-Cell-Activating Factor Depletion Ameliorates Aging-Dependent Insulin Resistance via Enhancement of Thermogenesis in Adipose Tissues.
Kim B, Hyun CK., Free PMC Article | 02/20/2021 |
| BAFF Produced by Neutrophils and Dendritic Cells Is Regulated Differently and Has Distinct Roles in Antibody Responses and Protective Immunity against West Nile Virus. | BAFF Produced by Neutrophils and Dendritic Cells Is Regulated Differently and Has Distinct Roles in Antibody Responses and Protective Immunity against West Nile Virus.
Giordano D, Kuley R, Draves KE, Roe K, Holder U, Giltiay NV, Clark EA., Free PMC Article | 11/21/2020 |
| Depletion of B cell-activating factor attenuates hepatic fat accumulation in a murine model of nonalcoholic fatty liver disease. | Depletion of B cell-activating factor attenuates hepatic fat accumulation in a murine model of nonalcoholic fatty liver disease.
Nakamura Y, Abe M, Kawasaki K, Miyake T, Watanabe T, Yoshida O, Hirooka M, Matsuura B, Hiasa Y., Free PMC Article | 08/15/2020 |
| The role of BAFF in the development of SLE-like disease may be dispensable as long as B cell survival is preserved via a BAFF-independent pathway. This may help explain the limited and variable clinical success with BAFF antagonists in human SLE. Thus, NZM.Baff(-/-) .Bcl2(Tg) mice may serve as a powerful murine model for the study of BAFF-independent SLE | Development of Murine Systemic Lupus Erythematosus in the Absence of BAFF.
Stohl W, Yu N, Chalmers S, Putterman C, Jacob CO., Free PMC Article | 05/9/2020 |
| by separably programming proliferation, survival and Germinal center phenotype acquisition, IL-4, BAFF and IL-21 drive distinct components of activated B cell fate. | BAFF, IL-4 and IL-21 separably program germinal center-like phenotype acquisition, BCL6 expression, proliferation and survival of CD40L-activated B cells in vitro.
Robinson MJ, Pitt C, Brodie EJ, Valk AM, O'Donnell K, Nitschke L, Jones S, Tarlinton DM. | 04/18/2020 |
| These results suggest that the degree of BAFF contribution to antibody production during Leishmania infection is variable depending on the type of infection and even on the type of antigen in a given infection | Variable dependency on BAFF in IgG antibody production during Leishmania infection.
Azuma N, Omachi S, Hanazawa W, Morimoto A, Sanjoba C, Matsumoto Y, Fujii W, Goto Y. | 03/14/2020 |