Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia. | Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia. Chang R, Su Y, Kong H, Wang F, Xing Y, Jiang L, Xin H. | 02/23/2024 |
Synergistic effects of T-2 toxin and selenium deficiency exacerbate renal fibrosis through modulation of the ERalpha/PI3K/Akt signaling pathway. | Synergistic effects of T-2 toxin and selenium deficiency exacerbate renal fibrosis through modulation of the ERα/PI3K/Akt signaling pathway. Liu H, Lin X, Chilufya MM, Qiao L, Bao M, Wen X, Xiang R, He H, Li M, Han J. | 01/31/2024 |
GMFB/AKT/TGF-beta3 in Muller cells mediated early retinal degeneration in a streptozotocin-induced rat diabetes model. | GMFB/AKT/TGF-β3 in Müller cells mediated early retinal degeneration in a streptozotocin-induced rat diabetes model. Zhu T, Li Y, Zhu L, Xu J, Feng Z, Chen H, Shi S, Liu C, Ou Q, Gao F, Zhang J, Jin C, Xu J, Li J, Zhang J, Bi Y, Xu GT, Wang J, Tian H, Lu L. | 01/17/2024 |
PD-L1 and AKT Overexpressing Adipose-Derived Mesenchymal Stem Cells Enhance Myocardial Protection by Upregulating CD25[+] T Cells in Acute Myocardial Infarction Rat Model. | PD-L1 and AKT Overexpressing Adipose-Derived Mesenchymal Stem Cells Enhance Myocardial Protection by Upregulating CD25(+) T Cells in Acute Myocardial Infarction Rat Model. Lin YK, Hsiao LC, Wu MY, Chen YF, Lin YN, Chang CM, Chung WH, Chen KW, Lu CR, Chen WY, Chang SS, Shyu WC, Lee AS, Chen CH, Jeng LB, Chang KC., Free PMC Article | 01/16/2024 |
Silencing PKM2 Attenuates Brain Injury Induced by Status Epilepticus by Inhibiting the AKT/mTOR Pathway and the NLRP3 Inflammasome. | Silencing PKM2 Attenuates Brain Injury Induced by Status Epilepticus by Inhibiting the AKT/mTOR Pathway and the NLRP3 Inflammasome. Cui X, Jia R, Zhao R, Ma N, Jiang F. | 01/10/2024 |
MiR-182 promotes apoptosis of neural cells in cerebral infarction rats by PI3K/AKT signaling pathway. | MiR-182 promotes apoptosis of neural cells in cerebral infarction rats by PI3K/AKT signaling pathway. Yang R, Zeng C. | 01/5/2024 |
MiR- 211 represses apoptosis of nerve cells in rats with cerebral infarction through PI3K/AKT signaling pathway. | MiR- 211 represses apoptosis of nerve cells in rats with cerebral infarction through PI3K/AKT signaling pathway. Li F, Liu H. | 01/5/2024 |
Hypoxia ischemia results in blood brain barrier damage via AKT/GSK-3beta/CREB pathway in neonatal rats. | Hypoxia ischemia results in blood brain barrier damage via AKT/GSK-3β/CREB pathway in neonatal rats. Liu C, Wang C, Zhang H, Gao X, Xiao P, Yu M, Wang X, Wang X, Wang X. | 12/28/2023 |
miR-107 Attenuates Sepsis-Induced Myocardial Injury by Targeting PTEN and Activating the PI3K/AKT Signaling Pathway. | miR-107 Attenuates Sepsis-Induced Myocardial Injury by Targeting PTEN and Activating the PI3K/AKT Signaling Pathway. Zhang L, Li B, Li W, Jiang J, Chen W, Yang H, Pan D. | 12/18/2023 |
LIPUS-SCs-Exo promotes peripheral nerve regeneration in cavernous nerve crush injury-induced ED rats via PI3K/Akt/FoxO signaling pathway. | LIPUS-SCs-Exo promotes peripheral nerve regeneration in cavernous nerve crush injury-induced ED rats via PI3K/Akt/FoxO signaling pathway. Ye K, Li Z, Yin Y, Zhou J, Li D, Gan Y, Peng D, Xiao M, Zhao L, Dai Y, Tang Y., Free PMC Article | 11/22/2023 |
Bilirubin impacts microglial autophagy via the Akt-mTOR signaling pathway. | Bilirubin impacts microglial autophagy via the Akt-mTOR signaling pathway. Li L, Li S, Pan Z, Zhang Y, Hua Z. | 11/14/2023 |
Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling. | Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling. Wang J, Zhan H, Wang M, Song H, Sun J, Zhao G., Free PMC Article | 10/24/2023 |
Transplantation of endothelial progenitor cells improves myocardial hypertrophy in spontaneously hypertensive rats through HO-1/CREB3/AKT axis. | Transplantation of endothelial progenitor cells improves myocardial hypertrophy in spontaneously hypertensive rats through HO-1/CREB3/AKT axis. Liu H, Liu J, Liu C, Niu X, Liu J. | 09/19/2023 |
ELABELA-APJ-Akt/YAP Signaling Axis: A Novel Mechanism of Aerobic Exercise in Cardioprotection of Myocardial Infarction Rats. | ELABELA-APJ-Akt/YAP Signaling Axis: A Novel Mechanism of Aerobic Exercise in Cardioprotection of Myocardial Infarction Rats. Xi Y, Li Y, Ren W, Bo W, Ma Y, Pan S, Gong DW, Tian Z. | 06/16/2023 |
Inhibition of mitochondrial fission alters neo-intimal hyperplasia via PI3K/Akt signaling in arteriovenous fistulas. | Inhibition of mitochondrial fission alters neo-intimal hyperplasia via PI3K/Akt signaling in arteriovenous fistulas. Wang F, Fan X, Kong J, Wang C, Ma B, Sun W, Ye Z, Liu P, Wen J. | 06/1/2023 |
Netrin-1 attenuates cerebral ischemia/reperfusion injury by limiting mitochondrial ROS and Ca[2+] levels via activation of AKT phosphorylation and mitochondrial m-AAA protease AFG3L2. | Netrin-1 attenuates cerebral ischemia/reperfusion injury by limiting mitochondrial ROS and Ca(2+) levels via activation of AKT phosphorylation and mitochondrial m-AAA protease AFG3L2. Yang X, Liu Y, Zhong W, Li Y, Zhang W. | 02/23/2023 |
The AKT1-FOXO4 axis reciprocally regulates hemochorial placentation. | The AKT1-FOXO4 axis reciprocally regulates hemochorial placentation. Kozai K, Moreno-Irusta A, Iqbal K, Winchester ML, Scott RL, Simon ME, Muto M, Parrish MR, Soares MJ., Free PMC Article | 01/21/2023 |
The protective role of hippocampal LRP1 knockdown involves synaptic plasticity through the promoting microtubule dynamics and activation of Akt/GSK-3beta pathway in depressive rats. | The protective role of hippocampal LRP1 knockdown involves synaptic plasticity through the promoting microtubule dynamics and activation of Akt/GSK-3β pathway in depressive rats. Wang H, Liang L, Yang C, Xiao L, Wang H, Wang G, Zhu Z. | 12/17/2022 |
The Effects of Six Weeks of Endurance Training and CGRP Inhibition on Nrf2 and AKT Expression in the Hippocampal Tissue of Male Wistar Rats. | The Effects of Six Weeks of Endurance Training and CGRP Inhibition on Nrf2 and AKT Expression in the Hippocampal Tissue of Male Wistar Rats. Zare M, Nayebifar S, Aminizadeh S, Vahidian-Rezazadeh M., Free PMC Article | 10/1/2022 |
MiR-107 Aggravates Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-Induced Injury Through Inactivating PI3K-AKT Signalling Pathway by Targeting FGF9/FGF12 in PC12 Cells. | MiR-107 Aggravates Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-Induced Injury Through Inactivating PI3K-AKT Signalling Pathway by Targeting FGF9/FGF12 in PC12 Cells. Fan Q, Wu M, Li C, Li J. | 04/2/2022 |
Inhibited effect of an RGD peptide hydrogel on the expression of beta1-integrin, FAK, and Akt in Tenon's capsule fibroblasts. | Inhibited effect of an RGD peptide hydrogel on the expression of β1-integrin, FAK, and Akt in Tenon's capsule fibroblasts. Chen B, Wu P, Liang L, Zhao C, Wang Z, He L, Zhang R, Xu N. | 03/19/2022 |
Rosmarinic acid inhibits DNA glycation and modulates the expression of Akt1 and Akt3 partially in the hippocampus of diabetic rats. | Rosmarinic acid inhibits DNA glycation and modulates the expression of Akt1 and Akt3 partially in the hippocampus of diabetic rats. Alrubaye A, Motovali-Bashi M, Miroliaei M., Free PMC Article | 02/5/2022 |
Effects and Mechanism of Oxymatrine Combined with Compound Yinchen Granules on the Apoptosis of Hepatocytes through the Akt/FoxO3a/Bim Pathway. | Effects and Mechanism of Oxymatrine Combined with Compound Yinchen Granules on the Apoptosis of Hepatocytes through the Akt/FoxO3a/Bim Pathway. Zhang X, Ge J, Zhu X, Zhang H, Wang Y, Xu T, Jiang W, Zhang B., Free PMC Article | 01/29/2022 |
Silencing Nogo-B improves the integrity of blood-retinal barrier in diabetic retinopathy via regulating Src, PI3K/Akt and ERK pathways. | Silencing Nogo-B improves the integrity of blood-retinal barrier in diabetic retinopathy via regulating Src, PI3K/Akt and ERK pathways. Yang Q, Zhang C, Xie H, Tang L, Liu D, Qiu Q, Luo D, Liu K, Xu JY, Tian H, Lu L, Xu GT, Zhang J. | 01/8/2022 |
Mediation of the Cardioprotective Effects of Mannitol Discovered, with Refutation of Common Protein Kinases. | Mediation of the Cardioprotective Effects of Mannitol Discovered, with Refutation of Common Protein Kinases. Torregroza C, Glashoerster CO, Feige K, Stroethoff M, Raupach A, Heinen A, Hollmann MW, Huhn R., Free PMC Article | 12/25/2021 |