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    Gja1 gap junction protein, alpha 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24392, updated on 6-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    NGF increases Connexin-43 expression and function in pulmonary arterial smooth muscle cells to induce pulmonary artery hyperreactivity.

    NGF increases Connexin-43 expression and function in pulmonary arterial smooth muscle cells to induce pulmonary artery hyperreactivity.
    Cardouat G, Douard M, Bouchet C, Roubenne L, Kmecová Z, Esteves P, Brette F, Guignabert C, Tu L, Campagnac M, Robillard P, Coste F, Delcambre F, Thumerel M, Begueret H, Maurac A, Belaroussi Y, Klimas J, Ducret T, Quignard JF, Vacher P, Baudrimont I, Marthan R, Berger P, Guibert C, Freund-Michel V.

    05/2/2024
    [Inhibition of connexin 43-mediated hemichannel activity promotes odontoblast differentiation of human dental pulp cells induced by lipopolysaccharide].

    [Inhibition of connexin 43-mediated hemichannel activity promotes odontoblast differentiation of human dental pulp cells induced by lipopolysaccharide].
    Zhang AN, Ding CC, Huang LP, Li ST.

    04/10/2024
    Enriched environment alleviates neurological deficits via downregulation of Cx43 after experimental stroke.

    Enriched environment alleviates neurological deficits via downregulation of Cx43 after experimental stroke.
    Chen X, Wang W, Li H, Zhang X.

    12/5/2023
    The potential roles of stress-induced phosphoprotein 1 and connexin 43 in rats with reperfusion arrhythmia.

    The potential roles of stress-induced phosphoprotein 1 and connexin 43 in rats with reperfusion arrhythmia.
    An L, Gao H, Zhong Y, Liu Y, Cao Y, Yi J, Huang X, Wen C, Tong R, Pan Z, Yan X, Liu M, Wang S, Wu H, Hu T., Free PMC Article

    11/3/2023
    MLKL regulates Cx43 ubiquitinational degradation and mediates neuronal necroptosis in ipsilateral thalamus after focal cortical infarction.

    MLKL regulates Cx43 ubiquitinational degradation and mediates neuronal necroptosis in ipsilateral thalamus after focal cortical infarction.
    Tang Y, Chu Q, Xie G, Tan Y, Ye Z, Qin C., Free PMC Article

    11/3/2023
    Cx43 Facilitates Mesenchymal Transition of Endothelial Cells Induced by Shear Stress.

    Cx43 Facilitates Mesenchymal Transition of Endothelial Cells Induced by Shear Stress.
    Zhou E, Zhou J, Bi C, Zhang Z., Free PMC Article

    11/1/2023
    Maladaptive plasticity induced by morphine is mediated by hippocampal astrocytic Connexin-43.

    Maladaptive plasticity induced by morphine is mediated by hippocampal astrocytic Connexin-43.
    Darvishmolla M, Saeedi N, Tavassoli Z, Heysieattalab S, Janahmadi M, Hosseinmardi N.

    09/27/2023
    Inhibition of Connexin43 Improves the Recovery of Spinal Cord Injury Against Ferroptosis via the SLC7A11/GPX4 Pathway.

    Inhibition of Connexin43 Improves the Recovery of Spinal Cord Injury Against Ferroptosis via the SLC7A11/GPX4 Pathway.
    Huang Q, Sha W, Gu Q, Wang J, Zhu Y, Xu T, Xu Z, Yan F, Lin X, Tian S.

    08/19/2023
    Inhibition of Pyk2 Improves Cx43 Intercalated Disc Localization, Infarct Size, and Cardiac Function in Rats With Heart Failure.

    Inhibition of Pyk2 Improves Cx43 Intercalated Disc Localization, Infarct Size, and Cardiac Function in Rats With Heart Failure.
    Zheng L, Spagnol G, Gandhi DR, Sharma K, Kumar V, Patel KP, Sorgen PL.,

    08/19/2023
    Downregulation of cardiac PIASy inhibits Cx43 SUMOylation and ameliorates ventricular arrhythmias in a rat model of myocardial ischemia/reperfusion injury.

    Downregulation of cardiac PIASy inhibits Cx43 SUMOylation and ameliorates ventricular arrhythmias in a rat model of myocardial ischemia/reperfusion injury.
    Wang T, Liu J, Hu C, Wei X, Han L, Zhu A, Wang R, Chen Z, Xia Z, Yao S, Mao W., Free PMC Article

    06/12/2023
    Astrocytes in the spinal cord contributed to acute stress-induced gastric damage via the gap junction protein CX43.

    Astrocytes in the spinal cord contributed to acute stress-induced gastric damage via the gap junction protein CX43.
    Wang Z, Shen Y, Huang C, Wang Y, Zhang X, Guo F, Weng R, Ma X, Sun H.

    05/30/2023
    Impairment of Connexin 43 may initiate cilia decline in syringomyelia.

    Impairment of Connexin 43 may initiate cilia decline in syringomyelia.
    Wang X, Jiang C, Lu C, Ma L, Feng Y, Cui S, Li Q, Li K, Wang X, Jian F.

    05/22/2023
    Cx43 overexpression reduce the incidence of obstructive sleep apnea associated atrial fibrillation via the CaMKgamma/HIF-1 axis.

    Cx43 overexpression reduce the incidence of obstructive sleep apnea associated atrial fibrillation via the CaMKⅡγ/HIF-1 axis.
    Yang X, Sha X, Cao Y, Wang W, Shi J.

    05/8/2023
    Connexin43 overexpression promotes bone regeneration by osteogenesis and angiogenesis in rat glucocorticoid-induced osteonecrosis of the femoral head.

    Connexin43 overexpression promotes bone regeneration by osteogenesis and angiogenesis in rat glucocorticoid-induced osteonecrosis of the femoral head.
    Zhao X, Chen C, Luo Y, Li D, Wang Q, Fang Y, Kang P.

    03/15/2023
    Blocking Cx43 alleviates neuropathic pain in rats with chronic constriction injury via the P2X4 and P38/ERK-P65 pathways.

    Blocking Cx43 alleviates neuropathic pain in rats with chronic constriction injury via the P2X4 and P38/ERK-P65 pathways.
    Xing J, Wang Η, Chen L, Wang H, Huang H, Huang J, Xu C.

    01/14/2023
    GABAergic Regulation of Astroglial Gliotransmission through Cx43 Hemichannels.

    GABAergic Regulation of Astroglial Gliotransmission through Cx43 Hemichannels.
    Jiménez-Dinamarca I, Reyes-Lizana R, Lemunao-Inostroza Y, Cárdenas K, Castro-Lazo R, Peña F, Lucero CM, Prieto-Villalobos J, Retamal MA, Orellana JA, Stehberg J., Free PMC Article

    11/26/2022
    The Ambivalence of Connexin43 Gap Peptides in Cardioprotection of the Isolated Heart against Ischemic Injury.

    The Ambivalence of Connexin43 Gap Peptides in Cardioprotection of the Isolated Heart against Ischemic Injury.
    Falck AT, Lund BA, Johansen D, Lund T, Ytrehus K., Free PMC Article

    09/24/2022
    Connexin 43 hyper-phosphorylation at serine 282 triggers apoptosis in rat cardiomyocytes via activation of mitochondrial apoptotic pathway.

    Connexin 43 hyper-phosphorylation at serine 282 triggers apoptosis in rat cardiomyocytes via activation of mitochondrial apoptotic pathway.
    Fu ZP, Wu LL, Xue JY, Zhang LE, Li C, You HJ, Luo DL., Free PMC Article

    08/6/2022
    Involvement of Hippocampal Astrocytic Connexin-43 in Morphine dependence.

    Involvement of Hippocampal Astrocytic Connexin-43 in Morphine dependence.
    Darvishmolla M, Heysieattalab S, Saeedi N, Hosseinmardi N, Janahmadi M.

    07/30/2022
    CXCR4/CX43 Regulate Diabetic Neuropathic Pain via Intercellular Interactions between Activated Neurons and Dysfunctional Astrocytes during Late Phase of Diabetes in Rats and the Effects of Antioxidant N-Acetyl-L-Cysteine.

    CXCR4/CX43 Regulate Diabetic Neuropathic Pain via Intercellular Interactions between Activated Neurons and Dysfunctional Astrocytes during Late Phase of Diabetes in Rats and the Effects of Antioxidant N-Acetyl-L-Cysteine.
    Zhu D, Fan T, Chen Y, Huo X, Li Y, Liu D, Cai Y, Cheung CW, Tang J, Cui J, Xia Z., Free PMC Article

    07/23/2022
    Intracellular Redistribution of Left Ventricular Connexin 43 Contributes to the Remodeling of Electrical Properties of the Heart in Insulin-resistant Elderly Rats.

    Intracellular Redistribution of Left Ventricular Connexin 43 Contributes to the Remodeling of Electrical Properties of the Heart in Insulin-resistant Elderly Rats.
    Billur D, Olgar Y, Turan B., Free PMC Article

    06/11/2022
    Stress-deprivation induces an up-regulation of versican and connexin-43 mRNA and protein synthesis and increased ADAMTS-1 production in tendon cells in situ.

    Stress-deprivation induces an up-regulation of versican and connexin-43 mRNA and protein synthesis and increased ADAMTS-1 production in tendon cells in situ.
    Egerbacher M, Gardner K, Caballero O, Hlavaty J, Schlosser S, Arnoczky SP, Lavagnino M.

    04/16/2022
    MiR-206 improves intervertebral disk degeneration by targeting GJA1.

    MiR-206 improves intervertebral disk degeneration by targeting GJA1.
    Zhou P, Xu P, Yu W, Li H., Free PMC Article

    03/26/2022
    Development of a refined ex vivo model of peritoneal adhesion formation, and a role for connexin 43 in their development.

    Development of a refined ex vivo model of peritoneal adhesion formation, and a role for connexin 43 in their development.
    Chua JW, Madden L, Lim SBH, Philips ARJ, Becker DL.

    03/19/2022
    HIF-1alpha promotes the proliferation and migration of pulmonary arterial smooth muscle cells via activation of Cx43.

    HIF-1α promotes the proliferation and migration of pulmonary arterial smooth muscle cells via activation of Cx43.
    Han XJ, Zhang WF, Wang Q, Li M, Zhang CB, Yang ZJ, Tan RJ, Gan LJ, Zhang LL, Lan XM, Zhang FL, Hong T, Jiang LP., Free PMC Article

    03/19/2022
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