| S-nitrosylation of EMMPRIN influences the migration of HSCs and MMP activity in liver fibrosis. | S-nitrosylation of EMMPRIN influences the migration of HSCs and MMP activity in liver fibrosis.
Zhu X, Tang Z, Li W, Li X, Iwakiri Y, Liu F., Free PMC Article | 11/7/2023 |
| Knockdown of EMMPRIN (OX47) in MRMT-1 Carcinoma Cells Inhibits Tumor Growth and Decreases Cancer-Induced Bone Destruction and Pain. | Knockdown of EMMPRIN (OX47) in MRMT-1 Carcinoma Cells Inhibits Tumor Growth and Decreases Cancer-Induced Bone Destruction and Pain.
Chen Y, Luan J, Jiang T, Cai D, Sun C, Wang X, Zhao X, Gou X., Free PMC Article | 11/6/2021 |
| CypB-CD147 Signaling Is Involved in Crosstalk between Cartilage and FLS in Collagen-Induced Arthritis. | CypB-CD147 Signaling Is Involved in Crosstalk between Cartilage and FLS in Collagen-Induced Arthritis.
Wang Q, Xu B, Fan K, Wu J, Wang T., Free PMC Article | 08/14/2021 |
| Inflammation suppression by dexamethasone via inhibition of CD147-mediated NF-kappaB pathway in collagen-induced arthritis rats. | Inflammation suppression by dexamethasone via inhibition of CD147-mediated NF-κB pathway in collagen-induced arthritis rats.
Wang Q, Xu B, Fan K, Wu J, Wang T. | 05/1/2021 |
| This study analyzed the direct interaction between CAIV and the two Monocarboxylate transporters (MCTs) chaperones basigin (CD147) and embigin (GP70). In rat CD147, binding of CAIV was mediated by by the positively charged Lys-73. | Membrane-anchored carbonic anhydrase IV interacts with monocarboxylate transporters via their chaperones CD147 and GP70.
Forero-Quintero LS, Ames S, Schneider HP, Thyssen A, Boone CD, Andring JT, McKenna R, Casey JR, Deitmer JW, Becker HM., Free PMC Article | 05/4/2019 |
| Inhibiting the cyclophilin A-CD147 interaction attenuates aAcute pulmonary embolism -associated RV cardiomyocyte injury and dysfunction by suppressing inflammation. | Inhibition of the cyclophilin A-CD147 interaction attenuates right ventricular injury and dysfunction after acute pulmonary embolism in rats.
Lu G, Jia Z, Zu Q, Zhang J, Zhao L, Shi H., Free PMC Article | 02/23/2019 |
| EMMPRIN overexpressing subventricular zone neural progenitor cells invade ischemic cortical tissue more efficiently than controls. | EMMPRIN overexpression in SVZ neural progenitor cells increases their migration towards ischemic cortex.
Kanemitsu M, Tsupykov O, Potter G, Boitard M, Salmon P, Zgraggen E, Gascon E, Skibo G, Dayer AG, Kiss JZ. | 10/7/2017 |
| Upregulation of extracellular matrix metalloproteinase inducer (OX47) in rat dorsal root ganglion contributes to the development of mechanical allodynia after nerve injury. | Upregulation of EMMPRIN (OX47) in Rat Dorsal Root Ganglion Contributes to the Development of Mechanical Allodynia after Nerve Injury.
Wang Q, Sun Y, Ren Y, Gao Y, Tian L, Liu Y, Pu Y, Gou X, Chen Y, Lu Y., Free PMC Article | 09/3/2016 |
| EMMPRIN regulates pressure ulcer healing by controlling the collagen content and angiogenesis rather than MMPs activity. | Local blockage of EMMPRIN impedes pressure ulcers healing in a rat model.
Zhao XL, Luo X, Wang ZX, Yang GL, Liu JZ, Liu YQ, Li M, Chen M, Xia YM, Liu JJ, Qiu SP, Gong XQ., Free PMC Article | 06/11/2016 |
| EMMPRIN expression was increased following fluid percussion injury. EMMPRIN increased expression was temporally correlated with an increase in MMP-9 levels. CD147 and MMP-9 may play a role in vascular injuries after TBI. | Increased CD147 (EMMPRIN) expression in the rat brain following traumatic brain injury.
Wei M, Li H, Shang Y, Zhou Z, Zhang J. | 06/6/2015 |
| EMMPRIN/CD147-regulated metalloproteinases MMP-2 and MMP-14, associated with low MMP-3, appear as the main characteristics of extracellular matrix remodeling in early overused tendons. | Early events of overused supraspinatus tendons involve matrix metalloproteinases and EMMPRIN/CD147 in the absence of inflammation.
Attia M, Huet E, Gossard C, Menashi S, Tassoni MC, Martelly I. | 01/18/2014 |
| basigin may be involved in acute myocardial ischemia following continual ischemia for >30 min. | Expression of basigin in the early phase of acute myocardial ischemia in rats.
Liu Y, Liang WB, Zhang LS, Gao LB, Chen TY, Wang YY, Zhang L. | 11/16/2013 |
| EMMPRIN mediates induction of uterine and vascular matrix metalloproteinases during pregnancy. | EMMPRIN-mediated induction of uterine and vascular matrix metalloproteinases during pregnancy and in response to estrogen and progesterone.
Dang Y, Li W, Tran V, Khalil RA., Free PMC Article | 11/2/2013 |
| EMPRIN and cyclophilin-A play roles in the maturation of dental hard tissue and the formation of a molar eruption pathway. | Differential expression of cyclophilin A and EMMPRIN in developing molars of rats.
Yang SY, Park BI, Kim HJ, Kang JH, Jung NR, Byun JD, Kim MS, Jung JY, Koh JT, Kim WJ, Oh WM, Kim SH. | 09/8/2012 |
| EMMPRIN and VEGF may play a role in radiation injuries of the central nervous system after gamma knife surgery | Increased expression of EMMPRIN and VEGF in the rat brain after gamma irradiation.
Wei M, Li H, Huang H, Xu D, Zhi D, Liu D, Zhang Y., Free PMC Article | 07/14/2012 |
| High Extracellular matrix metalloproteinase inducer is associated with pediatric medulloblastoma. | Extracellular matrix metalloproteinase inducer is a negative prognostic factor of pediatric medulloblastoma.
Chu T, Chen X, Yu J, Xiao J, Fu Z. | 12/24/2011 |
| Basigin was involved in myocardium pathophysiology 30 minutes after myocardial ischemia. | [The expression of Basigin mRNA in early ischemic myocardium and non-ischemic myocardium].
Liu Y, Gao LB, Liang WB, Pan XM, Wang YY, Xue H, Chen TY, Zhang LS, Zhu Y, Zhang L. | 05/28/2011 |
| Extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinases (MMP2/9) as regulators of tumor-host interaction in a spontaneous metastasis model in rats. | Extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinases (MMPs) as regulators of tumor-host interaction in a spontaneous metastasis model in rats.
Donadio AC, Remedi MM, Susperreguy S, Frede S, Gilardoni MB, Tang Y, Pellizas CG, Yan L. | 01/21/2010 |
| These findings suggest potential roles for basement membrane in the transcriptional regulation of tracheal epithelial EMMPRIN. | Role of basement membrane in EMMPRIN/CD147 induction in rat tracheal epithelial cells.
Hosokawa T, Betsuyaku T, Odajima N, Suzuki M, Mochitate K, Nasuhara Y, Nishimura M. | 01/21/2010 |
| These findings suggest that in the myocardium the regulated expression of EMMPRIN is a determinant of MMP activity and may thus play a role in myocardial remodeling. | EMMPRIN mediates beta-adrenergic receptor-stimulated matrix metalloproteinase activity in cardiac myocytes.
Siwik DA, Kuster GM, Brahmbhatt JV, Zaidi Z, Malik J, Ooi H, Ghorayeb G. | 01/21/2010 |
| at low to moderate doses of rt-PA the microvascular basal lamina collagen IV was protected, probably due to inhibition of MMP-2 and MMP-9 by the upregulation of TIMP1, TIMP2, and EMMPRIN | Matrix metalloproteinase (MMP) induction and inhibition at different doses of recombinant tissue plasminogen activator following experimental stroke.
Burggraf D, Martens HK, Dichgans M, Hamann GF. | 01/21/2010 |
| Molecular mass in cauda spermatozoa was approximately 28,000-26,000 Dalton. Capacitation induces minor posttranslational modifications in structure. Facilitates sperm-oocyte interactions. | Molecular modifications of MC31/CE9, a sperm surface molecule, during sperm capacitation and the acrosome reaction in the rat: is MC31/CE9 required for fertilization?
Saxena DK, Toshimori K. | 01/21/2010 |
| These results raise the possibility that the increased expression of EMMPRIN, the increase in MMPs and the damage of the basal lamina following cerebral ischemia are connected and part of a network of related changes. | Matrix metalloproteinase induction by EMMPRIN in experimental focal cerebral ischemia.
Burggraf D, Liebetrau M, Martens HK, Wunderlich N, Jäger G, Dichgans M, Hamann GF. | 01/21/2010 |
| bleomycin-induced lung injury is associated with an increase in CD147 expression and MMP activity, particularly in alveolar epithelial cells. our data exclude any functional interaction between CD147 & alveolar epithelial caveolin-1. | Lack of evidence for caveolin-1 and CD147 interaction before and after bleomycin-induced lung injury.
Barth K, Bläsche R, Kasper M. | 01/21/2010 |
| identified a single leucine (252) as the basolateral targeting motif in the cytoplasmic tail of CD147 | The basolateral targeting signal of CD147 (EMMPRIN) consists of a single leucine and is not recognized by retinal pigment epithelium.
Deora AA, Gravotta D, Kreitzer G, Hu J, Bok D, Rodriguez-Boulan E., Free PMC Article | 01/21/2010 |