| Association of GAB1 gene with asthma susceptibility and the efficacy of inhaled corticosteroids in children. | Association of GAB1 gene with asthma susceptibility and the efficacy of inhaled corticosteroids in children.
Zhang Y, Liu J, Zhi Y, You X, Wei B., Free PMC Article | 12/18/2023 |
| GAB1 as a Marker of Recurrence in Anterior Skull Base Meningioma. | GAB1 as a Marker of Recurrence in Anterior Skull Base Meningioma.
Boetto J, Bielle F, Tran S, Marijon P, Peyre M, Rigau V, Kalamarides M. | 01/28/2023 |
| Circ_0057452 sponges miR-7-5p to promote keloid progression through upregulating GAB1. | Circ_0057452 sponges miR-7-5p to promote keloid progression through upregulating GAB1.
Zhu M, Li Y, Liu L, Zhai X., Free PMC Article | 11/26/2022 |
| Molecular profile reveals immune-associated markers of medulloblastoma for different subtypes. | Molecular profile reveals immune-associated markers of medulloblastoma for different subtypes.
Chen J, Kang Z, Li S, Wang C, Zheng X, Cai Z, Pan L, Chen F, Li W., Free PMC Article | 09/3/2022 |
| Interference of PTK6/GAB1 signaling inhibits cell proliferation, invasion, and migration of cervical cancer cells. | Interference of PTK6/GAB1 signaling inhibits cell proliferation, invasion, and migration of cervical cancer cells.
Li J, Yang N, Tian X, Ouyang L, Jiang M, Zhang S., Free PMC Article | 08/6/2022 |
| Circ_0060531 knockdown ameliorates IL-22-induced keratinocyte damage by binding to miR-330-5p to decrease GAB1 expression. | Circ_0060531 knockdown ameliorates IL-22-induced keratinocyte damage by binding to miR-330-5p to decrease GAB1 expression.
Shi Q, Luo J, Chen W, He Q, Long J, Zhang B. | 06/11/2022 |
| Macromolecular Crowding Induces a Binding Competent Transient Structure in Intrinsically Disordered Gab1. | Macromolecular Crowding Induces a Binding Competent Transient Structure in Intrinsically Disordered Gab1.
Gruber T, Lewitzky M, Machner L, Weininger U, Feller SM, Balbach J. | 05/21/2022 |
| Association of Single-Nucleotide Polymorphisms of Gab1 Gene with Susceptibility to Meningioma in a Northern Chinese Han Population. | Association of Single-Nucleotide Polymorphisms of Gab1 Gene with Susceptibility to Meningioma in a Northern Chinese Han Population.
Chen W, Zhao J, Wu Q, Yan H, Wang X, Nan C, Wu Z, Chen L, Zhao Z., Free PMC Article | 02/5/2022 |
| Circ_0061012 contributes to IL-22-induced proliferation, migration and invasion in keratinocytes through miR-194-5p/GAB1 axis in psoriasis. | Circ_0061012 contributes to IL-22-induced proliferation, migration and invasion in keratinocytes through miR-194-5p/GAB1 axis in psoriasis.
He Q, Liu N, Hu F, Shi Q, Pi X, Chen H, Li J, Zhang B., Free PMC Article | 12/11/2021 |
| FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia. | FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia.
Seda V, Vojackova E, Ondrisova L, Kostalova L, Sharma S, Loja T, Mladonicka Pavlasova G, Zicha D, Kudlickova Peskova M, Krivanek J, Liskova K, Kren L, Benes V, Musilova Litzmanova K, Borsky M, Oppelt J, Verner J, Pospisilova S, Brychtova Y, Panovska A, Tan Z, Zhang S, Doubek M, Amruz Cerna K, Mayer J, Mraz M., Free PMC Article | 12/4/2021 |
| Long non-coding RNA H19 promotes the proliferation, migration and invasion while inhibits apoptosis of hypertrophic scarring fibroblasts by targeting miR-3187-3p/GAB1 axis. | Long non-coding RNA H19 promotes the proliferation, migration and invasion while inhibits apoptosis of hypertrophic scarring fibroblasts by targeting miR-3187-3p/GAB1 axis.
Xiao M, Zou X, Li B, Zhang B. | 11/13/2021 |
| Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways. | Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways.
Hancock MH, Mitchell J, Goodrum FD, Nelson JA., Free PMC Article | 07/17/2021 |
| miR-183-3p suppresses proliferation and migration of keratinocyte in psoriasis by inhibiting GAB1. | miR-183-3p suppresses proliferation and migration of keratinocyte in psoriasis by inhibiting GAB1.
Liu T, Zhang X, Wang Y., Free PMC Article | 06/5/2021 |
| Loss of GRB2 associated binding protein 1 in arteriosclerosis obliterans promotes host autophagy. | Loss of GRB2 associated binding protein 1 in arteriosclerosis obliterans promotes host autophagy.
Ye M, Guo XJ, Kan KJ, Ni QH, Chen JQ, Wang H, Qian X, Xue GH, Deng HY, Zhang L., Free PMC Article | 05/15/2021 |
| Recurrent Fusion of the GRB2 Associated Binding Protein 1 (GAB1) Gene With ABL Proto-oncogene 1 (ABL1) in Benign Pediatric Soft Tissue Tumors. | Recurrent Fusion of the GRB2 Associated Binding Protein 1 (GAB1) Gene With ABL Proto-oncogene 1 (ABL1) in Benign Pediatric Soft Tissue Tumors.
Panagopoulos I, Gorunova L, Andersen K, Tafjord S, Lund-Iversen M, Lobmaier I, Micci F, Heim S., Free PMC Article | 05/8/2021 |
| Increased expression of GAB1 promotes inflammation and fibrosis in systemic sclerosis. | Increased expression of GAB1 promotes inflammation and fibrosis in systemic sclerosis.
Shi X, Liu Q, Zhao H, Lu J, Huang Y, Ma Y, Xia J, Liu M, Tu W, Jin L, Wang J, Zhao Y, Wu W. | 10/31/2020 |
| Gab1 enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner | The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner.
Bongartz H, Gille K, Hessenkemper W, Mandel K, Lewitzky M, Feller SM, Schaper F., Free PMC Article | 07/18/2020 |
| Gab1 expression in Ewing sarcoma, rhabdomyosarcoma and synovial sarcoma may have prognostic significance | Grb2-associated binding protein-1 as a biomarker in bone and soft tissue sarcomas.
Al-Husseinawi E, Bui MM, Ahmed AA. | 02/29/2020 |
| Results identified GAB1 as a direct target of miR-590 in non-small cell lung cancer (NSCLC). Its knockdown had the same effect as overexpression of miR-590 in NSCLC. Moreover, its overexpression partially reversed the suppressive effect of miR-590 on NSCLC. | MicroRNA-590-5p suppresses the proliferation and invasion of non-small cell lung cancer by regulating GAB1.
Xu BB, Gu ZF, Ma M, Wang JY, Wang HN. | 01/18/2020 |
| Modifier variant of METTL13 suppresses human GAB1-associated profound deafness. | Modifier variant of METTL13 suppresses human GAB1-associated profound deafness.
Yousaf R, Ahmed ZM, Giese AP, Morell RJ, Lagziel A, Dabdoub A, Wilcox ER, Riazuddin S, Friedman TB, Riazuddin S., Free PMC Article | 09/14/2019 |
| Gab1 is associated with angiogenesis function of EA.hy926 endothelium cells via PI3K-Akt signaling pathway | Scaffolding adapter protein Gab1 impairs bFGF-induced bio-activity via affecting PI3K-AKT pathway.
Zhang JC, Li WX, Wu L, Liu X, Zhang L. | 06/22/2019 |
| Our findings indicate that elevated expression of Gab1 promotes Breast cancer metastasis by dissociating the PAR complex that leads to EMT, implicating a role of Gab1 as a potential biomarker of metastatic Breast cancer. Moreover, inhibition of Gab1 expression might be a promising therapeutic strategy for Breast cancer metastasis | Elevated expression of Gab1 promotes breast cancer metastasis by dissociating the PAR complex.
Wang X, Peng J, Yang Z, Zhou PJ, An N, Wei L, Zhu HH, Lu J, Fang YX, Gao WQ., Free PMC Article | 04/20/2019 |
| miR-5582-5p induced apoptosis and cell cycle arrest in cancer cells, but not in normal cells. GAB1, SHC1, and CDK2 were identified as direct targets of miR-5582-5p. | Novel miR-5582-5p functions as a tumor suppressor by inducing apoptosis and cell cycle arrest in cancer cells through direct targeting of GAB1, SHC1, and CDK2.
An HJ, Kwak SY, Yoo JO, Kim JS, Bae IH, Park MJ, Cho MY, Kim J, Han YH. | 03/30/2019 |
| These results suggested that Gab1 induced malignant progression of oral squamous carcinoma cells. | Knockdown of Gab1 Inhibits Cellular Proliferation, Migration, and Invasion in Human Oral Squamous Carcinoma Cells.
Xu L, Li J, Kuang Z, Kuang Y, Wu H., Free PMC Article | 12/29/2018 |
| Gab1 is required for H2O2-induced Akt activation in OB-6 osteoblasts. miR-29a inhibition upregulates Gab1 to protect OB-6cells from H2O2. Gab1 over-expression promotes Akt activation to inhibit H2O2-induced OB-6cell death. | microRNA-29a inhibition induces Gab1 upregulation to protect OB-6 human osteoblasts from hydrogen peroxide.
Ruan JW, Yao C, Bai JY, Zhou XZ. | 12/22/2018 |