| Upregulated calcium-binding tyrosine phosphorylation-regulated protein-a/b regulates cell proliferation and apoptosis and predicts poor prognosis in hepatocellular carcinoma. | Upregulated calcium-binding tyrosine phosphorylation-regulated protein-a/b regulates cell proliferation and apoptosis and predicts poor prognosis in hepatocellular carcinoma.
Yu XN, Guo HY, Liu TT, Zhang GC, Zhu HR, Shi X, Song GQ, Jiang XM, Huang XX, Weng SQ, Dong L, Shen XZ, Huang YQ, Zhu JM. | 07/10/2021 |
| Study of (Co-IP) and reverse co-immunoprecipitation (Co-IP) of CBP86-IV (TSCBP86-IV or CABYR) in human sperm cell lysate identified phosphoglycerate kinase 2 (PGK2) as interacting partner of CABYR. Protein interactions were further confirmed by yeast two-hybrid system. | Testis-specific calcium-binding protein CBP86-IV (CABYR) binds with phosphoglycerate kinase 2 in vitro and in vivo experiment.
Shen S, Li D, Liang J, Wang J. | 01/4/2020 |
| There is downregulation of both ROPN1 and CABYR in asthenozoospermic samples and importantly, a positive correlation between the expression of the two genes, suggesting that ROPN1 and CABYR co-expression is a prerequisite for normal flagellar function and sperm motility. | Molecular study of human sperm RNA: Ropporin and CABYR in asthenozoospermia.
Pelloni M, Paoli D, Majoli M, Pallotti F, Carlini T, Lenzi A, Lombardo F. | 10/27/2018 |
| Low CABYR expression is associated with colon cancer. | Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells.
Chen J, Ding J, Wang Z, Zhu J, Wang X, Du J., Free PMC Article | 10/14/2017 |
| The results demonstrate that depletion of CABYR-a/b sensitizes lung cancer cells to TRAIL-induced apoptosis through YAP/p73-mediated DR5 upregulation. | Depletion of CABYR-a/b sensitizes lung cancer cells to TRAIL-induced apoptosis through YAP/p73-mediated DR5 upregulation.
Xiao Q, Qian Z, Zhang W, Liu J, Hu E, Zhang J, Li M, Wang J, Kong F, Li Y, Wang R, Tan X, He D, Xiao X., Free PMC Article | 01/14/2017 |
| Short hairpin RNA-mediated knockdown of CABYR-a/b significantly inhibited the proliferation of NCI-H460 and A549 cells and resulted in the attenuation of Akt phosphorylation, which is constitutively active in lung cancer cells. | Knockdown of CABYR-a/b increases chemosensitivity of human non-small cell lung cancer cells through inactivation of Akt.
Qian Z, Li M, Wang R, Xiao Q, Wang J, Li M, He D, Xiao X. | 01/17/2015 |
| CABYR-c is highly expressed in hepatocellular carcinoma tissues and may play an oncogenic role in heptocarcinogenesis as well as its progression. | The expression and effects the CABYR-c transcript of CABYR gene in hepatocellular carcinoma.
Li H, Fang L, Xiao X, Shen L. | 04/28/2012 |
| CABYR variants form a complex not only with the scaffolding protein AKAP3 but also with another RII-like domain-containing protein in the sperm fibrous sheath. | CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath.
Li YF, He W, Mandal A, Kim YH, Digilio L, Klotz K, Flickinger CJ, Herr JC, Herr JC., Free PMC Article | 07/16/2011 |
| High CABYR is associated with neoplasms. | Expression of the sperm fibrous sheath protein CABYR in human cancers and identification of α-enolase as an interacting partner of CABYR-a.
Tseng YT, Hsia JY, Chen CY, Lin NT, Chong PC, Yang CY. | 07/16/2011 |
| The expression of NF-kappaB was not significantly affected by silencing CABYR in 293T cells. | CABYR RNAi plasmid construction and NF-κB signal transduction pathway.
Shi LX, He YM, Fang L, Meng HB, Zheng LJ., Free PMC Article | 02/5/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| splice variants containing CR-B are expressed during spermiogenesis and assemble into the fibrous sheath of the principal piece; however, calcium binding occurs only to those CABYR isoforms containing CABYR-A | Translation and assembly of CABYR coding region B in fibrous sheath and restriction of calcium binding to coding region A.
Kim YH, Jha KN, Mandal A, Vanage G, Farris E, Snow PL, Klotz K, Naaby-Hansen S, Flickinger CJ, Herr JC. | 01/21/2010 |
| Northern blot showed that CABYR transcripts were expressed more distinctly in the fetal brain than in the adult brain, suggesting that this protein may play a role during brain development. | Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain.
Hsu HC, Lee YL, Cheng TS, Howng SL, Chang LK, Lu PJ, Hong YR. | 01/21/2010 |
| sequencing, cloning, expression and characterization | CABYR, a novel calcium-binding tyrosine phosphorylation-regulated fibrous sheath protein involved in capacitation.
Naaby-Hansen S, Mandal A, Wolkowicz MJ, Sen B, Westbrook VA, Shetty J, Coonrod SA, Klotz KL, Kim YH, Bush LA, Flickinger CJ, Herr JC. | 01/21/2010 |