| p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation. | p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation.
Yang F, Hu A, Guo Y, Wang J, Li D, Wang X, Jin S, Yuan B, Cai S, Zhou Y, Li Q, Chen G, Gao H, Zheng L, Tong Q., Free PMC Article | 02/26/2022 |
| DNAJC2 is reversely regulated by miR6273p, promoting the proliferation of colorectal cancer. | DNAJC2 is reversely regulated by miR‑627‑3p, promoting the proliferation of colorectal cancer.
Liu H, Li J, Zhao H, Liu X, Ye X., Free PMC Article | 11/22/2021 |
| These findings suggest that ZRF1 plays a crucial role in tumor malignant potential through its overexpression and highlight its usefulness as a prognostic factor and potential therapeutic target in gastric cancer | Overexpression of ZRF1 is related to tumor malignant potential and a poor outcome of gastric carcinoma.
Imamura T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Ohashi T, Kiuchi J, Nishibeppu K, Kosuga T, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E. | 10/27/2018 |
| Unexplored functions of ZRF1-mediated remodeling in replication and double strand break repair are discussed. | On-site remodeling at chromatin: How multiprotein complexes are rebuilt during DNA repair and transcriptional activation.
Papadopoulou T, Richly H. | 09/23/2017 |
| In response to UV irradiation, DICER is recruited to chromatin in a ZRF1-mediated manner. The H2A-ubiquitin binding protein ZRF1 and DICER together impact on the chromatin conformation via PARP1. | DICER and ZRF1 contribute to chromatin decondensation during nucleotide excision repair.
Chitale S, Richly H., Free PMC Article | 09/23/2017 |
| ZRF1 mediates remodeling of this E3 ligase complex directly at the DNA lesion site. | ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair.
Gracheva E, Chitale S, Wilhelm T, Rapp A, Byrne J, Stadler J, Medina R, Cardoso MC, Richly H., Free PMC Article | 05/20/2017 |
| The antibody response to ZRF1 was higher in sera of patients with invasive ductal carcinoma than in sera of patients with other histological types of breast tumors. | Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades.
Dyachenko L, Havrysh K, Lytovchenko A, Dosenko I, Antoniuk S, Filonenko V, Kiyamova R., Free PMC Article | 02/25/2017 |
| Zrf1 is transcriptional regulator of neural fate downstream of Id1 in embryonic stem cells.During embryonic stem cell differentiation, Id1 levels decrease allowing Zrf1 to activate neural genes. | Direct interaction between Id1 and Zrf1 controls neural differentiation of embryonic stem cells.
Aloia L, Gutierrez A, Caballero JM, Di Croce L., Free PMC Article | 08/1/2015 |
| our data reveal that ZRF1 is a key transcriptional regulator in leukemia progression | ZRF1 controls the retinoic acid pathway and regulates leukemogenic potential in acute myeloid leukemia.
Demajo S, Uribesalgo I, Gutiérrez A, Ballaré C, Capdevila S, Roth M, Zuber J, Martín-Caballero J, Di Croce L. | 01/24/2015 |
| Zrf1 plays an essential role in neural progenitor cell generation and maintenance | Zrf1 is required to establish and maintain neural progenitor identity.
Aloia L, Di Stefano B, Sessa A, Morey L, Santanach A, Gutierrez A, Cozzuto L, Benitah SA, Graf T, Broccoli V, Di Croce L., Free PMC Article | 03/15/2014 |
| ZRF1 regulates the INK4-ARF locus during cellular proliferation and senescence, and alterations in ZRF1 may contribute to tumorigenesis. | ZRF1 controls oncogene-induced senescence through the INK4-ARF locus.
Ribeiro JD, Morey L, Mas A, Gutierrez A, Luis NM, Mejetta S, Richly H, Benitah SA, Keyes WM, Di Croce L. | 06/22/2013 |
| the majority of AML patients elicited a humoral immune response against the tumor antigen MPP11 | M-phase phosphoprotein 11 is a highly immunogenic tumor antigen in patients with acute myeloid leukemia.
Siegel S, Wirth S, Schweizer M, Schmitz N, Zeis M. | 07/14/2012 |
| describe a novel epitope derived from the MPP11 antigen that has been recognized by human CD8+ CTL | Identification of a novel peptide derived from the M-phase phosphoprotein 11 (MPP11) leukemic antigen recognized by human CD8+ cytotoxic T lymphocytes.
Al Qudaihi G, Lehe C, Dickinson A, Eltayeb K, Rasheed W, Chaudhri N, Aljurf M, Dermime S. | 02/4/2012 |
| At the onset of differentiation, ZRF1 specifically displaces polycomb-repressive complex 1 (PRC1) from chromatin and facilitates transcriptional activation | Transcriptional activation of polycomb-repressed genes by ZRF1.
Richly H, Rocha-Viegas L, Ribeiro JD, Demajo S, Gundem G, Lopez-Bigas N, Nakagawa T, Rospert S, Ito T, Di Croce L. | 01/8/2011 |
| concluded that Mpp11, an ortholog of yeast Zuo, is a ribosome-associated J protein; proposed that in metazoans, ribosome-associated Zuo and Mpp11 orthologs recruit cytosolic Hsc70 to short ribosome-bound nascent chains as they exit the ribosome | Human Mpp11 J protein: ribosome-tethered molecular chaperones are ubiquitous.
Hundley HA, Walter W, Bairstow S, Craig EA. | 01/21/2010 |
| MPP11 is localized to the cytosol and with Hsp70L1, forms the mammalian ribosome-associated complex. | The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex.
Otto H, Conz C, Maier P, Wölfle T, Suzuki CK, Jenö P, Rücknagel P, Stahl J, Rospert S., Free PMC Article | 01/21/2010 |