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    UBE2T ubiquitin conjugating enzyme E2 T [ Homo sapiens (human) ]

    Gene ID: 29089, updated on 27-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    FOXA1/UBE2T Inhibits CD8[+]T Cell Activity by Inducing Mediates Glycolysis in Lung Adenocarcinoma.

    FOXA1/UBE2T Inhibits CD8(+)T Cell Activity by Inducing Mediates Glycolysis in Lung Adenocarcinoma.
    Pu J, Zhang D, Wang B, Zhu P, Yang W, Wang K, Yang Z, Song Q.

    05/24/2024
    UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/beta-Catenin Signaling Pathway.

    UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway.
    Wang Y, Gao G, Wei X, Zhang Y, Yu J., Free PMC Article

    08/25/2023
    USP15-USP7 Axis and UBE2T Differential Expression May Predict Pathogenesis and Poor Prognosis in De Novo Myelodysplastic Neoplasm.

    USP15-USP7 Axis and UBE2T Differential Expression May Predict Pathogenesis and Poor Prognosis in De Novo Myelodysplastic Neoplasm.
    de Carvalho LGA, Komoto TT, Moreno DA, Goes JVC, de Oliveira RTG, de Lima Melo MM, Roa MEGV, Gonçalves PG, Montefusco-Pereira CV, Pinheiro RF, Ribeiro Junior HL., Free PMC Article

    06/30/2023
    Diverse roles of UBE2T in cancer (Review).

    Diverse roles of UBE2T in cancer (Review).
    Ma N, Li Z, Yan J, Liu X, He L, Xie R, Lu X., Free PMC Article

    02/27/2023
    UBE2T promotes glioblastoma malignancy through ubiquitination-mediated degradation of RPL6.

    UBE2T promotes glioblastoma malignancy through ubiquitination-mediated degradation of RPL6.
    Tao X, Wu X, Zhou P, Yu X, Zhao C, Peng X, Zhang K, Shen L, Peng J, Yang L., Free PMC Article

    02/11/2023
    Pan-cancer analysis of UBE2T with a focus on prognostic and immunological roles in lung adenocarcinoma.

    Pan-cancer analysis of UBE2T with a focus on prognostic and immunological roles in lung adenocarcinoma.
    Cao K, Ling X, Jiang X, Ma J, Zhu J., Free PMC Article

    11/19/2022
    UBE2T regulates epithelial-mesenchymal transition through the PI3K-AKT pathway and plays a carcinogenic role in ovarian cancer.

    UBE2T regulates epithelial-mesenchymal transition through the PI3K-AKT pathway and plays a carcinogenic role in ovarian cancer.
    Cui P, Li H, Wang C, Liu Y, Zhang M, Yin Y, Sun Z, Wang Y, Chen X., Free PMC Article

    10/1/2022
    Circ_0000291 contributes to hepatocellular carcinoma tumorigenesis by binding to miR-1322 to up-regulate UBE2T.

    Circ_0000291 contributes to hepatocellular carcinoma tumorigenesis by binding to miR-1322 to up-regulate UBE2T.
    Wang F, Zhong S, Mao C, Jin J, Wang H.

    09/17/2022
    E2F5 promotes proliferation and invasion of gastric cancer through directly upregulating UBE2T transcription.

    E2F5 promotes proliferation and invasion of gastric cancer through directly upregulating UBE2T transcription.
    Li L, Liu J, Huang W.

    07/2/2022
    UBE2T regulates FANCI monoubiquitination to promote NSCLC progression by activating EMT.

    UBE2T regulates FANCI monoubiquitination to promote NSCLC progression by activating EMT.
    Zhang J, Wang J, Wu J, Huang J, Lin Z, Lin X., Free PMC Article

    06/18/2022
    UBE2T promotes proliferation, invasion and glycolysis of breast cancer cells by regualting the PI3K/AKT signaling pathway.

    UBE2T promotes proliferation, invasion and glycolysis of breast cancer cells by regualting the PI3K/AKT signaling pathway.
    Qiao L, Dong C, Ma B.

    06/11/2022
    Knockdown of ubiquitin-conjugating enzyme E2T (UBE2T) suppresses lung adenocarcinoma progression via targeting fibulin-5 (FBLN5).

    Knockdown of ubiquitin-conjugating enzyme E2T (UBE2T) suppresses lung adenocarcinoma progression via targeting fibulin-5 (FBLN5).
    Li Y, Yang X, Lu D., Free PMC Article

    05/14/2022
    miR-498 Targets UBE2T to Inhibit the Proliferation of Malignant Melanoma Cells.

    miR-498 Targets UBE2T to Inhibit the Proliferation of Malignant Melanoma Cells.
    Cao W, Ni L, Li P, Wang QX, Li MM, Huang SH, Dang NN., Free PMC Article

    05/14/2022
    UBE2T-mediated Akt ubiquitination and Akt/beta-catenin activation promotes hepatocellular carcinoma development by increasing pyrimidine metabolism.

    UBE2T-mediated Akt ubiquitination and Akt/β-catenin activation promotes hepatocellular carcinoma development by increasing pyrimidine metabolism.
    Zhu Z, Cao C, Zhang D, Zhang Z, Liu L, Wu D, Sun J., Free PMC Article

    04/16/2022
    UBE2T is upregulated, predicts poor prognosis, and promotes cell proliferation and invasion by promoting epithelial-mesenchymal transition via inhibiting autophagy in an AKT/mTOR dependent manner in ovarian cancer.

    UBE2T is upregulated, predicts poor prognosis, and promotes cell proliferation and invasion by promoting epithelial-mesenchymal transition via inhibiting autophagy in an AKT/mTOR dependent manner in ovarian cancer.
    Huang W, Huang H, Xiao Y, Wang L, Zhang T, Fang X, Xia X., Free PMC Article

    04/16/2022
    MiR-182-5p inhibits the tumorigenesis of clear cell renal cell carcinoma by repressing UBE2T.

    MiR-182-5p inhibits the tumorigenesis of clear cell renal cell carcinoma by repressing UBE2T.
    Wu Y, Zhang C, Peng D, He S, Huang C, Qian J, Zhu W, Feng N, Gong Y, Li X, Zhou L.

    03/5/2022
    miR-543 impairs breast cancer cell phenotypes by targeting and suppressing ubiquitin-conjugating enzyme E2T (UBE2T).

    miR-543 impairs breast cancer cell phenotypes by targeting and suppressing ubiquitin-conjugating enzyme E2T (UBE2T).
    Li L, Li Q., Free PMC Article

    02/19/2022
    DEPDC1B regulates the progression of human chordoma through UBE2T-mediated ubiquitination of BIRC5.

    DEPDC1B regulates the progression of human chordoma through UBE2T-mediated ubiquitination of BIRC5.
    Wang L, Tang L, Xu R, Ma J, Tian K, Liu Y, Lu Y, Wu Z, Zhu X., Free PMC Article

    01/29/2022
    UBE2T Contributes to the Prognosis of Esophageal Squamous Cell Carcinoma.

    UBE2T Contributes to the Prognosis of Esophageal Squamous Cell Carcinoma.
    Wang X, Liu Y, Leng X, Cao K, Sun W, Zhu J, Ma J., Free PMC Article

    01/8/2022
    The interplay of UBE2T and Mule in regulating Wnt/beta-catenin activation to promote hepatocellular carcinoma progression.

    The interplay of UBE2T and Mule in regulating Wnt/β-catenin activation to promote hepatocellular carcinoma progression.
    Ho NPY, Leung CON, Wong TL, Lau EYT, Lei MML, Mok EHK, Leung HW, Tong M, Ng IOL, Yun JP, Ma S, Lee TKW., Free PMC Article

    09/25/2021
    UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma.

    UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma.
    Zhu J, Ao H, Liu M, Cao K, Ma J., Free PMC Article

    09/18/2021
    A novel UBE2T inhibitor suppresses Wnt/beta-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination.

    A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination.
    Yu Z, Jiang X, Qin L, Deng H, Wang J, Ren W, Li H, Zhao L, Liu H, Yan H, Shi W, Wang Q, Luo C, Long B, Zhou H, Sun H, Jiao Z., Free PMC Article

    07/31/2021
    UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.

    UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
    Sun J, Zhu Z, Li W, Shen M, Cao C, Sun Q, Guo Z, Liu L, Wu D., Free PMC Article

    07/10/2021
    A homozygous missense variant in UBE2T is associated with a mild Fanconi anemia phenotype.

    A homozygous missense variant in UBE2T is associated with a mild Fanconi anemia phenotype.
    Schultz-Rogers L, Lach FP, Rickman KA, Ferrer A, Mangaonkar AA, Schwab TL, Schmitz CT, Clark KJ, Dsouza NR, Zimmermann MT, Litzow M, Jacobi N, Klee EW, Smogorzewska A, Patnaik MM., Free PMC Article

    07/10/2021
    Ubiquitin-conjugating enzyme E2T regulates cell proliferation and migration in cholangiocarcinoma.

    Ubiquitin-conjugating enzyme E2T regulates cell proliferation and migration in cholangiocarcinoma.
    Liu F, Zhu C, Gao P, Zheng S, Li C.

    06/19/2021
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