Yin Yang 1 suppresses apoptosis and oxidative stress injury in SH-SY5Y cells by facilitating NR4A1 expression. | Yin Yang 1 suppresses apoptosis and oxidative stress injury in SH-SY5Y cells by facilitating NR4A1 expression. Kang Q, Chai W, Min J, Qu X. | 03/15/2024 |
NR4A1 depletion inhibits colorectal cancer progression by promoting necroptosis via the RIG-I-like receptor pathway. | NR4A1 depletion inhibits colorectal cancer progression by promoting necroptosis via the RIG-I-like receptor pathway. Zhu J, Li J, Yang K, Chen Y, Wang J, He Y, Shen K, Wang K, Shi T, Chen W. | 03/5/2024 |
SOCS3, Transcriptionally Activated by NR4A1, Induces Apoptosis and Extracellular Matrix Degradation of Vaginal Fibroblasts in Pelvic Organ Prolapse. | SOCS3, Transcriptionally Activated by NR4A1, Induces Apoptosis and Extracellular Matrix Degradation of Vaginal Fibroblasts in Pelvic Organ Prolapse. Jin X, Hu Q, Qin M, Yin Y, Xia Z., Free PMC Article | 03/4/2024 |
Hyperinsulinemia impairs decidualization via AKT-NR4A1 signaling: new insight into polycystic ovary syndrome (PCOS)-related infertility. | Hyperinsulinemia impairs decidualization via AKT-NR4A1 signaling: new insight into polycystic ovary syndrome (PCOS)-related infertility. Jiang NX, Zhao WJ, Shen HR, Du DF, Li XL., Free PMC Article | 02/7/2024 |
Evaluation of mRNA Expressions of TOX and NR4As in CD8+ T cells in Acute Leukemia. | Evaluation of mRNA Expressions of TOX and NR4As in CD8+ T cells in Acute Leukemia. Mohammadi M, Asgarian-Omran H, Najafi B, Najafi A, Valadan R, Karami H, Naderisoraki M, Alizadeforoutan M, Shekarriz R, Tehrani M. | 01/16/2024 |
Chemokine receptor CXCR4 interacts with nuclear receptor Nur77 and promote glioma invasion and progression. | Chemokine receptor CXCR4 interacts with nuclear receptor Nur77 and promote glioma invasion and progression. Dai Y, Yu C, Zhou L, Cheng L, Ni H, Liang W. | 01/3/2024 |
Apoptosis of pro-B lymphocytes induced by NR4A1 activation in the presence of gingival fibroblast exosomes and TNFalpha, caspase 8, STAT3, and Akt pathways modulators. | Apoptosis of pro-B lymphocytes induced by NR4A1 activation in the presence of gingival fibroblast exosomes and TNFα, caspase 8, STAT3, and Akt pathways modulators. Amititeloaie C, Chelaru L, Geleţu GL, Sava A, Jităreanu A, Tibeică AM, Costuleanu M., Free PMC Article | 10/28/2023 |
Transient downregulation of NR4A1 leads to impaired osteoblast differentiation through the TGF-ss pathway, and Elesclomol (STA-4783) rescues this phenotype. | Transient downregulation of NR4A1 leads to impaired osteoblast differentiation through the TGF-ß pathway, and Elesclomol (STA-4783) rescues this phenotype. Muthurangan M, Elsafadi M, Siyal A, Kaimkhani ZA, Umrani A, AlMuraikhi NA, Alfayez M, Abdelhady EE, Alqahtani H, Basavarajappa S, Aboul-Soud MAM, Mahmood A. | 10/20/2023 |
ERK5 Cooperates With MEF2C to Regulate Nr4a1 Transcription in MA-10 and MLTC-1 Leydig Cells. | ERK5 Cooperates With MEF2C to Regulate Nr4a1 Transcription in MA-10 and MLTC-1 Leydig Cells. de Mattos K, Dumas FO, Campolina-Silva GH, Belleannée C, Viger RS, Tremblay JJ., | 08/23/2023 |
Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1). | Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1). Lee M, Upadhyay S, Mariyam F, Martin G, Hailemariam A, Lee K, Jayaraman A, Chapkin RS, Lee SO, Safe S., Free PMC Article | 06/7/2023 |
Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation. | Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation. Tao Y, Tang C, Wei J, Shan Y, Fang X, Li Y., Free PMC Article | 05/11/2023 |
NR4A1 mediates NK-cell dysfunction in hepatocellular carcinoma via the IFN-gamma/p-STAT1/IRF1 pathway. | NR4A1 mediates NK-cell dysfunction in hepatocellular carcinoma via the IFN-γ/p-STAT1/IRF1 pathway. Yu W, He J, Wang F, He Q, Shi Y, Tao X, Sun B. | 04/20/2023 |
Silencing lncRNA CDKN2B-AS1 Alleviates Childhood Asthma Progression Through Inhibiting ZFP36 Promoter Methylation and Promoting NR4A1 Expression. | Silencing lncRNA CDKN2B-AS1 Alleviates Childhood Asthma Progression Through Inhibiting ZFP36 Promoter Methylation and Promoting NR4A1 Expression. Chen Z, Fan N, Shen G, Yang J. | 03/24/2023 |
Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice. | Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice. Cai X, Jiang Y, Cao Z, Zhang M, Kong N, Yu L, Tang Y, Kong S, Deng W, Wang H, Sun J, Ding L, Jiang R, Sun H, Yan G., Free PMC Article | 02/22/2023 |
Identification of a Novel Angiogenesis Signalling circSCRG1/miR-1268b/NR4A1 Pathway in Atherosclerosis and the Regulatory Effects of TMP-PF In Vitro. | Identification of a Novel Angiogenesis Signalling circSCRG1/miR-1268b/NR4A1 Pathway in Atherosclerosis and the Regulatory Effects of TMP-PF In Vitro. Yuan R, Xin Q, Ma X, Yu M, Miao Y, Chen K, Cong W., Free PMC Article | 02/14/2023 |
Nur77 Serves as a Potential Prognostic Biomarker That Correlates with Immune Infiltration and May Act as a Good Target for Prostate adenocarcinoma. | Nur77 Serves as a Potential Prognostic Biomarker That Correlates with Immune Infiltration and May Act as a Good Target for Prostate adenocarcinoma. Hu QY, Liu J, Zhang XK, Yang WT, Tao YT, Chen C, Qian YH, Tang JS, Yao XS, Xu YH, Wang JH., Free PMC Article | 02/14/2023 |
Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis. | Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis. Servaas NH, Hiddingh S, Chouri E, Wichers CGK, Affandi AJ, Ottria A, Bekker CPJ, Cossu M, Silva-Cardoso SC, van der Kroef M, Hinrichs AC, Carvalheiro T, Vazirpanah N, Beretta L, Rossato M, Bonte-Mineur F, Radstake TRDJ, Kuiper JJW, Boes M, Pandit A., Free PMC Article | 02/4/2023 |
Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma. | Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma. Li X, Chen Q, Liu J, Lai S, Zhang M, Zhen T, Hu H, Gao X, Wong AST, Zeng JZ., Free PMC Article | 12/31/2022 |
Orphan nuclear receptor NUR77 relieves insulin resistance in HTR-8/SVneo trophoblast cells through activation of autophagy and insulin signaling. | Orphan nuclear receptor NUR77 relieves insulin resistance in HTR-8/SVneo trophoblast cells through activation of autophagy and insulin signaling. Li L, Bai Y, Du R, Tang L, Li L. | 12/3/2022 |
[Nur77 promotes invasion and migration of gastric cancer cells through the NF-kappaB/IL-6 pathway]. | [Nur77 promotes invasion and migration of gastric cancer cells through the NF-κB/IL-6 pathway]. Li W, Shi Y, Guo Y, Tian S., Free PMC Article | 10/15/2022 |
Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1. | Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1. Jin Y, Liu Z, Li Z, Li H, Zhu C, Li R, Zhou T, Fang B., Free PMC Article | 07/23/2022 |
Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages. | Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages. Li Q, Li Y, Huang W, Wang X, Liu Z, Chen J, Fan Y, Peng T, Sadayappan S, Wang Y, Fan GC., Free PMC Article | 07/2/2022 |
Kallistatin/Serpina3c inhibits cardiac fibrosis after myocardial infarction by regulating glycolysis via Nr4a1 activation. | Kallistatin/Serpina3c inhibits cardiac fibrosis after myocardial infarction by regulating glycolysis via Nr4a1 activation. Ji JJ, Qian LL, Zhu Y, Jiang Y, Guo JQ, Wu Y, Yang ZW, Yao YY, Ma GS. | 06/25/2022 |
Essential Roles of the Transcription Factor NR4A1 in Regulatory T Cell Differentiation under the Influence of Immunosuppressants. | Essential Roles of the Transcription Factor NR4A1 in Regulatory T Cell Differentiation under the Influence of Immunosuppressants. Sekiya T, Kasahara H, Takemura R, Fujita S, Kato J, Doki N, Katayama Y, Ozawa Y, Takada S, Eto T, Fukuda T, Ichinohe T, Takanashi M, Onizuka M, Atsuta Y, Okamoto S, Yoshimura A, Takaki S, Mori T. | 05/7/2022 |
Circ_0057583 facilitates brain microvascular endothelial cell injury through modulating miR-204-5p/NR4A1 axis. | Circ_0057583 facilitates brain microvascular endothelial cell injury through modulating miR-204-5p/NR4A1 axis. Wang X, Liu L, Zhang L, Guo J, Yu L, Li T. | 04/16/2022 |