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    HNRNPD heterogeneous nuclear ribonucleoprotein D [ Homo sapiens (human) ]

    Gene ID: 3184, updated on 9-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CircUBE3A(2,3,4,5) promotes adenylate-uridylate-rich binding factor 1 nuclear translocation to suppress prostate cancer metastasis.

    CircUBE3A(2,3,4,5) promotes adenylate-uridylate-rich binding factor 1 nuclear translocation to suppress prostate cancer metastasis.
    Wei Z, Zhang C, Song Y, Han D, Liu J, Song X, Chao F, Wang S, Xu G, Chen G.

    04/12/2024
    AUF1 Recognizes 8-Oxo-Guanosine Embedded in DNA and Stimulates APE1 Endoribonuclease Activity.

    AUF1 Recognizes 8-Oxo-Guanosine Embedded in DNA and Stimulates APE1 Endoribonuclease Activity.
    Malfatti MC, Codrich M, Dalla E, D'Ambrosio C, Storici F, Scaloni A, Tell G.,

    09/19/2023
    AUF1-induced circular RNA hsa_circ_0010467 promotes platinum resistance of ovarian cancer through miR-637/LIF/STAT3 axis.

    AUF1-induced circular RNA hsa_circ_0010467 promotes platinum resistance of ovarian cancer through miR-637/LIF/STAT3 axis.
    Wu Y, Xu M, Feng Z, Wu H, Wu J, Ha X, Wu Y, Chen S, Xu F, Wen H, Li S, Wu X., Free PMC Article

    08/19/2023
    Expression of targets of the RNA-binding protein AUF-1 in human airway epithelium indicates its role in cellular senescence and inflammation.

    Expression of targets of the RNA-binding protein AUF-1 in human airway epithelium indicates its role in cellular senescence and inflammation.
    Salvato I, Ricciardi L, Dal Col J, Nigro A, Giurato G, Memoli D, Sellitto A, Lamparelli EP, Crescenzi MA, Vitale M, Vatrella A, Nucera F, Brun P, Caicci F, Dama P, Stiff T, Castellano L, Idrees S, Johansen MD, Faiz A, Wark PA, Hansbro PM, Adcock IM, Caramori G, Stellato C., Free PMC Article

    07/27/2023
    AUF1 promotes hepatocellular carcinoma progression and chemo-resistance by post-transcriptionally upregulating alpha-fetoprotein expression.

    AUF1 promotes hepatocellular carcinoma progression and chemo-resistance by post-transcriptionally upregulating alpha-fetoprotein expression.
    Zhang J, Zhang T, Guan G, Wen J, Chen CC, Liu J, Duan Y, Liu Y, Chen X.

    05/19/2023
    Circular RNA ARHGAP5 inhibits cisplatin resistance in cervical squamous cell carcinoma by interacting with AUF1.

    Circular RNA ARHGAP5 inhibits cisplatin resistance in cervical squamous cell carcinoma by interacting with AUF1.
    Deng S, Qian L, Liu L, Liu H, Xu Z, Liu Y, Wang Y, Chen L, Zhou Y., Free PMC Article

    04/7/2023
    Hsa_Circ_0000826 inhibits the proliferation of colorectal cancer by targeting AUF1.

    Hsa_Circ_0000826 inhibits the proliferation of colorectal cancer by targeting AUF1.
    Zhang Z, Fan W, Gao Q, Han Y, Ma J, Gao W, Hu Y, Zhu H, Yang R, Wang H, Du B, Zhang Z, Zhong J.

    03/28/2023
    PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing.

    PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing.
    Rajasekaran S, Khan E, Ching SR, Khan M, Siddiqui JK, Gradia DF, Lin C, Bouley SJ, Mercadante DL, Manning AL, Gerber AP, Walker JA, Miles WO., Free PMC Article

    12/17/2022
    The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer.

    The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer.
    Hu H, Zhang H, Xing Y, Zhou Y, Chen J, Li C, Xu J, Guo Y, Wang J, He Q, Liu X, Sheng J, Song E, Wu Y, Huang H.

    12/10/2022
    The RNA-binding protein AUF1 facilitates Akt phosphorylation at the membrane.

    The RNA-binding protein AUF1 facilitates Akt phosphorylation at the membrane.
    Li ML, Ragupathi A, Patel N, Hernandez T, Magsino J, Werlen G, Brewer G, Jacinto E., Free PMC Article

    11/19/2022
    Cleavage of AUF1 by Coxsackievirus B Affects DDX5 Regulatory on Viral Replication through iTRAQ Proteomics Analysis.

    Cleavage of AUF1 by Coxsackievirus B Affects DDX5 Regulatory on Viral Replication through iTRAQ Proteomics Analysis.
    Wang T, Qin Y, Chen J, Chen S, Wu J, Chen X, Chen X, Zhou S, Zou J, Guan J., Free PMC Article

    10/22/2022
    NFkappaB (RelA) mediates transactivation of hnRNPD in oral cancer cells.

    NFκB (RelA) mediates transactivation of hnRNPD in oral cancer cells.
    Kumar V, Kumar A, Kumar M, Lone MR, Mishra D, Chauhan SS., Free PMC Article

    04/23/2022
    E2F1-mediated AUF1 upregulation promotes HCC development and enhances drug resistance via stabilization of AKR1B10.

    E2F1-mediated AUF1 upregulation promotes HCC development and enhances drug resistance via stabilization of AKR1B10.
    Zhang T, Guan G, Zhang J, Zheng H, Li D, Wang W, Lu F, Chen X., Free PMC Article

    04/23/2022
    SChLAP1 contributes to non-small cell lung cancer cell progression and immune evasion through regulating the AUF1/PD-L1 axis.

    SChLAP1 contributes to non-small cell lung cancer cell progression and immune evasion through regulating the AUF1/PD-L1 axis.
    Du Z, Niu S, Wang J, Wu J, Li S, Yi X.

    04/2/2022
    Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer.

    Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer.
    Wang C, Huang H.

    01/1/2022
    Alternatively spliced isoforms of AUF1 regulate a miRNA-mRNA interaction differentially through their YGG motif.

    Alternatively spliced isoforms of AUF1 regulate a miRNA-mRNA interaction differentially through their YGG motif.
    Sänger L, Bender J, Rostowski K, Golbik R, Lilie H, Schmidt C, Behrens SE, Friedrich S., Free PMC Article

    11/27/2021
    A novel lncRNA TCLlnc1 promotes peripheral T cell lymphoma progression through acting as a modular scaffold of HNRNPD and YBX1 complexes.

    A novel lncRNA TCLlnc1 promotes peripheral T cell lymphoma progression through acting as a modular scaffold of HNRNPD and YBX1 complexes.
    Zhao P, Ji MM, Fang Y, Li X, Yi HM, Yan ZX, Cheng S, Xu PP, Janin A, Wang CF, Wang L, Zhao WL., Free PMC Article

    10/16/2021
    HNRNPD interacts with ZHX2 regulating the vasculogenic mimicry formation of glioma cells via linc00707/miR-651-3p/SP2 axis.

    HNRNPD interacts with ZHX2 regulating the vasculogenic mimicry formation of glioma cells via linc00707/miR-651-3p/SP2 axis.
    Yu S, Ruan X, Liu X, Zhang F, Wang D, Liu Y, Yang C, Shao L, Liu Q, Zhu L, Lin Y, Xue Y., Free PMC Article

    09/18/2021
    The overexpression of AUF1 in colorectal cancer predicts a poor prognosis and promotes cancer progression by activating ERK and AKT pathways.

    The overexpression of AUF1 in colorectal cancer predicts a poor prognosis and promotes cancer progression by activating ERK and AKT pathways.
    Tian XY, Li J, Liu TH, Li DN, Wang JJ, Zhang H, Deng ZL, Chen FJ, Cai JP., Free PMC Article

    07/24/2021
    Identification and Verification of Two Novel Differentially Expressed Proteins from Non-neoplastic Mucosa and Colorectal Carcinoma Via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry.

    Identification and Verification of Two Novel Differentially Expressed Proteins from Non-neoplastic Mucosa and Colorectal Carcinoma Via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry.
    Bai Y, Wang J, Gao Z, Dai E.

    04/3/2021
    AUF1 ligand circPCNX reduces cell proliferation by competing with p21 mRNA to increase p21 production.

    AUF1 ligand circPCNX reduces cell proliferation by competing with p21 mRNA to increase p21 production.
    Tsitsipatis D, Grammatikakis I, Driscoll RK, Yang X, Abdelmohsen K, Harris SC, Yang JH, Herman AB, Chang MW, Munk R, Martindale JL, Mazan-Mamczarz K, De S, Lal A, Gorospe M., Free PMC Article

    03/6/2021
    Characterization of novel LncRNA P14AS as a protector of ANRIL through AUF1 binding in human cells.

    Characterization of novel LncRNA P14AS as a protector of ANRIL through AUF1 binding in human cells.
    Ma W, Qiao J, Zhou J, Gu L, Deng D., Free PMC Article

    02/6/2021
    AUF1 stabilizes Nrf2-mRNA.

    Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1.
    Poganik JR, Long MJC, Disare MT, Liu X, Chang SH, Hla T, Aye Y., Free PMC Article

    06/20/2020
    AUF1 knockdown resulted in upregulation of GKN1 expression and promoted GKN1 mRNA decay by binding the 3' untranslated region of GKN1 mRNA H. pylori-induced AUF1 expression was associated with p-ERK activation and CagA.

    Helicobacter pylori inhibits GKN1 expression via the CagA/p-ERK/AUF1 pathway.
    Guo Y, Zhang T, Shi Y, Zhang J, Li M, Lu F, Zhang J, Chen X, Ding S.

    05/30/2020
    AUF1 is involved in the specific degradation of oxidized RNA (REVIEW)

    Two ways of escaping from oxidative RNA damage: Selective degradation and cell death.
    Ishii T, Sekiguchi M.

    03/28/2020
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