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    IFNG interferon gamma [ Homo sapiens (human) ]

    Gene ID: 3458, updated on 22-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-gamma and exerts a therapeutic effect in abortion-prone mice.

    Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone mice.
    Fang Z, Mao J, Huang J, Sun H, Lu X, Lei H, Dong J, Chen S, Wang X., Free PMC Article

    04/22/2024
    Interferon-gamma-induced GBP1 is an inhibitor of human papillomavirus 18.

    Interferon-γ-induced GBP1 is an inhibitor of human papillomavirus 18.
    Xu M, Lin MC, Li ZH., Free PMC Article

    04/22/2024
    Effect of SARS-CoV-2 and Toxoplasma gondii co-infection on IFN-gamma and TNF-alpha expression and its impact on disease severity.

    Effect of SARS-CoV-2 and Toxoplasma gondii co-infection on IFN-γ and TNF-α expression and its impact on disease severity.
    Abdeltawab MSA, Fateen M, Saad El-Din S, Elmessiery RM, Mohammady Mohamed O, Marzouk Sadek K, Medhat E, Hamed AMR.

    03/29/2024
    IFN-gamma induces apoptosis in gemcitabine-resistant pancreatic cancer cells.

    IFN‑γ induces apoptosis in gemcitabine‑resistant pancreatic cancer cells.
    Kong X, Cheng D, Xu X, Zhang Y, Li X, Pan W., Free PMC Article

    03/19/2024
    IFN-gamma decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3beta signaling pathway.

    IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway.
    Song M, Liu X, Shen W, Wang Z, Wu J, Jiang J, Liu Y, Xu T, Bian T, Zhang M, Sun W, Huang M, Ji N., Free PMC Article

    03/5/2024
    Cytokines signatures and susceptibility to cutaneous leishmaniasis in patients from Sistan and Baluchestan province of Iran.

    Cytokines signatures and susceptibility to cutaneous leishmaniasis in patients from Sistan and Baluchestan province of Iran.
    Jahanshahi S, Nejad HR, Kazemi B, Saeedi P.

    03/4/2024
    Spontaneous, persistent, T cell-dependent IFN-gamma release in patients who progress to Long Covid.

    Spontaneous, persistent, T cell-dependent IFN-γ release in patients who progress to Long Covid.
    Krishna BA, Lim EY, Metaxaki M, Jackson S, Mactavous L, NIHR BioResource, Lyons PA, Doffinger R, Bradley JR, Smith KGC, Sinclair J, Matheson NJ, Lehner PJ, Sithole N, Wills MR., Free PMC Article

    02/26/2024
    Human alveolar macrophages display marked hypo-responsiveness to IFN-gamma in both proteomic and gene expression analysis.

    Human alveolar macrophages display marked hypo-responsiveness to IFN-γ in both proteomic and gene expression analysis.
    Thiel BA, Lundberg KC, Schlatzer D, Jarvela J, Li Q, Shaw R, Reba SM, Fletcher S, Beckloff SE, Chance MR, Boom WH, Silver RF, Bebek G., Free PMC Article

    02/12/2024
    Tryptophanyl-Transfer RNA Synthetase Is Involved in a Negative Feedback Loop Mitigating Interferon-gamma-Induced Gene Expression.

    Tryptophanyl-Transfer RNA Synthetase Is Involved in a Negative Feedback Loop Mitigating Interferon-γ-Induced Gene Expression.
    Lazar I, Livneh I, Ciechanover A, Fabre B., Free PMC Article

    02/9/2024
    Evaluation of the presence of Th1 response through T-bet and IFN-gamma immunohistochemical expression in lower lip and oral tongue squamous cell carcinomas.

    Evaluation of the presence of Th1 response through T-bet and IFN-gamma immunohistochemical expression in lower lip and oral tongue squamous cell carcinomas.
    Rodrigues RR, Freitas VS, Alves PM, Almeida Freitas R, Souza LB, Andrade Santos PP.

    01/29/2024
    ISG15-USP18 Dysregulation by Oxidative Stress Promotes IFN-gamma Secretion from CD8+ T Cells in Vitiligo.

    ISG15-USP18 Dysregulation by Oxidative Stress Promotes IFN-γ Secretion from CD8+ T Cells in Vitiligo.
    Lee EJ, Kim JY, Yeo JH, Park S, Bae YJ, Kwon IJ, Seong SH, Lee J, Oh SH.

    01/27/2024
    Increased age-associated B cells in patients with acquired aplastic anemia correlate with IFN-gamma.

    Increased age-associated B cells in patients with acquired aplastic anemia correlate with IFN-γ.
    Solomou EE, Kattamis A, Symeonidis A, Sirinian C, Salamaliki C, Tzanoudaki M, Diamantopoulos P, Plakoula E, Palasopoulou M, Giannakoulas N, Kontandreopoulou CN, Kollia P, Viniou NA, Galanopoulos A, Liossis SN, Vassilopoulos G., Free PMC Article

    01/17/2024
    IFN-gamma-dependent interactions between tissue-intrinsic gammadelta T cells and tissue-infiltrating CD8 T cells limit allergic contact dermatitis.

    IFN-γ-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit allergic contact dermatitis.
    Muñoz-Ruiz M, Llorian M, D'Antuono R, Pavlova A, Mavrigiannaki AM, McKenzie D, García-Cassani B, Iannitto ML, Wu Y, Dart R, Davies D, Jamal-Hanjani M, Jandke A, Ushakov DS, Hayday AC.

    12/20/2023
    COVID-19 patients with high TNF/IFN-gamma levels show hallmarks of PANoptosis, an inflammatory cell death.

    COVID-19 patients with high TNF/IFN-γ levels show hallmarks of PANoptosis, an inflammatory cell death.
    Palacios Y, Ramón-Luing LA, Ruiz A, García-Martínez A, Sánchez-Monciváis A, Barreto-Rodríguez O, Falfán-Valencia R, Pérez-Rubio G, Medina-Quero K, Buendia-Roldan I, Chavez-Galan L.

    12/20/2023
    Inhibitory receptor CD47 binding to plasma TSP1 suppresses NK-cell IFN-gamma production via activating the JAK/STAT3 pathway during HIV infection.

    Inhibitory receptor CD47 binding to plasma TSP1 suppresses NK-cell IFN-γ production via activating the JAK/STAT3 pathway during HIV infection.
    Lang B, Wang M, Zhang Z, Fu Y, Han X, Hu Q, Ding H, Shang H, Jiang Y., Free PMC Article

    12/6/2023
    IFN-gamma in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis.

    IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis.
    Zheng H, Guan X, Meng X, Tong Y, Wang Y, Xie S, Guo L, Lu R., Free PMC Article

    11/29/2023
    Astrocyte interferon-gamma signaling dampens inflammation during chronic central nervous system autoimmunity via PD-L1.

    Astrocyte interferon-gamma signaling dampens inflammation during chronic central nervous system autoimmunity via PD-L1.
    Smith BC, Tinkey RA, Brock OD, Mariam A, Habean ML, Dutta R, Williams JL., Free PMC Article

    11/28/2023
    Granulocyte transfusion during cord blood transplant for relapsed, refractory AML is associated with massive CD8[+] T-cell expansion, significant cytokine release syndrome and induction of disease remission.

    Granulocyte transfusion during cord blood transplant for relapsed, refractory AML is associated with massive CD8(+) T-cell expansion, significant cytokine release syndrome and induction of disease remission.
    Borrill R, Poulton K, Kusyk L, Routledge A, Bonney D, Hanasoge-Nataraj R, Powys M, Mustafa O, Campbell H, Senthil S, Dillon R, Jovanovic J, Morton S, James B, Rao K, Stanworth S, Konkel J, Wynn R.

    11/27/2023
    Performance of interferon-gamma levels may lead to earlier diagnosing macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

    Performance of interferon-gamma levels may lead to earlier diagnosing macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
    Lu M, Teng L, Xu Y, Xu X., Free PMC Article

    11/18/2023
    IFN-gamma: An overlooked cytokine in dermatomyositis with anti-MDA5 antibodies.

    IFN-γ: An overlooked cytokine in dermatomyositis with anti-MDA5 antibodies.
    Thuner J, Coutant F.

    11/13/2023
    A Conserved Domain of HCV E2 Glycoprotein Interacts with Human CD81 and Induces Interferon-Gamma Secretion from Peripheral Blood Mononuclear Cells.

    A Conserved Domain of HCV E2 Glycoprotein Interacts with Human CD81 and Induces Interferon-Gamma Secretion from Peripheral Blood Mononuclear Cells.
    Dai Z, Zeng W, Li G, Shu X.

    11/8/2023
    Higher pro-inflammatory cytokines IL-6 and IFN-gamma are associated with anti-SARS-CoV-2 spike protein-specific seroconversion in renal allograft recipients.

    Higher pro-inflammatory cytokines IL-6 and IFN-γ are associated with anti-SARS-CoV-2 spike protein-specific seroconversion in renal allograft recipients.
    Yadav B, Prasad N, Kushwaha RS, Patel MR, Bhadauria D, Kaul A.

    10/30/2023
    Interferon gamma regulates a complex pro-survival signal network in chronic lymphocytic leukemia.

    Interferon gamma regulates a complex pro-survival signal network in chronic lymphocytic leukemia.
    Chen Y, Shao X, Yang H, Ren L, Cui Y, Zhang W, Macip S, Meng X.

    10/23/2023
    xCT-mediated glutamate excretion in white adipocytes stimulates interferon-gamma production by natural killer cells in obesity.

    xCT-mediated glutamate excretion in white adipocytes stimulates interferon-γ production by natural killer cells in obesity.
    Kim HH, Shim YR, Kim HN, Yang K, Ryu T, Kim K, Choi SE, Kim MJ, Woo C, Chung KPS, Hong SH, Shin H, Suh JM, Jung Y, Hwang GS, Kim W, Kim SH, Eun HS, Seong JK, Jeong WI.

    10/13/2023
    IFN but not IFNalpha increases recognition of insulin defective ribosomal product-derived antigen to amplify islet autoimmunity.

    IFNɣ but not IFNα increases recognition of insulin defective ribosomal product-derived antigen to amplify islet autoimmunity.
    Thomaidou S, Munoz Garcia A, de Lange S, Gan J, van der Slik AR, Hoeben RC, Roep BO, Carlotti F, Zaldumbide A., Free PMC Article

    10/2/2023
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