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    IL12A interleukin 12A [ Homo sapiens (human) ]

    Gene ID: 3592, updated on 3-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Signaling pathways underlying TGF-beta mediated suppression of IL-12A gene expression in monocytes.

    Signaling pathways underlying TGF-β mediated suppression of IL-12A gene expression in monocytes.
    Hourani T, Eivazitork M, Balendran T, Mc Lee K, Hamilton JA, Zhu HJ, Iaria J, Morokoff AP, Luwor RB, Achuthan AA.

    02/20/2024
    Altered Gene Expression of IL-35 and IL-36alpha in the Skin of Patients with Atopic Dermatitis.

    Altered Gene Expression of IL-35 and IL-36α in the Skin of Patients with Atopic Dermatitis.
    Zysk W, Sitko K, Tukaj S, Zaryczańska A, Trzeciak M., Free PMC Article

    01/16/2024
    IL-8 and IL-12p70 are associated with pelvic pain among infertile women with endometriosis.

    IL-8 and IL-12p70 are associated with pelvic pain among infertile women with endometriosis.
    Rahmawati NY, Ahsan F, Santoso B, Mufid AF, Sa'adi A, Dwiningsih SR, Tunjungseto A, Widyanugraha MYA.

    11/8/2023
    Human interleukin-12alpha and EBI3 are cytokines with anti-inflammatory functions.

    Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions.
    Hildenbrand K, Bohnacker S, Menon PR, Kerle A, Prodjinotho UF, Hartung F, Strasser PC, Catici DAM, Rührnößl F, Haslbeck M, Schumann K, Müller SI, da Costa CP, Esser-von Bieren J, Feige MJ., Free PMC Article

    11/1/2023
    A Meta-Analysis of the Association Between Genetic Polymorphisms in IL-12, IL-17, and IL-21 and Risk of Hepatitis B Virus Infection.

    A Meta-Analysis of the Association Between Genetic Polymorphisms in IL-12, IL-17, and IL-21 and Risk of Hepatitis B Virus Infection.
    Wan J, Tang L, Li H, Yang P.

    05/19/2023
    Immunomodulatory effect of IL-35 gene-transfected mesenchymal stem cells on allergic asthma.

    Immunomodulatory effect of IL-35 gene-transfected mesenchymal stem cells on allergic asthma.
    Bao XH, Gao F, Athari SS, Wang H.

    02/11/2023
    [Expression of Tregs and IL-35 in Peripheral Blood of Patients with Newly Diagnosed Acute Myeloid Leukemia].

    [Expression of Tregs and IL-35 in Peripheral Blood of Patients with Newly Diagnosed Acute Myeloid Leukemia].
    Yang PX, Wang P, Fang L, Wang Q.

    12/17/2022
    Interleukin-35 ameliorates cardiovascular disease by suppressing inflammatory responses and regulating immune homeostasis.

    Interleukin-35 ameliorates cardiovascular disease by suppressing inflammatory responses and regulating immune homeostasis.
    Feng J, Wu Y.

    08/20/2022
    Interleukin 35 regulates interleukin 17 expression and T helper 17 in patients with proliferative diabetic retinopathy.

    Interleukin 35 regulates interleukin 17 expression and T helper 17 in patients with proliferative diabetic retinopathy.
    Yan A, Zhang Y, Wang X, Cui Y, Tan W., Free PMC Article

    06/11/2022
    At Embryo Implantation Site IL-35 Secreted by Trophoblast, Polarizing T Cells towards IL-35+ IL-10+ IL-4+ Th2-Type Cells, Could Favour Fetal Allograft Tolerance and Pregnancy Success.

    At Embryo Implantation Site IL-35 Secreted by Trophoblast, Polarizing T Cells towards IL-35+ IL-10+ IL-4+ Th2-Type Cells, Could Favour Fetal Allograft Tolerance and Pregnancy Success.
    Lombardelli L, Logiodice F, Kullolli O, Haller H, Agostinis C, Bulla R, Rukavina D, Piccinni MP., Free PMC Article

    05/28/2022
    Altered CD4+ T cell and cytokine levels in peripheral blood and skin samples from systemic sclerosis patients and IL-35 in CD4+ T cell growth.

    Altered CD4+ T cell and cytokine levels in peripheral blood and skin samples from systemic sclerosis patients and IL-35 in CD4+ T cell growth.
    Yang C, Lei L, Pan J, Zhao C, Wen J, Qin F, Dong F, Wei W.

    03/12/2022
    Interleukin-35 in idiopathic inflammatory myopathies.

    Interleukin-35 in idiopathic inflammatory myopathies.
    Mann H, Kryštůfková O, Zámečník J, Háček J, Hulejová H, Filková M, Vencovský J, Šenolt L.

    01/1/2022
    Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus.

    Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus.
    Reid S, Hagberg N, Sandling JK, Alexsson A, Pucholt P, Sjöwall C, Lerang K, Jönsen A, Gunnarsson I, Syvänen AC, Troldborg AM, Voss A, Bengtsson AA, Molberg Ø, Jacobsen S, Svenungsson E, Rönnblom L, Leonard D., Free PMC Article

    09/25/2021
    Contribution of Interleukin-12A Genotypes to Breast Cancer Risk.

    Contribution of Interleukin-12A Genotypes to Breast Cancer Risk.
    Wang YC, Wang ZH, Shen TC, Chang WS, Huang SZ, Yu CC, Chen JC, Hsiau YC, Yang JS, Tsai CW, Bau DT.

    09/11/2021
    IL-35 promotes EMT through STAT3 activation and induces MET by promoting M2 macrophage polarization in HCC.

    IL-35 promotes EMT through STAT3 activation and induces MET by promoting M2 macrophage polarization in HCC.
    He Y, Pei JH, Li XQ, Chi G.

    08/28/2021
    Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.

    Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.
    Glassman CR, Mathiharan YK, Jude KM, Su L, Panova O, Lupardus PJ, Spangler JB, Ely LK, Thomas C, Skiniotis G, Garcia KC., Free PMC Article

    08/28/2021
    Expressions of IL-12 and its receptors in patients with lumbar disc herniation and their relationship with clinical efficacy.

    Expressions of IL-12 and its receptors in patients with lumbar disc herniation and their relationship with clinical efficacy.
    Wang X, Zhou S, Fan M, Wang P, Fang H, Bian F, Huang T, Du X.

    08/7/2021
    Plasma Level of ADAMTS13 or IL-12 as an Indicator of HBeAg Seroconversion in Chronic Hepatitis B Patients Undergoing m-ETV Treatment.

    Plasma Level of ADAMTS13 or IL-12 as an Indicator of HBeAg Seroconversion in Chronic Hepatitis B Patients Undergoing m-ETV Treatment.
    Yang J, Guo R, Yan D, Lu H, Zhang H, Ye P, Jin L, Diao H, Li L., Free PMC Article

    07/3/2021
    Epigenetic DNA Methylation of EBI3 Modulates Human Interleukin-35 Formation via NFkB Signaling: A Promising Therapeutic Option in Ulcerative Colitis.

    Epigenetic DNA Methylation of EBI3 Modulates Human Interleukin-35 Formation via NFkB Signaling: A Promising Therapeutic Option in Ulcerative Colitis.
    Wetzel A, Scholtka B, Schumacher F, Rawel H, Geisendörfer B, Kleuser B., Free PMC Article

    07/3/2021
    Lower serum interleukin-22 and interleukin-35 levels are associated with disease status in neuromyelitis optica spectrum disorders.

    Lower serum interleukin-22 and interleukin-35 levels are associated with disease status in neuromyelitis optica spectrum disorders.
    Yang H, Han L, Zhou YJ, Ding J, Cai Y, Hong RH, Hao Y, Zhu DS, Shen XF, Guan YT., Free PMC Article

    06/26/2021
    Clinical significance of CC16 and IL-12 in bronchoalveolar lavage fluid of various stages of silicosis.

    Clinical significance of CC16 and IL-12 in bronchoalveolar lavage fluid of various stages of silicosis.
    Zhang S, Jia Q, Song J, Tan Q, Yu G, Guo X, Zhang H.

    06/26/2021
    IL-12 and IL-23-Close Relatives with Structural Homologies but Distinct Immunological Functions.

    IL-12 and IL-23-Close Relatives with Structural Homologies but Distinct Immunological Functions.
    Floss DM, Moll JM, Scheller J., Free PMC Article

    06/19/2021
    Analysis for interaction between interleukin-35 genes polymorphisms and risk factors on susceptibility to coronary heart disease in the Chinese Han population.

    Analysis for interaction between interleukin-35 genes polymorphisms and risk factors on susceptibility to coronary heart disease in the Chinese Han population.
    Li H, Liu YX, Huang JY, Zhu YF, Wang K., Free PMC Article

    06/19/2021
    Association of IL-35 expression and gene polymorphisms in rheumatoid arthritis.

    Association of IL-35 expression and gene polymorphisms in rheumatoid arthritis.
    Xie Q, Xu WD, Pan M, Lan YY, Liu XY, Su LC, Huang AF.

    05/22/2021
    Reduced IL-35 in patients with immune thrombocytopenia.

    Reduced IL-35 in patients with immune thrombocytopenia.
    Sun RJ, Yuan D, Liu SY, Zhu JJ, Shan NN.

    05/22/2021
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