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    ILF3 interleukin enhancer binding factor 3 [ Homo sapiens (human) ]

    Gene ID: 3609, updated on 9-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Deficiency of smooth muscle cell ILF3 alleviates intimal hyperplasia via HMGB1 mRNA degradation-mediated regulation of the STAT3/DUSP16 axis.

    Deficiency of smooth muscle cell ILF3 alleviates intimal hyperplasia via HMGB1 mRNA degradation-mediated regulation of the STAT3/DUSP16 axis.
    Hou YM, Xu BH, Zhang QT, Cheng J, Zhang X, Yang HR, Wang ZY, Wang P, Zhang MX.

    05/1/2024
    Role of ATF3 triggering M2 macrophage polarization to protect against the inflammatory injury of sepsis through ILF3/NEAT1 axis.

    Role of ATF3 triggering M2 macrophage polarization to protect against the inflammatory injury of sepsis through ILF3/NEAT1 axis.
    Wang W, Xu R, He P, Xiong Y, Zhao H, Fu X, Lin J, Ye L., Free PMC Article

    03/8/2024
    Astragaloside IV promotes keratinocyte proliferation and migration through upregulating lncRNA H19 recruited ILF3 to enhance the stability of CDK4 mRNA.

    Astragaloside IV promotes keratinocyte proliferation and migration through upregulating lncRNA H19 recruited ILF3 to enhance the stability of CDK4 mRNA.
    Wang DD, Zhang LZ, Pang CJ, Ye JZ.

    08/16/2023
    E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNA.

    E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNA.
    Shen HM, Zhang D, Xiao P, Qu B, Sun YF., Free PMC Article

    07/21/2023
    PSMD3-ILF3 signaling cascade drives lung cancer cell proliferation and migration.

    PSMD3-ILF3 signaling cascade drives lung cancer cell proliferation and migration.
    Zhang J, Ma Q, Yu Q, Xiao F, Zhang Z, Feng H, Liang C., Free PMC Article

    06/23/2023
    Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing.

    Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing.
    Yan G, Yang J, Li W, Guo A, Guan J, Liu Y.

    05/17/2023
    Prognostic and immunotherapeutic predictive value of interleukin enhancer-binding factor 3 in hepatocellular carcinoma: Integrated bioinformatics and experimental analysis.

    Prognostic and immunotherapeutic predictive value of interleukin enhancer-binding factor 3 in hepatocellular carcinoma: Integrated bioinformatics and experimental analysis.
    Qiu J, Wu X, Luo Y, Yao Y, Zhang X, Pan B, Wang X, Tang N.

    02/4/2023
    Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.

    Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
    Tan J, Sun M, Yin J, Zhou Q, Zhao R, Chen Q, Sun H, Jiang C, Li S, He Y.

    12/3/2022
    RNA binding protein POP7 regulates ILF3 mRNA stability and expression to promote breast cancer progression.

    RNA binding protein POP7 regulates ILF3 mRNA stability and expression to promote breast cancer progression.
    Huang Y, Zheng Y, Yao L, Qiao F, Hou Y, Hu X, Li D, Shao Z., Free PMC Article

    11/12/2022
    NF90 interacts with components of RISC and modulates association of Ago2 with mRNA.

    NF90 interacts with components of RISC and modulates association of Ago2 with mRNA.
    Grasso G, Akkawi C, Franckhauser C, Nait-Saidi R, Bello M, Barbier J, Kiernan R., Free PMC Article

    09/17/2022
    ILF3 represses repeat-derived microRNAs targeting RIG-I mediated type I interferon response.

    ILF3 represses repeat-derived microRNAs targeting RIG-I mediated type I interferon response.
    Chen G, Yang Y, Wu QJ, Cao L, Ruan W, Shao C, Jiang L, Tang P, Ma S, Jiang A, Wang Z, Wu K, Zhang QC, Fu XD, Zhou Y.

    05/14/2022
    ILF3 is responsible for hyperlipidemia-induced arteriosclerotic calcification by mediating BMP2 and STAT1 transcription.

    ILF3 is responsible for hyperlipidemia-induced arteriosclerotic calcification by mediating BMP2 and STAT1 transcription.
    Xie F, Cui QK, Wang ZY, Liu B, Qiao W, Li N, Cheng J, Hou YM, Dong XY, Wang Y, Zhang MX.

    03/19/2022
    Systematic identification of NF90 target RNAs by iCLIP analysis.

    Systematic identification of NF90 target RNAs by iCLIP analysis.
    Lodde V, Floris M, Munk R, Martindale JL, Piredda D, Napodano CMP, Cucca F, Uzzau S, Abdelmohsen K, Gorospe M, Noh JH, Idda ML., Free PMC Article

    01/29/2022
    Long non-coding RNA ILF3-AS1 facilitates hepatocellular carcinoma progression by stabilizing ILF3 mRNA in an m(6)A-dependent manner.

    Long non-coding RNA ILF3-AS1 facilitates hepatocellular carcinoma progression by stabilizing ILF3 mRNA in an m(6)A-dependent manner.
    Bo C, Li N, He L, Zhang S, An Y.

    01/29/2022
    Upregulated long noncoding RNA LincIN promotes tumor progression via the regulation of nuclear factor 90/microRNA7/HOXB13 in esophageal squamous cell carcinoma.

    Upregulated long non‑coding RNA LincIN promotes tumor progression via the regulation of nuclear factor 90/microRNA‑7/HOXB13 in esophageal squamous cell carcinoma.
    Tan Z, Zhou P, Zhu Z, Wang Y, Guo Z, Shen M, Xiao Y, Shen W, Wu D., Free PMC Article

    11/13/2021
    HNRNPA2B1 promotes multiple myeloma progression by increasing AKT3 expression via m6A-dependent stabilization of ILF3 mRNA.

    HNRNPA2B1 promotes multiple myeloma progression by increasing AKT3 expression via m6A-dependent stabilization of ILF3 mRNA.
    Jiang F, Tang X, Tang C, Hua Z, Ke M, Wang C, Zhao J, Gao S, Jurczyszyn A, Janz S, Beksac M, Zhan F, Gu C, Yang Y., Free PMC Article

    09/18/2021
    circACTA2 mediates Ang II-induced VSMC senescence by modulation of the interaction of ILF3 with CDK4 mRNA.

    circACTA2 mediates Ang II-induced VSMC senescence by modulation of the interaction of ILF3 with CDK4 mRNA.
    Ma Y, Zheng B, Zhang XH, Nie ZY, Yu J, Zhang H, Wang DD, Shi B, Bai Y, Yang Z, Wen JK., Free PMC Article

    07/31/2021
    TMEM98 mRNA promotes proliferation and invasion of gastric cells by directly interacting with NF90 protein.

    TMEM98 mRNA promotes proliferation and invasion of gastric cells by directly interacting with NF90 protein.
    Ao X, Li X, Chen Y, Zang Z, Guo W, Liang J.

    06/26/2021
    ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer.

    ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer.
    Li K, Wu JL, Qin B, Fan Z, Tang Q, Lu W, Zhang H, Xing F, Meng M, Zou S, Wei W, Chen H, Cai J, Wang H, Zhang H, Cai J, Fang L, Bian X, Chen C, Lan P, Ghesquière B, Fang L, Lee MH., Free PMC Article

    05/29/2021
    NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.

    NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.
    Nourreddine S, Lavoie G, Paradis J, Ben El Kadhi K, Méant A, Aubert L, Grondin B, Gendron P, Chabot B, Bouvier M, Carreno S, Roux PP.

    05/22/2021
    LncRNA MEG3 contributes to adenosine-induced cytotoxicity in hepatoma HepG2 cells by downregulated ILF3 and autophagy inhibition via regulation PI3K-AKT-mTOR and beclin-1 signaling pathway.

    LncRNA MEG3 contributes to adenosine-induced cytotoxicity in hepatoma HepG2 cells by downregulated ILF3 and autophagy inhibition via regulation PI3K-AKT-mTOR and beclin-1 signaling pathway.
    Pu Z, Wu L, Guo Y, Li G, Xiang M, Liu L, Zhan H, Zhou X, Tan H.

    09/19/2020
    NF90 modulates processing of a subset of human pri-miRNAs.

    NF90 modulates processing of a subset of human pri-miRNAs.
    Grasso G, Higuchi T, Mac V, Barbier J, Helsmoortel M, Lorenzi C, Sanchez G, Bello M, Ritchie W, Sakamoto S, Kiernan R., Free PMC Article

    09/12/2020
    NF90 contributes to repressing the immune response in cells responding to P. falciparum infection.

    NF90 regulation of immune factor expression in response to malaria antigens.
    Idda ML, Lodde V, Galleri G, Martindale JL, Munk R, Abdelmohsen K, Cucca F, Gorospe M., Free PMC Article

    04/18/2020
    NF90 regulates HIF-1alpha/VEGF-A expression through the PI3K/Akt signaling pathway to promote angiogenesis in cervical cancer.

    Nuclear factor 90 promotes angiogenesis by regulating HIF-1α/VEGF-A expression through the PI3K/Akt signaling pathway in human cervical cancer.
    Zhang W, Xiong Z, Wei T, Li Q, Tan Y, Ling L, Feng X., Free PMC Article

    04/11/2020
    The dsRNA binding protein ILF3 as an essential host factor required for efficient translation of the central antiviral cytokine, IFNB1, and a subset of interferon-stimulated genes.

    ILF3 contributes to the establishment of the antiviral type I interferon program.
    Watson SF, Bellora N, Macias S., Free PMC Article

    03/21/2020
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