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    AQP4 aquaporin 4 [ Homo sapiens (human) ]

    Gene ID: 361, updated on 16-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Differentiated pattern of complement system activation between MOG-IgG-associated disease and AQP4-IgG-positive neuromyelitis optica spectrum disorder.

    Differentiated pattern of complement system activation between MOG-IgG-associated disease and AQP4-IgG-positive neuromyelitis optica spectrum disorder.
    Cho EB, Min JH, Waters P, Jeon M, Ju ES, Kim HJ, Kim SH, Shin HY, Kang SY, Lim YM, Oh SY, Lee HL, Sohn E, Lee SS, Oh J, Kim S, Huh SY, Cho JY, Seok JM, Kim BJ, Kim BJ., Free PMC Article

    04/12/2024
    B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.

    B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
    Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T., Free PMC Article

    03/23/2024
    Aquaporin-4 and Parkinson's Disease.

    Aquaporin-4 and Parkinson's Disease.
    Lapshina KV, Ekimova IV., Free PMC Article

    02/28/2024
    Non-coding RNAs and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders.

    Non-coding RNAs and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders.
    Yaghoobi Z, Seyed Bagher Nazeri SS, Asadi A, Derafsh E, Talebi Taheri A, Tamtaji Z, Dadgostar E, Rahmati-Dehkordi F, Aschner M, Mirzaei H, Tamtaji OR, Nabavizadeh F.

    02/23/2024
    Glymphatic system and aquaporin-4 in epilepsy.

    Glymphatic system and aquaporin‑4 in epilepsy.
    Nowicka D.

    02/15/2024
    The Expression and Role of Aquaporin 4 in Colon Cancer.

    The Expression and Role of Aquaporin 4 in Colon Cancer.
    Yamamoto A, Shimizu H, Takiguchi K, Shoda K, Shiraishi K, Furuya S, Akaike H, Kawaguchi Y, Amemiya H, Kawaida H, Mochizuki K, Kondo T, Ichikawa D.

    02/14/2024
    Renal dysfunction in AQP4 NMOSD and MS; a potential predictor of relapse and prognosis.

    Renal dysfunction in AQP4 NMOSD and MS; a potential predictor of relapse and prognosis.
    Chen Y, Wang Y, Jin R, Lv Z, Fu Y, Teng J, Wang X.

    02/1/2024
    Readthrough isoform of aquaporin-4 (AQP4) as a therapeutic target for Alzheimer's disease and other proteinopathies.

    Readthrough isoform of aquaporin-4 (AQP4) as a therapeutic target for Alzheimer's disease and other proteinopathies.
    Mohaupt P, Vialaret J, Hirtz C, Lehmann S., Free PMC Article

    11/3/2023
    Barriers to access and unmet needs to neuromyelitis optica spectrum disorders care in an Argentinean cohort.

    Barriers to access and unmet needs to neuromyelitis optica spectrum disorders care in an Argentinean cohort.
    Tkachuk V, Balbuena Aguirre ME, Alonso R, Barboza A, Liwacki SDV, Mainella C, Rojas JI, Silva BA, Tavolini D, Zanga G, López P, Delgado Garcia G, Carnero Contentti E.

    10/23/2023
    Estimated prevalence of AQP4 positive neuromyelitis optica spectrum disorder and MOG antibody associated disease in Sao Paulo, Brazil.

    Estimated prevalence of AQP4 positive neuromyelitis optica spectrum disorder and MOG antibody associated disease in São Paulo, Brazil.
    Silva GD, Apóstolos-Pereira SL, Callegaro D.

    10/23/2023
    Single nucleotide polymorphisms in aquaporin-4 associate with cognitive impairment status in people with HIV.

    Single nucleotide polymorphisms in aquaporin-4 associate with cognitive impairment status in people with HIV.
    Tice C, Zhao H, Langford D.

    08/10/2023
    The effects of AQP4 rs162009 on resting-state brain activity in Parkinson's disease.

    The effects of AQP4 rs162009 on resting-state brain activity in Parkinson's disease.
    Jiang M, Fang Y, Dai S, Si X, Wang Z, Tang J, Gao T, Liu Y, Song Z, Pu J, Zhang B., Free PMC Article

    08/9/2023
    miR-211-5p targeting MMP9 regulates the expressions of AQP4 in traumatic brain injury.

    miR-211-5p targeting MMP9 regulates the expressions of AQP4 in traumatic brain injury.
    Wang M, Yu X, Li B, Gao C, Chen Y, Zhang X, Li W, Yang L, Fan Z.

    07/20/2023
    Aquaporin-4 as a New Potential Molecular Biomarker for Prognosis of Low-Grade Glioma: Comprehensive Analysis Based on Online Platforms.

    Aquaporin-4 as a New Potential Molecular Biomarker for Prognosis of Low-Grade Glioma: Comprehensive Analysis Based on Online Platforms.
    Zhu J, Shi L, Su Y.

    06/28/2023
    AQP4 Aggravates Cognitive Impairment in Sepsis-Associated Encephalopathy through Inhibiting Nav 1.6-Mediated Astrocyte Autophagy.

    AQP4 Aggravates Cognitive Impairment in Sepsis-Associated Encephalopathy through Inhibiting Na(v) 1.6-Mediated Astrocyte Autophagy.
    Zhu DD, Huang YL, Guo SY, Li N, Yang XW, Sui AR, Wu Q, Zhang Y, Kong Y, Li QF, Zhang T, Zheng WF, Li AP, Yu J, Ma TH, Li S., Free PMC Article

    05/20/2023
    Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression.

    Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression.
    Wang R, Peng L, Xiao Y, Zhou Q, Wang Z, Tang L, Xiao H, Yang K, Liu H, Li L., Free PMC Article

    05/19/2023
    Aquaporin-4 in glymphatic system, and its implication for central nervous system disorders.

    Aquaporin-4 in glymphatic system, and its implication for central nervous system disorders.
    Peng S, Liu J, Liang C, Yang L, Wang G.

    03/23/2023
    Aquaporin-1 and Aquaporin-4 Expression in Ependyma, Choroid Plexus and Surrounding Transition Zones in the Human Brain.

    Aquaporin-1 and Aquaporin-4 Expression in Ependyma, Choroid Plexus and Surrounding Transition Zones in the Human Brain.
    Bihlmaier R, Deffner F, Mattheus U, Neckel PH, Hirt B, Mack AF., Free PMC Article

    03/1/2023
    Association of AQP4 single nucleotide polymorphisms (rs335929 and rs2075575) with Parkinson's disease: A case-control study.

    Association of AQP4 single nucleotide polymorphisms (rs335929 and rs2075575) with Parkinson's disease: A case-control study.
    Sun X, Tian Q, Yang Z, Liu Y, Li C, Hou B, Xie A.

    02/28/2023
    Reactivity to neural tissue epitopes, aquaporin 4 and heat shock protein 60 is associated with activated immune-inflammatory pathways and the onset of delirium following hip fracture surgery.

    Reactivity to neural tissue epitopes, aquaporin 4 and heat shock protein 60 is associated with activated immune-inflammatory pathways and the onset of delirium following hip fracture surgery.
    Maes M, Thisayakorn P, Thipakorn Y, Tantavisut S, Sirivichayakul S, Vojdani A.

    02/28/2023
    Epidermal growth factor activates a hypoxia-inducible factor 1alpha-microRNA-21 axis to inhibit aquaporin 4 in chronic rhinosinusitis.

    Epidermal growth factor activates a hypoxia-inducible factor 1α-microRNA-21 axis to inhibit aquaporin 4 in chronic rhinosinusitis.
    Chen J, Liu D, Yang J, Jin C, Zhao C, Cheng J.

    12/24/2022
    The role of aquaporin 4 in brain tumors: implications for pathophysiology, diagnosis and therapy.

    The role of aquaporin 4 in brain tumors: implications for pathophysiology, diagnosis and therapy.
    Behnam M, Motamedzadeh A, Aalinezhad M, Dadgostar E, Rashidi Noshabad FZ, Pourfridoni M, Raei M, Mirzaei H, Aschner M, Tamtaji OR.

    11/5/2022
    Hsa_circ_0079530/AQP4 Axis Is Related to Non-Small Cell Lung Cancer Development and Radiosensitivity.

    Hsa_circ_0079530/AQP4 Axis Is Related to Non-Small Cell Lung Cancer Development and Radiosensitivity.
    Yang X, Li M, Zhao Y, Tan X, Su J, Zhong X., Free PMC Article

    10/29/2022
    AQP4, Astrogenesis, and Hydrocephalus: A New Neurological Perspective.

    AQP4, Astrogenesis, and Hydrocephalus: A New Neurological Perspective.
    Castañeyra-Ruiz L, González-Marrero I, Hernández-Abad LG, Lee S, Castañeyra-Perdomo A, Muhonen M., Free PMC Article

    10/8/2022
    Aquaporin 4 is not present in normal porcine and human lamina cribrosa.

    Aquaporin 4 is not present in normal porcine and human lamina cribrosa.
    Kimball EC, Quillen S, Pease ME, Keuthan C, Nagalingam A, Zack DJ, Johnson TV, Quigley HA., Free PMC Article

    06/25/2022
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