| Activation of the insulin receptor by insulin-like growth factor 2. | Activation of the insulin receptor by insulin-like growth factor 2.
An W, Hall C, Li J, Hung A, Wu J, Park J, Wang L, Bai XC, Choi E., Free PMC Article | 04/17/2024 |
| The Insulin Receptor and Insulin like Growth Factor Receptor 5' UTRs Support Translation Initiation Independently of EIF4G1. | The Insulin Receptor and Insulin like Growth Factor Receptor 5' UTRs Support Translation Initiation Independently of EIF4G1.
Clark NK, Harris MT, Dahl WB, Knotts Z, Marr MT 2nd., | 02/15/2024 |
| Insulin Signaling Through the Insulin Receptor Increases Linear Growth Through Effects on Bone and the GH-IGF-1 Axis. | Insulin Signaling Through the Insulin Receptor Increases Linear Growth Through Effects on Bone and the GH-IGF-1 Axis.
Okawa MC, Tuska RM, Lightbourne M, Abel BS, Walter M, Dai Y, Cochran E, Brown RJ., Free PMC Article | 01/11/2024 |
| Association between diabetes and stress-induced hyperglycemia with skeletal muscle gene expression of INSR in critically ill patients: A prospective cohort study. | Association between diabetes and stress-induced hyperglycemia with skeletal muscle gene expression of INSR in critically ill patients: A prospective cohort study.
Bellaver P, Schaeffer AF, Dullius DP, Crispim D, Leitão CB, Rech TH. | 11/30/2023 |
| Can obesity exacerbate hyperinsulinaemia in the presence of the mutation of an insulin receptor gene? | Can obesity exacerbate hyperinsulinaemia in the presence of the mutation of an insulin receptor gene?
Calcaterra V, Zuccotti G, Mari A, Iafusco F, Maione G, Iafusco D, Tinto N. | 11/18/2023 |
| Insulin receptor-inspired soluble insulin binder. | Insulin receptor-inspired soluble insulin binder.
Mendoza C, Hanegan C, Sperry A, Vargas L, Case T, Bikman B, Mizrachi D. | 10/28/2023 |
| Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study. | Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study.
Qin C, Diaz-Gallo LM, Tang B, Wang Y, Nguyen TD, Harder A, Lu Y, Padyukov L, Askling J, Hägg S., Free PMC Article | 08/1/2023 |
| The Activation Mechanism of the Insulin Receptor: A Structural Perspective. | The Activation Mechanism of the Insulin Receptor: A Structural Perspective.
Choi E, Bai XC., Free PMC Article | 06/23/2023 |
| Associations between heredity, height, BMI, diabetes mellitus type 1 or 2 and gene variants in the insulin receptor (INSR) gene in patients with schizophrenia. | Associations between heredity, height, BMI, diabetes mellitus type 1 or 2 and gene variants in the insulin receptor (INSR) gene in patients with schizophrenia.
Melkersson K, Persson B. | 05/30/2023 |
| Sphingosine kinase 2 regulates insulin receptor trafficking in hepatocytes. | Sphingosine kinase 2 regulates insulin receptor trafficking in hepatocytes.
Aji G, Jiang S, Obulkasim H, Lu Z, Wang W, Xia P., Free PMC Article | 03/6/2023 |
| Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling. | Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling.
Nagao H, Cai W, Brandão BB, Wewer Albrechtsen NJ, Steger M, Gattu AK, Pan H, Dreyfuss JM, Wunderlich FT, Mann M, Kahn CR., Free PMC Article | 03/6/2023 |
| Unique ligand and kinase-independent roles of the insulin receptor in regulation of cell cycle, senescence and apoptosis. | Unique ligand and kinase-independent roles of the insulin receptor in regulation of cell cycle, senescence and apoptosis.
Nagao H, Jayavelu AK, Cai W, Pan H, Dreyfuss JM, Batista TM, Brandão BB, Mann M, Kahn CR., Free PMC Article | 01/28/2023 |
| The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance. | The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance.
Dall'Agnese A, Platt JM, Zheng MM, Friesen M, Dall'Agnese G, Blaise AM, Spinelli JB, Henninger JE, Tevonian EN, Hannett NM, Lazaris C, Drescher HK, Bartsch LM, Kilgore HR, Jaenisch R, Griffith LG, Cisse II, Jeppesen JF, Lee TI, Young RA., Free PMC Article | 12/17/2022 |
| Oxidative Stress Kinase Activation and Impaired Insulin Receptor Signaling Precede Overt Alzheimer's Disease Neuropathology. | Oxidative Stress Kinase Activation and Impaired Insulin Receptor Signaling Precede Overt Alzheimer's Disease Neuropathology.
Shen WB, Elahi M, Wang B, Zhan M, Yang P, Yang P. | 11/26/2022 |
| Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart. | Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.
Abdellatif M, Madeo F, Kroemer G, Sedej S., Free PMC Article | 10/8/2022 |
| Excess 11-Oxygenated Androgens in Women With Severe Insulin Resistance Are Mediated by Adrenal Insulin Receptor Signaling. | Excess 11-Oxygenated Androgens in Women With Severe Insulin Resistance Are Mediated by Adrenal Insulin Receptor Signaling.
Walzer D, Turcu AF, Jha S, Abel BS, Auchus RJ, Merke DP, Brown RJ., Free PMC Article | 08/27/2022 |
| Case Report: A Chinese Family of Type A Insulin Resistance Syndrome With Diabetes Mellitus, With a Novel Heterozygous Missense Mutation of the Insulin Receptor Gene. | Case Report: A Chinese Family of Type A Insulin Resistance Syndrome With Diabetes Mellitus, With a Novel Heterozygous Missense Mutation of the Insulin Receptor Gene.
You W, Yang J, Wang L, Liu Y, Wang W, Zhu L, Wang W, Yang J, Chen F., Free PMC Article | 08/27/2022 |
| Effect of Insulin Receptor-Knockdown on the Expression Levels of Blood-Brain Barrier Functional Proteins in Human Brain Microvascular Endothelial Cells. | Effect of Insulin Receptor-Knockdown on the Expression Levels of Blood-Brain Barrier Functional Proteins in Human Brain Microvascular Endothelial Cells.
Nagano H, Ito S, Masuda T, Ohtsuki S. | 07/9/2022 |
| Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling. | Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
Nielsen J, Brandt J, Boesen T, Hummelshøj T, Slaaby R, Schluckebier G, Nissen P. | 05/21/2022 |
| Biological functions of nuclear-localized insulin receptor (IR) on A549 lung cancer cells. | Biological functions of nuclear-localized insulin receptor (IR) on A549 lung cancer cells.
Qiu R, Miao T, Lin L, Wei Z. | 04/16/2022 |
| Missense variant in insulin receptor (Y1355H) segregates in family with fatty liver disease. | Missense variant in insulin receptor (Y1355H) segregates in family with fatty liver disease.
Luo F, Xing C, Asrani SK, Li S, Liang G, Hobbs HH, Cohen JC., Free PMC Article | 03/26/2022 |
| Gene expression of leptin, leptin receptor isoforms and inflammatory cytokines in placentas of obese women - Associations to birth weight and fetal sex. | Gene expression of leptin, leptin receptor isoforms and inflammatory cytokines in placentas of obese women - Associations to birth weight and fetal sex.
Allbrand M, Eklund D, Cao Y, Nilsson K, Lodefalk M. | 03/12/2022 |
| Insulin and the insulin receptor collaborate to promote human gastric cancer. | Insulin and the insulin receptor collaborate to promote human gastric cancer.
Saisana M, Griffin SM, May FEB., Free PMC Article | 02/26/2022 |
| Insulin-Responsive Transcription Factors. | Insulin-Responsive Transcription Factors.
Thiel G, Guethlein LA, Rössler OG., Free PMC Article | 01/22/2022 |
| Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance. | Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance.
Cen HH, Hussein B, Botezelli JD, Wang S, Zhang JA, Noursadeghi N, Jessen N, Rodrigues B, Timmons JA, Johnson JD., Free PMC Article | 01/15/2022 |