| M2 macrophage-derived exosomal miR-26b-5p regulates macrophage polarization and chondrocyte hypertrophy by targeting TLR3 and COL10A1 to alleviate osteoarthritis. | M2 macrophage-derived exosomal miR-26b-5p regulates macrophage polarization and chondrocyte hypertrophy by targeting TLR3 and COL10A1 to alleviate osteoarthritis.
Qian Y, Chu G, Zhang L, Wu Z, Wang Q, Guo JJ, Zhou F., Free PMC Article | 03/4/2024 |
| MiR-26b-3p Promotes Intestinal Motility Disorder by Targeting FZD10 to Inhibit GSK3beta/beta-Catenin Signaling and Induce Enteric Glial Cell Apoptosis. | MiR-26b-3p Promotes Intestinal Motility Disorder by Targeting FZD10 to Inhibit GSK3β/β-Catenin Signaling and Induce Enteric Glial Cell Apoptosis.
Zhan Y, Wen Y, Zheng F, Du LJ, Chen TY, Shen XL, Wu R, Tang XG. | 02/28/2024 |
| PFKFB3-driven vascular smooth muscle cell glycolysis promotes vascular calcification via the altered FoxO3 and lactate production. | PFKFB3-driven vascular smooth muscle cell glycolysis promotes vascular calcification via the altered FoxO3 and lactate production.
Chen J, Yu H, Tan X, Mok SWF, Xie Y, Wang Y, Jiang X, Macrae VE, Lan L, Fu X, Zhu D. | 09/22/2023 |
| Maternal Diabetes Deregulates the Expression of Mecp2 via miR-26b-5p in Mouse Embryonic Neural Stem Cells. | Maternal Diabetes Deregulates the Expression of Mecp2 via miR-26b-5p in Mouse Embryonic Neural Stem Cells.
Shyamasundar S, Ramya S, Kandilya D, Srinivasan DK, Bay BH, Ansari SA, Dheen ST., Free PMC Article | 06/14/2023 |
| MiR-26b-5p in small extracellular vesicles derived from dying tumor cells after irradiation enhances the metastasis promoting microenvironment in esophageal squamous cell carcinoma. | MiR-26b-5p in small extracellular vesicles derived from dying tumor cells after irradiation enhances the metastasis promoting microenvironment in esophageal squamous cell carcinoma.
Yin X, Tian M, Zhang J, Tang W, Feng L, Li Z, Zheng C, Liu C, Yan L, Yu X, Li B. | 06/18/2022 |
| MicroRNA-26b-5p Targets DAPK1 to Reduce Intestinal Ischemia/Reperfusion Injury via Inhibition of Intestinal Mucosal Cell Apoptosis. | MicroRNA-26b-5p Targets DAPK1 to Reduce Intestinal Ischemia/Reperfusion Injury via Inhibition of Intestinal Mucosal Cell Apoptosis.
Zhou B, Zhang W, Yan Z, Zhao B, Zhao J, Feng W, Chen X, Li C, Liu KX., Free PMC Article | 06/11/2022 |
| Asporin regulated by miR-26b-5p mediates chondrocyte senescence and exacerbates osteoarthritis progression via TGF-beta1/Smad2 pathway. | Asporin regulated by miR-26b-5p mediates chondrocyte senescence and exacerbates osteoarthritis progression via TGF-β1/Smad2 pathway.
Liu L, Zhao C, Zhang H, Lu Y, Luo B, Yao Z, Shao Y, Zeng H, Zeng C, Zhang R, Fang H, Pan J, Bai X, Cai D. | 06/11/2022 |
| MicroRNA-26b-5p alleviates murine collagen-induced arthritis by modulating Th17 cell plasticity. | MicroRNA-26b-5p alleviates murine collagen-induced arthritis by modulating Th17 cell plasticity.
Zhang MF, Yang P, Shen MY, Wang X, Gao NX, Zhou XP, Zhou LL, Lu Y. | 11/27/2021 |
| Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR-26b-5p and miR-140-3p binding to Gata4. | Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR-26b-5p and miR-140-3p binding to Gata4.
Li H, Xu JD, Fang XH, Zhu JN, Yang J, Pan R, Yuan SJ, Zeng N, Yang ZZ, Yang H, Wang XP, Duan JZ, Wang S, Luo JF, Wu SL, Shan ZX., Free PMC Article | 02/13/2021 |
| Mir-26b inhibits PTGS2 to activate the MAPK pathway, so as to reduce the inflammatory response and improve myocardial remodeling following myocardial infarction. | MicroRNA-26b relieves inflammatory response and myocardial remodeling of mice with myocardial infarction by suppression of MAPK pathway through binding to PTGS2.
Ge ZW, Zhu XL, Wang BC, Hu JL, Sun JJ, Wang S, Chen XJ, Meng SP, Liu L, Cheng ZY. | 12/7/2019 |
| miR-26b might play a role in promoting the transition from Kit- to Kit+ spermatogonia. | MicroRNA-26b promotes transition from Kit(-) to Kit(+) mouse spermatogonia.
Tu J, Zhang P, Shui Luk AC, Liao J, Chan WY, Qi H, Hoi-Hung AC, Lee TL. | 09/28/2019 |
| miR-26b-5p interacted with 3'UTRs of Col1a2 and CTGF, and circ_000203 could block the interactions of miR-26b-5p and 3'UTRs of Col1a2 and CTGF. | CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts.
Tang CM, Zhang M, Huang L, Hu ZQ, Zhu JN, Xiao Z, Zhang Z, Lin QX, Zheng XL, -Yang M, Wu SL, Cheng JD, Shan ZX., Free PMC Article | 10/20/2018 |
| Mir-26a and Mir-26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway. | MicroRNA-26a and -26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway.
Chen X, Xiao W, Chen W, Liu X, Wu M, Bo Q, Luo Y, Ye S, Cao Y, Liu Y., Free PMC Article | 03/31/2018 |
| The binding motif of miR26b5p in the Smad4 3'UTR was identified as UACUUGA at position 978-984. | miR-26b-5p regulates hypoxia-induced phenotypic switching of vascular smooth muscle cells via the TGF-β/Smad4 signaling pathway.
Ruan C, Lu J, Wang H, Ge Z, Zhang C, Xu M. | 02/24/2018 |
| that miR-26b exerts a role on promoting cardiomyocyte differentiation of P19 cells by controlling the canonical and non-canonical Wnt signalling | Impact of miR-26b on cardiomyocyte differentiation in P19 cells through regulating canonical/non-canonical Wnt signalling.
Wang D, Liu C, Wang Y, Wang W, Wang K, Wu X, Li Z, Zhao C, Li L, Peng L., Free PMC Article | 12/9/2017 |
| these results demonstrate that miR-26b might participate in regulating adipogenic differentiation in 3T3-L1 cells by inhibiting the PTEN expression, further highlighting the importance of miRNA in adipogenesis. | miR-26b Promotes 3T3-L1 Adipocyte Differentiation Through Targeting PTEN.
Li G, Ning C, Ma Y, Jin L, Tang Q, Li X, Li M, Liu H. | 09/23/2017 |
| Upregulation of miR26b in mouse cells downregulated the insulinlike growth factor 1 (IGF1) protein expression level and promoted beta-amyloid production. | MicroRNA-26b is upregulated in a double transgenic mouse model of Alzheimer's disease and promotes the expression of amyloid-β by targeting insulin-like growth factor 1.
Liu H, Chu W, Gong L, Gao X, Wang W. | 01/14/2017 |
| MiR-26b-5p and a 50 Hz extremely low frequency electromagnetic fields altered the expression of Cyclin D2 at both the mRNA and protein levels. | Overexpression of miR-26b-5p regulates the cell cycle by targeting CCND2 in GC-2 cells under exposure to extremely low frequency electromagnetic fields.
Liu Y, Liu WB, Liu KJ, Ao L, Cao J, Zhong JL, Liu JY., Free PMC Article | 12/17/2016 |
| Results showed that miR-26a interacts with the 3'-UTR of Col10a1 and Cd200 to inhibit the protein expression in chondrocytes. Increased miR-26a levels were accompanied by decreased amounts of extracellular matrix adaptor proteins. | MiR-26a modulates extracellular matrix homeostasis in cartilage.
Etich J, Holzer T, Pitzler L, Bluhm B, Brachvogel B. | 02/27/2016 |
| miR26a/-26b-COX-2-MIP-2 loop regulates allergic inflammation and the feedback relationship between allergic inflammation and the enhanced tumorigenic and metastatic potential | MicroRNA-26a/-26b-COX-2-MIP-2 Loop Regulates Allergic Inflammation and Allergic Inflammation-promoted Enhanced Tumorigenic and Metastatic Potential of Cancer Cells.
Kwon Y, Kim Y, Eom S, Kim M, Park D, Kim H, Noh K, Lee H, Lee YS, Choe J, Kim YM, Jeoung D., Free PMC Article | 08/22/2015 |
| SCP1 has the potential to induce cardiac hypertrophy; however, the effect is suppressed by intronic miR-26b in cardiomyocytes. miR-26b has an antagonistic effect on its host gene SCP1. | MicroRNA 26b encoded by the intron of small CTD phosphatase (SCP) 1 has an antagonistic effect on its host gene.
Sowa N, Horie T, Kuwabara Y, Baba O, Watanabe S, Nishi H, Kinoshita M, Takanabe-Mori R, Wada H, Shimatsu A, Hasegawa K, Kimura T, Ono K. | 02/9/2013 |
| Down-regulation of miR-26b in the heart is required for the up-regulation of GATA4 and the induction of pressure-induced cardiac hypertrophy. | GATA4 expression is primarily regulated via a miR-26b-dependent post-transcriptional mechanism during cardiac hypertrophy.
Han M, Yang Z, Sayed D, He M, Gao S, Lin L, Yoon S, Abdellatif M., Free PMC Article | 09/22/2012 |
| miR-26b regulates Pit-1 expression by inhibiting Lef-1 expression and may promote Pit-1 lineage differentiation during pituitary development. | MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression.
Zhang Z, Florez S, Gutierrez-Hartmann A, Martin JF, Amendt BA., Free PMC Article | 12/4/2010 |