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    LOX lysyl oxidase [ Homo sapiens (human) ]

    Gene ID: 4015, updated on 11-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Crosstalk of lysyl oxidase-like 1 and lysyl oxidase prolongs their half-lives and regulates liver fibrosis through Notch signal.

    Crosstalk of lysyl oxidase-like 1 and lysyl oxidase prolongs their half-lives and regulates liver fibrosis through Notch signal.
    Zhang N, Yang A, Zhang W, Li H, Xu A, Yan X, Han Q, Wang B, You H, Chen W., Free PMC Article

    03/14/2024
    Copper, Lysyl Oxidase Activity, and Collagen in Aqueous Humour of Primary Glaucoma: An Association with Clinical Parameters.

    Copper, Lysyl Oxidase Activity, and Collagen in Aqueous Humour of Primary Glaucoma: An Association with Clinical Parameters.
    NikhalaShree S, George RJ, Shantha B, Vijaya L, Sulochana KN, Coral K.

    01/11/2024
    Association of LOX gene G473A polymorphism with the occurrence of allergic rhinitis and efficacy of montelukast sodium in children.

    Association of LOX gene G473A polymorphism with the occurrence of allergic rhinitis and efficacy of montelukast sodium in children.
    Yao X, Liu Y, Jiao H, Ma W, Chen M.,

    12/21/2023
    MiR-590-3p Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells by Targeting Lysyl Oxidase.

    MiR-590-3p Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells by Targeting Lysyl Oxidase.
    Wang L, Zhang L, Cui LK, Yue X, Huang L, Liu N, Zhu MD, Wang ZB.

    11/13/2023
    The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice.

    The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice.
    Peymanfar Y, Mahjour F, Shrestha N, de la Cueva A, Chen Y, Huang S, Kirsch KH, Han X, Trackman PC., Free PMC Article

    06/13/2023
    Hub gene target of glioblastoma: LOX, SERPINH1 and TGFBI.

    Hub gene target of glioblastoma: LOX, SERPINH1 and TGFBI.
    Zhang S, Zhang W, Wu B, Xia L, Li L, Jin K, Zou Y, Sun C., Free PMC Article

    12/3/2022
    Elastic Laminar Reorganization Occurs with Outward Diameter Expansion during Collateral Artery Growth and Requires Lysyl Oxidase for Stabilization.

    Elastic Laminar Reorganization Occurs with Outward Diameter Expansion during Collateral Artery Growth and Requires Lysyl Oxidase for Stabilization.
    McEnaney RM, McCreary DD, Skirtich NO, Andraska EA, Sachdev U, Tzeng E., Free PMC Article

    02/26/2022
    Effect of Lysyl Oxidase G473 A Polymorphism on Lysyl Oxidase and Total Soluble Collagen Expression in Oral Submucous Fibrosis.

    Effect of Lysyl Oxidase G473 A Polymorphism on Lysyl Oxidase and Total Soluble Collagen Expression in Oral Submucous Fibrosis.
    Mukherjee S, Katarkar A, Dhariwal R, Mohanty S, Mahato B, Ray JG, Chaudhuri K., Free PMC Article

    01/22/2022
    Lysyl oxidase-variant 2 (LOX-v2) colocalizes with promyelocytic leukemia-nuclear bodies in the nucleus.

    Lysyl oxidase-variant 2 (LOX-v2) colocalizes with promyelocytic leukemia-nuclear bodies in the nucleus.
    Li C, Sharma-Bhandari A, Seo JH, Kim Y.

    01/15/2022
    Different mRNA expression patterns in keratoglobus and pellucid marginal degeneration keratocytes.

    Different mRNA expression patterns in keratoglobus and pellucid marginal degeneration keratocytes.
    Stachon T, Latta L, Seitz B, Szentmáry N.

    01/1/2022
    Genetic polymorphism of lysyl oxidase, glutathione S-transferase M1, glutathione-S-transferase T1, and glutathione S-transferase P1 genes as risk factors for lung cancer in Egyptian patients.

    Genetic polymorphism of lysyl oxidase, glutathione S-transferase M1, glutathione-S-transferase T1, and glutathione S-transferase P1 genes as risk factors for lung cancer in Egyptian patients.
    El-Deek SEM, Abdel-Ghany SM, Hana RS, Mohamed AAR, El-Melegy NT, Sayed AA.

    01/1/2022
    Severe congenital cutis laxa: Identification of novel homozygous LOX gene variants in two families.

    Severe congenital cutis laxa: Identification of novel homozygous LOX gene variants in two families.
    McKenzie F, Mina K, Callewaert B, Beyens A, Dickinson JE, Jevon G, Papadimitriou J, Diness BR, Steensberg JN, Ek J, Baynam G.

    01/1/2022
    Association with Corneal Remodeling Related Genes, ALDH3A1, LOX, and SPARC Genes Variations in Korean Keratoconus Patients.

    Association with Corneal Remodeling Related Genes, ALDH3A1, LOX, and SPARC Genes Variations in Korean Keratoconus Patients.
    Mok JW, So HR, Ha MJ, Na KS, Joo CK., Free PMC Article

    12/18/2021
    Influence of Lysyl oxidase Polymorphisms in Cancer Risk: An Updated Meta-analysis.

    Influence of Lysyl oxidase Polymorphisms in Cancer Risk: An Updated Meta-analysis.
    Mongkolrob R, Tharabenjasin P, Bualuang A, Jarjanazi H, Pabalan N.

    12/18/2021
    Peroxiredoxin-1 Tyr194 phosphorylation regulates LOX-dependent extracellular matrix remodelling in breast cancer.

    Peroxiredoxin-1 Tyr194 phosphorylation regulates LOX-dependent extracellular matrix remodelling in breast cancer.
    Attaran S, Skoko JJ, Hopkins BL, Wright MK, Wood LE, Asan A, Woo HA, Feinberg A, Neumann CA., Free PMC Article

    12/18/2021
    The prognostic value of the lysyl oxidase family in ovarian cancer.

    The prognostic value of the lysyl oxidase family in ovarian cancer.
    Ye M, Zhou J, Gao Y, Pan S, Zhu X., Free PMC Article

    10/30/2021
    Novel LOX Variants in Five Families with Aortic/Arterial Aneurysm and Dissection with Variable Connective Tissue Findings.

    Novel LOX Variants in Five Families with Aortic/Arterial Aneurysm and Dissection with Variable Connective Tissue Findings.
    Van Gucht I, Krebsova A, Diness BR, Laga S, Adlam D, Kempers M, Samani NJ, Webb TR, Baranowska AA, Van Den Heuvel L, Perik M, Luyckx I, Peeters N, Votypka P, Macek M, Meester J, Van Laer L, Verstraeten A, Loeys BL., Free PMC Article

    10/23/2021
    Serum Lysyl Oxidase Is a Potential Diagnostic Biomarker for Kidney Fibrosis.

    Serum Lysyl Oxidase Is a Potential Diagnostic Biomarker for Kidney Fibrosis.
    Zhang XQ, Li X, Zhou WQ, Liu X, Huang JL, Zhang YY, Lindholm B, Yu C.

    09/18/2021
    Regulation of lysyl oxidase expression in THP-1 cell-derived M2-like macrophages.

    Regulation of lysyl oxidase expression in THP-1 cell-derived M2-like macrophages.
    Takemoto R, Kamiya T, Atobe T, Hara H, Adachi T.

    09/4/2021
    Lysyl oxidase suppresses the inflammatory response in anterior cruciate ligament fibroblasts and promotes tissue regeneration by targeting myotrophin via the nuclear factor-kappa B pathway.

    Lysyl oxidase suppresses the inflammatory response in anterior cruciate ligament fibroblasts and promotes tissue regeneration by targeting myotrophin via the nuclear factor-kappa B pathway.
    Wang C, Sha Y, Wang S, Chi Q, Sung KLP, Xu K, Yang L.

    08/14/2021
    MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.

    MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.
    Yang YL, Tsai MC, Chang YH, Wang CC, Chu PY, Lin HY, Huang YH., Free PMC Article

    07/17/2021
    Endothelin-1 induces lysyl oxidase expression in pulmonary artery smooth muscle cells.

    Endothelin-1 induces lysyl oxidase expression in pulmonary artery smooth muscle cells.
    Maruyama H, Sakai S, Dewachter L, Dewachter C, Rondelet B, Naeije R, Ieda M.

    07/10/2021
    Lysyl Oxidase (LOX): Functional Contributions to Signaling Pathways.

    Lysyl Oxidase (LOX): Functional Contributions to Signaling Pathways.
    Laczko R, Csiszar K., Free PMC Article

    03/13/2021
    Downregulation of lysyl oxidase in venous malformations: Association with vascular destabilization and sclerotherapy.

    Downregulation of lysyl oxidase in venous malformations: Association with vascular destabilization and sclerotherapy.
    Zhu J, Shao M, Guo F, Ren J, Tang Z, Geng J, Xu Z, Jia J, Chen L, Jia Y.

    02/13/2021
    Upregulated LOX and increased collagen content associated with aggressive clinicopathological features and unfavorable outcome in oral squamous cell carcinoma.

    Upregulated LOX and increased collagen content associated with aggressive clinicopathological features and unfavorable outcome in oral squamous cell carcinoma.
    Yu M, Shen W, Shi X, Wang Q, Zhu L, Xu X, Yu J, Liu L.

    08/22/2020
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