Apolipoprotein E isoforms and their Cys-thiol modifications impact LRP1-mediated metabolism of triglyceride-rich lipoproteins. | Apolipoprotein E isoforms and their Cys-thiol modifications impact LRP1-mediated metabolism of triglyceride-rich lipoproteins. Matsuura H, Akahane S, Kaido T, Kamijo T, Sakamoto K, Yamauchi K. | 02/20/2024 |
ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells. | ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells. Lee J, Lee H, Lee H, Shin M, Shin MG, Seo J, Lee EJ, Park SA, Park S., Free PMC Article | 01/3/2024 |
Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer. | Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer. He L, Shi M, Ren S, Zhang J, Tian Y, Yang X, Liu H., Free PMC Article | 11/8/2023 |
The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells. | The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells. Henry A, Mauperin M, Devy J, Dedieu S, Chazee L, Hachet C, Terryn C, Duca L, Martiny L, Devarenne-Charpentier E, Btaouri HE., Free PMC Article | 10/5/2023 |
LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4. | LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4. Oue H, Yamazaki Y, Qiao W, Yuanxin C, Ren Y, Kurti A, Shue F, Parsons TM, Perkerson RB, Kawatani K, Wang N, Starling SC, Roy B, Mosneag IE, Aikawa T, Holm ML, Liu CC, Inoue Y, Sullivan PM, Asmann YW, Kim BY, Bu G, Kanekiyo T., Free PMC Article | 08/10/2023 |
Exome-wide analysis reveals role of LRP1 and additional novel loci in cognition. | Exome-wide analysis reveals role of LRP1 and additional novel loci in cognition. Chakraborty S, Kahali B., Free PMC Article | 06/21/2023 |
Peripheral apolipoprotein E proteins and their binding to LRP1 antagonize Alzheimer's disease pathogenesis in the brain during peripheral chronic inflammation. | Peripheral apolipoprotein E proteins and their binding to LRP1 antagonize Alzheimer's disease pathogenesis in the brain during peripheral chronic inflammation. Na H, Yang JB, Zhang Z, Gan Q, Tian H, Rajab IM, Potempa LA, Tao Q, Qiu WQ., | 05/22/2023 |
Low-density lipoprotein receptor-related protein 1 (LRP1) as an auxiliary host factor for RNA viruses. | Low-density lipoprotein receptor-related protein 1 (LRP1) as an auxiliary host factor for RNA viruses. Devignot S, Sha TW, Burkard TR, Schmerer P, Hagelkruys A, Mirazimi A, Elling U, Penninger JM, Weber F., Free PMC Article | 05/19/2023 |
Contribution of LRP1 in Human Congenital Heart Disease Correlates with Its Roles in the Outflow Tract and Atrioventricular Cushion Development. | Contribution of LRP1 in Human Congenital Heart Disease Correlates with Its Roles in the Outflow Tract and Atrioventricular Cushion Development. Arrigo AB, Zhu W, Williams KA, Guzman-Moreno C, Lo C, Lin JI., Free PMC Article | 05/5/2023 |
Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell. | Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell. Zhou W, Ma J, Zhao H, Wang Q, Guo X, Chen L, Cao Z, Xu J, Zhang B, Zhou X., Free PMC Article | 04/26/2023 |
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption. | Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption. Zhu L, Tang Y, Li XY, Kerk SA, Lyssiotis CA, Sun X, Wang Z, Cho JS, Ma J, Weiss SJ., Free PMC Article | 03/9/2023 |
LRP-1 links post-translational modifications to efficient presentation of celiac disease-specific T cell antigens. | LRP-1 links post-translational modifications to efficient presentation of celiac disease-specific T cell antigens. Loppinet E, Besser HA, Sewa AS, Yang FC, Jabri B, Khosla C., Free PMC Article | 02/4/2023 |
MT1-MMP Expression Levels and Catalytic Functions Dictate LDL Receptor-Related Protein-1 Ligand Internalization Capacity in U87 Glioblastoma Cells. | MT1-MMP Expression Levels and Catalytic Functions Dictate LDL Receptor-Related Protein-1 Ligand Internalization Capacity in U87 Glioblastoma Cells. Pratt J, Haidara K, Annabi B., Free PMC Article | 12/10/2022 |
Multitarget Activities of Muller Glial Cells and Low-Density Lipoprotein Receptor-Related Protein 1 in Proliferative Retinopathies. | Multitarget Activities of Müller Glial Cells and Low-Density Lipoprotein Receptor-Related Protein 1 in Proliferative Retinopathies. Sanchez MC, Chiabrando GA., Free PMC Article | 11/5/2022 |
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage. | A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage. Yamamoto K, Scavenius C, Meschis MM, Gremida AME, Mogensen EH, Thøgersen IB, Bonelli S, Scilabra SD, Jensen A, Santamaria S, Ahnström J, Bou-Gharios G, Enghild JJ, Nagase H. | 10/8/2022 |
Soluble low density lipoprotein receptor-related protein-1 levels in the differential diagnosis of myopericarditis versus acute coronary syndrome. | Soluble low density lipoprotein receptor-related protein-1 levels in the differential diagnosis of myopericarditis versus acute coronary syndrome. Agirbasli M, Bölen F, Konal O, Korkmaz R, Onur AI, Kartal I, Isman FK. | 10/8/2022 |
Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts. | Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts. Chun H, Kurasawa JH, Olivares P, Marakasova ES, Shestopal SA, Hassink GU, Karnaukhova E, Migliorini M, Obi JO, Smith AK, Wintrode PL, Durai P, Park K, Deredge D, Strickland DK, Sarafanov AG., Free PMC Article | 10/8/2022 |
LRP1 is a neuronal receptor for alpha-synuclein uptake and spread. | LRP1 is a neuronal receptor for α-synuclein uptake and spread. Chen K, Martens YA, Meneses A, Ryu DH, Lu W, Raulin AC, Li F, Zhao J, Chen Y, Jin Y, Linares C, Goodwin M, Li Y, Liu CC, Kanekiyo T, Holtzman DM, Golde TE, Bu G, Zhao N., Free PMC Article | 09/24/2022 |
Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy. | Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy. Yan W, Zheng L, Xu X, Hao Z, Zhang Y, Lu J, Sun Z, Dai J, Shi D, Guo B, Jiang Q., Free PMC Article | 09/17/2022 |
Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1. | Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1. Schwarz MM, Price DA, Ganaie SS, Feng A, Mishra N, Hoehl RM, Fatma F, Stubbs SH, Whelan SPJ, Cui X, Egawa T, Leung DW, Amarasinghe GK, Hartman AL., Free PMC Article | 08/27/2022 |
LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling. | LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling. Garcia-Arcos I, Park SS, Mai M, Alvarez-Buve R, Chow L, Cai H, Baumlin-Schmid N, Agudelo CW, Martinez J, Kim MD, Dabo AJ, Salathe M, Goldberg IJ, Foronjy RF., Free PMC Article | 07/30/2022 |
Pleiotropic effects of PCSK9-inhibition on hemostasis: Anti-PCSK9 reduce FVIII levels by enhancing LRP1 expression. | Pleiotropic effects of PCSK9-inhibition on hemostasis: Anti-PCSK9 reduce FVIII levels by enhancing LRP1 expression. Paciullo F, Petito E, Falcinelli E, Gresele P, Momi S. | 07/23/2022 |
LRP-1 receptor combines EGFR signalling and eHsp90alpha autocrine to support constitutive breast cancer cell motility in absence of blood supply. | LRP-1 receptor combines EGFR signalling and eHsp90α autocrine to support constitutive breast cancer cell motility in absence of blood supply. Chang C, Tang X, Mosallaei D, Chen M, Woodley DT, Schönthal AH, Li W., Free PMC Article | 07/23/2022 |
Low levels of soluble low-density lipoprotein receptor-related protein 1 in patients with type 2 diabetes mellitus and diabetic retinopathy. | Low levels of soluble low-density lipoprotein receptor-related protein 1 in patients with type 2 diabetes mellitus and diabetic retinopathy. Batu Oto B, Aykut V, Güneş M, Korkmaz R, İsman FK, Agirbasli M. | 05/7/2022 |
Deciphering the Role of the rs2651899, rs10166942, and rs11172113 Polymorphisms in Migraine: A Meta-Analysis. | Deciphering the Role of the rs2651899, rs10166942, and rs11172113 Polymorphisms in Migraine: A Meta-Analysis. Siokas V, Liampas I, Aloizou AM, Papasavva M, Bakirtzis C, Lavdas E, Liakos P, Drakoulis N, Bogdanos DP, Dardiotis E., Free PMC Article | 05/7/2022 |