| Differential regulation of MAP2 by phosphorylation events in proline-rich versus C-terminal domains. | Differential regulation of MAP2 by phosphorylation events in proline-rich versus C-terminal domains.
DeGiosio RA, Needham PG, Andrews OA, Tristan H, Grubisha MJ, Brodsky JL, Camacho C, Sweet RA., | 09/15/2023 |
| MAP2 caps tau fibrils and inhibits aggregation. | MAP2 caps tau fibrils and inhibits aggregation.
Holden MR, Krzesinski BJ, Weismiller HA, Shady JR, Margittai M., Free PMC Article | 08/4/2023 |
| Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules' physical properties and neurite morphology. | Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules' physical properties and neurite morphology.
Nishida K, Matsumura K, Tamura M, Nakamichi T, Shimamori K, Kuragano M, Kabir AMR, Kakugo A, Kotani S, Nishishita N, Tokuraku K., Free PMC Article | 06/2/2023 |
| Specific phosphorylation of microtubule-associated protein 2c by extracellular signal-regulated kinase reduces interactions at its Pro-rich regions. | Specific phosphorylation of microtubule-associated protein 2c by extracellular signal-regulated kinase reduces interactions at its Pro-rich regions.
Plucarová J, Jansen S, Narasimhan S, Laníková A, Lewitzky M, Feller SM, Žídek L., Free PMC Article | 11/19/2022 |
| Predicting Clinical Outcomes 7-10 Years after Severe Traumatic Brain Injury: Exploring the Prognostic Utility of the IMPACT Lab Model and Cerebrospinal Fluid UCH-L1 and MAP-2. | Predicting Clinical Outcomes 7-10 Years after Severe Traumatic Brain Injury: Exploring the Prognostic Utility of the IMPACT Lab Model and Cerebrospinal Fluid UCH-L1 and MAP-2.
Svingos AM, Robicsek SA, Hayes RL, Wang KK, Robertson CS, Brophy GM, Papa L, Gabrielli A, Hannay HJ, Bauer RM, Heaton SC. | 07/23/2022 |
| Methyltransferase-like (METTL)14-mediated N6-methyladenosine modification modulates retinal pigment epithelial (RPE) activity by regulating the methylation of microtubule-associated protein (MAP)2. | Methyltransferase-like (METTL)14-mediated N6-methyladenosine modification modulates retinal pigment epithelial (RPE) activity by regulating the methylation of microtubule-associated protein (MAP)2.
Yin L, Ma C, Hou S, Ma X., Free PMC Article | 04/16/2022 |
| Angiotensin II Induces Differentiation of Human Neuroblastoma Cells by Increasing MAP2 and ROS Levels. | Angiotensin II Induces Differentiation of Human Neuroblastoma Cells by Increasing MAP2 and ROS Levels.
Collazo BJ, Morales-Vázquez D, Álvarez-Del Valle J, Sierra-Pagan JE, Medina JC, Méndez-Álvarez J, Gerena Y., Free PMC Article | 01/29/2022 |
| The Cytoskeletal Elements MAP2 and NF-L Show Substantial Alterations in Different Stroke Models While Elevated Serum Levels Highlight Especially MAP2 as a Sensitive Biomarker in Stroke Patients. | The Cytoskeletal Elements MAP2 and NF-L Show Substantial Alterations in Different Stroke Models While Elevated Serum Levels Highlight Especially MAP2 as a Sensitive Biomarker in Stroke Patients.
Mages B, Fuhs T, Aleithe S, Blietz A, Hobusch C, Härtig W, Schob S, Krueger M, Michalski D., Free PMC Article | 01/1/2022 |
| Circ_001680 aggravates the malignant process of gastric carcinoma by targeting MAP2. | Circ_001680 aggravates the malignant process of gastric carcinoma by targeting MAP2.
Zhao HD, Ma Y, Wu XS, Cheng JJ, Xia ZG, Kan C, Ding XJ, Chen WD, Zhang LZ, Wang XY, Cai Y, Wang SY. | 04/24/2021 |
| Microtubule alterations may destabilize photoreceptor integrity: Age-related microtubule changes and pattern of expression of MAP-2, Tau and hyperphosphorylated Tau in aging human photoreceptor cells. | Microtubule alterations may destabilize photoreceptor integrity: Age-related microtubule changes and pattern of expression of MAP-2, Tau and hyperphosphorylated Tau in aging human photoreceptor cells.
Nag TC, Kathpalia P, Wadhwa S. | 02/2/2021 |
| Proteomics in cerebrospinal fluid and spinal cord suggests UCHL1, MAP2 and GPNMB as biomarkers and underpins importance of transcriptional pathways in amyotrophic lateral sclerosis. | Proteomics in cerebrospinal fluid and spinal cord suggests UCHL1, MAP2 and GPNMB as biomarkers and underpins importance of transcriptional pathways in amyotrophic lateral sclerosis.
Oeckl P, Weydt P, Thal DR, Weishaupt JH, Ludolph AC, Otto M. | 01/23/2021 |
| Microtubule-associated protein 2 knockdown sensitizes glioma cells to vincristine treatment. | Microtubule-associated protein 2 knockdown sensitizes glioma cells to vincristine treatment.
Yang L, Xu X, Zheng J. | 01/16/2021 |
| Increased expression of neurogenic factors in uterine fibroids. | Increased expression of neurogenic factors in uterine fibroids.
Luddi A, Marrocco C, Governini L, Semplici B, Pavone V, Capaldo A, Tosti C, Greco S, Luisi S, Ciarmela P, Petraglia F, Piomboni P. | 10/3/2020 |
| These data suggest that early levels of MAP-2 reflect severity of diffuse brain injury and predict 2-week mortality in severe traumatic brain injury patients | Temporal Profile of Microtubule-Associated Protein 2: A Novel Indicator of Diffuse Brain Injury Severity and Early Mortality after Brain Trauma.
Papa L, Robicsek SA, Brophy GM, Wang KKW, Hannay HJ, Heaton S, Schmalfuss I, Gabrielli A, Hayes RL, Robertson CS., Free PMC Article | 07/13/2019 |
| N-terminal regions of MAP2c provide important specificity to its regulatory roles and indicate a close relationship between MAP2c's biological functions and conformational behavior | Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics.
Melková K, Zapletal V, Jansen S, Nomilner E, Zachrdla M, Hritz J, Nováček J, Zweckstetter M, Jensen MR, Blackledge M, Žídek L., Free PMC Article | 03/2/2019 |
| study suggests that miR-484 and MAP2 can be utilized as predictors for the clinical diagnosis and prognosis of glioma | miR-484/MAP2/c-Myc-positive regulatory loop in glioma promotes tumor-initiating properties through ERK1/2 signaling.
Yi R, Feng J, Yang S, Huang X, Liao Y, Hu Z, Luo M. | 09/8/2018 |
| Results highlight the importance of splicing alteration in HD and suggest that MAP2 alteration contributes to dendritic atrophy. | MAP2 Splicing is Altered in Huntington's Disease.
Cabrera JR, Lucas JJ., Free PMC Article | 03/10/2018 |
| The expression of MAP2 and SYP proved most relevant to neurocognitive functioning in HIV-infected patients. | Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV.
Levine AJ, Soontornniyomkij V, Achim CL, Masliah E, Gelman BB, Sinsheimer JS, Singer EJ, Moore DJ., Free PMC Article | 01/27/2018 |
| In patients with HD, a panel using calretinin and peripherin with or without MAP-2 may be most helpful in identifying transition zones | Utility of Peripherin Versus MAP-2 and Calretinin in the Evaluation of Hirschsprung Disease.
Chisholm KM, Longacre TA. | 08/5/2017 |
| Transcriptional upregulation of microtubule-associated protein 2 is involved in the protein kinase A-induced decrease in the invasiveness of glioma cells. | Transcriptional upregulation of microtubule-associated protein 2 is involved in the protein kinase A-induced decrease in the invasiveness of glioma cells.
Zhou Y, Wu S, Liang C, Lin Y, Zou Y, Li K, Lu B, Shu M, Huang Y, Zhu W, Kang Z, Xu D, Hu J, Yan G., Free PMC Article | 08/27/2016 |
| Study reveals the presence of two selected neuronal markers, MAP-2 and SYP mRNAs and protein expression, in eutopic endometrium and in endometriotic lesions. | Expression of microtubule associated protein 2 and synaptophysin in endometrium: high levels in deep infiltrating endometriosis lesions.
Gori M, Luddi A, Belmonte G, Piomboni P, Tosti C, Funghi L, Zupi E, Lazzeri L, Petraglia F. | 07/2/2016 |
| Findings demonstrate that microtubule-associated protein 2-immunoreactivity loss is closely linked to dendritic spine pathology in schizophrenia. | Loss of Microtubule-Associated Protein 2 Immunoreactivity Linked to Dendritic Spine Loss in Schizophrenia.
Shelton MA, Newman JT, Gu H, Sampson AR, Fish KN, MacDonald ML, Moyer CE, DiBitetto JV, Dorph-Petersen KA, Penzes P, Lewis DA, Sweet RA., Free PMC Article | 05/14/2016 |
| This is the first report to analyze the correlation between ET-1-induced miRNA 133a overexpression in proteinuria resulting in MRP2 downregulation, which is a contributing factor for renal cytotoxicity. | ET-1 Induced Downregulation of MRP2 via miRNA 133a - A Marker for Tubular Nephrotoxicity?
Loeser H, von Brandenstein M, Herschung A, Schlosser M, Büttner R, Fries JW. | 05/7/2016 |
| the difference of only two amino acids in tau and MAP2 sequences may determine their different fates in tauopathies | Identification of key amino acids responsible for the distinct aggregation properties of microtubule-associated protein 2 and tau.
Xie C, Soeda Y, Shinzaki Y, In Y, Tomoo K, Ihara Y, Miyasaka T., Free PMC Article | 01/16/2016 |
| MAP2 expression is affected by actomyosin contractility during nanotopography-directed neuronal differentiation of human embryonic stem cells | Actomyosin contractility plays a role in MAP2 expression during nanotopography-directed neuronal differentiation of human embryonic stem cells.
Ankam S, Lim CK, Yim EK. | 11/21/2015 |