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    MCAM melanoma cell adhesion molecule [ Homo sapiens (human) ]

    Gene ID: 4162, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CD146 Promotes EMT-Mediated Migration and Invasion of NSCLC via PI3K/Akt Signaling Pathway.

    CD146 Promotes EMT-Mediated Migration and Invasion of NSCLC via PI3K/Akt Signaling Pathway.
    Wei N, Wu X, Yu Y, Zhou H, Cui K, Zhao X, Zhang X.

    05/24/2024
    The role of CD146 in renal disease: from experimental nephropathy to clinics.

    The role of CD146 in renal disease: from experimental nephropathy to clinics.
    Boutin L, Roger E, Gayat E, Depret F, Blot-Chabaud M, Chadjichristos CE.

    01/26/2024
    CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway.

    CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway.
    Chen J, Xu Q, Liu D, Li X, Guo M, Chen X, Liao J, Lei R, Li W, Huang H, Saw PE, Song E, Yan X, Nie Y., Free PMC Article

    11/14/2023
    MCAM+ brain endothelial cells contribute to neuroinflammation by recruiting pathogenic CD4+ T lymphocytes.

    MCAM+ brain endothelial cells contribute to neuroinflammation by recruiting pathogenic CD4+ T lymphocytes.
    Charabati M, Zandee S, Fournier AP, Tastet O, Thai K, Zaminpeyma R, Lécuyer MA, Bourbonnière L, Larouche S, Klement W, Grasmuck C, Tea F, Zierfuss B, Filali-Mouhim A, Moumdjian R, Bouthillier A, Cayrol R, Peelen E, Arbour N, Larochelle C, Prat A., Free PMC Article

    10/20/2023
    Galphai1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis.

    Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis.
    Li Y, Chai JL, Shi X, Feng Y, Li JJ, Zhou LN, Cao C, Li KR., Free PMC Article

    05/12/2023
    METCAM/MUC18 Plays a Tumor Suppressor Role in the Development of Nasopharyngeal Carcinoma Type I.

    METCAM/MUC18 Plays a Tumor Suppressor Role in the Development of Nasopharyngeal Carcinoma Type I.
    Liu YC, Chen YJ, Wu GJ., Free PMC Article

    01/28/2023
    CD146+ Endometrial-Derived Mesenchymal Stem/Stromal Cell Subpopulation Possesses Exosomal Secretomes with Strong Immunomodulatory miRNA Attributes.

    CD146+ Endometrial-Derived Mesenchymal Stem/Stromal Cell Subpopulation Possesses Exosomal Secretomes with Strong Immunomodulatory miRNA Attributes.
    Leñero C, Kaplan LD, Best TM, Kouroupis D., Free PMC Article

    01/14/2023
    CD146 at the Interface between Oxidative Stress and the Wnt Signaling Pathway in Systemic Sclerosis.

    CD146 at the Interface between Oxidative Stress and the Wnt Signaling Pathway in Systemic Sclerosis.
    Heim X, Bermudez J, Joshkon A, Kaspi E, Bachelier R, Nollet M, Vélier M, Dou L, Brodovitch A, Foucault-Bertaud A, Leroyer AS, Benyamine A, Daumas A, Granel B, Sabatier F, Dignat-George F, Blot-Chabaud M, Bardin N.

    11/26/2022
    Exosomal lncRNA PCAT1 Promotes Tumor Circulating Cell-Mediated Colorectal Cancer Liver Metastasis by Regulating the Activity of the miR-329-3p/Netrin-1-CD146 Complex.

    Exosomal lncRNA PCAT1 Promotes Tumor Circulating Cell-Mediated Colorectal Cancer Liver Metastasis by Regulating the Activity of the miR-329-3p/Netrin-1-CD146 Complex.
    Fang X, Xu Y, Li K, Liu P, Zhang H, Jiang Y, Tang J, Li Y., Free PMC Article

    10/1/2022
    Overexpression of MCAM induced by SMYD2-H3K36me2 in breast cancer stem cell properties.

    Overexpression of MCAM induced by SMYD2-H3K36me2 in breast cancer stem cell properties.
    Li X, Wang Y, Zhang Y, Liu B.

    08/27/2022
    The CD146-HIF-1alpha axis regulates epithelial cell migration and alveolar maturation in a mouse model of bronchopulmonary dysplasia.

    The CD146-HIF-1α axis regulates epithelial cell migration and alveolar maturation in a mouse model of bronchopulmonary dysplasia.
    Jin R, Gao Q, Yin C, Zou M, Lu K, Liu W, Zhu Y, Zhang M, Cheng R., Free PMC Article

    07/30/2022
    The function of CD146 in human annulus fibrosus cells and mechanism of the regulation by TGF-beta.

    The function of CD146 in human annulus fibrosus cells and mechanism of the regulation by TGF-β.
    Du J, Guo W, Häckel S, Hoppe S, Garcia JP, Alini M, Tryfonidou MA, Creemers LB, Grad S, Li Z.

    06/25/2022
    CD146(+) Pericytes Subset Isolated from Human Micro-Fragmented Fat Tissue Display a Strong Interaction with Endothelial Cells: A Potential Cell Target for Therapeutic Angiogenesis.

    CD146(+) Pericytes Subset Isolated from Human Micro-Fragmented Fat Tissue Display a Strong Interaction with Endothelial Cells: A Potential Cell Target for Therapeutic Angiogenesis.
    Manocha E, Consonni A, Baggi F, Ciusani E, Cocce V, Paino F, Tremolada C, Caruso A, Alessandri G., Free PMC Article

    06/11/2022
    Involvement of Multiple Variants of Soluble CD146 in Systemic Sclerosis: Identification of a Novel Profibrotic Factor.

    Involvement of Multiple Variants of Soluble CD146 in Systemic Sclerosis: Identification of a Novel Profibrotic Factor.
    Nollet M, Bachelier R, Joshkon A, Traboulsi W, Mahieux A, Moyon A, Muller A, Somasundaram I, Simoncini S, Peiretti F, Leroyer AS, Guillet B, Granel B, Dignat-George F, Bardin N, Foucault-Bertaud A, Blot-Chabaud M.

    06/11/2022
    Inhibition of CD146 attenuates retinal neovascularization via vascular endothelial growth factor receptor 2 signalling pathway in proliferative diabetic retinopathy.

    Inhibition of CD146 attenuates retinal neovascularization via vascular endothelial growth factor receptor 2 signalling pathway in proliferative diabetic retinopathy.
    Lin J, Cui K, Xu Y, Tang X, Shi Y, Lu X, Yang B, He Q, Yu S, Liang X.

    05/14/2022
    CD146 expression regulates osteochondrogenic differentiation of human adipose-derived stem cells.

    CD146 expression regulates osteochondrogenic differentiation of human adipose-derived stem cells.
    Scioli MG, Storti G, Bielli A, Sanchez M, Scimeca M, Gimble JM, Cervelli V, Orlandi A.

    05/7/2022
    Soluble CD146 as a Potential Target for Preventing Triple Negative Breast Cancer MDA-MB-231 Cell Growth and Dissemination.

    Soluble CD146 as a Potential Target for Preventing Triple Negative Breast Cancer MDA-MB-231 Cell Growth and Dissemination.
    Sharma A, Joshkon A, Ladjimi A, Traboulsi W, Bachelier R, Robert S, Foucault-Bertaud A, Leroyer AS, Bardin N, Somasundaram I, Blot-Chabaud M., Free PMC Article

    02/12/2022
    MCAM/MUC18/CD146 as a Multifaceted Warning Marker of Melanoma Progression in Liquid Biopsy.

    MCAM/MUC18/CD146 as a Multifaceted Warning Marker of Melanoma Progression in Liquid Biopsy.
    Rapanotti MC, Cugini E, Nuccetelli M, Terrinoni A, Di Raimondo C, Lombardo P, Costanza G, Cosio T, Rossi P, Orlandi A, Campione E, Bernardini S, Blot-Chabaud M, Bianchi L., Free PMC Article

    12/25/2021
    NG2/CSPG4, CD146/MCAM and VAP1/AOC3 are regulated by myocardin-related transcription factors in smooth muscle cells.

    NG2/CSPG4, CD146/MCAM and VAP1/AOC3 are regulated by myocardin-related transcription factors in smooth muscle cells.
    Rippe C, Morén B, Liu L, Stenkula KG, Mustaniemi J, Wennström M, Swärd K., Free PMC Article

    12/18/2021
    ImmunoPET of CD146 in Orthotopic and Metastatic Breast Cancer Models.

    ImmunoPET of CD146 in Orthotopic and Metastatic Breast Cancer Models.
    Li C, Kang L, Fan K, Ferreira CA, Becker KV, Huo N, Liu H, Yang Y, Engle JW, Wang R, Xu X, Jiang D, Cai W., Free PMC Article

    12/4/2021
    CD146 immunohistochemical staining for the separation of benign from malignant mesothelial proliferations.

    CD146 immunohistochemical staining for the separation of benign from malignant mesothelial proliferations.
    Salisbury T, Churg A.

    11/27/2021
    CD146 controls the quality of clinical grade mesenchymal stem cells from human dental pulp.

    CD146 controls the quality of clinical grade mesenchymal stem cells from human dental pulp.
    Ma L, Huang Z, Wu D, Kou X, Mao X, Shi S., Free PMC Article

    11/6/2021
    CD146, from a melanoma cell adhesion molecule to a signaling receptor.

    CD146, from a melanoma cell adhesion molecule to a signaling receptor.
    Wang Z, Xu Q, Zhang N, Du X, Xu G, Yan X., Free PMC Article

    10/9/2021
    Wnt5a promotes renal tubular inflammation in diabetic nephropathy by binding to CD146 through noncanonical Wnt signaling.

    Wnt5a promotes renal tubular inflammation in diabetic nephropathy by binding to CD146 through noncanonical Wnt signaling.
    Li X, Wen J, Dong Y, Zhang Q, Guan J, Liu F, Zhou T, Li Z, Fan Y, Wang N., Free PMC Article

    10/2/2021
    MCAM abnormal expression and clinical outcome associations are highly cancer dependent as revealed through pan-cancer analysis.

    MCAM abnormal expression and clinical outcome associations are highly cancer dependent as revealed through pan-cancer analysis.
    An Y, Wei N, Cheng X, Li Y, Liu H, Wang J, Xu Z, Sun Z, Zhang X.

    08/21/2021
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